| Definition | Mesorhizobium loti MAFF303099 chromosome, complete genome. |
|---|---|
| Accession | NC_002678 |
| Length | 7,036,071 |
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The map label for this gene is yusZ [H]
Identifier: 13471581
GI number: 13471581
Start: 1329893
End: 1330732
Strand: Direct
Name: yusZ [H]
Synonym: mlr1595
Alternate gene names: 13471581
Gene position: 1329893-1330732 (Clockwise)
Preceding gene: 13471580
Following gene: 13471584
Centisome position: 18.9
GC content: 65.6
Gene sequence:
>840_bases ATGACAAACAAGGTTTGGTTCATCACCGGATCGTCGAAGGGTTTTGGCCGTGTTTGGGCCGAGGCTGCACTGGCGCGCGG CGACCGCGTTGCCGCGACCGCCCGTGACGCTGGCACGCTCGCCGATCTGGTCGAGAAGTATGGCGACAACATCGCCGCGA TAAAGCTCGACGTCACCGACAAGAAAGCCGTCGATACGGCCGTTGCCGAGGCGCACAAGCGCTTTGGCCGGCTCGACGTC GTCATCAACAATGCCGGCTATGGCCATTTCGGCGCCATTGAGGAGGTCAGCGAGCAGGAAGCCCGCGACCAGATCGAAAC CAATGTGTTCGGCGCGCTGTGGGTCACGCAGGCGGTACTGCCGATCATGCGGGCCCAGCGTTCCGGCCGCATCATCCAGA TCTCGTCGATCGGCGGCGTCAACGCCTTCGCCTCGCTCGGCCTCTACCACGCCTCGAAATGGGCGCTGGAAGCCTTCAGC CAGTCGCTCAGCATCGAGGTCGCGGAATTCGGCATCCATGTCACGCTGGTCGAGCCAGGCGGCTTCTCCACCGACTGGTC CGGTGCCTCAGCCAAGGTCTCCAAGCCGATCGAGGCCTACGCGCCCGCCCGCGCCAAGATGGCCGAGCGCCGCGCCAATT CGGTCGCCGGCGACCCCGAAGCCACCGGTCCGGCGATGCTGGCCATCGTCGACGCCGCCGAGCCGCCGCTGCGGGTGTTC TTCGGCGATGGCGGCCTGCCGATGATCCGCCAGGAATACGCCAACCGCCTCGCCACCTGGGACAAATGGGACCACGTGTC CGTCATGGCACAAGGCGCGAACAAGAACCGCAAGGGCTGA
Upstream 100 bases:
>100_bases TCGCCTCTGGAAAATCACCGTATAGACCGTATATGCCCGAAAGCGGAGAAGCCTCCGCTTTCGTCCAAAATTGCGCCCGC AGGGGCAAGGATTCCACATC
Downstream 100 bases:
>100_bases GGCAAGCTTCTGCTACGCCGCTCAAGGGGCGGCGTAGCCCTTCGGCCACGATTCAACCGCGCAGCTATGTCTGGTAAATC CACTGCTCCGGCACCCGCGC
Product: short chain dehydrogenase
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: ORFA [H]
Number of amino acids: Translated: 279; Mature: 278
Protein sequence:
>279_residues MTNKVWFITGSSKGFGRVWAEAALARGDRVAATARDAGTLADLVEKYGDNIAAIKLDVTDKKAVDTAVAEAHKRFGRLDV VINNAGYGHFGAIEEVSEQEARDQIETNVFGALWVTQAVLPIMRAQRSGRIIQISSIGGVNAFASLGLYHASKWALEAFS QSLSIEVAEFGIHVTLVEPGGFSTDWSGASAKVSKPIEAYAPARAKMAERRANSVAGDPEATGPAMLAIVDAAEPPLRVF FGDGGLPMIRQEYANRLATWDKWDHVSVMAQGANKNRKG
Sequences:
>Translated_279_residues MTNKVWFITGSSKGFGRVWAEAALARGDRVAATARDAGTLADLVEKYGDNIAAIKLDVTDKKAVDTAVAEAHKRFGRLDV VINNAGYGHFGAIEEVSEQEARDQIETNVFGALWVTQAVLPIMRAQRSGRIIQISSIGGVNAFASLGLYHASKWALEAFS QSLSIEVAEFGIHVTLVEPGGFSTDWSGASAKVSKPIEAYAPARAKMAERRANSVAGDPEATGPAMLAIVDAAEPPLRVF FGDGGLPMIRQEYANRLATWDKWDHVSVMAQGANKNRKG >Mature_278_residues TNKVWFITGSSKGFGRVWAEAALARGDRVAATARDAGTLADLVEKYGDNIAAIKLDVTDKKAVDTAVAEAHKRFGRLDVV INNAGYGHFGAIEEVSEQEARDQIETNVFGALWVTQAVLPIMRAQRSGRIIQISSIGGVNAFASLGLYHASKWALEAFSQ SLSIEVAEFGIHVTLVEPGGFSTDWSGASAKVSKPIEAYAPARAKMAERRANSVAGDPEATGPAMLAIVDAAEPPLRVFF GDGGLPMIRQEYANRLATWDKWDHVSVMAQGANKNRKG
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7657478, Length=257, Percent_Identity=32.6848249027237, Blast_Score=118, Evalue=7e-27, Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=33.1632653061224, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI223718074, Length=289, Percent_Identity=30.1038062283737, Blast_Score=108, Evalue=4e-24, Organism=Homo sapiens, GI40548397, Length=201, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=6e-21, Organism=Homo sapiens, GI214010158, Length=201, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=6e-21, Organism=Homo sapiens, GI214010156, Length=201, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=6e-21, Organism=Homo sapiens, GI22758144, Length=201, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=6e-21, Organism=Homo sapiens, GI19743808, Length=212, Percent_Identity=30.6603773584906, Blast_Score=98, Evalue=9e-21, Organism=Homo sapiens, GI150247226, Length=189, Percent_Identity=35.978835978836, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI50726952, Length=186, Percent_Identity=38.1720430107527, Blast_Score=92, Evalue=5e-19, Organism=Homo sapiens, GI40254992, Length=186, Percent_Identity=31.7204301075269, Blast_Score=92, Evalue=7e-19, Organism=Homo sapiens, GI7706318, Length=223, Percent_Identity=29.1479820627803, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI59889578, Length=146, Percent_Identity=36.3013698630137, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI4503817, Length=200, Percent_Identity=27, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI119392083, Length=184, Percent_Identity=29.8913043478261, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI22507405, Length=187, Percent_Identity=32.0855614973262, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI44680136, Length=188, Percent_Identity=29.2553191489362, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI44680133, Length=188, Percent_Identity=29.2553191489362, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI17738292, Length=188, Percent_Identity=29.2553191489362, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI66933014, Length=164, Percent_Identity=34.1463414634146, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4504503, Length=162, Percent_Identity=30.2469135802469, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=29.8429319371728, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI5031737, Length=191, Percent_Identity=29.8429319371728, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI32483357, Length=191, Percent_Identity=27.7486910994764, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI157739938, Length=190, Percent_Identity=27.3684210526316, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI210032110, Length=171, Percent_Identity=25.1461988304094, Blast_Score=69, Evalue=7e-12, Organism=Homo sapiens, GI31542939, Length=191, Percent_Identity=29.3193717277487, Blast_Score=69, Evalue=7e-12, Organism=Homo sapiens, GI32455239, Length=184, Percent_Identity=30.9782608695652, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI5031765, Length=184, Percent_Identity=30.9782608695652, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1787335, Length=215, Percent_Identity=34.8837209302326, Blast_Score=111, Evalue=4e-26, Organism=Escherichia coli, GI87082100, Length=200, Percent_Identity=32, Blast_Score=94, Evalue=9e-21, Organism=Escherichia coli, GI1786701, Length=204, Percent_Identity=32.3529411764706, Blast_Score=94, Evalue=9e-21, Organism=Escherichia coli, GI1787820, Length=175, Percent_Identity=30.8571428571429, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI87082160, Length=197, Percent_Identity=26.9035532994924, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=29.0836653386454, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1789378, Length=186, Percent_Identity=30.1075268817204, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1786812, Length=182, Percent_Identity=29.6703296703297, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1788459, Length=207, Percent_Identity=27.0531400966184, Blast_Score=63, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17562904, Length=245, Percent_Identity=28.9795918367347, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17538486, Length=206, Percent_Identity=32.0388349514563, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17562906, Length=213, Percent_Identity=31.4553990610329, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562910, Length=235, Percent_Identity=27.6595744680851, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17562908, Length=200, Percent_Identity=32.5, Blast_Score=81, Evalue=7e-16, Organism=Caenorhabditis elegans, GI71997402, Length=189, Percent_Identity=31.7460317460317, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI193204405, Length=219, Percent_Identity=30.5936073059361, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560332, Length=201, Percent_Identity=30.8457711442786, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI72000259, Length=270, Percent_Identity=27.7777777777778, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI71994604, Length=195, Percent_Identity=27.6923076923077, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17559104, Length=230, Percent_Identity=26.0869565217391, Blast_Score=78, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17560676, Length=198, Percent_Identity=26.2626262626263, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17565030, Length=282, Percent_Identity=30.1418439716312, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17551412, Length=210, Percent_Identity=30.4761904761905, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17557780, Length=189, Percent_Identity=29.1005291005291, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17559962, Length=215, Percent_Identity=29.7674418604651, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI115534660, Length=184, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI71994600, Length=195, Percent_Identity=28.7179487179487, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17507613, Length=194, Percent_Identity=30.4123711340206, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI32563809, Length=249, Percent_Identity=26.9076305220884, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17570069, Length=191, Percent_Identity=29.8429319371728, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17538480, Length=215, Percent_Identity=27.4418604651163, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17531453, Length=194, Percent_Identity=30.4123711340206, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17563726, Length=199, Percent_Identity=28.1407035175879, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17559964, Length=217, Percent_Identity=29.4930875576037, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17560220, Length=198, Percent_Identity=30.3030303030303, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17568967, Length=189, Percent_Identity=31.7460317460317, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17560150, Length=195, Percent_Identity=26.1538461538462, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=31.4720812182741, Blast_Score=94, Evalue=2e-20, Organism=Saccharomyces cerevisiae, GI6322861, Length=194, Percent_Identity=30.4123711340206, Blast_Score=78, Evalue=2e-15, Organism=Saccharomyces cerevisiae, GI6322067, Length=185, Percent_Identity=27.5675675675676, Blast_Score=67, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6322226, Length=187, Percent_Identity=28.8770053475936, Blast_Score=65, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322227, Length=238, Percent_Identity=23.5294117647059, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI23397609, Length=186, Percent_Identity=32.258064516129, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI24651139, Length=144, Percent_Identity=35.4166666666667, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI21356301, Length=199, Percent_Identity=31.6582914572864, Blast_Score=83, Evalue=3e-16, Organism=Drosophila melanogaster, GI28571526, Length=191, Percent_Identity=29.8429319371728, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=30.6122448979592, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI21357041, Length=188, Percent_Identity=27.6595744680851, Blast_Score=81, Evalue=9e-16, Organism=Drosophila melanogaster, GI24643142, Length=207, Percent_Identity=29.4685990338164, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI116007236, Length=198, Percent_Identity=28.2828282828283, Blast_Score=78, Evalue=7e-15, Organism=Drosophila melanogaster, GI21355319, Length=194, Percent_Identity=28.3505154639175, Blast_Score=77, Evalue=9e-15, Organism=Drosophila melanogaster, GI24639444, Length=190, Percent_Identity=31.0526315789474, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24644339, Length=187, Percent_Identity=27.807486631016, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI24640442, Length=189, Percent_Identity=29.1005291005291, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI24580925, Length=197, Percent_Identity=29.4416243654822, Blast_Score=75, Evalue=7e-14, Organism=Drosophila melanogaster, GI28571387, Length=196, Percent_Identity=30.1020408163265, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI116007238, Length=184, Percent_Identity=28.2608695652174, Blast_Score=72, Evalue=6e-13, Organism=Drosophila melanogaster, GI18859837, Length=189, Percent_Identity=29.6296296296296, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI281364494, Length=200, Percent_Identity=28, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI21355631, Length=171, Percent_Identity=24.5614035087719, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24584748, Length=207, Percent_Identity=28.5024154589372, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI161076933, Length=207, Percent_Identity=28.5024154589372, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI281364892, Length=175, Percent_Identity=29.7142857142857, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24584744, Length=257, Percent_Identity=24.5136186770428, Blast_Score=69, Evalue=5e-12, Organism=Drosophila melanogaster, GI28574402, Length=257, Percent_Identity=24.5136186770428, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI24581726, Length=178, Percent_Identity=25.8426966292135, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI17737361, Length=201, Percent_Identity=25.3731343283582, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24641232, Length=198, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=8e-11, Organism=Drosophila melanogaster, GI24663911, Length=227, Percent_Identity=27.7533039647577, Blast_Score=64, Evalue=1e-10,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 29917; Mature: 29786
Theoretical pI: Translated: 7.10; Mature: 7.10
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 1.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTNKVWFITGSSKGFGRVWAEAALARGDRVAATARDAGTLADLVEKYGDNIAAIKLDVTD CCCEEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCEEEEEEECCC KKAVDTAVAEAHKRFGRLDVVINNAGYGHFGAIEEVSEQEARDQIETNVFGALWVTQAVL CHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH PIMRAQRSGRIIQISSIGGVNAFASLGLYHASKWALEAFSQSLSIEVAEFGIHVTLVEPG HHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEHEEEEEEEECCC GFSTDWSGASAKVSKPIEAYAPARAKMAERRANSVAGDPEATGPAMLAIVDAAEPPLRVF CCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEE FGDGGLPMIRQEYANRLATWDKWDHVSVMAQGANKNRKG ECCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCC >Mature Secondary Structure TNKVWFITGSSKGFGRVWAEAALARGDRVAATARDAGTLADLVEKYGDNIAAIKLDVTD CCEEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCEEEEEEECCC KKAVDTAVAEAHKRFGRLDVVINNAGYGHFGAIEEVSEQEARDQIETNVFGALWVTQAVL CHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH PIMRAQRSGRIIQISSIGGVNAFASLGLYHASKWALEAFSQSLSIEVAEFGIHVTLVEPG HHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEHEEEEEEEECCC GFSTDWSGASAKVSKPIEAYAPARAKMAERRANSVAGDPEATGPAMLAIVDAAEPPLRVF CCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEE FGDGGLPMIRQEYANRLATWDKWDHVSVMAQGANKNRKG ECCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9353931; 9384377; 8396117 [H]