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The map label for this gene is appC [H]

Identifier: 13471628

GI number: 13471628

Start: 1376243

End: 1377400

Strand: Reverse

Name: appC [H]

Synonym: mll1657

Alternate gene names: 13471628

Gene position: 1377400-1376243 (Counterclockwise)

Preceding gene: 13471629

Following gene: 13471627

Centisome position: 19.58

GC content: 61.66

Gene sequence:

>1158_bases
ATGCAGGTCCAATATATCAGTGCCTTCACCGTCATTCTCGAAGTGCTGTCGCGCTTCTGGCCGGTCTGGATCGCGCTCAT
CATCGTCATGGGGGCGAGCTTCGCCTACAAGAAGAAGCTGGCGCTCTACGGGCAGCTGTTCGACAGCGGGGTCGGCATCG
TCGGCGTCGGCATCTGCCTGTTCTGGCTGTTCACGGCGATCTTCGCATCGACCATCTCGCCTTTCGATCCGCTGGCACAG
GTCCCGGTGATGAAGGACATGCTGCCCGGCGCCATCGAGCCGCAATCAGGGCTTGTCTATCTGTTCGGTGGCGACAAGCT
GGCACGCGACGTGTTTTCACGCATGGTCTATGGCAGCCAGATCGTGCTGATCATCGCGCCGGCGGCGACCGGCTTCGCGC
TGATGGTCGGCATCACGCTAGGCCTGCCTGCCGGCTATTACGGCGGCAAGATCGATACCGTGCTGTCGTTCCTGGCCAAC
CTTGTGCTGGCCTTCCCGGTGATCCTGCTGTTCTACCTCTTGGTGACGCCGGGCATCATGGACACGCCGATCCCCTATGC
CATGGCCGGCGTGTTCTTCCTGTTTCCGATCATCTTCTTCAGCGTGCTGTTCTGGACGCGCTACAAAAACCGGCCAGATC
GGCTGTACATCCTGCTCGGCCTGACGCTGATCATAGGCGGCTGGATCTATCTCGGCCTTGTCTTCGACAGGGACCCGCTG
CACATCGTCCACATCGATCCCAACCAGCTCAACATCTTCGTGGCCGTGGTGTTTGCCTCCAGCCCGGGCGTGTTCCGCAT
CGTGCGCGGCTTGGTGATGGACATCAAGACGCGCGACTATGTGGCGGCGGCGCAGACGCGCGGTGAATCACCCTGGTACA
TCATGCTGTGGGAAATCCTGCCCAATGCACGCGGACCGCTGATCGTCGATGCCTGCCTGCGCATCGGCTACACAACGATC
CTGCTCGGCACGCTCGGCTATTTCGGCCTCGGCCTGGCACCGGAAAGCCCCGACTGGGGCACGGCGATCAAGGACGCCAG
CCGGCTGCTGCGCTCCTTCATCCATCCGGCGTTGCCGCCGACGATCGCGCTGATGTCGTTCGTGCTGGGGCTCAATCTCT
TGGCCGACTCGCTGCGTGAGCAATCGATGAAAGACTGA

Upstream 100 bases:

>100_bases
GCTGGTCTCGGTGTTCATCGTCTTGATCACACAGCTCATTTCCGATGTCGGCTACGCGTTTCTCAATCCGCGTATCAGAG
TTCAGTAGGGGGCGAAGCGG

Downstream 100 bases:

>100_bases
TTGACGGGCTCCGGCCCGCATCTGGTAGAATTTGGATTGGAGCGACCCATGAACGAGGCAGTTCGAAATCCCGCAGAGCC
GATCATCGAGATCGAAAACC

Product: permease protein of dipeptide ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MQVQYISAFTVILEVLSRFWPVWIALIIVMGASFAYKKKLALYGQLFDSGVGIVGVGICLFWLFTAIFASTISPFDPLAQ
VPVMKDMLPGAIEPQSGLVYLFGGDKLARDVFSRMVYGSQIVLIIAPAATGFALMVGITLGLPAGYYGGKIDTVLSFLAN
LVLAFPVILLFYLLVTPGIMDTPIPYAMAGVFFLFPIIFFSVLFWTRYKNRPDRLYILLGLTLIIGGWIYLGLVFDRDPL
HIVHIDPNQLNIFVAVVFASSPGVFRIVRGLVMDIKTRDYVAAAQTRGESPWYIMLWEILPNARGPLIVDACLRIGYTTI
LLGTLGYFGLGLAPESPDWGTAIKDASRLLRSFIHPALPPTIALMSFVLGLNLLADSLREQSMKD

Sequences:

>Translated_385_residues
MQVQYISAFTVILEVLSRFWPVWIALIIVMGASFAYKKKLALYGQLFDSGVGIVGVGICLFWLFTAIFASTISPFDPLAQ
VPVMKDMLPGAIEPQSGLVYLFGGDKLARDVFSRMVYGSQIVLIIAPAATGFALMVGITLGLPAGYYGGKIDTVLSFLAN
LVLAFPVILLFYLLVTPGIMDTPIPYAMAGVFFLFPIIFFSVLFWTRYKNRPDRLYILLGLTLIIGGWIYLGLVFDRDPL
HIVHIDPNQLNIFVAVVFASSPGVFRIVRGLVMDIKTRDYVAAAQTRGESPWYIMLWEILPNARGPLIVDACLRIGYTTI
LLGTLGYFGLGLAPESPDWGTAIKDASRLLRSFIHPALPPTIALMSFVLGLNLLADSLREQSMKD
>Mature_385_residues
MQVQYISAFTVILEVLSRFWPVWIALIIVMGASFAYKKKLALYGQLFDSGVGIVGVGICLFWLFTAIFASTISPFDPLAQ
VPVMKDMLPGAIEPQSGLVYLFGGDKLARDVFSRMVYGSQIVLIIAPAATGFALMVGITLGLPAGYYGGKIDTVLSFLAN
LVLAFPVILLFYLLVTPGIMDTPIPYAMAGVFFLFPIIFFSVLFWTRYKNRPDRLYILLGLTLIIGGWIYLGLVFDRDPL
HIVHIDPNQLNIFVAVVFASSPGVFRIVRGLVMDIKTRDYVAAAQTRGESPWYIMLWEILPNARGPLIVDACLRIGYTTI
LLGTLGYFGLGLAPESPDWGTAIKDASRLLRSFIHPALPPTIALMSFVLGLNLLADSLREQSMKD

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=315, Percent_Identity=27.9365079365079, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1787760, Length=137, Percent_Identity=33.5766423357664, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789964, Length=134, Percent_Identity=32.8358208955224, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 42435; Mature: 42435

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVQYISAFTVILEVLSRFWPVWIALIIVMGASFAYKKKLALYGQLFDSGVGIVGVGICL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
FWLFTAIFASTISPFDPLAQVPVMKDMLPGAIEPQSGLVYLFGGDKLARDVFSRMVYGSQ
HHHHHHHHHHHCCCCCHHHHCCHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCE
IVLIIAPAATGFALMVGITLGLPAGYYGGKIDTVLSFLANLVLAFPVILLFYLLVTPGIM
EEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DTPIPYAMAGVFFLFPIIFFSVLFWTRYKNRPDRLYILLGLTLIIGGWIYLGLVFDRDPL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHEECCCCE
HIVHIDPNQLNIFVAVVFASSPGVFRIVRGLVMDIKTRDYVAAAQTRGESPWYIMLWEIL
EEEEECCCCEEEEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEHHHC
PNARGPLIVDACLRIGYTTILLGTLGYFGLGLAPESPDWGTAIKDASRLLRSFIHPALPP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCH
TIALMSFVLGLNLLADSLREQSMKD
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQVQYISAFTVILEVLSRFWPVWIALIIVMGASFAYKKKLALYGQLFDSGVGIVGVGICL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHH
FWLFTAIFASTISPFDPLAQVPVMKDMLPGAIEPQSGLVYLFGGDKLARDVFSRMVYGSQ
HHHHHHHHHHHCCCCCHHHHCCHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCE
IVLIIAPAATGFALMVGITLGLPAGYYGGKIDTVLSFLANLVLAFPVILLFYLLVTPGIM
EEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DTPIPYAMAGVFFLFPIIFFSVLFWTRYKNRPDRLYILLGLTLIIGGWIYLGLVFDRDPL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHEECCCCE
HIVHIDPNQLNIFVAVVFASSPGVFRIVRGLVMDIKTRDYVAAAQTRGESPWYIMLWEIL
EEEEECCCCEEEEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEHHHC
PNARGPLIVDACLRIGYTTILLGTLGYFGLGLAPESPDWGTAIKDASRLLRSFIHPALPP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCH
TIALMSFVLGLNLLADSLREQSMKD
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]