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The map label for this gene is qor [C]

Identifier: 13471258

GI number: 13471258

Start: 990254

End: 991282

Strand: Direct

Name: qor [C]

Synonym: mlr1178

Alternate gene names: 13471258

Gene position: 990254-991282 (Clockwise)

Preceding gene: 13471257

Following gene: 13471259

Centisome position: 14.07

GC content: 65.99

Gene sequence:

>1029_bases
ATGCGCGCACTGCAACTTATCGAGGACCGCCGTCTTGAAACGGTGGACCTGCCGCCTCCCCCGCCACCCGCGCTCGGCGA
AGTCACGCTGCGCATCAGGGCGGTGGCGCTGAACCACATCGACGTCTGGGGCTGGCGCGGCATGGCCTTCGCCAAGCGCA
AGCTGCCGCTGGTCGTCGGCGCCGAAGCCTCCGGCGAGGTCGAGGCGGTCGGCCCCGGCGTGTCCAGCCTGCTGCCCGGA
CAATTGGTGTCGATCTATGGCGCGCGCACCTGCGGCCTTTGCCGTGCCTGCCGCGAAGGCCGCGACAATCTTTGCGAACA
TGTTTCCGGGGTCCACGGCTTCCACCTCGACGGGTTTGCGCAGGAGAAGATCAACCTGCCGGCGCGCCTGTTGGTCCCCG
CCCCGCCCGGCGTGAGCGACATCGGCGCCGCGGTGGCCCCCGTCACCTTCGGCACGGTCGAGCACATGCTGTTCGACAAC
GCCAGGCTTCAGCCGGGCGAAACCATCCTCGTCCATGCCGGCGGCTCCGGCATTGGCTCGGCGGCGATCCAGCTGGCCAA
GCGGATGGGCTGCACCATTATCACCACCGTCGGTTCCAACGACAAGATCGACAAGGCCAAGGCGCTCGGCGCCGACCACG
TCATCAACTACCGCGAAGACCGCTTCGAAGGCGTCGTGCGCAAGCTAACCAAGAAGAAGGGCGTCGACGTCGTCTTCGAA
CATGTCGGCGCCGACACCTTTGCCGGCTCGATGCTGTGCCTGAAGCGCGGCGGCCGCCTAGTGACCTGCGGCTCGACATC
AGGCGTGTCGACGCAAATCAACCTGATGCAGCTCTTCCAGCAGCAATTGAAGCTGCTCGGCTCCTTCGGCTGCCGCATGG
AGAACATGGCCAACGCCATGCAGAAAATGGCGGCGGGACAGGTCGCGCCGGTCATCGACACCGAAGTCGGCTTCGACGAT
ATCGACGCAGCGCTAAAGCGCATGGAAGGCCGCGACGTCTTCGGCAAGATCATCCTGCGCGTCGCCTGA

Upstream 100 bases:

>100_bases
TCGAACTCCTTCGGCTTCGGCGGCCAGAACACTTGCCTTGTCATGGCGCGGGAACCGGTCTAAGCGAGCCACTTCCGCTC
GAACAGAACCGACAGGCCTT

Downstream 100 bases:

>100_bases
GGCCTTGACTCCGGTGCTCAAGAAGTTTCGCCGCGATCTCAGGTTTCGCTATGGCAGGCAGCTGCGCCAGCTGAACTACT
GGCTGGTTGCGCGGGCGGCG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Acryloyl-CoA reductase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MRALQLIEDRRLETVDLPPPPPPALGEVTLRIRAVALNHIDVWGWRGMAFAKRKLPLVVGAEASGEVEAVGPGVSSLLPG
QLVSIYGARTCGLCRACREGRDNLCEHVSGVHGFHLDGFAQEKINLPARLLVPAPPGVSDIGAAVAPVTFGTVEHMLFDN
ARLQPGETILVHAGGSGIGSAAIQLAKRMGCTIITTVGSNDKIDKAKALGADHVINYREDRFEGVVRKLTKKKGVDVVFE
HVGADTFAGSMLCLKRGGRLVTCGSTSGVSTQINLMQLFQQQLKLLGSFGCRMENMANAMQKMAAGQVAPVIDTEVGFDD
IDAALKRMEGRDVFGKIILRVA

Sequences:

>Translated_342_residues
MRALQLIEDRRLETVDLPPPPPPALGEVTLRIRAVALNHIDVWGWRGMAFAKRKLPLVVGAEASGEVEAVGPGVSSLLPG
QLVSIYGARTCGLCRACREGRDNLCEHVSGVHGFHLDGFAQEKINLPARLLVPAPPGVSDIGAAVAPVTFGTVEHMLFDN
ARLQPGETILVHAGGSGIGSAAIQLAKRMGCTIITTVGSNDKIDKAKALGADHVINYREDRFEGVVRKLTKKKGVDVVFE
HVGADTFAGSMLCLKRGGRLVTCGSTSGVSTQINLMQLFQQQLKLLGSFGCRMENMANAMQKMAAGQVAPVIDTEVGFDD
IDAALKRMEGRDVFGKIILRVA
>Mature_342_residues
MRALQLIEDRRLETVDLPPPPPPALGEVTLRIRAVALNHIDVWGWRGMAFAKRKLPLVVGAEASGEVEAVGPGVSSLLPG
QLVSIYGARTCGLCRACREGRDNLCEHVSGVHGFHLDGFAQEKINLPARLLVPAPPGVSDIGAAVAPVTFGTVEHMLFDN
ARLQPGETILVHAGGSGIGSAAIQLAKRMGCTIITTVGSNDKIDKAKALGADHVINYREDRFEGVVRKLTKKKGVDVVFE
HVGADTFAGSMLCLKRGGRLVTCGSTSGVSTQINLMQLFQQQLKLLGSFGCRMENMANAMQKMAAGQVAPVIDTEVGFDD
IDAALKRMEGRDVFGKIILRVA

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the acryloyl- CoA dependent NADPH oxidation and formation of propionyl-CoA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=335, Percent_Identity=28.6567164179104, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI22538444, Length=335, Percent_Identity=28.6567164179104, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI18379349, Length=337, Percent_Identity=26.7062314540059, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI194239674, Length=349, Percent_Identity=24.3553008595989, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI13236495, Length=349, Percent_Identity=24.3553008595989, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI24308257, Length=349, Percent_Identity=24.6418338108883, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI41872631, Length=212, Percent_Identity=28.7735849056604, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4501929, Length=310, Percent_Identity=29.3548387096774, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI28557745, Length=258, Percent_Identity=29.4573643410853, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI156627571, Length=337, Percent_Identity=27.893175074184, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI197927207, Length=190, Percent_Identity=27.3684210526316, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI67078404, Length=267, Percent_Identity=28.0898876404494, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI67078406, Length=240, Percent_Identity=29.1666666666667, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI226059159, Length=191, Percent_Identity=27.7486910994764, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI226059133, Length=191, Percent_Identity=27.7486910994764, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1790485, Length=270, Percent_Identity=32.2222222222222, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790045, Length=352, Percent_Identity=29.2613636363636, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788073, Length=268, Percent_Identity=30.2238805970149, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87081918, Length=316, Percent_Identity=26.5822784810127, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787863, Length=222, Percent_Identity=31.5315315315315, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI226510992, Length=289, Percent_Identity=25.9515570934256, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786518, Length=337, Percent_Identity=25.8160237388724, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790718, Length=283, Percent_Identity=26.8551236749117, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=343, Percent_Identity=25.6559766763848, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71988145, Length=178, Percent_Identity=29.7752808988764, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=263, Percent_Identity=28.1368821292776, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562584, Length=324, Percent_Identity=24.6913580246914, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6319621, Length=345, Percent_Identity=24.9275362318841, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6324486, Length=332, Percent_Identity=25.3012048192771, Blast_Score=93, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6322619, Length=330, Percent_Identity=28.4848484848485, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319955, Length=330, Percent_Identity=28.1818181818182, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323961, Length=345, Percent_Identity=24.6376811594203, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319520, Length=271, Percent_Identity=27.3062730627306, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=332, Percent_Identity=22.5903614457831, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319258, Length=277, Percent_Identity=27.0758122743682, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI19920632, Length=226, Percent_Identity=27.8761061946903, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI221330659, Length=226, Percent_Identity=27.8761061946903, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24581345, Length=225, Percent_Identity=27.5555555555556, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.3.1.84 [H]

Molecular weight: Translated: 36481; Mature: 36481

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALQLIEDRRLETVDLPPPPPPALGEVTLRIRAVALNHIDVWGWRGMAFAKRKLPLVVG
CCHHHHHHHCCCCEECCCCCCCCCCCCEEEEEEEEEECCEEECCCCCHHHHHHCCCEEEE
AEASGEVEAVGPGVSSLLPGQLVSIYGARTCGLCRACREGRDNLCEHVSGVHGFHLDGFA
CCCCCCEEEECCCHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
QEKINLPARLLVPAPPGVSDIGAAVAPVTFGTVEHMLFDNARLQPGETILVHAGGSGIGS
HHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHH
AAIQLAKRMGCTIITTVGSNDKIDKAKALGADHVINYREDRFEGVVRKLTKKKGVDVVFE
HHHHHHHHCCCEEEEECCCCCCCHHHHHCCCHHHHCCHHHHHHHHHHHHHHHCCHHHHHH
HVGADTFAGSMLCLKRGGRLVTCGSTSGVSTQINLMQLFQQQLKLLGSFGCRMENMANAM
HHCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QKMAAGQVAPVIDTEVGFDDIDAALKRMEGRDVFGKIILRVA
HHHHCCCCCCEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure
MRALQLIEDRRLETVDLPPPPPPALGEVTLRIRAVALNHIDVWGWRGMAFAKRKLPLVVG
CCHHHHHHHCCCCEECCCCCCCCCCCCEEEEEEEEEECCEEECCCCCHHHHHHCCCEEEE
AEASGEVEAVGPGVSSLLPGQLVSIYGARTCGLCRACREGRDNLCEHVSGVHGFHLDGFA
CCCCCCEEEECCCHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
QEKINLPARLLVPAPPGVSDIGAAVAPVTFGTVEHMLFDNARLQPGETILVHAGGSGIGS
HHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHH
AAIQLAKRMGCTIITTVGSNDKIDKAKALGADHVINYREDRFEGVVRKLTKKKGVDVVFE
HHHHHHHHCCCEEEEECCCCCCCHHHHHCCCHHHHCCHHHHHHHHHHHHHHHCCHHHHHH
HVGADTFAGSMLCLKRGGRLVTCGSTSGVSTQINLMQLFQQQLKLLGSFGCRMENMANAM
HHCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QKMAAGQVAPVIDTEVGFDDIDAALKRMEGRDVFGKIILRVA
HHHHCCCCCCEEECCCCHHHHHHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA