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The map label for this gene is murB

Identifier: 13471547

GI number: 13471547

Start: 1291126

End: 1292088

Strand: Reverse

Name: murB

Synonym: mll1552

Alternate gene names: 13471547

Gene position: 1292088-1291126 (Counterclockwise)

Preceding gene: 13471548

Following gene: 13471546

Centisome position: 18.36

GC content: 63.45

Gene sequence:

>963_bases
ATGCACGGCCAGGCCCTGATCGACAGACTTGGTGACCGGCTTGCCGGCCTGCGCGGCCGTCTCACGCCAAATGCCGAGAT
GGACAAGATCACCTGGTTCCGCGCCGGCGGCCTGGCAGAGGTGTTTTTCCAGCCGGCCGATGAAGAAGACCTTGCCGCGT
TCCTGCGCGCGGTTCCTGAAGAAATCCCCCTGACGATTGTCGGCGTCGGTTCGAACCTTTTGGTCAGAGACGGGGGCATT
CCAGGCTTCGTCATCCGGCTTTCGGCCAAGGGCTTTGGTGAGGCCGAGATCGTTTCGCCGATCAGGATCAAGGCGGGTGC
CGCCACGCCCGACAAGCGTGTCGCGGCCTTGGCGCTGGAAGCCGGCATTGGTGGCTTCCATTTCTACCACGGCATTCCGG
GCGCCATCGGTGGGGCGCTGAGGATGAATGCCGGCGCCAATGGCGTGGAGACGCGCGAGCGCGTGGTCGAGGTGCGTGCG
CTCGACCGCAAGGGCAATGTCCAGACGATGAGCAATGCCGAGATGGGCTATGCCTATCGCCATTCGGCGGCCCCTGTCGG
GCTGATCTTCACCTCGGCCGTGTTCGAAGGCTTTGCCGAGGACAAGGCCACCATCAAGGCGGCGATGGATGCGGTGCAGA
ATCACCGCGAGACCGTGCAGCCGATCCGCGAAAAGACCGGCGGCTCGACCTTCAAGAATCCCGAAGGCACGTCGGCCTGG
AAGGAGATCGACAAGGCGGGCTGCCGTGGCCTGATGATCGGCGGCGCGCAGATGTCGCCGATGCACTGCAATTTCATGAT
CAACACCGGCACTGCGACCGGCTACGACCTTGAATATCTCGGCGAGACGGTGCGCGCCCGCGTGCTCGAACATTCGGGCA
TCCGGCTGCAGTGGGAGATCAAGCGCATCGGCAATTTCCGGCCCGGACATGCCGTTCAGGAGTTTTTGGGTCAGCTTCTC
TGA

Upstream 100 bases:

>100_bases
TTCGCGGCCTGGCCAAGCCCGGCGACTTCGTCGTCTTCCTCGGCGCCGGCAACATCACCCAATGGGCCTATGCTCTGCCA
AAGGAGCTTGCCGCCTCATG

Downstream 100 bases:

>100_bases
CCTGTGCTGAAGTTCATGTGATGCATGAACTTCAGCACCTTCCCAAAACGCGCAAAACCGTTGCTCCAGGGACTCAGCGG
CACGGTTTTCGCAGCCATTT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MHGQALIDRLGDRLAGLRGRLTPNAEMDKITWFRAGGLAEVFFQPADEEDLAAFLRAVPEEIPLTIVGVGSNLLVRDGGI
PGFVIRLSAKGFGEAEIVSPIRIKAGAATPDKRVAALALEAGIGGFHFYHGIPGAIGGALRMNAGANGVETRERVVEVRA
LDRKGNVQTMSNAEMGYAYRHSAAPVGLIFTSAVFEGFAEDKATIKAAMDAVQNHRETVQPIREKTGGSTFKNPEGTSAW
KEIDKAGCRGLMIGGAQMSPMHCNFMINTGTATGYDLEYLGETVRARVLEHSGIRLQWEIKRIGNFRPGHAVQEFLGQLL

Sequences:

>Translated_320_residues
MHGQALIDRLGDRLAGLRGRLTPNAEMDKITWFRAGGLAEVFFQPADEEDLAAFLRAVPEEIPLTIVGVGSNLLVRDGGI
PGFVIRLSAKGFGEAEIVSPIRIKAGAATPDKRVAALALEAGIGGFHFYHGIPGAIGGALRMNAGANGVETRERVVEVRA
LDRKGNVQTMSNAEMGYAYRHSAAPVGLIFTSAVFEGFAEDKATIKAAMDAVQNHRETVQPIREKTGGSTFKNPEGTSAW
KEIDKAGCRGLMIGGAQMSPMHCNFMINTGTATGYDLEYLGETVRARVLEHSGIRLQWEIKRIGNFRPGHAVQEFLGQLL
>Mature_320_residues
MHGQALIDRLGDRLAGLRGRLTPNAEMDKITWFRAGGLAEVFFQPADEEDLAAFLRAVPEEIPLTIVGVGSNLLVRDGGI
PGFVIRLSAKGFGEAEIVSPIRIKAGAATPDKRVAALALEAGIGGFHFYHGIPGAIGGALRMNAGANGVETRERVVEVRA
LDRKGNVQTMSNAEMGYAYRHSAAPVGLIFTSAVFEGFAEDKATIKAAMDAVQNHRETVQPIREKTGGSTFKNPEGTSAW
KEIDKAGCRGLMIGGAQMSPMHCNFMINTGTATGYDLEYLGETVRARVLEHSGIRLQWEIKRIGNFRPGHAVQEFLGQLL

Specific function: Cell wall formation

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURB_RHILO (Q98KB5)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_103113.1
- ProteinModelPortal:   Q98KB5
- SMR:   Q98KB5
- GeneID:   1225776
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll1552
- NMPDR:   fig|266835.1.peg.1218
- HOGENOM:   HBG686573
- OMA:   SKKHAGF
- ProtClustDB:   PRK13905
- BRENDA:   1.1.1.158
- GO:   GO:0005737
- HAMAP:   MF_00037
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094
- Gene3D:   G3DSA:3.30.465.10
- Gene3D:   G3DSA:3.30.43.10
- Gene3D:   G3DSA:3.90.78.10
- PANTHER:   PTHR21071
- TIGRFAMs:   TIGR00179

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C; SSF56176 FAD-binding_2; SSF56194 MurB_C

EC number: =1.1.1.158

Molecular weight: Translated: 34441; Mature: 34441

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS51387 FAD_PCMH

Important sites: ACT_SITE 180-180 ACT_SITE 229-229 ACT_SITE 299-299

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGQALIDRLGDRLAGLRGRLTPNAEMDKITWFRAGGLAEVFFQPADEEDLAAFLRAVPE
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCHHHHHHHHHHCHH
EIPLTIVGVGSNLLVRDGGIPGFVIRLSAKGFGEAEIVSPIRIKAGAATPDKRVAALALE
HCCEEEEECCCCEEEECCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCCCHHHHHHHHH
AGIGGFHFYHGIPGAIGGALRMNAGANGVETRERVVEVRALDRKGNVQTMSNAEMGYAYR
HCCCCCHHHCCCCHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEE
HSAAPVGLIFTSAVFEGFAEDKATIKAAMDAVQNHRETVQPIREKTGGSTFKNPEGTSAW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
KEIDKAGCRGLMIGGAQMSPMHCNFMINTGTATGYDLEYLGETVRARVLEHSGIRLQWEI
HHHHHHCCCEEEECCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEE
KRIGNFRPGHAVQEFLGQLL
EECCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MHGQALIDRLGDRLAGLRGRLTPNAEMDKITWFRAGGLAEVFFQPADEEDLAAFLRAVPE
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCHHHHHHHHHHCHH
EIPLTIVGVGSNLLVRDGGIPGFVIRLSAKGFGEAEIVSPIRIKAGAATPDKRVAALALE
HCCEEEEECCCCEEEECCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCCCHHHHHHHHH
AGIGGFHFYHGIPGAIGGALRMNAGANGVETRERVVEVRALDRKGNVQTMSNAEMGYAYR
HCCCCCHHHCCCCHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEE
HSAAPVGLIFTSAVFEGFAEDKATIKAAMDAVQNHRETVQPIREKTGGSTFKNPEGTSAW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
KEIDKAGCRGLMIGGAQMSPMHCNFMINTGTATGYDLEYLGETVRARVLEHSGIRLQWEI
HHHHHHCCCEEEECCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEE
KRIGNFRPGHAVQEFLGQLL
EECCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968