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The map label for this gene is murG

Identifier: 13471549

GI number: 13471549

Start: 1293485

End: 1294612

Strand: Reverse

Name: murG

Synonym: mll1554

Alternate gene names: 13471549

Gene position: 1294612-1293485 (Counterclockwise)

Preceding gene: 13471550

Following gene: 13471548

Centisome position: 18.4

GC content: 68.44

Gene sequence:

>1128_bases
ATGGCGAGAGGCGTCATCCTACTCGCGGCGGGCGGAACCGGCGGACATCTGTTTCCGGCCGAGGCGCTGGCGCATGAGCT
GAACGGGCGCGGCTGGACGGTGCATCTGGCGACTGACGACCGCGCCGAGCGATTTGCCGGCCATTTCCCGGCTGCCGCAG
TCCATCCGATCCAGTCGGCGACGATGGGCTCGAAAAATCCGATCGCCGTGCTCGGCGCCTTCTGGAAAATCTGGCGCGGC
GTGCGCCAGGCCTCGACCATTATCGGACGGATCAAGCCGGACGCGGTGGTCGGTTTTGGCGGCTATCCGACCCTGCCGCC
GCTCTATGCGGCGACGCGGCGCAAGGTGCCGACGCTGATCCATGAGCAGAACGCGGTGATGGGGCGCGCCAACAGGGCGC
TGGCCGGCCGTGTCGATGCCATAGCCGGCGGCTTCCTGCCGCAGGATACGAGTGCCGCCGGCGAAAAGACGGTGACGACG
GGCAATCCGGTTCGGCCGGCGGTGCTGGAAGCGGCCAAGACGCCTTATGCGGCATCGACGGGGCAAGAGCCGTTCCGCCT
GCTGGTGTTCGGCGGCAGCCAGGGCGCGCAATTCTTTTCCGATGCCATGCCGGGCGCCATCGCGCTGCTTTCCGATGCAC
AGCGCAAACGGCTGGTGATCACCCAGCAGGCGCGCGCGGATGACGTGGCGCGGGTGAAGACGGCCTATGCCGCGCTTGGC
GTCGCCGTCGAGGTCTCGCCCTTCTTCACCGACATGGCGGCGCGCATGGCCGCTGCCCATCTGGTGATCTCGCGCTCCGG
TGCTTCGACCGTCTCGGAGATCGCCGTCATCGGCCGGCCGGCGCTGCTGGTGCCCTATCCCTTTGCGCTCGACCACGACC
AGGCGGCGAACGCGGCGGCCCTTGCCGCCGCCGGCGGCGGCGAGGTGCACCCGCAATCGACGCTGTCGCCCGAGCGCATC
GCGGCCCTGATTGGCGGGCTGATGGACAATCCCGAGCGGCTGGCGGCGATGGCCGCGGGCGCGAAATCGGTCGGCAGGCC
GGACGCGGCACGGTTGCTCGCCGATCTCACAGAGGCTATTGCGTCCCAAAAAACCGTTTCGGATTTCAAGAAAGGGACGC
AAGCATGA

Upstream 100 bases:

>100_bases
ATTTCGATGGGCATGGTTCTGGCGCTGACCCGCAAGCGGCCGGAGAAGCGCAAGCAGATGGGTTTTGCGCTGCCACAGCG
CACCTTGCCGGCGGAGTGAC

Downstream 100 bases:

>100_bases
AGATGCCGCAGACCATCGGCCTTGTGCATTTCATCGGCATTGGCGGCATCGGCATGAGCGGCATCGCCGAGGTGCTGCAC
AATCTCGGTTACAAGGTGCA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MARGVILLAAGGTGGHLFPAEALAHELNGRGWTVHLATDDRAERFAGHFPAAAVHPIQSATMGSKNPIAVLGAFWKIWRG
VRQASTIIGRIKPDAVVGFGGYPTLPPLYAATRRKVPTLIHEQNAVMGRANRALAGRVDAIAGGFLPQDTSAAGEKTVTT
GNPVRPAVLEAAKTPYAASTGQEPFRLLVFGGSQGAQFFSDAMPGAIALLSDAQRKRLVITQQARADDVARVKTAYAALG
VAVEVSPFFTDMAARMAAAHLVISRSGASTVSEIAVIGRPALLVPYPFALDHDQAANAAALAAAGGGEVHPQSTLSPERI
AALIGGLMDNPERLAAMAAGAKSVGRPDAARLLADLTEAIASQKTVSDFKKGTQA

Sequences:

>Translated_375_residues
MARGVILLAAGGTGGHLFPAEALAHELNGRGWTVHLATDDRAERFAGHFPAAAVHPIQSATMGSKNPIAVLGAFWKIWRG
VRQASTIIGRIKPDAVVGFGGYPTLPPLYAATRRKVPTLIHEQNAVMGRANRALAGRVDAIAGGFLPQDTSAAGEKTVTT
GNPVRPAVLEAAKTPYAASTGQEPFRLLVFGGSQGAQFFSDAMPGAIALLSDAQRKRLVITQQARADDVARVKTAYAALG
VAVEVSPFFTDMAARMAAAHLVISRSGASTVSEIAVIGRPALLVPYPFALDHDQAANAAALAAAGGGEVHPQSTLSPERI
AALIGGLMDNPERLAAMAAGAKSVGRPDAARLLADLTEAIASQKTVSDFKKGTQA
>Mature_374_residues
ARGVILLAAGGTGGHLFPAEALAHELNGRGWTVHLATDDRAERFAGHFPAAAVHPIQSATMGSKNPIAVLGAFWKIWRGV
RQASTIIGRIKPDAVVGFGGYPTLPPLYAATRRKVPTLIHEQNAVMGRANRALAGRVDAIAGGFLPQDTSAAGEKTVTTG
NPVRPAVLEAAKTPYAASTGQEPFRLLVFGGSQGAQFFSDAMPGAIALLSDAQRKRLVITQQARADDVARVKTAYAALGV
AVEVSPFFTDMAARMAAAHLVISRSGASTVSEIAVIGRPALLVPYPFALDHDQAANAAALAAAGGGEVHPQSTLSPERIA
ALIGGLMDNPERLAAMAAGAKSVGRPDAARLLADLTEAIASQKTVSDFKKGTQA

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=361, Percent_Identity=37.1191135734072, Blast_Score=168, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_RHILO (Q98KB3)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_103115.1
- ProteinModelPortal:   Q98KB3
- SMR:   Q98KB3
- GeneID:   1225778
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll1554
- NMPDR:   fig|266835.1.peg.1220
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38797; Mature: 38666

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARGVILLAAGGTGGHLFPAEALAHELNGRGWTVHLATDDRAERFAGHFPAAAVHPIQSA
CCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEEECCHHHHHHHCCCCCHHHCCHHHH
TMGSKNPIAVLGAFWKIWRGVRQASTIIGRIKPDAVVGFGGYPTLPPLYAATRRKVPTLI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCHHH
HEQNAVMGRANRALAGRVDAIAGGFLPQDTSAAGEKTVTTGNPVRPAVLEAAKTPYAAST
HHCCHHHHCCCHHHHCCHHHHHCCCCCCCCCCCCCCEECCCCCCCHHHHHHHCCCCCCCC
GQEPFRLLVFGGSQGAQFFSDAMPGAIALLSDAQRKRLVITQQARADDVARVKTAYAALG
CCCCEEEEEEECCCCHHHHHHCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHC
VAVEVSPFFTDMAARMAAAHLVISRSGASTVSEIAVIGRPALLVPYPFALDHDQAANAAA
EEEEECHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHH
LAAAGGGEVHPQSTLSPERIAALIGGLMDNPERLAAMAAGAKSVGRPDAARLLADLTEAI
EEECCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCHHHCCCCHHHHHHHHHHHHH
ASQKTVSDFKKGTQA
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
ARGVILLAAGGTGGHLFPAEALAHELNGRGWTVHLATDDRAERFAGHFPAAAVHPIQSA
CCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEEECCHHHHHHHCCCCCHHHCCHHHH
TMGSKNPIAVLGAFWKIWRGVRQASTIIGRIKPDAVVGFGGYPTLPPLYAATRRKVPTLI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCHHH
HEQNAVMGRANRALAGRVDAIAGGFLPQDTSAAGEKTVTTGNPVRPAVLEAAKTPYAAST
HHCCHHHHCCCHHHHCCHHHHHCCCCCCCCCCCCCCEECCCCCCCHHHHHHHCCCCCCCC
GQEPFRLLVFGGSQGAQFFSDAMPGAIALLSDAQRKRLVITQQARADDVARVKTAYAALG
CCCCEEEEEEECCCCHHHHHHCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHC
VAVEVSPFFTDMAARMAAAHLVISRSGASTVSEIAVIGRPALLVPYPFALDHDQAANAAA
EEEEECHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHH
LAAAGGGEVHPQSTLSPERIAALIGGLMDNPERLAAMAAGAKSVGRPDAARLLADLTEAI
EEECCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCHHHCCCCHHHHHHHHHHHHH
ASQKTVSDFKKGTQA
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968