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The map label for this gene is ycxA [H]

Identifier: 13471650

GI number: 13471650

Start: 1410944

End: 1412353

Strand: Reverse

Name: ycxA [H]

Synonym: mll1685

Alternate gene names: 13471650

Gene position: 1412353-1410944 (Counterclockwise)

Preceding gene: 13471651

Following gene: 13471649

Centisome position: 20.07

GC content: 64.33

Gene sequence:

>1410_bases
ATGGCTGGGACTCCTTTGTGGTTTGATGGTCGGAAAACTCCAGAGTGTGGCGTCGGTTCCCGGCTTCCTGTCCGCTCTGG
AGCCACGGATTTGCCAGTTCTGGCGCTGCTGCACTTCGAGAATGCGCCGATAGTGGCGCAAACGGAGGCCGGTTTTCGAG
ACCGCCGGCAGGAAACGCCTTTGACCCGAACCGACTTCAGCCGGCCAAGCCCCGGCATCGACAGCTCCTACGCCTGGATG
CGCCTGGCCATCTCGATGGTGCTGGCGACGATCGGTGCGGTCGGCATGTGGGCCGTCGTCGTGGTGCTGCCCGCCGTGCA
GGGCGAGTTCGGCGTCGACCGCGCCGCGGCATCCATGCCCTACACCGCGACCATGGTGGGCTTTGCCGCCGGCAATGTGC
TGGTCGGCCGCGCCATCGATCGCATGGGCTATTGGATCCCGGCGCTGATTTCCTCCGTGGCGCTCTCGGCCGGCCTGCTG
CTTGCCGCACTTTCGACCTCGATCCTGCAATTCACCCTTGCGCAAGGTGTGCTGATCGGTGTCGGCACGTCGGTGATCTT
CGGGCCGCTGATCGCCGATATCTCGCACTGGTTCAATCGCCGGCGCGGCGTTGCTGTCACGGCGGCGGCCGCCGGCAACT
ATCTCGCCGGCGCGCTCTGGCCAACAATCATGCCGACGCTGATCAAGGCGGAAGGCTGGCGCTTCACCTATGCGGCGATC
GGCATCTTCTGCCTGGTTACCATGGTGCCGCTGGTGCTGATGCTGCGGCGCGGTGCTCCGGAGGCCACTGCCGACGGCTC
GCCGGGAAGCCGATCGGTGCAGCCGATTCCAATGTCGCCGGCCGCGATGCAAGGGCTGCTCGTCGTCGCAGGTCTCGGCT
GCTGCGTGGCGATGTCGATGCCGCAGGTGCACATCGTCGCCTATTGCATGGATCTCGGCTACGGCATGGCACATGGCGCT
GACATGCTGTCGATCATGATGGCGGCGGGCGTCGTCAGCCGGCTTGCCTCGGGCTTTGTCGCCGATCGCATCGGCGGCGT
GAAGACGCTGCTTATCGGTTCGGTGCTGCAATGCCTGTCGCTGTTGTTCTACATACCGTTCGACGGGCTCGCCTCGCTCT
ATGTCGTGTCGCTGGTGTTCGGCCTGTCGCAAGGCGGCATCGTGCCTTGCTATGCGATCATCGTGCGCGAATATCTGCCC
GCCAAGGAGGCCGGCCAGCGTATCGGCATCGTCATGATGGCGACGATTTTCGGCATGGCGATCGGCGGCTGGATGTCCGG
CTGGATCTACGACCTGACCGGTTCCTACGCCGTAGCCTTCCTCAACGGCATCGCCTGGAATTTGCTGAACATAGGGGCGA
TCGGGCTGTTCATGTGGAAGGCAAGGCCCAGGGCTGTCATGGTAGCCTGA

Upstream 100 bases:

>100_bases
CGATCTTCTTGGCATCGTCGGCTTCGAAGATGTGATCCTCGAGATCCATGGCATTGCTATGCTCCGTCACCTCGGCCGAC
CATTTCTGCCTGCAGGGGTC

Downstream 100 bases:

>100_bases
GGCGCGCCTCGGCTTGACAATAGGCAAGGGCTGCGCGACCCCAGAGACCAAGGGTTGCGGCAACAGGCCGGTGAGATGGC
GACAGCTGAGATGATCGTAT

Product: oxalate/formate antiporter

Products: NA

Alternate protein names: ORF5 [H]

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MAGTPLWFDGRKTPECGVGSRLPVRSGATDLPVLALLHFENAPIVAQTEAGFRDRRQETPLTRTDFSRPSPGIDSSYAWM
RLAISMVLATIGAVGMWAVVVVLPAVQGEFGVDRAAASMPYTATMVGFAAGNVLVGRAIDRMGYWIPALISSVALSAGLL
LAALSTSILQFTLAQGVLIGVGTSVIFGPLIADISHWFNRRRGVAVTAAAAGNYLAGALWPTIMPTLIKAEGWRFTYAAI
GIFCLVTMVPLVLMLRRGAPEATADGSPGSRSVQPIPMSPAAMQGLLVVAGLGCCVAMSMPQVHIVAYCMDLGYGMAHGA
DMLSIMMAAGVVSRLASGFVADRIGGVKTLLIGSVLQCLSLLFYIPFDGLASLYVVSLVFGLSQGGIVPCYAIIVREYLP
AKEAGQRIGIVMMATIFGMAIGGWMSGWIYDLTGSYAVAFLNGIAWNLLNIGAIGLFMWKARPRAVMVA

Sequences:

>Translated_469_residues
MAGTPLWFDGRKTPECGVGSRLPVRSGATDLPVLALLHFENAPIVAQTEAGFRDRRQETPLTRTDFSRPSPGIDSSYAWM
RLAISMVLATIGAVGMWAVVVVLPAVQGEFGVDRAAASMPYTATMVGFAAGNVLVGRAIDRMGYWIPALISSVALSAGLL
LAALSTSILQFTLAQGVLIGVGTSVIFGPLIADISHWFNRRRGVAVTAAAAGNYLAGALWPTIMPTLIKAEGWRFTYAAI
GIFCLVTMVPLVLMLRRGAPEATADGSPGSRSVQPIPMSPAAMQGLLVVAGLGCCVAMSMPQVHIVAYCMDLGYGMAHGA
DMLSIMMAAGVVSRLASGFVADRIGGVKTLLIGSVLQCLSLLFYIPFDGLASLYVVSLVFGLSQGGIVPCYAIIVREYLP
AKEAGQRIGIVMMATIFGMAIGGWMSGWIYDLTGSYAVAFLNGIAWNLLNIGAIGLFMWKARPRAVMVA
>Mature_468_residues
AGTPLWFDGRKTPECGVGSRLPVRSGATDLPVLALLHFENAPIVAQTEAGFRDRRQETPLTRTDFSRPSPGIDSSYAWMR
LAISMVLATIGAVGMWAVVVVLPAVQGEFGVDRAAASMPYTATMVGFAAGNVLVGRAIDRMGYWIPALISSVALSAGLLL
AALSTSILQFTLAQGVLIGVGTSVIFGPLIADISHWFNRRRGVAVTAAAAGNYLAGALWPTIMPTLIKAEGWRFTYAAIG
IFCLVTMVPLVLMLRRGAPEATADGSPGSRSVQPIPMSPAAMQGLLVVAGLGCCVAMSMPQVHIVAYCMDLGYGMAHGAD
MLSIMMAAGVVSRLASGFVADRIGGVKTLLIGSVLQCLSLLFYIPFDGLASLYVVSLVFGLSQGGIVPCYAIIVREYLPA
KEAGQRIGIVMMATIFGMAIGGWMSGWIYDLTGSYAVAFLNGIAWNLLNIGAIGLFMWKARPRAVMVA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Homo sapiens, GI42475555, Length=286, Percent_Identity=24.4755244755245, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI5730045, Length=322, Percent_Identity=25.776397515528, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1789969, Length=327, Percent_Identity=22.6299694189602, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324882, Length=407, Percent_Identity=20.1474201474201, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6324453, Length=309, Percent_Identity=23.9482200647249, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322628, Length=245, Percent_Identity=26.9387755102041, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49435; Mature: 49304

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGTPLWFDGRKTPECGVGSRLPVRSGATDLPVLALLHFENAPIVAQTEAGFRDRRQETP
CCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHEEECCCCEEEECCCCHHHHHHCCC
LTRTDFSRPSPGIDSSYAWMRLAISMVLATIGAVGMWAVVVVLPAVQGEFGVDRAAASMP
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCC
YTATMVGFAAGNVLVGRAIDRMGYWIPALISSVALSAGLLLAALSTSILQFTLAQGVLIG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEE
VGTSVIFGPLIADISHWFNRRRGVAVTAAAAGNYLAGALWPTIMPTLIKAEGWRFTYAAI
CCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
GIFCLVTMVPLVLMLRRGAPEATADGSPGSRSVQPIPMSPAAMQGLLVVAGLGCCVAMSM
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
PQVHIVAYCMDLGYGMAHGADMLSIMMAAGVVSRLASGFVADRIGGVKTLLIGSVLQCLS
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LLFYIPFDGLASLYVVSLVFGLSQGGIVPCYAIIVREYLPAKEAGQRIGIVMMATIFGMA
HHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHH
IGGWMSGWIYDLTGSYAVAFLNGIAWNLLNIGAIGLFMWKARPRAVMVA
HHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
>Mature Secondary Structure 
AGTPLWFDGRKTPECGVGSRLPVRSGATDLPVLALLHFENAPIVAQTEAGFRDRRQETP
CCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHEEECCCCEEEECCCCHHHHHHCCC
LTRTDFSRPSPGIDSSYAWMRLAISMVLATIGAVGMWAVVVVLPAVQGEFGVDRAAASMP
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCC
YTATMVGFAAGNVLVGRAIDRMGYWIPALISSVALSAGLLLAALSTSILQFTLAQGVLIG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEE
VGTSVIFGPLIADISHWFNRRRGVAVTAAAAGNYLAGALWPTIMPTLIKAEGWRFTYAAI
CCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
GIFCLVTMVPLVLMLRRGAPEATADGSPGSRSVQPIPMSPAAMQGLLVVAGLGCCVAMSM
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
PQVHIVAYCMDLGYGMAHGADMLSIMMAAGVVSRLASGFVADRIGGVKTLLIGSVLQCLS
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LLFYIPFDGLASLYVVSLVFGLSQGGIVPCYAIIVREYLPAKEAGQRIGIVMMATIFGMA
HHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHH
IGGWMSGWIYDLTGSYAVAFLNGIAWNLLNIGAIGLFMWKARPRAVMVA
HHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8355609; 8969502; 9384377 [H]