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The map label for this gene is cutL [H]

Identifier: 13471217

GI number: 13471217

Start: 943634

End: 945982

Strand: Reverse

Name: cutL [H]

Synonym: mll1128

Alternate gene names: 13471217

Gene position: 945982-943634 (Counterclockwise)

Preceding gene: 13471218

Following gene: 13471216

Centisome position: 13.44

GC content: 63.9

Gene sequence:

>2349_bases
ATGGGCATTGAAGGTGTTGGCGCTCGGGTCGCGCGCAAGGAAGACAAAAGATTCATCACCGGCGCCGGCCGCTATGTCGA
CGACATGGTGGTTCCCGGCATGAAGCATGCCGCCTTCGTGCGCAGCCCGCACGCGCATGCGCAGATCAAGAAGATCGACG
TCAGACGAGCACAAGCGATGCCCGGCGTCATCGGCGTGCTGACCGGCAAGGAGCTCAAGGCCGACGGCATCGGCAATTTG
ATCTGCGGCTGGATGATCCATTCCAAGGACGGTTCGCCGATGAAGATGGGCGCCTGGTCGCCGCTGGCTGTCGACAAGGT
CCGCTATGTCGGTGACGCCGTCGTCGTCGTCGTGGCCGAGACCAAGGGGCAGGCCCGCGATGCGGCCGAGGCGGTCGAGA
TCACATACAAGGAATTGAAGGCCGTCGTCGAAGCCACCAAGGCGCTCGAAAAGGGCGCGCCGCAGATCCATGCCGAGGCC
GAGAACAATCTGATCTTCGATTGGGAGATCGGCGACGCCAAGGCGACCGACGCGGCGATCAAGGCAGCGGCGCATGTCAC
CCGCATGAAGATCGTCAACAACCGGCTGGTGCCGAATGCCATGGAGCCGCGCGCGGCTCTCGGCCACTACGACAAGGCCG
AGGACCATTATACCTGCTGGACGACCTCGCAGAACCCGCATGTCGCGCGGCTGGTGATGAGCGCCTTCTACAATGTCGCG
CCGGAAAACAAGCTGCGCGTCATCGCGCCTGACGTCGGCGGCGGCTTCGGCTCCAAGATCTACATCTATCCCGAAGAGAT
CGTCTGCCTGTGGGCTTCCAAGAAAACCGGCGTGCCGGTCAAATGGGTCGCCGACCGCACCGAGAGTTTTCTCTCCGACG
CGCATGGCCGCGACCATGTCTCGACGGTGGAAATGGCTTTCGACAAGAACAACAGGATCACCGGGCTGAAGGTCGACACG
ATCGCCAATCTCGGCGCCTACATGTCGCTGTTCTCGTCCTGCGTGCCGACCTATCTCTACGCGACATTGTTGTCGGGCCA
GTACGACATTCCGGCCATCCACGCCAATGTGCGCACGGTCTACACCAACACAGCTCCTGTCGATGCCTATCGCGGGGCAG
GGCGGCCGGAAGCCACCTATCTCCTGGAACGCACGATGGAAGCGGCGGCGCGCGAGCTTGGCGTGTCACCTGCCGAATTG
CGGCGCAAGAACTTCATCACCTCCTTCCCGCACCAGACACCGGTGATCATGAACTATGACGCCGGTGACTATGGCGCCTC
GCTCGATGCGGCCATGAAAGCTTCGGACTATGCCGGCTTTGCCAAGCGCAAGGCGGCGGCCGCCAAGAAGGGCTTGCTCC
GCGGCATCGGCATGAGCTGTTACATCGAGGCCTGCGGCATCGCGCCGTCGGCGGCGGTCGGTTCGCTCGGCGCCGGCGTT
GGCCTCTGGGAATCGGCCGAAGTGCGGGTCAATGCCGTTGGCACGATCGAGGTGCTGACCGGCTCGCACAGCCATGGCCA
GGGCCACGAGACGACCTTCGCGCAACTGGTCAACCAGCGTTTTGGCGTGCCGATCGATTCGGTTTCGATCGTCCATGGCG
ACACCGACAAGGTGCAGATGGGCATGGGCACGTACGGTTCGCGCTCGGGCGCGGTCGGCATGTCGGCGATATCAAAGGCA
CTCGACAAGGTCGAGGCCAAGGCCAAGAAGATCGCCGCCCACCTGCTCGAGGCCGACGAGGGCGACATCGTCATCGAGAA
CGGCGCGCTGAAGGTCGCCGGTACCGACAAGAACGTGCCGTGGTTCCAGGTGGCGCTGGCCGCCTATACCGCCCACAATC
TGCCGGCAGGGATGGAGCCCGGATTGAAGGAAACGGCCTTCTACGATCCGTCGAACTTCACCTTTCCGGCGGGCTGCTAC
ATCTGCGAGGTCGAGATCGAGCCGGAGACCGGAACGACCGAGATCGTCCAGTTCGTGGCCGCCGACGATTTCGGCAACAT
CATCAATCCGATGATCGTGGAAGGCCAGGTGCATGGCGGCATCGCGCAAGGGATCGGCCAGGCGCTGCTGGAAGGCGCCC
ATTACGACGCCAGCGGACAGCTGCTGACCGCGAGCTACATGGACTATACGATGCCGCGCGCGGGCGACCTGCCGTCGTTC
AAGGTCTCAACCTCGAACACGCCATGCCCGGGCAATCCGCTCGGCATCAAGGGCTGCGGCGAGGCCGGCGCCATCGGCTC
GCCGCCGGCGGTGATCAACGCCATCACCGATGCCATCGGCATCGCCGATATCGCCATGCCCGCCTCGCCGCCCACCGTGT
GGGCCGCGATCCGCGCCGCGAAGCATTGA

Upstream 100 bases:

>100_bases
GCAGTAAGGCAGTAGGGCAGTAGGGAACCGGAACCAGTTTTCCCGTACTGCCGTACTGCCCTACTCACCTACTCCCCTAC
AATCTCGGGAGGAATTTCTT

Downstream 100 bases:

>100_bases
GGAGGAACAACCATGTATTCGGTCAACTACCACCGTGCCGCCTCGGTCGCGGATGCCGCCAAGCTGGTGAAGAACGGCGA
CGCCAAGCTGCTGTCCGGCG

Product: carbon-monoxide dehydrogenase large subunit

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 782; Mature: 781

Protein sequence:

>782_residues
MGIEGVGARVARKEDKRFITGAGRYVDDMVVPGMKHAAFVRSPHAHAQIKKIDVRRAQAMPGVIGVLTGKELKADGIGNL
ICGWMIHSKDGSPMKMGAWSPLAVDKVRYVGDAVVVVVAETKGQARDAAEAVEITYKELKAVVEATKALEKGAPQIHAEA
ENNLIFDWEIGDAKATDAAIKAAAHVTRMKIVNNRLVPNAMEPRAALGHYDKAEDHYTCWTTSQNPHVARLVMSAFYNVA
PENKLRVIAPDVGGGFGSKIYIYPEEIVCLWASKKTGVPVKWVADRTESFLSDAHGRDHVSTVEMAFDKNNRITGLKVDT
IANLGAYMSLFSSCVPTYLYATLLSGQYDIPAIHANVRTVYTNTAPVDAYRGAGRPEATYLLERTMEAAARELGVSPAEL
RRKNFITSFPHQTPVIMNYDAGDYGASLDAAMKASDYAGFAKRKAAAAKKGLLRGIGMSCYIEACGIAPSAAVGSLGAGV
GLWESAEVRVNAVGTIEVLTGSHSHGQGHETTFAQLVNQRFGVPIDSVSIVHGDTDKVQMGMGTYGSRSGAVGMSAISKA
LDKVEAKAKKIAAHLLEADEGDIVIENGALKVAGTDKNVPWFQVALAAYTAHNLPAGMEPGLKETAFYDPSNFTFPAGCY
ICEVEIEPETGTTEIVQFVAADDFGNIINPMIVEGQVHGGIAQGIGQALLEGAHYDASGQLLTASYMDYTMPRAGDLPSF
KVSTSNTPCPGNPLGIKGCGEAGAIGSPPAVINAITDAIGIADIAMPASPPTVWAAIRAAKH

Sequences:

>Translated_782_residues
MGIEGVGARVARKEDKRFITGAGRYVDDMVVPGMKHAAFVRSPHAHAQIKKIDVRRAQAMPGVIGVLTGKELKADGIGNL
ICGWMIHSKDGSPMKMGAWSPLAVDKVRYVGDAVVVVVAETKGQARDAAEAVEITYKELKAVVEATKALEKGAPQIHAEA
ENNLIFDWEIGDAKATDAAIKAAAHVTRMKIVNNRLVPNAMEPRAALGHYDKAEDHYTCWTTSQNPHVARLVMSAFYNVA
PENKLRVIAPDVGGGFGSKIYIYPEEIVCLWASKKTGVPVKWVADRTESFLSDAHGRDHVSTVEMAFDKNNRITGLKVDT
IANLGAYMSLFSSCVPTYLYATLLSGQYDIPAIHANVRTVYTNTAPVDAYRGAGRPEATYLLERTMEAAARELGVSPAEL
RRKNFITSFPHQTPVIMNYDAGDYGASLDAAMKASDYAGFAKRKAAAAKKGLLRGIGMSCYIEACGIAPSAAVGSLGAGV
GLWESAEVRVNAVGTIEVLTGSHSHGQGHETTFAQLVNQRFGVPIDSVSIVHGDTDKVQMGMGTYGSRSGAVGMSAISKA
LDKVEAKAKKIAAHLLEADEGDIVIENGALKVAGTDKNVPWFQVALAAYTAHNLPAGMEPGLKETAFYDPSNFTFPAGCY
ICEVEIEPETGTTEIVQFVAADDFGNIINPMIVEGQVHGGIAQGIGQALLEGAHYDASGQLLTASYMDYTMPRAGDLPSF
KVSTSNTPCPGNPLGIKGCGEAGAIGSPPAVINAITDAIGIADIAMPASPPTVWAAIRAAKH
>Mature_781_residues
GIEGVGARVARKEDKRFITGAGRYVDDMVVPGMKHAAFVRSPHAHAQIKKIDVRRAQAMPGVIGVLTGKELKADGIGNLI
CGWMIHSKDGSPMKMGAWSPLAVDKVRYVGDAVVVVVAETKGQARDAAEAVEITYKELKAVVEATKALEKGAPQIHAEAE
NNLIFDWEIGDAKATDAAIKAAAHVTRMKIVNNRLVPNAMEPRAALGHYDKAEDHYTCWTTSQNPHVARLVMSAFYNVAP
ENKLRVIAPDVGGGFGSKIYIYPEEIVCLWASKKTGVPVKWVADRTESFLSDAHGRDHVSTVEMAFDKNNRITGLKVDTI
ANLGAYMSLFSSCVPTYLYATLLSGQYDIPAIHANVRTVYTNTAPVDAYRGAGRPEATYLLERTMEAAARELGVSPAELR
RKNFITSFPHQTPVIMNYDAGDYGASLDAAMKASDYAGFAKRKAAAAKKGLLRGIGMSCYIEACGIAPSAAVGSLGAGVG
LWESAEVRVNAVGTIEVLTGSHSHGQGHETTFAQLVNQRFGVPIDSVSIVHGDTDKVQMGMGTYGSRSGAVGMSAISKAL
DKVEAKAKKIAAHLLEADEGDIVIENGALKVAGTDKNVPWFQVALAAYTAHNLPAGMEPGLKETAFYDPSNFTFPAGCYI
CEVEIEPETGTTEIVQFVAADDFGNIINPMIVEGQVHGGIAQGIGQALLEGAHYDASGQLLTASYMDYTMPRAGDLPSFK
VSTSNTPCPGNPLGIKGCGEAGAIGSPPAVINAITDAIGIADIAMPASPPTVWAAIRAAKH

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=761, Percent_Identity=24.5729303547963, Blast_Score=147, Evalue=5e-35,
Organism=Homo sapiens, GI71773480, Length=762, Percent_Identity=25.4593175853018, Blast_Score=141, Evalue=2e-33,
Organism=Escherichia coli, GI1789230, Length=783, Percent_Identity=28.6079182630907, Blast_Score=248, Evalue=1e-66,
Organism=Escherichia coli, GI1789246, Length=818, Percent_Identity=26.039119804401, Blast_Score=208, Evalue=1e-54,
Organism=Escherichia coli, GI1786478, Length=762, Percent_Identity=24.8031496062992, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17539860, Length=797, Percent_Identity=24.9686323713927, Blast_Score=139, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17540638, Length=792, Percent_Identity=23.8636363636364, Blast_Score=128, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32566215, Length=536, Percent_Identity=23.6940298507463, Blast_Score=96, Evalue=9e-20,
Organism=Drosophila melanogaster, GI17737937, Length=801, Percent_Identity=25.7178526841448, Blast_Score=120, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 82983; Mature: 82852

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIEGVGARVARKEDKRFITGAGRYVDDMVVPGMKHAAFVRSPHAHAQIKKIDVRRAQAM
CCCCCCCHHHHHHCCCEEEEECCCHHHHHHCCCCHHHHHHCCCCCHHEEHHHHHHHHHCC
PGVIGVLTGKELKADGIGNLICGWMIHSKDGSPMKMGAWSPLAVDKVRYVGDAVVVVVAE
CCEEEEECCCCCCCCCCCCEEEEEEEECCCCCCEEECCCCCHHHHHHHHCCCEEEEEEEC
TKGQARDAAEAVEITYKELKAVVEATKALEKGAPQIHAEAENNLIFDWEIGDAKATDAAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCHHHHHH
KAAAHVTRMKIVNNRLVPNAMEPRAALGHYDKAEDHYTCWTTSQNPHVARLVMSAFYNVA
HHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCC
PENKLRVIAPDVGGGFGSKIYIYPEEIVCLWASKKTGVPVKWVADRTESFLSDAHGRDHV
CCCCEEEEECCCCCCCCCEEEEECCEEEEEEECCCCCCCEEEHHHHHHHHHHHCCCCCCC
STVEMAFDKNNRITGLKVDTIANLGAYMSLFSSCVPTYLYATLLSGQYDIPAIHANVRTV
EEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCEEEE
YTNTAPVDAYRGAGRPEATYLLERTMEAAARELGVSPAELRRKNFITSFPHQTPVIMNYD
EECCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEECC
AGDYGASLDAAMKASDYAGFAKRKAAAAKKGLLRGIGMSCYIEACGIAPSAAVGSLGAGV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCCCC
GLWESAEVRVNAVGTIEVLTGSHSHGQGHETTFAQLVNQRFGVPIDSVSIVHGDTDKVQM
CCCCCCCEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCEEEE
GMGTYGSRSGAVGMSAISKALDKVEAKAKKIAAHLLEADEGDIVIENGALKVAGTDKNVP
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCCCCC
WFQVALAAYTAHNLPAGMEPGLKETAFYDPSNFTFPAGCYICEVEIEPETGTTEIVQFVA
HHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEEECCCCCHHHHHHHHH
ADDFGNIINPMIVEGQVHGGIAQGIGQALLEGAHYDASGQLLTASYMDYTMPRAGDLPSF
HCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEHHHCCCCCCCCCCCE
KVSTSNTPCPGNPLGIKGCGEAGAIGSPPAVINAITDAIGIADIAMPASPPTVWAAIRAA
EEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHC
KH
CC
>Mature Secondary Structure 
GIEGVGARVARKEDKRFITGAGRYVDDMVVPGMKHAAFVRSPHAHAQIKKIDVRRAQAM
CCCCCCHHHHHHCCCEEEEECCCHHHHHHCCCCHHHHHHCCCCCHHEEHHHHHHHHHCC
PGVIGVLTGKELKADGIGNLICGWMIHSKDGSPMKMGAWSPLAVDKVRYVGDAVVVVVAE
CCEEEEECCCCCCCCCCCCEEEEEEEECCCCCCEEECCCCCHHHHHHHHCCCEEEEEEEC
TKGQARDAAEAVEITYKELKAVVEATKALEKGAPQIHAEAENNLIFDWEIGDAKATDAAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCHHHHHH
KAAAHVTRMKIVNNRLVPNAMEPRAALGHYDKAEDHYTCWTTSQNPHVARLVMSAFYNVA
HHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCC
PENKLRVIAPDVGGGFGSKIYIYPEEIVCLWASKKTGVPVKWVADRTESFLSDAHGRDHV
CCCCEEEEECCCCCCCCCEEEEECCEEEEEEECCCCCCCEEEHHHHHHHHHHHCCCCCCC
STVEMAFDKNNRITGLKVDTIANLGAYMSLFSSCVPTYLYATLLSGQYDIPAIHANVRTV
EEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCEEEE
YTNTAPVDAYRGAGRPEATYLLERTMEAAARELGVSPAELRRKNFITSFPHQTPVIMNYD
EECCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEEECC
AGDYGASLDAAMKASDYAGFAKRKAAAAKKGLLRGIGMSCYIEACGIAPSAAVGSLGAGV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHCCCCCC
GLWESAEVRVNAVGTIEVLTGSHSHGQGHETTFAQLVNQRFGVPIDSVSIVHGDTDKVQM
CCCCCCCEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCEEEE
GMGTYGSRSGAVGMSAISKALDKVEAKAKKIAAHLLEADEGDIVIENGALKVAGTDKNVP
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCCCCC
WFQVALAAYTAHNLPAGMEPGLKETAFYDPSNFTFPAGCYICEVEIEPETGTTEIVQFVA
HHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEEECCCCCHHHHHHHHH
ADDFGNIINPMIVEGQVHGGIAQGIGQALLEGAHYDASGQLLTASYMDYTMPRAGDLPSF
HCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEHHHCCCCCCCCCCCE
KVSTSNTPCPGNPLGIKGCGEAGAIGSPPAVINAITDAIGIADIAMPASPPTVWAAIRAA
EEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHC
KH
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]