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The map label for this gene is gntR [H]

Identifier: 13471649

GI number: 13471649

Start: 1409775

End: 1410809

Strand: Reverse

Name: gntR [H]

Synonym: mll1683

Alternate gene names: 13471649

Gene position: 1410809-1409775 (Counterclockwise)

Preceding gene: 13471650

Following gene: 13471648

Centisome position: 20.05

GC content: 67.05

Gene sequence:

>1035_bases
ATGGCGTTGATCAAGCCGCGCTCGCGACGGGGCGGCGGCCGCCCGACCATAGCGGATGTCGCGCGCAAGGCCGGCGTTGG
CGCCATCACCGTGTCGCGGGCGCTGCGCGAGCCGGAGCGCGTCTCGGAGGAATTGCGCCGTCAGATCCAGGCCGCCGTCG
ACGAGCTCGGCTATGTGCCGGACCCCAATGCGCGGGCGCTGGCCTCGGCGCGCGCCGAAGTGTTCGGCGTGCTGGTGCCG
TCGCTGACCAACAACGTCTTTGCCGAAGTGGTGCGCGGCATCTATGACAGCCTGTCGGACAGCCCGTTCCGCATCCAGCT
TGGCAACACCCATTATTCCGGCCTCGAGGAGGAGCGGCTCTTGCAGCTGTTCGGCTCGCAGCGGCCGGCAGCGCTGATCG
TGGCCGGCATCGACCAGACGCCAACCTCGCGGAAACTGCTCGAAAATGCCGGCTGCCCGGTGGTGCAGGTGATGGAGACC
GGGCCCGATCCCGTCGACATGATGGTCGGCTTCTCGCATTTCGACGGCGGCAGGACGGCGACCGAGCACTTGATCGAGGC
GGGGTATCGCCGCATCGGCTTCATCGGCGCACGCATGGACCCGCGCTCGCAGCGGCGCCTCGCAGGCTATCGCGCGGCGA
TGGAGAAGCCCGGGCTGTTCGACCCGCGCCTTGTCACCACCACGCCGCTGTTGTCCAGCGTGCCGCTCGGGCGAGAACTG
TTTCGCGATGCCCTGGCCAAGATGCCGACGCTCGACGGCGTGTTCTGCAACAATGACGATATCGCGCTCGGCGTGCTGTT
CGAGTGCCACCGCGCGGCGATCGATGTGCCGAAGACCATCGGCATTGTCGGCTTCAACGACCTCGACATGATGCAGGTGG
CGTTTCCCTCGATCACCAGCATCCGCACGCATCGCTATGAAATCGGCAGGCGGGCGGTGGCCATGGCATTGTCGGCGATC
GCCGGTAACAGGCCGGAACAGCGGATCGTCGACCTCGGATTCGAACTCAAGCGCCGCGAGAGCACAGCCCGCTGA

Upstream 100 bases:

>100_bases
GCGACCCCAGAGACCAAGGGTTGCGGCAACAGGCCGGTGAGATGGCGACAGCTGAGATGATCGTATTGCGGGCGCGCTTG
GGCGGCCATATGCGCGGGCG

Downstream 100 bases:

>100_bases
ACACGCTTTTTAGAGCGCGCTCAAATGGCGCTTTACACAACGCTATGGTAGCGCTACCATTTTAGCGAACGAGCCTCGCC
TCAGAAGTGCTGCGCTTGTT

Product: transcriptional regulator GntR

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MALIKPRSRRGGGRPTIADVARKAGVGAITVSRALREPERVSEELRRQIQAAVDELGYVPDPNARALASARAEVFGVLVP
SLTNNVFAEVVRGIYDSLSDSPFRIQLGNTHYSGLEEERLLQLFGSQRPAALIVAGIDQTPTSRKLLENAGCPVVQVMET
GPDPVDMMVGFSHFDGGRTATEHLIEAGYRRIGFIGARMDPRSQRRLAGYRAAMEKPGLFDPRLVTTTPLLSSVPLGREL
FRDALAKMPTLDGVFCNNDDIALGVLFECHRAAIDVPKTIGIVGFNDLDMMQVAFPSITSIRTHRYEIGRRAVAMALSAI
AGNRPEQRIVDLGFELKRRESTAR

Sequences:

>Translated_344_residues
MALIKPRSRRGGGRPTIADVARKAGVGAITVSRALREPERVSEELRRQIQAAVDELGYVPDPNARALASARAEVFGVLVP
SLTNNVFAEVVRGIYDSLSDSPFRIQLGNTHYSGLEEERLLQLFGSQRPAALIVAGIDQTPTSRKLLENAGCPVVQVMET
GPDPVDMMVGFSHFDGGRTATEHLIEAGYRRIGFIGARMDPRSQRRLAGYRAAMEKPGLFDPRLVTTTPLLSSVPLGREL
FRDALAKMPTLDGVFCNNDDIALGVLFECHRAAIDVPKTIGIVGFNDLDMMQVAFPSITSIRTHRYEIGRRAVAMALSAI
AGNRPEQRIVDLGFELKRRESTAR
>Mature_343_residues
ALIKPRSRRGGGRPTIADVARKAGVGAITVSRALREPERVSEELRRQIQAAVDELGYVPDPNARALASARAEVFGVLVPS
LTNNVFAEVVRGIYDSLSDSPFRIQLGNTHYSGLEEERLLQLFGSQRPAALIVAGIDQTPTSRKLLENAGCPVVQVMETG
PDPVDMMVGFSHFDGGRTATEHLIEAGYRRIGFIGARMDPRSQRRLAGYRAAMEKPGLFDPRLVTTTPLLSSVPLGRELF
RDALAKMPTLDGVFCNNDDIALGVLFECHRAAIDVPKTIGIVGFNDLDMMQVAFPSITSIRTHRYEIGRRAVAMALSAIA
GNRPEQRIVDLGFELKRRESTAR

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=325, Percent_Identity=40.9230769230769, Blast_Score=224, Evalue=4e-60,
Organism=Escherichia coli, GI1790715, Length=329, Percent_Identity=34.6504559270517, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI1790369, Length=321, Percent_Identity=28.3489096573209, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1790194, Length=328, Percent_Identity=29.2682926829268, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1788474, Length=322, Percent_Identity=28.5714285714286, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787948, Length=333, Percent_Identity=28.5285285285285, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1789202, Length=300, Percent_Identity=29.3333333333333, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789068, Length=305, Percent_Identity=27.2131147540984, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787906, Length=266, Percent_Identity=30.0751879699248, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1786540, Length=330, Percent_Identity=24.8484848484848, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787580, Length=329, Percent_Identity=23.1003039513678, Blast_Score=78, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37648; Mature: 37517

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALIKPRSRRGGGRPTIADVARKAGVGAITVSRALREPERVSEELRRQIQAAVDELGYVP
CCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
DPNARALASARAEVFGVLVPSLTNNVFAEVVRGIYDSLSDSPFRIQLGNTHYSGLEEERL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHH
LQLFGSQRPAALIVAGIDQTPTSRKLLENAGCPVVQVMETGPDPVDMMVGFSHFDGGRTA
HHHHCCCCCCEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHCCCHHCCCCHHH
TEHLIEAGYRRIGFIGARMDPRSQRRLAGYRAAMEKPGLFDPRLVTTTPLLSSVPLGREL
HHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEECCHHHHCCCCCHHH
FRDALAKMPTLDGVFCNNDDIALGVLFECHRAAIDVPKTIGIVGFNDLDMMQVAFPSITS
HHHHHHHCCCCCCEEECCCCEEEHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCHHH
IRTHRYEIGRRAVAMALSAIAGNRPEQRIVDLGFELKRRESTAR
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHCCCC
>Mature Secondary Structure 
ALIKPRSRRGGGRPTIADVARKAGVGAITVSRALREPERVSEELRRQIQAAVDELGYVP
CCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCC
DPNARALASARAEVFGVLVPSLTNNVFAEVVRGIYDSLSDSPFRIQLGNTHYSGLEEERL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHH
LQLFGSQRPAALIVAGIDQTPTSRKLLENAGCPVVQVMETGPDPVDMMVGFSHFDGGRTA
HHHHCCCCCCEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHCCCHHCCCCHHH
TEHLIEAGYRRIGFIGARMDPRSQRRLAGYRAAMEKPGLFDPRLVTTTPLLSSVPLGREL
HHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEECCHHHHCCCCCHHH
FRDALAKMPTLDGVFCNNDDIALGVLFECHRAAIDVPKTIGIVGFNDLDMMQVAFPSITS
HHHHHHHCCCCCCEEECCCCEEEHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCHHH
IRTHRYEIGRRAVAMALSAIAGNRPEQRIVDLGFELKRRESTAR
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]