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The map label for this gene is gsiD [H]

Identifier: 13471268

GI number: 13471268

Start: 1000747

End: 1001616

Strand: Direct

Name: gsiD [H]

Synonym: mlr1189

Alternate gene names: 13471268

Gene position: 1000747-1001616 (Clockwise)

Preceding gene: 13471267

Following gene: 13471269

Centisome position: 14.22

GC content: 64.71

Gene sequence:

>870_bases
ATGACCCTGCACATCGACATCCCTGAAGAGACGTTGAGTGGCATTCTGGCCAAGGCGTTCCGGAACACGGCTTTCGTCAC
CGGCTTCGTCATCACCGTGCTGATCCTGGCGATGGCTCTCGTGTCCTATCCCTGGACGCCCTACGATGTGACGAAGCTGG
TCATAGCCGACAAGACGCAAGGCCCCTCGCTGGCACATTGGTTCGGGACCGACCATTTCGGCCGCGACATCCTGTCGATG
ATCATGGTCGGCGCCCGCAATTCGATCGCCGTGGCGCTGGTCGCGGTCGGCATCGGCATGGGCGTCGGCGTGCCGCTCGG
CGCTTTTGCGGCCGCGCGCGGCGGCCTCGTCGACGAGGCGCTGATGCGCGTCAACGACCTCGTCTTTGCTTTCCCCGCGC
TGCTGTCGGCCATCATGATTACCGCCATCTTCGGGCCGGGCGCCGTCAACGCCATCATCGCCATCGGCATCTTCAACATC
CCGGTCTTTGCCCGCGTCGCCCGCGCCGGAGCGCTGGCCATCTGGCCGCGCGAATTCATCCTGGCCGCGCGCGCCGCAGG
AAAAAGCAGCACGCAGATATCGATCGAACATGTGCTGCCCAACATCGCAACGCTGCTCCTGGTGCAAGGCACCATACAGT
TCGCGCTGGGCATCCTCGCCGAAGCCGGGCTTTCCTATCTCGGCCTCGGCGCGCAGCCGCCAATGCCGAGTTGGGGCCGC
ATGCTGTTCGACGCACAGACGCGCATGGTGGTGGCGCCATGGATGGCGATCTTTCCCGGCATGGCGATCGTCATCACCGT
GCTCGGGCTCAATCTCCTGGGCGACGGCATCGCCGACATTCTCGACCCGAAATCGCGGCGGCAGCGATGA

Upstream 100 bases:

>100_bases
TTGAAAGCGTCGTGATGTTGCTGGTCGCCGCCGTCATTGCCGTCAACCTCGTCGTCGACCTTTCCTATGCGGTGGTCGAT
CCCCGCCTGAGAAGCCGGCA

Downstream 100 bases:

>100_bases
GCTTGCTGGAAATCGACAACCTGTCGCTGACCATCGGCGACACGCAGATCCTGAAGGACATGGAACTCTCCGTCGCGCCC
GGCGAGGTGATGGGGCTGGT

Product: permease protein of oligopeptide ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MTLHIDIPEETLSGILAKAFRNTAFVTGFVITVLILAMALVSYPWTPYDVTKLVIADKTQGPSLAHWFGTDHFGRDILSM
IMVGARNSIAVALVAVGIGMGVGVPLGAFAAARGGLVDEALMRVNDLVFAFPALLSAIMITAIFGPGAVNAIIAIGIFNI
PVFARVARAGALAIWPREFILAARAAGKSSTQISIEHVLPNIATLLLVQGTIQFALGILAEAGLSYLGLGAQPPMPSWGR
MLFDAQTRMVVAPWMAIFPGMAIVITVLGLNLLGDGIADILDPKSRRQR

Sequences:

>Translated_289_residues
MTLHIDIPEETLSGILAKAFRNTAFVTGFVITVLILAMALVSYPWTPYDVTKLVIADKTQGPSLAHWFGTDHFGRDILSM
IMVGARNSIAVALVAVGIGMGVGVPLGAFAAARGGLVDEALMRVNDLVFAFPALLSAIMITAIFGPGAVNAIIAIGIFNI
PVFARVARAGALAIWPREFILAARAAGKSSTQISIEHVLPNIATLLLVQGTIQFALGILAEAGLSYLGLGAQPPMPSWGR
MLFDAQTRMVVAPWMAIFPGMAIVITVLGLNLLGDGIADILDPKSRRQR
>Mature_288_residues
TLHIDIPEETLSGILAKAFRNTAFVTGFVITVLILAMALVSYPWTPYDVTKLVIADKTQGPSLAHWFGTDHFGRDILSMI
MVGARNSIAVALVAVGIGMGVGVPLGAFAAARGGLVDEALMRVNDLVFAFPALLSAIMITAIFGPGAVNAIIAIGIFNIP
VFARVARAGALAIWPREFILAARAAGKSSTQISIEHVLPNIATLLLVQGTIQFALGILAEAGLSYLGLGAQPPMPSWGRM
LFDAQTRMVVAPWMAIFPGMAIVITVLGLNLLGDGIADILDPKSRRQR

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=267, Percent_Identity=43.0711610486891, Blast_Score=217, Evalue=8e-58,
Organism=Escherichia coli, GI1787760, Length=261, Percent_Identity=38.6973180076628, Blast_Score=177, Evalue=5e-46,
Organism=Escherichia coli, GI1789964, Length=228, Percent_Identity=43.421052631579, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789889, Length=243, Percent_Identity=34.5679012345679, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1787498, Length=269, Percent_Identity=34.5724907063197, Blast_Score=144, Evalue=9e-36,
Organism=Escherichia coli, GI1787549, Length=276, Percent_Identity=32.9710144927536, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788505, Length=226, Percent_Identity=28.7610619469027, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30540; Mature: 30409

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLHIDIPEETLSGILAKAFRNTAFVTGFVITVLILAMALVSYPWTPYDVTKLVIADKTQ
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEEECCCC
GPSLAHWFGTDHFGRDILSMIMVGARNSIAVALVAVGIGMGVGVPLGAFAAARGGLVDEA
CCCHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHH
LMRVNDLVFAFPALLSAIMITAIFGPGAVNAIIAIGIFNIPVFARVARAGALAIWPREFI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHH
LAARAAGKSSTQISIEHVLPNIATLLLVQGTIQFALGILAEAGLSYLGLGAQPPMPSWGR
HHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCHHHH
MLFDAQTRMVVAPWMAIFPGMAIVITVLGLNLLGDGIADILDPKSRRQR
HHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHCCCHHHCCC
>Mature Secondary Structure 
TLHIDIPEETLSGILAKAFRNTAFVTGFVITVLILAMALVSYPWTPYDVTKLVIADKTQ
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEEECCCC
GPSLAHWFGTDHFGRDILSMIMVGARNSIAVALVAVGIGMGVGVPLGAFAAARGGLVDEA
CCCHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHH
LMRVNDLVFAFPALLSAIMITAIFGPGAVNAIIAIGIFNIPVFARVARAGALAIWPREFI
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHH
LAARAAGKSSTQISIEHVLPNIATLLLVQGTIQFALGILAEAGLSYLGLGAQPPMPSWGR
HHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCHHHH
MLFDAQTRMVVAPWMAIFPGMAIVITVLGLNLLGDGIADILDPKSRRQR
HHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]