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The map label for this gene is pdxJ

Identifier: 13471446

GI number: 13471446

Start: 1184868

End: 1185608

Strand: Reverse

Name: pdxJ

Synonym: mll1418

Alternate gene names: 13471446

Gene position: 1185608-1184868 (Counterclockwise)

Preceding gene: 13471447

Following gene: 13471445

Centisome position: 16.85

GC content: 64.1

Gene sequence:

>741_bases
ATGCCCGCAAAGCTTTCCGTCAACCTCAACGCCATCGCCATGCTGCGCAACCGGCGCGACCTGCCATGGCCCAGCGTCAC
CGGCATCGGCCGGCTTGCGCTTGCCGCCGGTGCGCATGGGCTGACCGTGCATCCGCGTCCCGACGAGCGTCACACGCGGC
ATTCCGACCTGCCCGAAATCCGGGCGCTGATCGACGATGAGTTCCCGCAGGCGGAATTCAATATCGAGGGCTACCCGAGC
GAGGATTTCCTGGCGCTTGTGGAAAAGCATCAGCCCGAACAGGTGACGCTGGTTCCCGATGATCCGGCGCAGGCAACCTC
CGACCATGGCTGGAACTTCGTCGCCGATGCGGCGTTGCTGACACCGATCGTCAGGCGCCTGAAGAAGGGCGGCTTCAGGG
TGTCGCTGTTTTCCGACGCCGATCCCGCCGGCATGACAGCCGCGCGAGACACCGGCGCCGACCGGATCGAGCTCTATACC
GGCCCTTATGGCAGCTACCATTCCGATTCCGCAAAAGCCGACAAAGAACTGGAAAGATTGGGGAAAACAGCCGACGCGGC
ATTCGCCGCCGGCCTCCAGGTCAATGCCGGGCACGATCTGACGGTGGGCAATCTGCCGGCCCTGGCCAAGCGCATTCCGG
CATTGGCCGAAGTGTCAATCGGACATGGGTTGACAGCCGACGCGTTGGAGTATGGCATGGCCGGCACGGTGGGGCGGTTT
CTCAGGGCCTGCGGTTGGTAA

Upstream 100 bases:

>100_bases
TTCCCATCAAAGGCGCTATAGATGCCCAATCCAGAGCGCGCTGCGGCTTAACGTGTGGCCATGGTGCGCCGCTAACCGCC
TGATTTCACGGACGCCAGAC

Downstream 100 bases:

>100_bases
GGGTAGAGTTTCGCCTTGCAGGTATGGCAGCCATAGCGTGCAACTGACATCGCATCGTAGCATGCGTGAAGCACCGCGCG
CTCGTCGGGGAGTGGTCTAT

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MPAKLSVNLNAIAMLRNRRDLPWPSVTGIGRLALAAGAHGLTVHPRPDERHTRHSDLPEIRALIDDEFPQAEFNIEGYPS
EDFLALVEKHQPEQVTLVPDDPAQATSDHGWNFVADAALLTPIVRRLKKGGFRVSLFSDADPAGMTAARDTGADRIELYT
GPYGSYHSDSAKADKELERLGKTADAAFAAGLQVNAGHDLTVGNLPALAKRIPALAEVSIGHGLTADALEYGMAGTVGRF
LRACGW

Sequences:

>Translated_246_residues
MPAKLSVNLNAIAMLRNRRDLPWPSVTGIGRLALAAGAHGLTVHPRPDERHTRHSDLPEIRALIDDEFPQAEFNIEGYPS
EDFLALVEKHQPEQVTLVPDDPAQATSDHGWNFVADAALLTPIVRRLKKGGFRVSLFSDADPAGMTAARDTGADRIELYT
GPYGSYHSDSAKADKELERLGKTADAAFAAGLQVNAGHDLTVGNLPALAKRIPALAEVSIGHGLTADALEYGMAGTVGRF
LRACGW
>Mature_245_residues
PAKLSVNLNAIAMLRNRRDLPWPSVTGIGRLALAAGAHGLTVHPRPDERHTRHSDLPEIRALIDDEFPQAEFNIEGYPSE
DFLALVEKHQPEQVTLVPDDPAQATSDHGWNFVADAALLTPIVRRLKKGGFRVSLFSDADPAGMTAARDTGADRIELYTG
PYGSYHSDSAKADKELERLGKTADAAFAAGLQVNAGHDLTVGNLPALAKRIPALAEVSIGHGLTADALEYGMAGTVGRFL
RACGW

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family

Homologues:

Organism=Escherichia coli, GI1788917, Length=238, Percent_Identity=35.7142857142857, Blast_Score=137, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXJ_RHILO (Q98KL6)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_103012.1
- ProteinModelPortal:   Q98KL6
- SMR:   Q98KL6
- GeneID:   1225675
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll1418
- NMPDR:   fig|266835.1.peg.1117
- HOGENOM:   HBG299314
- OMA:   AGHGLNY
- ProtClustDB:   PRK05265
- BRENDA:   2.6.99.2
- GO:   GO:0005737
- HAMAP:   MF_00279
- InterPro:   IPR013785
- InterPro:   IPR004569
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR00559

Pfam domain/function: PF03740 PdxJ; SSF63892 PyrdxlP_synth_PdxJ

EC number: =2.6.99.2

Molecular weight: Translated: 26420; Mature: 26289

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: ACT_SITE 44-44 ACT_SITE 76-76 ACT_SITE 198-198 BINDING 8-8 BINDING 19-19 BINDING 46-46 BINDING 51-51 BINDING 106-106 BINDING 199-199

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAKLSVNLNAIAMLRNRRDLPWPSVTGIGRLALAAGAHGLTVHPRPDERHTRHSDLPEI
CCCEEECCHHHHEEECCCCCCCCCCCCCHHHHHHHCCCCCCEECCCCCCCCCCCCCCHHH
RALIDDEFPQAEFNIEGYPSEDFLALVEKHQPEQVTLVPDDPAQATSDHGWNFVADAALL
HHHHCCCCCCCEECCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHH
TPIVRRLKKGGFRVSLFSDADPAGMTAARDTGADRIELYTGPYGSYHSDSAKADKELERL
HHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
GKTADAAFAAGLQVNAGHDLTVGNLPALAKRIPALAEVSIGHGLTADALEYGMAGTVGRF
CCHHHHHHHCCEEECCCCCCCCCCHHHHHHHCCHHHEECCCCCCCHHHHHHCCHHHHHHH
LRACGW
HHHHCC
>Mature Secondary Structure 
PAKLSVNLNAIAMLRNRRDLPWPSVTGIGRLALAAGAHGLTVHPRPDERHTRHSDLPEI
CCEEECCHHHHEEECCCCCCCCCCCCCHHHHHHHCCCCCCEECCCCCCCCCCCCCCHHH
RALIDDEFPQAEFNIEGYPSEDFLALVEKHQPEQVTLVPDDPAQATSDHGWNFVADAALL
HHHHCCCCCCCEECCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHH
TPIVRRLKKGGFRVSLFSDADPAGMTAARDTGADRIELYTGPYGSYHSDSAKADKELERL
HHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
GKTADAAFAAGLQVNAGHDLTVGNLPALAKRIPALAEVSIGHGLTADALEYGMAGTVGRF
CCHHHHHHHCCEEECCCCCCCCCCHHHHHHHCCHHHEECCCCCCCHHHHHHCCHHHHHHH
LRACGW
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968