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The map label for this gene is ilvE [H]

Identifier: 13471580

GI number: 13471580

Start: 1328799

End: 1329761

Strand: Direct

Name: ilvE [H]

Synonym: mlr1594

Alternate gene names: 13471580

Gene position: 1328799-1329761 (Clockwise)

Preceding gene: 13471578

Following gene: 13471581

Centisome position: 18.89

GC content: 65.32

Gene sequence:

>963_bases
ATGGACCAGACGACGGCAACACAGGCTTCAAAGCCGCTGCCCACAGTCGGCGACCGCCACGTCGACCCGCATTCCTACCC
CGACGGCATCGCCTTCCTCGACGGCCAGTATCTGCCGATGTCGCAAGCCAAGGTGTCGGTGCTGGACTGGGGCTTCCTGC
ATTCCGACGCCACCTACGACACGGTGCATGTCTGGAACGGCCGCTTCTTCCGCCTCGACCTGCATCTCGACCGCTTCTTC
GGCGGACTGGAAAAGCTGCGCATGACCATCCCCTTCGACAGGGATGGCGTGGCCGAGATCCTGCACAATTGTGTCGCCCT
TTCGGGCCATCGCGCCGCCTATGTCGAAATGCTGTGCACGCGCGGCGCATCGCCGACCTTCAGCCGCGATCCGCGCCAGG
CGATCAACCGCTTCATGGCCTTCGCCGTACCCTTCGGCTCGGTCGCCAATGCCGAGCAGTTGCAGCGCGGCCTGCGCGTC
GCCATCAGCGACAAGGTGCGCATCCCGCCGGCTTCGGTCGATCCGTCGATCAAGAACTACCATTGGCTCGATCTGGTGCG
CGGCCTCTACGACGCCTATGACAGCGGTGCGGAGACCGCGCTCATTCTCGACTTCAACGGCAATGTCGCCGAGGGCCCGG
GCTTCAACGTCTTCTGCGTCAAGGACGGCAAACTGTCGACGCCGGCCATCGGCGTGCTGCCCGGCATCACGCGCCGCACA
GTCTTCGATCTCTGCGCCGAAGAAGGTCTTGCCGCCGCCGCCGCCGATGTCAGCGTCGCCGCGCTCAAGGCGGCCGACGA
GGTCTTCATCACCTCGACCGCCGGCGGCATCATGCCGGTGACCGAGATCGACGGCGCGGCGATCGCCGACGGCAAGGTCG
GGCCGGTTACCAGCCGGCTAATGGCGCTCTACTGGCAAAAGCACGACGATCCGGCCTGGTCGTCTCAGGTGAAGTATCCC
TGA

Upstream 100 bases:

>100_bases
TGGACCGTCATGGAGGACGAACAGCGCCAGACGGCTGGCCCTACGCCTTCTGTCCGGGGCCGGTAGGCTGATGACCCGTC
CCGCCCGCGAGGAGGCCCTG

Downstream 100 bases:

>100_bases
TCAAAGGGCGTCCGTTCAAAAAGATTCCCCCTCGCCTCTGGAAAATCACCGTATAGACCGTATATGCCCGAAAGCGGAGA
AGCCTCCGCTTTCGTCCAAA

Product: branched-chain amino acid transferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MDQTTATQASKPLPTVGDRHVDPHSYPDGIAFLDGQYLPMSQAKVSVLDWGFLHSDATYDTVHVWNGRFFRLDLHLDRFF
GGLEKLRMTIPFDRDGVAEILHNCVALSGHRAAYVEMLCTRGASPTFSRDPRQAINRFMAFAVPFGSVANAEQLQRGLRV
AISDKVRIPPASVDPSIKNYHWLDLVRGLYDAYDSGAETALILDFNGNVAEGPGFNVFCVKDGKLSTPAIGVLPGITRRT
VFDLCAEEGLAAAAADVSVAALKAADEVFITSTAGGIMPVTEIDGAAIADGKVGPVTSRLMALYWQKHDDPAWSSQVKYP

Sequences:

>Translated_320_residues
MDQTTATQASKPLPTVGDRHVDPHSYPDGIAFLDGQYLPMSQAKVSVLDWGFLHSDATYDTVHVWNGRFFRLDLHLDRFF
GGLEKLRMTIPFDRDGVAEILHNCVALSGHRAAYVEMLCTRGASPTFSRDPRQAINRFMAFAVPFGSVANAEQLQRGLRV
AISDKVRIPPASVDPSIKNYHWLDLVRGLYDAYDSGAETALILDFNGNVAEGPGFNVFCVKDGKLSTPAIGVLPGITRRT
VFDLCAEEGLAAAAADVSVAALKAADEVFITSTAGGIMPVTEIDGAAIADGKVGPVTSRLMALYWQKHDDPAWSSQVKYP
>Mature_320_residues
MDQTTATQASKPLPTVGDRHVDPHSYPDGIAFLDGQYLPMSQAKVSVLDWGFLHSDATYDTVHVWNGRFFRLDLHLDRFF
GGLEKLRMTIPFDRDGVAEILHNCVALSGHRAAYVEMLCTRGASPTFSRDPRQAINRFMAFAVPFGSVANAEQLQRGLRV
AISDKVRIPPASVDPSIKNYHWLDLVRGLYDAYDSGAETALILDFNGNVAEGPGFNVFCVKDGKLSTPAIGVLPGITRRT
VFDLCAEEGLAAAAADVSVAALKAADEVFITSTAGGIMPVTEIDGAAIADGKVGPVTSRLMALYWQKHDDPAWSSQVKYP

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=301, Percent_Identity=27.5747508305648, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 34743; Mature: 34743

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQTTATQASKPLPTVGDRHVDPHSYPDGIAFLDGQYLPMSQAKVSVLDWGFLHSDATYD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEECEEECCCCCCC
TVHVWNGRFFRLDLHLDRFFGGLEKLRMTIPFDRDGVAEILHNCVALSGHRAAYVEMLCT
EEEEECCEEEEEEEEHHHHHCCHHHEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
RGASPTFSRDPRQAINRFMAFAVPFGSVANAEQLQRGLRVAISDKVRIPPASVDPSIKNY
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCEEEECCCEECCCCCCCCCCCCC
HWLDLVRGLYDAYDSGAETALILDFNGNVAEGPGFNVFCVKDGKLSTPAIGVLPGITRRT
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHH
VFDLCAEEGLAAAAADVSVAALKAADEVFITSTAGGIMPVTEIDGAAIADGKVGPVTSRL
HHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCEECCCCCCHHHHHH
MALYWQKHDDPAWSSQVKYP
HHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MDQTTATQASKPLPTVGDRHVDPHSYPDGIAFLDGQYLPMSQAKVSVLDWGFLHSDATYD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEECEEECCCCCCC
TVHVWNGRFFRLDLHLDRFFGGLEKLRMTIPFDRDGVAEILHNCVALSGHRAAYVEMLCT
EEEEECCEEEEEEEEHHHHHCCHHHEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
RGASPTFSRDPRQAINRFMAFAVPFGSVANAEQLQRGLRVAISDKVRIPPASVDPSIKNY
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCEEEECCCEECCCCCCCCCCCCC
HWLDLVRGLYDAYDSGAETALILDFNGNVAEGPGFNVFCVKDGKLSTPAIGVLPGITRRT
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHH
VFDLCAEEGLAAAAADVSVAALKAADEVFITSTAGGIMPVTEIDGAAIADGKVGPVTSRL
HHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCEECCCCCCHHHHHH
MALYWQKHDDPAWSSQVKYP
HHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]