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The map label for this gene is glpD [H]

Identifier: 13470892

GI number: 13470892

Start: 560662

End: 562188

Strand: Reverse

Name: glpD [H]

Synonym: mll0710

Alternate gene names: 13470892

Gene position: 562188-560662 (Counterclockwise)

Preceding gene: 13470893

Following gene: 13470891

Centisome position: 7.99

GC content: 62.08

Gene sequence:

>1527_bases
GTGGACACGTCTTCAGTCCGGGACATTTTCGTCATAGGTGGCGGTATCAACGGTTGCGGCATAGCCCGCGATGCCGTTGG
GAGGGGGTTTTCGGTTTTTCTCGCCGAGATGAACGACCTCGCCAGCGGAACCTCCTCCGGTTCGACCAAGCTGATCCATG
GCGGCCTGCGTTATCTCGAATTCTACGAGTTCCGCCTGGTGCGCGAGGCGCTGATGGAGCGCGAGGTTTTGTGGAAGAAC
GCGCCGCACATCATCTGGCCGATGCGCTTCGTGCTGCCCTATGCCAAGGGCCTGCGTCCGGCCTGGCTGATCCGGCTCGG
CCTGTTCCTGTACGACCACATTGGCGGACGCAAATTGCTGCCGGCGACCAGGACACTCGACATGGCAAGCGATCCGGCCG
GCAAGCCTTTGAAGCCGTTGTTCAAAAAGGCGTTCGAATATTCCGATGGCTGGGTCAACGATGCGCGGCTGGTGGCGCTC
AACGCACGCGATGCCGCAGATCGTGGTGCAACGATCCGGACCCGCACGAAGGTGGTCGGCGCGCGCCGTGAAAACGGCCT
TTGGACAATCAAGATCGAGAATCTGCAGAACGGCGAGACCGAAGAGATCAAGGCGCGGCTGCTGGTCAATGCAGCCGGGC
CGTGGGTCGATCACGTGCTCTCCGGTGTCGTCGGCCTCAACGATGTGCACAATGTCCGCCTGGTGCAGGGCAGCCATATC
GTCATCGCCAAGAAGTTCGACGATCCGCGCGCCTATTTCTTCCAGAACAAGGATGGCCGCATCATCTTCGCCATCCCCTA
CGAGGACGAGTTCACGCTGATCGGCACCACCGACCGGGATTATCCCGGCGATCCGCACGATGTGAAGATCAGCGACACCG
AGATCGATTATCTCTGCGCTGCGGCCAGCGAGTATTTTGCGCAACCGGTCAAGCGCTCCGACATCGTCTGGACCTATTCG
GCCGTGCGCCCGCTCTATGATGACGGCGCCTCCAAGGCGCAGGAAGCGACGCGCGACTATGTGCTGAAGGCCGATGGCGG
CGAGGGTACCGCTCCGATCGTCAATGCCTTCGGCGGCAAAATCACCACCTACCGCCGGCTGTCGGAATCGATGCTGGAGA
AGATCGAAGGTTTTCTCGGCAAGCGCGGCAAGCCGTGGACATCGGACGCGCCGCTGCCGGGCGGCGATTTCCCGGCGACC
GGTTTCGACGCGCAGGTGGCGAAGTTGAAGACAGCCTATCCTTTCCTCGACGCGCGCCTGGCCCGTCGGCTGACGCGGCT
TTACGGGACGCGGGCTCAGCGTCTGCTTGGCCTTGCCAAATCGAATGCCGAACTCGGCCGCAATTTCGGCGGCGATCTCT
ATGAGGCCGAAGTTCGCTATCTCGTTGAAAACGAATGGGCTCTTACGGCGGAAGACGTGCTGTGGCGCCGCACCAAGCGC
GGCCTGCATCTCAGCCGCGAACACGTCGCGGCACTCGATGAATTCATGCGCGGCATAAGCCGGCGGCACGTCGCGGCCGC
CGAATGA

Upstream 100 bases:

>100_bases
TGTGATATTTCGTTTGACATTCGTTATGAGTTCGAAATAATTCCGTCACGGTTTCGCAAAAGACCAAAAATGGTGCAATG
CGAAATCGTGGAGGAGTTAA

Downstream 100 bases:

>100_bases
AGAGGGTCTTGAGCTGATGCGGAAAGCCTGGGAGGAGGCGTCATGCTTGAACTGAGGAACGTCACCAAGACGGTCGGTGC
GGTCGAGCACATACGTGATG

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MDTSSVRDIFVIGGGINGCGIARDAVGRGFSVFLAEMNDLASGTSSGSTKLIHGGLRYLEFYEFRLVREALMEREVLWKN
APHIIWPMRFVLPYAKGLRPAWLIRLGLFLYDHIGGRKLLPATRTLDMASDPAGKPLKPLFKKAFEYSDGWVNDARLVAL
NARDAADRGATIRTRTKVVGARRENGLWTIKIENLQNGETEEIKARLLVNAAGPWVDHVLSGVVGLNDVHNVRLVQGSHI
VIAKKFDDPRAYFFQNKDGRIIFAIPYEDEFTLIGTTDRDYPGDPHDVKISDTEIDYLCAAASEYFAQPVKRSDIVWTYS
AVRPLYDDGASKAQEATRDYVLKADGGEGTAPIVNAFGGKITTYRRLSESMLEKIEGFLGKRGKPWTSDAPLPGGDFPAT
GFDAQVAKLKTAYPFLDARLARRLTRLYGTRAQRLLGLAKSNAELGRNFGGDLYEAEVRYLVENEWALTAEDVLWRRTKR
GLHLSREHVAALDEFMRGISRRHVAAAE

Sequences:

>Translated_508_residues
MDTSSVRDIFVIGGGINGCGIARDAVGRGFSVFLAEMNDLASGTSSGSTKLIHGGLRYLEFYEFRLVREALMEREVLWKN
APHIIWPMRFVLPYAKGLRPAWLIRLGLFLYDHIGGRKLLPATRTLDMASDPAGKPLKPLFKKAFEYSDGWVNDARLVAL
NARDAADRGATIRTRTKVVGARRENGLWTIKIENLQNGETEEIKARLLVNAAGPWVDHVLSGVVGLNDVHNVRLVQGSHI
VIAKKFDDPRAYFFQNKDGRIIFAIPYEDEFTLIGTTDRDYPGDPHDVKISDTEIDYLCAAASEYFAQPVKRSDIVWTYS
AVRPLYDDGASKAQEATRDYVLKADGGEGTAPIVNAFGGKITTYRRLSESMLEKIEGFLGKRGKPWTSDAPLPGGDFPAT
GFDAQVAKLKTAYPFLDARLARRLTRLYGTRAQRLLGLAKSNAELGRNFGGDLYEAEVRYLVENEWALTAEDVLWRRTKR
GLHLSREHVAALDEFMRGISRRHVAAAE
>Mature_508_residues
MDTSSVRDIFVIGGGINGCGIARDAVGRGFSVFLAEMNDLASGTSSGSTKLIHGGLRYLEFYEFRLVREALMEREVLWKN
APHIIWPMRFVLPYAKGLRPAWLIRLGLFLYDHIGGRKLLPATRTLDMASDPAGKPLKPLFKKAFEYSDGWVNDARLVAL
NARDAADRGATIRTRTKVVGARRENGLWTIKIENLQNGETEEIKARLLVNAAGPWVDHVLSGVVGLNDVHNVRLVQGSHI
VIAKKFDDPRAYFFQNKDGRIIFAIPYEDEFTLIGTTDRDYPGDPHDVKISDTEIDYLCAAASEYFAQPVKRSDIVWTYS
AVRPLYDDGASKAQEATRDYVLKADGGEGTAPIVNAFGGKITTYRRLSESMLEKIEGFLGKRGKPWTSDAPLPGGDFPAT
GFDAQVAKLKTAYPFLDARLARRLTRLYGTRAQRLLGLAKSNAELGRNFGGDLYEAEVRYLVENEWALTAEDVLWRRTKR
GLHLSREHVAALDEFMRGISRRHVAAAE

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=513, Percent_Identity=30.9941520467836, Blast_Score=179, Evalue=7e-45,
Organism=Homo sapiens, GI285002231, Length=513, Percent_Identity=30.9941520467836, Blast_Score=179, Evalue=7e-45,
Organism=Escherichia coli, GI2367226, Length=478, Percent_Identity=47.6987447698745, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1788574, Length=489, Percent_Identity=27.6073619631902, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI115534726, Length=512, Percent_Identity=29.6875, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17509253, Length=508, Percent_Identity=29.3307086614173, Blast_Score=156, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6322036, Length=551, Percent_Identity=28.8566243194192, Blast_Score=155, Evalue=1e-38,
Organism=Drosophila melanogaster, GI161077125, Length=512, Percent_Identity=29.8828125, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24653942, Length=512, Percent_Identity=29.8828125, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24653944, Length=512, Percent_Identity=29.8828125, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI20130025, Length=512, Percent_Identity=29.8828125, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24586295, Length=506, Percent_Identity=27.0750988142292, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI19921278, Length=501, Percent_Identity=22.3552894211577, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56639; Mature: 56639

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00977 FAD_G3PDH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTSSVRDIFVIGGGINGCGIARDAVGRGFSVFLAEMNDLASGTSSGSTKLIHGGLRYLE
CCCCCCCEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHH
FYEFRLVREALMEREVLWKNAPHIIWPMRFVLPYAKGLRPAWLIRLGLFLYDHIGGRKLL
HHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEC
PATRTLDMASDPAGKPLKPLFKKAFEYSDGWVNDARLVALNARDAADRGATIRTRTKVVG
CCHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEEEHHHHHC
ARRENGLWTIKIENLQNGETEEIKARLLVNAAGPWVDHVLSGVVGLNDVHNVRLVQGSHI
CCCCCCEEEEEECCCCCCCHHHHEEEEEEECCCHHHHHHHHHHCCCCCCCCEEEEECCEE
VIAKKFDDPRAYFFQNKDGRIIFAIPYEDEFTLIGTTDRDYPGDPHDVKISDTEIDYLCA
EEEEECCCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHH
AASEYFAQPVKRSDIVWTYSAVRPLYDDGASKAQEATRDYVLKADGGEGTAPIVNAFGGK
HHHHHHHCCCCCCCEEEEHHHHCCHHCCCHHHHHHHHHCEEEEECCCCCCCHHHHHCCCC
ITTYRRLSESMLEKIEGFLGKRGKPWTSDAPLPGGDFPATGFDAQVAKLKTAYPFLDARL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHH
ARRLTRLYGTRAQRLLGLAKSNAELGRNFGGDLYEAEVRYLVENEWALTAEDVLWRRTKR
HHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHEEECCCCCCCHHHHHHHHHHC
GLHLSREHVAALDEFMRGISRRHVAAAE
CCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDTSSVRDIFVIGGGINGCGIARDAVGRGFSVFLAEMNDLASGTSSGSTKLIHGGLRYLE
CCCCCCCEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHH
FYEFRLVREALMEREVLWKNAPHIIWPMRFVLPYAKGLRPAWLIRLGLFLYDHIGGRKLL
HHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEC
PATRTLDMASDPAGKPLKPLFKKAFEYSDGWVNDARLVALNARDAADRGATIRTRTKVVG
CCHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCEEEEHHHHHC
ARRENGLWTIKIENLQNGETEEIKARLLVNAAGPWVDHVLSGVVGLNDVHNVRLVQGSHI
CCCCCCEEEEEECCCCCCCHHHHEEEEEEECCCHHHHHHHHHHCCCCCCCCEEEEECCEE
VIAKKFDDPRAYFFQNKDGRIIFAIPYEDEFTLIGTTDRDYPGDPHDVKISDTEIDYLCA
EEEEECCCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHH
AASEYFAQPVKRSDIVWTYSAVRPLYDDGASKAQEATRDYVLKADGGEGTAPIVNAFGGK
HHHHHHHCCCCCCCEEEEHHHHCCHHCCCHHHHHHHHHCEEEEECCCCCCCHHHHHCCCC
ITTYRRLSESMLEKIEGFLGKRGKPWTSDAPLPGGDFPATGFDAQVAKLKTAYPFLDARL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHH
ARRLTRLYGTRAQRLLGLAKSNAELGRNFGGDLYEAEVRYLVENEWALTAEDVLWRRTKR
HHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHEEECCCCCCCHHHHHHHHHHC
GLHLSREHVAALDEFMRGISRRHVAAAE
CCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]