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The map label for this gene is glpR [H]

Identifier: 13470893

GI number: 13470893

Start: 562316

End: 563083

Strand: Reverse

Name: glpR [H]

Synonym: mll0711

Alternate gene names: 13470893

Gene position: 563083-562316 (Counterclockwise)

Preceding gene: 13470894

Following gene: 13470892

Centisome position: 8.0

GC content: 60.42

Gene sequence:

>768_bases
ATGTACCTGTCGCCACGCCACGCCGAGATCATCCAGATGGCCAAGGACCATGGCCGCGTGCTGGTCGACGACCTGGCCAC
TCACTTCAATGTGACGCCGCAGACCATTCGCAAGGATCTCAACGATCTCTGCGACCAGCGGCTGCTTTCGCGCATCCATG
GCGGCGCATTGTTCCCGTCGGGTATCGAGAATATGGAGTATGAGGCCCGGCGCAAGATCGCGGCGGACGAGAAGGAAGCG
ATCGGCCGCGCGGCGGCAAGACTGATCCCTGACAACGCCTCGCTGTTCATCAATATCGGGACCACGACGGAAGCGGTCAG
CAAGGCGTTGCTCGACCATAACGGCCTGATGGTCATCACCAATAATATCAATGTTGCCAATAGGATGCGTATCTATCCTT
CGATCGAGGTGGTGATTGCCGGCGGGGTGGTGCGCGGTTCGGATGGCGGCGTCGTTGGCGAGGCAGCGGTCGACTTCATC
AGGCAGTTCAAGGTCGACTACGCCGTTATCGGCGCCTCGGCCATCGACCATGACGGCGCCTTGCTCGACTTCGACTTTCG
CGAGGTGAAGGTGGCGCAGGCGATCATTGCCAATGCCAGGCATGTGATTCTGGTCTCCGACCAGACCAAGTTCGAGCGCA
CGGCGCCGGTGCGCATCGGTCACCTGTCGCAGGTCAACACCTTCATCACCGACCGCTGCGACATTCCGTCGGTGCGCAAG
ATCTGCCAGGAGGCCGAGGTTCAGCTAATCGAGACGTCGCTTGGGTAA

Upstream 100 bases:

>100_bases
TTTGCCTTTGCAATCAGGTGATTTCCGTTAGCCGGCTTATACCTTTTCATTGCTTTCGTTTTCGGCTATAGAAAAGAAAA
ACGAAAACGGGAGGCCGTCC

Downstream 100 bases:

>100_bases
GGCCGTTTCGCGATCATGTCACGGGCCTGTGATATTTCGTTTGACATTCGTTATGAGTTCGAAATAATTCCGTCACGGTT
TCGCAAAAGACCAAAAATGG

Product: glycerol-3-phosphate regulon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MYLSPRHAEIIQMAKDHGRVLVDDLATHFNVTPQTIRKDLNDLCDQRLLSRIHGGALFPSGIENMEYEARRKIAADEKEA
IGRAAARLIPDNASLFINIGTTTEAVSKALLDHNGLMVITNNINVANRMRIYPSIEVVIAGGVVRGSDGGVVGEAAVDFI
RQFKVDYAVIGASAIDHDGALLDFDFREVKVAQAIIANARHVILVSDQTKFERTAPVRIGHLSQVNTFITDRCDIPSVRK
ICQEAEVQLIETSLG

Sequences:

>Translated_255_residues
MYLSPRHAEIIQMAKDHGRVLVDDLATHFNVTPQTIRKDLNDLCDQRLLSRIHGGALFPSGIENMEYEARRKIAADEKEA
IGRAAARLIPDNASLFINIGTTTEAVSKALLDHNGLMVITNNINVANRMRIYPSIEVVIAGGVVRGSDGGVVGEAAVDFI
RQFKVDYAVIGASAIDHDGALLDFDFREVKVAQAIIANARHVILVSDQTKFERTAPVRIGHLSQVNTFITDRCDIPSVRK
ICQEAEVQLIETSLG
>Mature_255_residues
MYLSPRHAEIIQMAKDHGRVLVDDLATHFNVTPQTIRKDLNDLCDQRLLSRIHGGALFPSGIENMEYEARRKIAADEKEA
IGRAAARLIPDNASLFINIGTTTEAVSKALLDHNGLMVITNNINVANRMRIYPSIEVVIAGGVVRGSDGGVVGEAAVDFI
RQFKVDYAVIGASAIDHDGALLDFDFREVKVAQAIIANARHVILVSDQTKFERTAPVRIGHLSQVNTFITDRCDIPSVRK
ICQEAEVQLIETSLG

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=249, Percent_Identity=45.7831325301205, Blast_Score=240, Evalue=6e-65,
Organism=Escherichia coli, GI87082344, Length=247, Percent_Identity=38.0566801619433, Blast_Score=200, Evalue=7e-53,
Organism=Escherichia coli, GI1788069, Length=252, Percent_Identity=29.3650793650794, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI226510968, Length=227, Percent_Identity=29.9559471365639, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=27.8225806451613, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789519, Length=231, Percent_Identity=28.1385281385281, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790753, Length=225, Percent_Identity=28.8888888888889, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789170, Length=232, Percent_Identity=25, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787540, Length=230, Percent_Identity=27.3913043478261, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787063, Length=250, Percent_Identity=23.2, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27966; Mature: 27966

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLSPRHAEIIQMAKDHGRVLVDDLATHFNVTPQTIRKDLNDLCDQRLLSRIHGGALFPS
CCCCCHHHHHHHHHHHCCCEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GIENMEYEARRKIAADEKEAIGRAAARLIPDNASLFINIGTTTEAVSKALLDHNGLMVIT
CCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEE
NNINVANRMRIYPSIEVVIAGGVVRGSDGGVVGEAAVDFIRQFKVDYAVIGASAIDHDGA
CCCCCCCEEEECCCEEEEEECCEEECCCCCEEHHHHHHHHHHHHHHHEEEECCCCCCCCC
LLDFDFREVKVAQAIIANARHVILVSDQTKFERTAPVRIGHLSQVNTFITDRCDIPSVRK
EEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCHHHHHHHHHCCCCCHHHHH
ICQEAEVQLIETSLG
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MYLSPRHAEIIQMAKDHGRVLVDDLATHFNVTPQTIRKDLNDLCDQRLLSRIHGGALFPS
CCCCCHHHHHHHHHHHCCCEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GIENMEYEARRKIAADEKEAIGRAAARLIPDNASLFINIGTTTEAVSKALLDHNGLMVIT
CCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCCCEEEEE
NNINVANRMRIYPSIEVVIAGGVVRGSDGGVVGEAAVDFIRQFKVDYAVIGASAIDHDGA
CCCCCCCEEEECCCEEEEEECCEEECCCCCEEHHHHHHHHHHHHHHHEEEECCCCCCCCC
LLDFDFREVKVAQAIIANARHVILVSDQTKFERTAPVRIGHLSQVNTFITDRCDIPSVRK
EEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCHHHHHHHHHCCCCCHHHHH
ICQEAEVQLIETSLG
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]