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The map label for this gene is otsB [H]

Identifier: 13470876

GI number: 13470876

Start: 540603

End: 541394

Strand: Reverse

Name: otsB [H]

Synonym: mll0690

Alternate gene names: 13470876

Gene position: 541394-540603 (Counterclockwise)

Preceding gene: 13470877

Following gene: 13470871

Centisome position: 7.69

GC content: 62.88

Gene sequence:

>792_bases
ATGATCTCTCTCTCGCCAAACCTCGCCGTGCCTGTCGTTCCGCAAGGGCCATGCAGCCTGTTCCTCGATATCGACGGCAC
GCTTCTCGAACATGCCGCGCATCCCGATGCGGTGGTTGTCGGTGATGAATTGCGCACCCTGCTGGTGCGGCTCGAAGCGC
AACTGGACGGAGCACTGGCGTTCATCACGGGACGCTCGATCGCCGCCGTCGACCATCTCTTCCGGCCTCTCAGGCTGCGC
GCCGCGGGGCTTTACGGCCTCGAGCACAGGCTGGCGCGCGATGGTCCGGTCGAGGCGGCCAGCGAGCCGGCTGATATTGC
AGCTCTTGCCAACGAAATCGCGACGGAACTGGACAATGCAGATGTCTATATCGAGCGCAAGGGACCCATCCTGGCCATTC
ATACACGCGCGGCACCGCATTTGCTTCAACGCGCGACGGAGTTGGTCGAACAGGCACTAGACAGATTGCCTGCGGGATAC
CGGGTTTTGGCCGGAAATGCCGGTGTGGAACTGATGCCGCTGGAGGCGGCGAAGGGAGCAGCCATCCGGCGCTTCATGCA
AATTCCGGCTTTCAGGGGACGGCGCCCGGTGTTCCTCGGGGACGATACATCCGACGAGAACGGGTTCGAGACCGTCAACG
AATTGGACGGCATCTCGGTTCGCATAAAGCCGCAGGGATCGACAGCTGCACCTTTTGCACTGGCCGGCGTGGACGCGGCC
TTGGCCTGGCTGGACGAGATGAGCAGGAGCGAGACCGCGAAAGCGGCGACGCTGGCCGCAATGCCCAAATGA

Upstream 100 bases:

>100_bases
GCTTGCGCAAGCGCGACGCGGTCGATCGCGCCGTCAGCGCCGCTCCAGCGGCCCCAGCCAATGTCATATCGCTGCTCGAT
CGCAGACGCGTGGCGGCGCT

Downstream 100 bases:

>100_bases
ACCGGATTGCCCTGAGGCAATCCCGGTTCGCGCGCATGGAAGGAGTTTGCAATGACCCAATTGACCAGCCTCATTCGGGA
AGTCATGCCCGCCTGGCTCC

Product: trehalose-6-phosphate phosphatase

Products: NA

Alternate protein names: TPP; Trehalose 6-phosphate phosphatase; Trehalose-phosphatase [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MISLSPNLAVPVVPQGPCSLFLDIDGTLLEHAAHPDAVVVGDELRTLLVRLEAQLDGALAFITGRSIAAVDHLFRPLRLR
AAGLYGLEHRLARDGPVEAASEPADIAALANEIATELDNADVYIERKGPILAIHTRAAPHLLQRATELVEQALDRLPAGY
RVLAGNAGVELMPLEAAKGAAIRRFMQIPAFRGRRPVFLGDDTSDENGFETVNELDGISVRIKPQGSTAAPFALAGVDAA
LAWLDEMSRSETAKAATLAAMPK

Sequences:

>Translated_263_residues
MISLSPNLAVPVVPQGPCSLFLDIDGTLLEHAAHPDAVVVGDELRTLLVRLEAQLDGALAFITGRSIAAVDHLFRPLRLR
AAGLYGLEHRLARDGPVEAASEPADIAALANEIATELDNADVYIERKGPILAIHTRAAPHLLQRATELVEQALDRLPAGY
RVLAGNAGVELMPLEAAKGAAIRRFMQIPAFRGRRPVFLGDDTSDENGFETVNELDGISVRIKPQGSTAAPFALAGVDAA
LAWLDEMSRSETAKAATLAAMPK
>Mature_263_residues
MISLSPNLAVPVVPQGPCSLFLDIDGTLLEHAAHPDAVVVGDELRTLLVRLEAQLDGALAFITGRSIAAVDHLFRPLRLR
AAGLYGLEHRLARDGPVEAASEPADIAALANEIATELDNADVYIERKGPILAIHTRAAPHLLQRATELVEQALDRLPAGY
RVLAGNAGVELMPLEAAKGAAIRRFMQIPAFRGRRPVFLGDDTSDENGFETVNELDGISVRIKPQGSTAAPFALAGVDAA
LAWLDEMSRSETAKAATLAAMPK

Specific function: Removes the phosphate from trehalose 6-phosphate to produce free trehalose [H]

COG id: COG1877

COG function: function code G; Trehalose-6-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trehalose phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788207, Length=243, Percent_Identity=39.5061728395062, Blast_Score=134, Evalue=4e-33,
Organism=Drosophila melanogaster, GI19920676, Length=268, Percent_Identity=24.6268656716418, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR003337 [H]

Pfam domain/function: PF02358 Trehalose_PPase [H]

EC number: =3.1.3.12 [H]

Molecular weight: Translated: 27985; Mature: 27985

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISLSPNLAVPVVPQGPCSLFLDIDGTLLEHAAHPDAVVVGDELRTLLVRLEAQLDGALA
CEECCCCCEEEECCCCCCEEEEECCCHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCEEE
FITGRSIAAVDHLFRPLRLRAAGLYGLEHRLARDGPVEAASEPADIAALANEIATELDNA
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
DVYIERKGPILAIHTRAAPHLLQRATELVEQALDRLPAGYRVLAGNAGVELMPLEAAKGA
CEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCH
AIRRFMQIPAFRGRRPVFLGDDTSDENGFETVNELDGISVRIKPQGSTAAPFALAGVDAA
HHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHH
LAWLDEMSRSETAKAATLAAMPK
HHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MISLSPNLAVPVVPQGPCSLFLDIDGTLLEHAAHPDAVVVGDELRTLLVRLEAQLDGALA
CEECCCCCEEEECCCCCCEEEEECCCHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCEEE
FITGRSIAAVDHLFRPLRLRAAGLYGLEHRLARDGPVEAASEPADIAALANEIATELDNA
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
DVYIERKGPILAIHTRAAPHLLQRATELVEQALDRLPAGYRVLAGNAGVELMPLEAAKGA
CEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCH
AIRRFMQIPAFRGRRPVFLGDDTSDENGFETVNELDGISVRIKPQGSTAAPFALAGVDAA
HHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHH
LAWLDEMSRSETAKAATLAAMPK
HHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]