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The map label for this gene is aidB [H]

Identifier: 13470871

GI number: 13470871

Start: 534491

End: 536137

Strand: Reverse

Name: aidB [H]

Synonym: mll0685

Alternate gene names: 13470871

Gene position: 536137-534491 (Counterclockwise)

Preceding gene: 13470876

Following gene: 13470870

Centisome position: 7.62

GC content: 67.15

Gene sequence:

>1647_bases
TTGCGACAAGGACAAAGCGTGACCGACGACGTGACGAACCAGCCGCCGCCGCTGACGGGCGGCAACGCCTGGCGGGGCGA
TCCGTTGCTGATCCAGCTTGCCGAGCGGTTTTCCGACCCGGTGCGCAAAGACCTCGACGGGCTCGGCCGTTTCGTGCTGA
CGCAGGAGGCGCAGGAGCTGGCGCGCCTGGCCAATGTCGAGACGCCGAAGCTCAGGACCCATGACCGCCAGGGACGGCGC
ATCGACCTGGTCGAGTTCCACCCCGCCTACCATGCCTTGATGCGCCGCTCGGTGGCCAACGGGTTGCATTCCTCGGTTTG
GGAAAATGGCGATGCCGAGATCGGCCGCCGCCATCAGGTGCGCGCCGCACGCTTCTACCTGACCGCCGAACTCGAAACCG
GGCATCTCTGCCCCATCACCATGACCAGCGCCTCGCTGGCGGCGTTGATGGCCAGCCCAAAGTTGTTTCGCGAATGGGCC
CCGCGCGTGACGACGCGCAAATACGACCAGAGCCAGAAGCCGCCGGTCGAGAAGACCGGGCTGACGCTCGGCATGGGCAT
GACCGAAAAACAGGGCGGCACGGATGTGCGCGCCAATGTGACGAGGGCCGAGCGCGCCGGCAGCGGCTTCTATCGCCTGA
CCGGCCACAAATGGTTCATGTCGGCACCGATGTCGGACGCCTTCCTGGTGCTGGCTCAGGCGCCGGAAGGACTGTCGTGC
TTCCTCGTGCCGCGCGTCCTCGGCGATGGATCGGGCAACGGCTTCCGCTTCCAGCGGCTGAAGGACAAGCTCGGCAACCG
CTCCAACGCCTCTTCCGAAGTCGAGTTCGTCAACGCCATCGGCGAGATGATCGGCGAGCCCGGCGCCGGCGTGAAGACGA
TCATGGACATGGTGACCTTGACCCGGCTCGATTGCGCCGTGGCGTCCTCGGCGATCATGCGGGCAGGGCTGGCGGAAGCG
GTTCATCATGCCCGCCATCGCCAGGTGTTCGGCTCTACCTTGATCGAACAGCCGCTCATGCAACGCGTGCTGGCCGACAT
GGCGCTGGATGTTGCCGCCGCAACCGCTCTGTCGTTCCGGTTGGCGCGCTCCTTCGACGAGGCGGCGAGCGATCGCGGCG
AAGCGGCGTTTGCCCGCGCCATGACGCCGGTCGTTAAATACTGGGTGTGCAAGATCGCGCCGCCGCTGCTCTACGAGGCG
ATGGAGTGTCTCGGCGGCAATGGCTACGTCGAGGAGGCGCCGCTCGCCCGCTATTATCGCGAAGCGCCTGTCAACGCGAT
CTGGGAAGGGTCGGGCAATGTCATGGCGCTCGACGTGCTGCGCGTGCTCGGGCGCGCGCCCGGCCTGTTCGAAGAGGTGC
TGGCCGGCATCGACCGCGACCTCGGCGCCGGTGGGCGCGGCACGATCGGCGTGTTGAAGGCGGCGATGCAGGTGGCTTTG
ACCGATGAGGGCTCGGCCCGGCTGCTGACCGAACAGCTGGCGTTGTCGGCCGCCGCGGCGGAGCTGCGCCGGCTGGGGGC
AGGGCGGATTGCCGATGCCTTCGTCGAGACCCGCCTGGCCGGCCAGTGGCGCAACACCTACGGCATGATCGATTCGCGCC
ATGACGCGCGCATGATCATCGACACGCTCTATCCGCCGGTGAACTGA

Upstream 100 bases:

>100_bases
AGCGCCAGCTTTGGATTGGCGCTGTTCTCCCCGGTATTTTCGTCGCGCGCGCGGCAACGCTTGGCTATATCTAGCCGATG
GCTTCGGATTCGAAGTCTTC

Downstream 100 bases:

>100_bases
GCCGAGAGCGGCCGCATCGCCCGATTCTTCGATCAGTTGAGCGCATCTGGGAACAGTGGGTGCGTCCTGTGGATCGCCGT
TAACCTTAACAAATGGTTTC

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MRQGQSVTDDVTNQPPPLTGGNAWRGDPLLIQLAERFSDPVRKDLDGLGRFVLTQEAQELARLANVETPKLRTHDRQGRR
IDLVEFHPAYHALMRRSVANGLHSSVWENGDAEIGRRHQVRAARFYLTAELETGHLCPITMTSASLAALMASPKLFREWA
PRVTTRKYDQSQKPPVEKTGLTLGMGMTEKQGGTDVRANVTRAERAGSGFYRLTGHKWFMSAPMSDAFLVLAQAPEGLSC
FLVPRVLGDGSGNGFRFQRLKDKLGNRSNASSEVEFVNAIGEMIGEPGAGVKTIMDMVTLTRLDCAVASSAIMRAGLAEA
VHHARHRQVFGSTLIEQPLMQRVLADMALDVAAATALSFRLARSFDEAASDRGEAAFARAMTPVVKYWVCKIAPPLLYEA
MECLGGNGYVEEAPLARYYREAPVNAIWEGSGNVMALDVLRVLGRAPGLFEEVLAGIDRDLGAGGRGTIGVLKAAMQVAL
TDEGSARLLTEQLALSAAAAELRRLGAGRIADAFVETRLAGQWRNTYGMIDSRHDARMIIDTLYPPVN

Sequences:

>Translated_548_residues
MRQGQSVTDDVTNQPPPLTGGNAWRGDPLLIQLAERFSDPVRKDLDGLGRFVLTQEAQELARLANVETPKLRTHDRQGRR
IDLVEFHPAYHALMRRSVANGLHSSVWENGDAEIGRRHQVRAARFYLTAELETGHLCPITMTSASLAALMASPKLFREWA
PRVTTRKYDQSQKPPVEKTGLTLGMGMTEKQGGTDVRANVTRAERAGSGFYRLTGHKWFMSAPMSDAFLVLAQAPEGLSC
FLVPRVLGDGSGNGFRFQRLKDKLGNRSNASSEVEFVNAIGEMIGEPGAGVKTIMDMVTLTRLDCAVASSAIMRAGLAEA
VHHARHRQVFGSTLIEQPLMQRVLADMALDVAAATALSFRLARSFDEAASDRGEAAFARAMTPVVKYWVCKIAPPLLYEA
MECLGGNGYVEEAPLARYYREAPVNAIWEGSGNVMALDVLRVLGRAPGLFEEVLAGIDRDLGAGGRGTIGVLKAAMQVAL
TDEGSARLLTEQLALSAAAAELRRLGAGRIADAFVETRLAGQWRNTYGMIDSRHDARMIIDTLYPPVN
>Mature_548_residues
MRQGQSVTDDVTNQPPPLTGGNAWRGDPLLIQLAERFSDPVRKDLDGLGRFVLTQEAQELARLANVETPKLRTHDRQGRR
IDLVEFHPAYHALMRRSVANGLHSSVWENGDAEIGRRHQVRAARFYLTAELETGHLCPITMTSASLAALMASPKLFREWA
PRVTTRKYDQSQKPPVEKTGLTLGMGMTEKQGGTDVRANVTRAERAGSGFYRLTGHKWFMSAPMSDAFLVLAQAPEGLSC
FLVPRVLGDGSGNGFRFQRLKDKLGNRSNASSEVEFVNAIGEMIGEPGAGVKTIMDMVTLTRLDCAVASSAIMRAGLAEA
VHHARHRQVFGSTLIEQPLMQRVLADMALDVAAATALSFRLARSFDEAASDRGEAAFARAMTPVVKYWVCKIAPPLLYEA
MECLGGNGYVEEAPLARYYREAPVNAIWEGSGNVMALDVLRVLGRAPGLFEEVLAGIDRDLGAGGRGTIGVLKAAMQVAL
TDEGSARLLTEQLALSAAAAELRRLGAGRIADAFVETRLAGQWRNTYGMIDSRHDARMIIDTLYPPVN

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=262, Percent_Identity=31.2977099236641, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI226958414, Length=297, Percent_Identity=27.6094276094276, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI226958412, Length=297, Percent_Identity=27.6094276094276, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI4501859, Length=257, Percent_Identity=26.8482490272374, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI4557235, Length=269, Percent_Identity=27.1375464684015, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI76496475, Length=269, Percent_Identity=27.1375464684015, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI4501857, Length=276, Percent_Identity=27.1739130434783, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI4557231, Length=274, Percent_Identity=27.3722627737226, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI187960098, Length=274, Percent_Identity=27.3722627737226, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI7656849, Length=278, Percent_Identity=26.6187050359712, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI21361497, Length=378, Percent_Identity=25.3968253968254, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI4503943, Length=285, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI87082384, Length=514, Percent_Identity=47.4708171206226, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI87081958, Length=258, Percent_Identity=26.3565891472868, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI86563383, Length=447, Percent_Identity=34.675615212528, Blast_Score=205, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI86563381, Length=447, Percent_Identity=34.675615212528, Blast_Score=204, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI17538396, Length=270, Percent_Identity=28.5185185185185, Blast_Score=99, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17508101, Length=258, Percent_Identity=25.968992248062, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17506239, Length=266, Percent_Identity=25.5639097744361, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71985184, Length=368, Percent_Identity=25, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17569725, Length=269, Percent_Identity=25.6505576208178, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17534899, Length=269, Percent_Identity=25.2788104089219, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17533517, Length=267, Percent_Identity=24.7191011235955, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=221, Percent_Identity=27.6018099547511, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17570075, Length=269, Percent_Identity=24.1635687732342, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71990804, Length=298, Percent_Identity=24.496644295302, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21356377, Length=271, Percent_Identity=30.2583025830258, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21355753, Length=262, Percent_Identity=27.8625954198473, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281363737, Length=287, Percent_Identity=25.7839721254355, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24646207, Length=397, Percent_Identity=25.6926952141058, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24666513, Length=270, Percent_Identity=24.8148148148148, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24660351, Length=274, Percent_Identity=27.007299270073, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 59742; Mature: 59742

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQGQSVTDDVTNQPPPLTGGNAWRGDPLLIQLAERFSDPVRKDLDGLGRFVLTQEAQEL
CCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ARLANVETPKLRTHDRQGRRIDLVEFHPAYHALMRRSVANGLHSSVWENGDAEIGRRHQV
HHHHCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHH
RAARFYLTAELETGHLCPITMTSASLAALMASPKLFREWAPRVTTRKYDQSQKPPVEKTG
EEEEEEEEEECCCCCCCEEEECHHHHHHHHHCHHHHHHHCCCCHHHHCCCCCCCCCHHCC
LTLGMGMTEKQGGTDVRANVTRAERAGSGFYRLTGHKWFMSAPMSDAFLVLAQAPEGLSC
EEEECCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEEEEECCCCCEE
FLVPRVLGDGSGNGFRFQRLKDKLGNRSNASSEVEFVNAIGEMIGEPGAGVKTIMDMVTL
EEEHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
TRLDCAVASSAIMRAGLAEAVHHARHRQVFGSTLIEQPLMQRVLADMALDVAAATALSFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARSFDEAASDRGEAAFARAMTPVVKYWVCKIAPPLLYEAMECLGGNGYVEEAPLARYYR
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHH
EAPVNAIWEGSGNVMALDVLRVLGRAPGLFEEVLAGIDRDLGAGGRGTIGVLKAAMQVAL
HCCCCEEECCCCCEEHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHC
TDEGSARLLTEQLALSAAAAELRRLGAGRIADAFVETRLAGQWRNTYGMIDSRHDARMII
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
DTLYPPVN
HHHCCCCC
>Mature Secondary Structure
MRQGQSVTDDVTNQPPPLTGGNAWRGDPLLIQLAERFSDPVRKDLDGLGRFVLTQEAQEL
CCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ARLANVETPKLRTHDRQGRRIDLVEFHPAYHALMRRSVANGLHSSVWENGDAEIGRRHQV
HHHHCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHH
RAARFYLTAELETGHLCPITMTSASLAALMASPKLFREWAPRVTTRKYDQSQKPPVEKTG
EEEEEEEEEECCCCCCCEEEECHHHHHHHHHCHHHHHHHCCCCHHHHCCCCCCCCCHHCC
LTLGMGMTEKQGGTDVRANVTRAERAGSGFYRLTGHKWFMSAPMSDAFLVLAQAPEGLSC
EEEECCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEEEEECCCCCEE
FLVPRVLGDGSGNGFRFQRLKDKLGNRSNASSEVEFVNAIGEMIGEPGAGVKTIMDMVTL
EEEHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
TRLDCAVASSAIMRAGLAEAVHHARHRQVFGSTLIEQPLMQRVLADMALDVAAATALSFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARSFDEAASDRGEAAFARAMTPVVKYWVCKIAPPLLYEAMECLGGNGYVEEAPLARYYR
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHH
EAPVNAIWEGSGNVMALDVLRVLGRAPGLFEEVLAGIDRDLGAGGRGTIGVLKAAMQVAL
HCCCCEEECCCCCEEHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHC
TDEGSARLLTEQLALSAAAAELRRLGAGRIADAFVETRLAGQWRNTYGMIDSRHDARMII
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
DTLYPPVN
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]