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The map label for this gene is lolC [H]

Identifier: 13471386

GI number: 13471386

Start: 1124237

End: 1125523

Strand: Reverse

Name: lolC [H]

Synonym: mll1342

Alternate gene names: 13471386

Gene position: 1125523-1124237 (Counterclockwise)

Preceding gene: 13471387

Following gene: 13471385

Centisome position: 16.0

GC content: 62.94

Gene sequence:

>1287_bases
ATGAGCGAGGCGGCGGCGGCAAGATCGGCGGGCGCCGGCCCGTTCTCCTTCTTCGAGCGCACGGTTGCCTGGCGCTATTT
GCGCTCGCGGCGCAAGGAGACGGTGATCTCGGTCATCGCCTCGATCTCTTTCCTCGGCATCATGCTGGGGGTGGCGACGC
TGATCGTCGTCATGGCCGTGATGAACGGGTTCCGCGCCGAACTTTTGACGCGCATCCTTGGCGTCAACGGCCATCTGATC
GTGCAGCCGCTCGATTCGCCGCTTGAGGACTACGCCCAGGTCGCCGGCCGCATCAACGGCGTGCCCGGCGTCAAATACGC
CATTCCGCTGATCGACGGCCAAGTGCTGGCGCAAGGCAATGTCGGCGGCGGCACCGGCGCGCTGGTGCGCGGTATCAGGG
GCGAAGATCTCGGCAAGATCGCCATCGTCGCCAACAACATCAAGCAGGGTTCGCTCGCCAGTTTCGATTCGGGCGAGGGC
GTCGCCATCGGCAAGCGCATGGCGCAGAATCTCGGCCTGACGCTCGGCGACACCATCACGCTCATCTCGCCCGATGGCGA
CGTGACGCCGATCGGCACGACGCCGCGCATGAAAGGCTACAAGATCGCGGCGATCTTCGAAGTCGGTATGTCGGAGTATG
ACACGTCCATCGTCTACATGCCGTTCTCCGAAGCGCAGCTCTATTTCAACATGGATGGCCGCGCGCAGACGATCGAAATC
TATGTCGACAATCCCGACAATGTCGACGCGCTGAAACCGAAGGTGGAAGAGGCGGCGCAGCGGCCGATCGACATGGTCGA
CTGGCGCCAGCGTAACGAGACGTTCTTTTCCGCCCTGCAGGTCGAGCGCAACGTCATGTTCATGATCCTGACGCTGATCG
TGCTGGTGGCGGCGCTCAACATCATTTCGGGACTGATCATGCTGGTGAAGGACAAGGGGCACGACATCGCCATCCTGCGC
ACCATGGGCGCCTCGCGCGGCGCCATCCTGCGCATCTTCCTGATGACGGGGGCGGCGATCGGCGTCACCGGCACGCTCGC
CGGCGTGCTGCTCGGCGTCGTCATCTGCACCAACATAGAATCGATCCGCCAGTTCTTCTCCTGGATGACCGGCAAGGTGC
TGTTCAATCCGGAGCTCTATTTCCTCAGCCAGCTGCCGGCGAAGATGGATCCGCGCGAGACGACCTATGTCATCATCATG
GCGCTTGGGCTGTCCTTCCTGGCAACGGTGTTTCCGGCATGGCGGGCGGCTCGCCTCGATCCGGTCGAAGCCTTGAGGTA
CGAGTAG

Upstream 100 bases:

>100_bases
GCGGCGTGGCCGCCGGCGAGGTCGAGATCAAGAATCGCAGGACCGGCGAACGCGAAACGCTGCCCATCGCCGACGCGAAA
AAACGCTTTGGTGTCGCCGC

Downstream 100 bases:

>100_bases
TGGCCGAGGTCATTATCGAGCTGAAGAGCGTCGAGCGGCACTATGTCCAAGGGCCGCGCAAGCTCACTATTTTGAACGGC
GCCGATTTCTCGCTGAAGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSEAAAARSAGAGPFSFFERTVAWRYLRSRRKETVISVIASISFLGIMLGVATLIVVMAVMNGFRAELLTRILGVNGHLI
VQPLDSPLEDYAQVAGRINGVPGVKYAIPLIDGQVLAQGNVGGGTGALVRGIRGEDLGKIAIVANNIKQGSLASFDSGEG
VAIGKRMAQNLGLTLGDTITLISPDGDVTPIGTTPRMKGYKIAAIFEVGMSEYDTSIVYMPFSEAQLYFNMDGRAQTIEI
YVDNPDNVDALKPKVEEAAQRPIDMVDWRQRNETFFSALQVERNVMFMILTLIVLVAALNIISGLIMLVKDKGHDIAILR
TMGASRGAILRIFLMTGAAIGVTGTLAGVLLGVVICTNIESIRQFFSWMTGKVLFNPELYFLSQLPAKMDPRETTYVIIM
ALGLSFLATVFPAWRAARLDPVEALRYE

Sequences:

>Translated_428_residues
MSEAAAARSAGAGPFSFFERTVAWRYLRSRRKETVISVIASISFLGIMLGVATLIVVMAVMNGFRAELLTRILGVNGHLI
VQPLDSPLEDYAQVAGRINGVPGVKYAIPLIDGQVLAQGNVGGGTGALVRGIRGEDLGKIAIVANNIKQGSLASFDSGEG
VAIGKRMAQNLGLTLGDTITLISPDGDVTPIGTTPRMKGYKIAAIFEVGMSEYDTSIVYMPFSEAQLYFNMDGRAQTIEI
YVDNPDNVDALKPKVEEAAQRPIDMVDWRQRNETFFSALQVERNVMFMILTLIVLVAALNIISGLIMLVKDKGHDIAILR
TMGASRGAILRIFLMTGAAIGVTGTLAGVLLGVVICTNIESIRQFFSWMTGKVLFNPELYFLSQLPAKMDPRETTYVIIM
ALGLSFLATVFPAWRAARLDPVEALRYE
>Mature_427_residues
SEAAAARSAGAGPFSFFERTVAWRYLRSRRKETVISVIASISFLGIMLGVATLIVVMAVMNGFRAELLTRILGVNGHLIV
QPLDSPLEDYAQVAGRINGVPGVKYAIPLIDGQVLAQGNVGGGTGALVRGIRGEDLGKIAIVANNIKQGSLASFDSGEGV
AIGKRMAQNLGLTLGDTITLISPDGDVTPIGTTPRMKGYKIAAIFEVGMSEYDTSIVYMPFSEAQLYFNMDGRAQTIEIY
VDNPDNVDALKPKVEEAAQRPIDMVDWRQRNETFFSALQVERNVMFMILTLIVLVAALNIISGLIMLVKDKGHDIAILRT
MGASRGAILRIFLMTGAAIGVTGTLAGVLLGVVICTNIESIRQFFSWMTGKVLFNPELYFLSQLPAKMDPRETTYVIIMA
LGLSFLATVFPAWRAARLDPVEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=403, Percent_Identity=30.7692307692308, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1787360, Length=421, Percent_Identity=29.6912114014252, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46374; Mature: 46243

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAAAARSAGAGPFSFFERTVAWRYLRSRRKETVISVIASISFLGIMLGVATLIVVMAV
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNGFRAELLTRILGVNGHLIVQPLDSPLEDYAQVAGRINGVPGVKYAIPLIDGQVLAQGN
HCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEECC
VGGGTGALVRGIRGEDLGKIAIVANNIKQGSLASFDSGEGVAIGKRMAQNLGLTLGDTIT
CCCCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCEECCEEE
LISPDGDVTPIGTTPRMKGYKIAAIFEVGMSEYDTSIVYMPFSEAQLYFNMDGRAQTIEI
EECCCCCEECCCCCCCCCCEEEEEEEECCHHHCCCEEEEEECCCCEEEEEECCCEEEEEE
YVDNPDNVDALKPKVEEAAQRPIDMVDWRQRNETFFSALQVERNVMFMILTLIVLVAALN
EECCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IISGLIMLVKDKGHDIAILRTMGASRGAILRIFLMTGAAIGVTGTLAGVLLGVVICTNIE
HHHHHHEEEECCCCCEEEEEECCCCCCHHEEHHHHHCCHHHHHHHHHHHHHHHHHHCCHH
SIRQFFSWMTGKVLFNPELYFLSQLPAKMDPRETTYVIIMALGLSFLATVFPAWRAARLD
HHHHHHHHHCCCEEECCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
PVEALRYE
HHHHHCCC
>Mature Secondary Structure 
SEAAAARSAGAGPFSFFERTVAWRYLRSRRKETVISVIASISFLGIMLGVATLIVVMAV
CCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNGFRAELLTRILGVNGHLIVQPLDSPLEDYAQVAGRINGVPGVKYAIPLIDGQVLAQGN
HCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEECC
VGGGTGALVRGIRGEDLGKIAIVANNIKQGSLASFDSGEGVAIGKRMAQNLGLTLGDTIT
CCCCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCEECCEEE
LISPDGDVTPIGTTPRMKGYKIAAIFEVGMSEYDTSIVYMPFSEAQLYFNMDGRAQTIEI
EECCCCCEECCCCCCCCCCEEEEEEEECCHHHCCCEEEEEECCCCEEEEEECCCEEEEEE
YVDNPDNVDALKPKVEEAAQRPIDMVDWRQRNETFFSALQVERNVMFMILTLIVLVAALN
EECCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IISGLIMLVKDKGHDIAILRTMGASRGAILRIFLMTGAAIGVTGTLAGVLLGVVICTNIE
HHHHHHEEEECCCCCEEEEEECCCCCCHHEEHHHHHCCHHHHHHHHHHHHHHHHHHCCHH
SIRQFFSWMTGKVLFNPELYFLSQLPAKMDPRETTYVIIMALGLSFLATVFPAWRAARLD
HHHHHHHHHCCCEEECCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
PVEALRYE
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]