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The map label for this gene is mrdB [H]

Identifier: 13471550

GI number: 13471550

Start: 1294614

End: 1295765

Strand: Reverse

Name: mrdB [H]

Synonym: mll1555

Alternate gene names: 13471550

Gene position: 1295765-1294614 (Counterclockwise)

Preceding gene: 13471551

Following gene: 13471549

Centisome position: 18.42

GC content: 63.54

Gene sequence:

>1152_bases
ATGCAGAGCCGTCTCGATAAAAGTCCTGTCGCAACCTGGTGGTGGACGATCGATCGCTGGTTCCTGGCGGCGTTCCTGTC
GCTGATGGGGCTGGGCATCGTCCTGTCCTTCGCCGCCAGTCCCGCGGTCGCCGAACGCATCGGCCTCGACAGTTTCCACT
TCGCCACCAGGCAGATCATCTTCACTGTGCCGGCGCTCGGCGTGATGCTGGCCGTCTCCTTCCTCGATTCCAGGGAGATC
CGGCGCATGTCGCTGATCATGCTGTGCCTGATGCTGGTGCTGATGGTGGCGGTGCTTTATATCGGCGTCGAGGTGAAGGG
CGCGCGGCGCTGGGTCTCGCTGGCCGGCCTGTCGATCCAGCCGTCCGAGTTCCTGAAGCCGGCCTTCGTCATCATGTGCG
CCTGGCTGTTCGCCGAACACAAGCGCCAGCCCGACATTCCGGGCAATCTGTTCGCCATGCTGCTTCTGGTGCTGGTCGTG
TCGCTGCTGGTGGCGCAGCCGGACCTCGGCCAGACCATGCTGACGACAGGCACCTGGGGCATCATGTTCTTCATGGCGGG
ACTGCCCTGGCTGTGGATCATCGTGCTGGGCGCTGCCGGCGTCGGCGGCGTCTTCGCTGCCTATACGGTGTTTCCGCACG
TTGCCTTGCGCATCGACAAGTTCCTCACCGGCGAAGGCGATACGTTCCAGGTCGACATGGGACGCGACGCGCTGATCAAT
GGCGGCTGGTTCGGCGTCGGCCCAGGCGAGGGCACGGTCAAGCGGGTCATCCCCGACAGCCACGCCGACTTCGTCTTCTC
GGTCGCTGGCGAGGAGTTCGGGCTGATCATGTGCTTCTTCATCATGTCGATCTTCGCCTTCATCGTGCTGCGCGGCCTCA
ACACGGCGCTCAAGGAACATGACGATTTCACCCGTTATGCGGTCGGCGGTCTCGTCACCGTGTTCGGTCTGCAGGCCGTC
ATCAACATGTGCGTCAACCTGCAGCTGGTGCCGGCCAAGGGCATGACGCTGCCCTTCATCTCCTATGGCGGTTCCTCGCA
GATCGCCATCGCCATTTCGATGGGCATGGTTCTGGCGCTGACCCGCAAGCGGCCGGAGAAGCGCAAGCAGATGGGTTTTG
CGCTGCCACAGCGCACCTTGCCGGCGGAGTGA

Upstream 100 bases:

>100_bases
CCAGTTTCGACCAGTTCAAGAATTTCGAAGTTCGCGGCGAAGCCTTCAGGCAAGCTGCGAGCGCTATAGATGGCGTCAAA
CCCATCGGAGGGGCACGATA

Downstream 100 bases:

>100_bases
CATGGCGAGAGGCGTCATCCTACTCGCGGCGGGCGGAACCGGCGGACATCTGTTTCCGGCCGAGGCGCTGGCGCATGAGC
TGAACGGGCGCGGCTGGACG

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MQSRLDKSPVATWWWTIDRWFLAAFLSLMGLGIVLSFAASPAVAERIGLDSFHFATRQIIFTVPALGVMLAVSFLDSREI
RRMSLIMLCLMLVLMVAVLYIGVEVKGARRWVSLAGLSIQPSEFLKPAFVIMCAWLFAEHKRQPDIPGNLFAMLLLVLVV
SLLVAQPDLGQTMLTTGTWGIMFFMAGLPWLWIIVLGAAGVGGVFAAYTVFPHVALRIDKFLTGEGDTFQVDMGRDALIN
GGWFGVGPGEGTVKRVIPDSHADFVFSVAGEEFGLIMCFFIMSIFAFIVLRGLNTALKEHDDFTRYAVGGLVTVFGLQAV
INMCVNLQLVPAKGMTLPFISYGGSSQIAIAISMGMVLALTRKRPEKRKQMGFALPQRTLPAE

Sequences:

>Translated_383_residues
MQSRLDKSPVATWWWTIDRWFLAAFLSLMGLGIVLSFAASPAVAERIGLDSFHFATRQIIFTVPALGVMLAVSFLDSREI
RRMSLIMLCLMLVLMVAVLYIGVEVKGARRWVSLAGLSIQPSEFLKPAFVIMCAWLFAEHKRQPDIPGNLFAMLLLVLVV
SLLVAQPDLGQTMLTTGTWGIMFFMAGLPWLWIIVLGAAGVGGVFAAYTVFPHVALRIDKFLTGEGDTFQVDMGRDALIN
GGWFGVGPGEGTVKRVIPDSHADFVFSVAGEEFGLIMCFFIMSIFAFIVLRGLNTALKEHDDFTRYAVGGLVTVFGLQAV
INMCVNLQLVPAKGMTLPFISYGGSSQIAIAISMGMVLALTRKRPEKRKQMGFALPQRTLPAE
>Mature_383_residues
MQSRLDKSPVATWWWTIDRWFLAAFLSLMGLGIVLSFAASPAVAERIGLDSFHFATRQIIFTVPALGVMLAVSFLDSREI
RRMSLIMLCLMLVLMVAVLYIGVEVKGARRWVSLAGLSIQPSEFLKPAFVIMCAWLFAEHKRQPDIPGNLFAMLLLVLVV
SLLVAQPDLGQTMLTTGTWGIMFFMAGLPWLWIIVLGAAGVGGVFAAYTVFPHVALRIDKFLTGEGDTFQVDMGRDALIN
GGWFGVGPGEGTVKRVIPDSHADFVFSVAGEEFGLIMCFFIMSIFAFIVLRGLNTALKEHDDFTRYAVGGLVTVFGLQAV
INMCVNLQLVPAKGMTLPFISYGGSSQIAIAISMGMVLALTRKRPEKRKQMGFALPQRTLPAE

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=364, Percent_Identity=28.8461538461538, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1786853, Length=296, Percent_Identity=29.0540540540541, Blast_Score=108, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 42009; Mature: 42009

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSRLDKSPVATWWWTIDRWFLAAFLSLMGLGIVLSFAASPAVAERIGLDSFHFATRQII
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHH
FTVPALGVMLAVSFLDSREIRRMSLIMLCLMLVLMVAVLYIGVEVKGARRWVSLAGLSIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHCCCCCC
PSEFLKPAFVIMCAWLFAEHKRQPDIPGNLFAMLLLVLVVSLLVAQPDLGQTMLTTGTWG
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHH
IMFFMAGLPWLWIIVLGAAGVGGVFAAYTVFPHVALRIDKFLTGEGDTFQVDMGRDALIN
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEC
GGWFGVGPGEGTVKRVIPDSHADFVFSVAGEEFGLIMCFFIMSIFAFIVLRGLNTALKEH
CCEEECCCCCCCEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DDFTRYAVGGLVTVFGLQAVINMCVNLQLVPAKGMTLPFISYGGSSQIAIAISMGMVLAL
CCHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCEECEEECCCCCCEEEEEHHHHHHHH
TRKRPEKRKQMGFALPQRTLPAE
HHCCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQSRLDKSPVATWWWTIDRWFLAAFLSLMGLGIVLSFAASPAVAERIGLDSFHFATRQII
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHH
FTVPALGVMLAVSFLDSREIRRMSLIMLCLMLVLMVAVLYIGVEVKGARRWVSLAGLSIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHCCCCCC
PSEFLKPAFVIMCAWLFAEHKRQPDIPGNLFAMLLLVLVVSLLVAQPDLGQTMLTTGTWG
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHH
IMFFMAGLPWLWIIVLGAAGVGGVFAAYTVFPHVALRIDKFLTGEGDTFQVDMGRDALIN
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEC
GGWFGVGPGEGTVKRVIPDSHADFVFSVAGEEFGLIMCFFIMSIFAFIVLRGLNTALKEH
CCEEECCCCCCCEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DDFTRYAVGGLVTVFGLQAVINMCVNLQLVPAKGMTLPFISYGGSSQIAIAISMGMVLAL
CCHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCEECEEECCCCCCEEEEEHHHHHHHH
TRKRPEKRKQMGFALPQRTLPAE
HHCCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]