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The map label for this gene is gcd [H]

Identifier: 13471506

GI number: 13471506

Start: 1242569

End: 1244926

Strand: Reverse

Name: gcd [H]

Synonym: mll1500

Alternate gene names: 13471506

Gene position: 1244926-1242569 (Counterclockwise)

Preceding gene: 13471510

Following gene: 13471503

Centisome position: 17.69

GC content: 66.33

Gene sequence:

>2358_bases
ATGGCCGCGCGAGCGCGCAACAGTCGAAGGAGTATCATCTTGGCTGTCACCATCACCTCCTTCGTTCTCTTTCTCCTCGG
TCTGGCGCTTGGTGGCGGTGGCATCTGGCTGGCTTCGCTGGGGGGCAGTTGGTACTACATCGTCGTCGGCCTCGCCTTCC
TGATCGCCGCCTGGCTGCTCTACCGGCGCCGTTCCACGGCGCTCTGGCTCTATGCGGCGATTGTGCTCGGCACGCTGGCC
TGGGCGGTCTGGGAAATCGGCTTCGACTGGTGGGAGCTCGGCCCGCGCGGCGGCATCATCGTGCTGGTCGGGCTGTGGCT
GCTGACGCCGTGGGCAAGGCGGGGCCTTGCCGGGCCTGACGGGCGCGCGCCGCTGATCCTGGCCGTGCTGGCATCGCTGG
CGGTGGCCGGCTATTCGATGACCGCCGACCCGAAAGGCATTGACGGCGCGCTCGACACCGACAAGGTGATTCCCAAAGCC
AATCTGGGTAATGATGTGCCGGCTGGCGAGTGGCACTATTACGGACGCACGCAGTTTGGCCAACGCTATTCGCCGCTCGA
CCAGATCACGCCGGACAATGTCGCCAATCTGCAGCCGGCATGGACCTATCGCACCGGCGATGTGAAGGGGCCCGACGACA
TCGGCGAGACCACCTATCAGGTGACGCCGCTGAAGATCGGCGACACGCTCTACATCTGCACGCCGCATAATTTCGCCATC
GCGGTGGACGCCGCGACCGGAAAGGAAAAATGGCGCTACGATCCCAAGATCAAGCTCGACAAGGACCGCCAGCACCAGAC
CTGCCGCGGCGTGTCCTACTATGCCGATACCGCCATCGCCGCCGGCCAGCCCTGCGCGACCCGCATCTACCTGCCGACCT
CGGATGCGCGGCTGATCGCGCTCGACGCCGCCAGCGGTCAGGTCTGTCCGGCCTTCGCCGAGGGCGGCACGCTGAACCTT
CTGACCAACATGCCCTATCCGAAATCGGGCTACTACTATTCGACCTCGGCGCCGCTGATATCAGGCAGCAAGATCATCGT
CGGCGGCGCGGTCAACGACAACTATTCGACGCAGGAGCCGTCGGGGGTCATCCGCGCCTATGATGTCGGCACCGGCGCCC
TGGTGTGGAAGTGGGATTCCGGCAACCCGGACCAGACGACGCCGCTGGCGGCGGGCCAGACCTATACCGCCAACTCGCCC
AACATGTGGTCGACGCCGAGCGCCGACGAGAAGCTTGGGCTGCTCTATGTGCCACTCGGCAACCAGACGCCGGACCAGCT
CGGCGCCGGGCGTAGCGCCAATGTCGAGAAATTCTCCTCCTCGATCGCCGCGCTCGACCTCAACACCGGGCAGTTGCGCT
GGGTGCGGCAGACCGTGCACCATGACCTCTGGGACATGGACGTGCCGGCGCAGCCGAGCCTGATTGACATCACCAAGGCC
GACGGCACAGTGGTGCCGGCGCTGGTCGGGCCGACCAAGCAGGGCGACCTCTATGTGCTTGACCGGCGCACCGGCGAACC
GCTTGTTGCAGTCAAGGAAGTGCCGGCGCCCGGCGGCGCCGTCGAGGGCGATCACACGTCGCCGACGCAACCGGTGTCGG
ATCTCTCCTTCAGCCCGAAGCCGCTGACGGATGCCGACATGTGGGGCATCACCATGTTCGACCAGATGGCCTGCAGGATT
GCCTTCCACAAGCTGCGCTACGAAGGCCGTTACACGCCGCCGTCGGTGCAGGGATCGCTGATCTACCCCGGCAATTTCGG
AGTCTTCAACTGGGGCGGGGTGGCAGTCGATCCGGTGCGGCAGGTGATGTTCGGCATGCCGACCTATCTGGCGTTTACGT
CGAGACTCGTGCCCCGCGCGGACGTACCGCCGCCGGGCGATGACACCAAGGGCAGCGAGCAGGGGCTGAACCGCAACGAG
GGCGCGCCCTACGCAGTGGTGATGGGGCCGTTCCTGTCGCCTCTCGGCATTCCCTGCCAGGCGCCACCCTGGGGTTATGT
CGCGGGCGCGGATCTGCGGACCGGCACCATCGCCTACAAGCATCGCAACGGTACCGTCTACGATATGACGCCGCTGCCGC
TGCCGCTGAAGGTCGGCGTGCCGGGCATTGGCGGGCCGATCATCACTGCCGGCGGCGTCGCCTTCCTGGGTGCCGCGGTC
GACAACTATCTGCGCGCCTATGACCTGACGTCGGGCCGGCAACTCTGGCAGGCCAGGCTGCCCGCCGGCGGCCAGTCGAC
GCCGATGACCTATACGGTCGCCGACGGGCGCCAGTTCGTGGTCATCGTCGCCGGCGGCCACGGCTCGGTCGGCACCAAGC
CGGGGGATTATGTGATGGCTTACGCGCTGCCGAAATAG

Upstream 100 bases:

>100_bases
CAAGCAAGATGGATTGCCACCTTGGCGTGTGGGCAGCTTGACAGGCGGGGCAGGCGGGAGAAAGCTGTGCGCAGGGCAGG
AGCGATGCGCCGGGTTGCCC

Downstream 100 bases:

>100_bases
CCGTGTCGCGCTAGCCAGAAGCGGTCCTGGCGCAAGATCAGTTCACCGTTTCACGGAAACGGCGAACTGCTCTAGTCCCA
AGGGAAAGCGCTGCGCGCTT

Product: glucose dehydrogenase

Products: NA

Alternate protein names: Glucose dehydrogenase [pyrroloquinoline-quinone] [H]

Number of amino acids: Translated: 785; Mature: 784

Protein sequence:

>785_residues
MAARARNSRRSIILAVTITSFVLFLLGLALGGGGIWLASLGGSWYYIVVGLAFLIAAWLLYRRRSTALWLYAAIVLGTLA
WAVWEIGFDWWELGPRGGIIVLVGLWLLTPWARRGLAGPDGRAPLILAVLASLAVAGYSMTADPKGIDGALDTDKVIPKA
NLGNDVPAGEWHYYGRTQFGQRYSPLDQITPDNVANLQPAWTYRTGDVKGPDDIGETTYQVTPLKIGDTLYICTPHNFAI
AVDAATGKEKWRYDPKIKLDKDRQHQTCRGVSYYADTAIAAGQPCATRIYLPTSDARLIALDAASGQVCPAFAEGGTLNL
LTNMPYPKSGYYYSTSAPLISGSKIIVGGAVNDNYSTQEPSGVIRAYDVGTGALVWKWDSGNPDQTTPLAAGQTYTANSP
NMWSTPSADEKLGLLYVPLGNQTPDQLGAGRSANVEKFSSSIAALDLNTGQLRWVRQTVHHDLWDMDVPAQPSLIDITKA
DGTVVPALVGPTKQGDLYVLDRRTGEPLVAVKEVPAPGGAVEGDHTSPTQPVSDLSFSPKPLTDADMWGITMFDQMACRI
AFHKLRYEGRYTPPSVQGSLIYPGNFGVFNWGGVAVDPVRQVMFGMPTYLAFTSRLVPRADVPPPGDDTKGSEQGLNRNE
GAPYAVVMGPFLSPLGIPCQAPPWGYVAGADLRTGTIAYKHRNGTVYDMTPLPLPLKVGVPGIGGPIITAGGVAFLGAAV
DNYLRAYDLTSGRQLWQARLPAGGQSTPMTYTVADGRQFVVIVAGGHGSVGTKPGDYVMAYALPK

Sequences:

>Translated_785_residues
MAARARNSRRSIILAVTITSFVLFLLGLALGGGGIWLASLGGSWYYIVVGLAFLIAAWLLYRRRSTALWLYAAIVLGTLA
WAVWEIGFDWWELGPRGGIIVLVGLWLLTPWARRGLAGPDGRAPLILAVLASLAVAGYSMTADPKGIDGALDTDKVIPKA
NLGNDVPAGEWHYYGRTQFGQRYSPLDQITPDNVANLQPAWTYRTGDVKGPDDIGETTYQVTPLKIGDTLYICTPHNFAI
AVDAATGKEKWRYDPKIKLDKDRQHQTCRGVSYYADTAIAAGQPCATRIYLPTSDARLIALDAASGQVCPAFAEGGTLNL
LTNMPYPKSGYYYSTSAPLISGSKIIVGGAVNDNYSTQEPSGVIRAYDVGTGALVWKWDSGNPDQTTPLAAGQTYTANSP
NMWSTPSADEKLGLLYVPLGNQTPDQLGAGRSANVEKFSSSIAALDLNTGQLRWVRQTVHHDLWDMDVPAQPSLIDITKA
DGTVVPALVGPTKQGDLYVLDRRTGEPLVAVKEVPAPGGAVEGDHTSPTQPVSDLSFSPKPLTDADMWGITMFDQMACRI
AFHKLRYEGRYTPPSVQGSLIYPGNFGVFNWGGVAVDPVRQVMFGMPTYLAFTSRLVPRADVPPPGDDTKGSEQGLNRNE
GAPYAVVMGPFLSPLGIPCQAPPWGYVAGADLRTGTIAYKHRNGTVYDMTPLPLPLKVGVPGIGGPIITAGGVAFLGAAV
DNYLRAYDLTSGRQLWQARLPAGGQSTPMTYTVADGRQFVVIVAGGHGSVGTKPGDYVMAYALPK
>Mature_784_residues
AARARNSRRSIILAVTITSFVLFLLGLALGGGGIWLASLGGSWYYIVVGLAFLIAAWLLYRRRSTALWLYAAIVLGTLAW
AVWEIGFDWWELGPRGGIIVLVGLWLLTPWARRGLAGPDGRAPLILAVLASLAVAGYSMTADPKGIDGALDTDKVIPKAN
LGNDVPAGEWHYYGRTQFGQRYSPLDQITPDNVANLQPAWTYRTGDVKGPDDIGETTYQVTPLKIGDTLYICTPHNFAIA
VDAATGKEKWRYDPKIKLDKDRQHQTCRGVSYYADTAIAAGQPCATRIYLPTSDARLIALDAASGQVCPAFAEGGTLNLL
TNMPYPKSGYYYSTSAPLISGSKIIVGGAVNDNYSTQEPSGVIRAYDVGTGALVWKWDSGNPDQTTPLAAGQTYTANSPN
MWSTPSADEKLGLLYVPLGNQTPDQLGAGRSANVEKFSSSIAALDLNTGQLRWVRQTVHHDLWDMDVPAQPSLIDITKAD
GTVVPALVGPTKQGDLYVLDRRTGEPLVAVKEVPAPGGAVEGDHTSPTQPVSDLSFSPKPLTDADMWGITMFDQMACRIA
FHKLRYEGRYTPPSVQGSLIYPGNFGVFNWGGVAVDPVRQVMFGMPTYLAFTSRLVPRADVPPPGDDTKGSEQGLNRNEG
APYAVVMGPFLSPLGIPCQAPPWGYVAGADLRTGTIAYKHRNGTVYDMTPLPLPLKVGVPGIGGPIITAGGVAFLGAAVD
NYLRAYDLTSGRQLWQARLPAGGQSTPMTYTVADGRQFVVIVAGGHGSVGTKPGDYVMAYALPK

Specific function: GDH is probably involved in energy conservation rather than in sugar metabolism [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=799, Percent_Identity=50.6883604505632, Blast_Score=761, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017511
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.5.2 [H]

Molecular weight: Translated: 84085; Mature: 83953

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARARNSRRSIILAVTITSFVLFLLGLALGGGGIWLASLGGSWYYIVVGLAFLIAAWLL
CCCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
YRRRSTALWLYAAIVLGTLAWAVWEIGFDWWELGPRGGIIVLVGLWLLTPWARRGLAGPD
HHCCCCHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCEEEEEHHHHHCHHHHCCCCCCC
GRAPLILAVLASLAVAGYSMTADPKGIDGALDTDKVIPKANLGNDVPAGEWHYYGRTQFG
CCCHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCC
QRYSPLDQITPDNVANLQPAWTYRTGDVKGPDDIGETTYQVTPLKIGDTLYICTPHNFAI
CCCCCHHHCCCCCCCCCCCCEEEECCCCCCCHHCCCCEEEEEEEEECCEEEEECCCCEEE
AVDAATGKEKWRYDPKIKLDKDRQHQTCRGVSYYADTAIAAGQPCATRIYLPTSDARLIA
EEECCCCCHHCCCCCCEEECCCCCCHHHCCCHHHHCCHHCCCCCCEEEEEEECCCCEEEE
LDAASGQVCPAFAEGGTLNLLTNMPYPKSGYYYSTSAPLISGSKIIVGGAVNDNYSTQEP
EECCCCCCCCHHCCCCEEEEEECCCCCCCCEEEECCCCEECCCEEEEEECCCCCCCCCCC
SGVIRAYDVGTGALVWKWDSGNPDQTTPLAAGQTYTANSPNMWSTPSADEKLGLLYVPLG
CCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEECC
NQTPDQLGAGRSANVEKFSSSIAALDLNTGQLRWVRQTVHHDLWDMDVPAQPSLIDITKA
CCCHHHHCCCCCCCHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECC
DGTVVPALVGPTKQGDLYVLDRRTGEPLVAVKEVPAPGGAVEGDHTSPTQPVSDLSFSPK
CCEEEEEEECCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCC
PLTDADMWGITMFDQMACRIAFHKLRYEGRYTPPSVQGSLIYPGNFGVFNWGGVAVDPVR
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCEEECCCEEHHHHH
QVMFGMPTYLAFTSRLVPRADVPPPGDDTKGSEQGLNRNEGAPYAVVMGPFLSPLGIPCQ
HHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCEEEEECCCCCCCCCCCC
APPWGYVAGADLRTGTIAYKHRNGTVYDMTPLPLPLKVGVPGIGGPIITAGGVAFLGAAV
CCCCCEEECCCCEECEEEEEECCCEEEECCCCCEEEEECCCCCCCCEEECCHHHHHHHHH
DNYLRAYDLTSGRQLWQARLPAGGQSTPMTYTVADGRQFVVIVAGGHGSVGTKPGDYVMA
HHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCEEEE
YALPK
EECCC
>Mature Secondary Structure 
AARARNSRRSIILAVTITSFVLFLLGLALGGGGIWLASLGGSWYYIVVGLAFLIAAWLL
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
YRRRSTALWLYAAIVLGTLAWAVWEIGFDWWELGPRGGIIVLVGLWLLTPWARRGLAGPD
HHCCCCHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCEEEEEHHHHHCHHHHCCCCCCC
GRAPLILAVLASLAVAGYSMTADPKGIDGALDTDKVIPKANLGNDVPAGEWHYYGRTQFG
CCCHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCC
QRYSPLDQITPDNVANLQPAWTYRTGDVKGPDDIGETTYQVTPLKIGDTLYICTPHNFAI
CCCCCHHHCCCCCCCCCCCCEEEECCCCCCCHHCCCCEEEEEEEEECCEEEEECCCCEEE
AVDAATGKEKWRYDPKIKLDKDRQHQTCRGVSYYADTAIAAGQPCATRIYLPTSDARLIA
EEECCCCCHHCCCCCCEEECCCCCCHHHCCCHHHHCCHHCCCCCCEEEEEEECCCCEEEE
LDAASGQVCPAFAEGGTLNLLTNMPYPKSGYYYSTSAPLISGSKIIVGGAVNDNYSTQEP
EECCCCCCCCHHCCCCEEEEEECCCCCCCCEEEECCCCEECCCEEEEEECCCCCCCCCCC
SGVIRAYDVGTGALVWKWDSGNPDQTTPLAAGQTYTANSPNMWSTPSADEKLGLLYVPLG
CCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEECC
NQTPDQLGAGRSANVEKFSSSIAALDLNTGQLRWVRQTVHHDLWDMDVPAQPSLIDITKA
CCCHHHHCCCCCCCHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECC
DGTVVPALVGPTKQGDLYVLDRRTGEPLVAVKEVPAPGGAVEGDHTSPTQPVSDLSFSPK
CCEEEEEEECCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHCCCCCC
PLTDADMWGITMFDQMACRIAFHKLRYEGRYTPPSVQGSLIYPGNFGVFNWGGVAVDPVR
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCEEECCCEEHHHHH
QVMFGMPTYLAFTSRLVPRADVPPPGDDTKGSEQGLNRNEGAPYAVVMGPFLSPLGIPCQ
HHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCEEEEECCCCCCCCCCCC
APPWGYVAGADLRTGTIAYKHRNGTVYDMTPLPLPLKVGVPGIGGPIITAGGVAFLGAAV
CCCCCEEECCCCEECEEEEEECCCEEEECCCCCEEEEECCCCCCCCEEECCHHHHHHHHH
DNYLRAYDLTSGRQLWQARLPAGGQSTPMTYTVADGRQFVVIVAGGHGSVGTKPGDYVMA
HHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCEEEE
YALPK
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2228962; 8419307; 8202364; 9278503; 8509415; 8554505 [H]