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The map label for this gene is sdaA [H]

Identifier: 13470860

GI number: 13470860

Start: 526193

End: 527596

Strand: Reverse

Name: sdaA [H]

Synonym: mll0670

Alternate gene names: 13470860

Gene position: 527596-526193 (Counterclockwise)

Preceding gene: 13470862

Following gene: 13470859

Centisome position: 7.5

GC content: 66.38

Gene sequence:

>1404_bases
GTGTTCCTTTCGGTTTTCGACCTGTTCAAGATCGGCATCGGCCCCTCGAGCTCGCACACGATGGGCCCGATGACGGCCGC
GCGGCGGTTTCTCGACGAGGTCGCGGGTGACGACTGGCCGCGGCCCACCGGCGCCAAGGTCGCCCGCATCGGCGCCAGCC
TGCACGGCTCGCTCGCCTATACTGGCATCGGCCATGGCAGCGACCGCGCCGTCATCCTCGGCCTTGCCGGCCAGACCCCG
CAAACGGTTGATCCGGACCAGGCCGATGGCATCATCGGCCGCATCACCGCCGACAGGATGATTTCGCCGCCCGGTCACCC
GTCCTACCATTTCGACCCGGCCACGGATCTGGTGCTCGACCGCAAGACACCGCTTACCGGCCACGCCAACGGCATGGCGT
TCTATGCCTATGACGCCAGCGGGCGCCTGCTGCTCAAACGCATCTACTATTCGATCGGCGGCGGCTTCGTGGTGTCGGAA
GAAGAGCTGCAGCGGATGAAGGCCAAGGGGTCGGTGACTTCAGAAGGCAAGAAAGTGCCTTATCCTTTCAAGAACGCCGT
CGAGATGCTGAAGATGGCGGCCAAGAGCGGGCTTTCCATCGCCGAGATGAAGCGCGTCAACGAGGAAACGCAGATGTCGC
GCGAGGACCTCGACGCCGGCCTCGACGCCATCTGGGGGGCTATGAAGAGCTGCATCGACCGTGGCCTGTCGCAGGACGGC
ATCATGCCGGGCGGGTTGAAGGTTCGGCGCCGGGCCCGGCAGCTGCACGACAAGCTGCAGGAACAGTGGCAGCAGAACCG
GCCAAATCCCTTGCTCGCCAATGACTGGCTGTCGATCTACGCCATGGCGGTCAACGAGGAGAATGCGGCCGGCGGCCGCG
TTGTTACCGCGCCGACCAACGGGGCGGCCGGTACGCTGCCGGCGGTGCTGCGCTACTGGCTGCATTTCCATCCCGAAGCC
GACCAGCCGAGCATACGCGACTTCCTGCTGACGGCTGCCGCCGTCGGCGGCATCATCAAGACCAATGCGTCGATCTCTGG
CGCCGAGGTCGGCTGCCAGGGCGAGGTCGGGTCCGCCTCGGCGATGGCCGCGGCCGGCCTGTGCGCCGTCATGGGCGGCA
CGCCCGAGCAGGTCGAGAATGCCGCCGAGATCGCGCTCGAACACCATCTCGGCATGACTTGCGATCCAGTCGGCGGGCTG
GTCCAGGTGCCGTGCATCGAGCGCAATGCGCTGGGCGCGGTCAAGGCGGTGACGGCTGCGTCCCTGGCGATCAAGGGCGA
CGGCATCCACTTCGTGCCGCTCGACGCGGCGATCGAGACCATGCGCCAGACCGGCCTCGACATGAACGAGAAGTACAAGG
AAACCAGCCTCGGCGGGCTCGCGGTCAATGTCGTGGAGTGCTGA

Upstream 100 bases:

>100_bases
AGCAAACAAGGTCGGCAGGTGCTGCGCCGCGATCGCCAAAAGAGCGGAAACATCCGGGGAATTCCTATATGTAGTCCTCG
ATGTGACTCCAGGAGACAGC

Downstream 100 bases:

>100_bases
GCAACGCTGGCACTGTGGAGAAGTCCGTCAGGCCGTTGACGTCCCGGCGCTCCGGACTAACCTTAGCGAATGGCTCTCAA
TCTCCTAAAACTGTGCGTCG

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MFLSVFDLFKIGIGPSSSHTMGPMTAARRFLDEVAGDDWPRPTGAKVARIGASLHGSLAYTGIGHGSDRAVILGLAGQTP
QTVDPDQADGIIGRITADRMISPPGHPSYHFDPATDLVLDRKTPLTGHANGMAFYAYDASGRLLLKRIYYSIGGGFVVSE
EELQRMKAKGSVTSEGKKVPYPFKNAVEMLKMAAKSGLSIAEMKRVNEETQMSREDLDAGLDAIWGAMKSCIDRGLSQDG
IMPGGLKVRRRARQLHDKLQEQWQQNRPNPLLANDWLSIYAMAVNEENAAGGRVVTAPTNGAAGTLPAVLRYWLHFHPEA
DQPSIRDFLLTAAAVGGIIKTNASISGAEVGCQGEVGSASAMAAAGLCAVMGGTPEQVENAAEIALEHHLGMTCDPVGGL
VQVPCIERNALGAVKAVTAASLAIKGDGIHFVPLDAAIETMRQTGLDMNEKYKETSLGGLAVNVVEC

Sequences:

>Translated_467_residues
MFLSVFDLFKIGIGPSSSHTMGPMTAARRFLDEVAGDDWPRPTGAKVARIGASLHGSLAYTGIGHGSDRAVILGLAGQTP
QTVDPDQADGIIGRITADRMISPPGHPSYHFDPATDLVLDRKTPLTGHANGMAFYAYDASGRLLLKRIYYSIGGGFVVSE
EELQRMKAKGSVTSEGKKVPYPFKNAVEMLKMAAKSGLSIAEMKRVNEETQMSREDLDAGLDAIWGAMKSCIDRGLSQDG
IMPGGLKVRRRARQLHDKLQEQWQQNRPNPLLANDWLSIYAMAVNEENAAGGRVVTAPTNGAAGTLPAVLRYWLHFHPEA
DQPSIRDFLLTAAAVGGIIKTNASISGAEVGCQGEVGSASAMAAAGLCAVMGGTPEQVENAAEIALEHHLGMTCDPVGGL
VQVPCIERNALGAVKAVTAASLAIKGDGIHFVPLDAAIETMRQTGLDMNEKYKETSLGGLAVNVVEC
>Mature_467_residues
MFLSVFDLFKIGIGPSSSHTMGPMTAARRFLDEVAGDDWPRPTGAKVARIGASLHGSLAYTGIGHGSDRAVILGLAGQTP
QTVDPDQADGIIGRITADRMISPPGHPSYHFDPATDLVLDRKTPLTGHANGMAFYAYDASGRLLLKRIYYSIGGGFVVSE
EELQRMKAKGSVTSEGKKVPYPFKNAVEMLKMAAKSGLSIAEMKRVNEETQMSREDLDAGLDAIWGAMKSCIDRGLSQDG
IMPGGLKVRRRARQLHDKLQEQWQQNRPNPLLANDWLSIYAMAVNEENAAGGRVVTAPTNGAAGTLPAVLRYWLHFHPEA
DQPSIRDFLLTAAAVGGIIKTNASISGAEVGCQGEVGSASAMAAAGLCAVMGGTPEQVENAAEIALEHHLGMTCDPVGGL
VQVPCIERNALGAVKAVTAASLAIKGDGIHFVPLDAAIETMRQTGLDMNEKYKETSLGGLAVNVVEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=467, Percent_Identity=47.7516059957173, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1788116, Length=465, Percent_Identity=46.8817204301075, Blast_Score=406, Evalue=1e-114,
Organism=Escherichia coli, GI48994925, Length=465, Percent_Identity=48.1720430107527, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49531; Mature: 49531

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLSVFDLFKIGIGPSSSHTMGPMTAARRFLDEVAGDDWPRPTGAKVARIGASLHGSLAY
CEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEE
TGIGHGSDRAVILGLAGQTPQTVDPDQADGIIGRITADRMISPPGHPSYHFDPATDLVLD
EECCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHEEEE
RKTPLTGHANGMAFYAYDASGRLLLKRIYYSIGGGFVVSEEELQRMKAKGSVTSEGKKVP
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEECHHHHHHHHHCCCCCCCCCCCC
YPFKNAVEMLKMAAKSGLSIAEMKRVNEETQMSREDLDAGLDAIWGAMKSCIDRGLSQDG
CCHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IMPGGLKVRRRARQLHDKLQEQWQQNRPNPLLANDWLSIYAMAVNEENAAGGRVVTAPTN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCEEEEEEEECCCCCCCCEEEECCCC
GAAGTLPAVLRYWLHFHPEADQPSIRDFLLTAAAVGGIIKTNASISGAEVGCQGEVGSAS
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCHH
AMAAAGLCAVMGGTPEQVENAAEIALEHHLGMTCDPVGGLVQVPCIERNALGAVKAVTAA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHH
SLAIKGDGIHFVPLDAAIETMRQTGLDMNEKYKETSLGGLAVNVVEC
HEEEECCCEEEEEHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure
MFLSVFDLFKIGIGPSSSHTMGPMTAARRFLDEVAGDDWPRPTGAKVARIGASLHGSLAY
CEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEE
TGIGHGSDRAVILGLAGQTPQTVDPDQADGIIGRITADRMISPPGHPSYHFDPATDLVLD
EECCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHEEEE
RKTPLTGHANGMAFYAYDASGRLLLKRIYYSIGGGFVVSEEELQRMKAKGSVTSEGKKVP
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEECHHHHHHHHHCCCCCCCCCCCC
YPFKNAVEMLKMAAKSGLSIAEMKRVNEETQMSREDLDAGLDAIWGAMKSCIDRGLSQDG
CCHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IMPGGLKVRRRARQLHDKLQEQWQQNRPNPLLANDWLSIYAMAVNEENAAGGRVVTAPTN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCEEEEEEEECCCCCCCCEEEECCCC
GAAGTLPAVLRYWLHFHPEADQPSIRDFLLTAAAVGGIIKTNASISGAEVGCQGEVGSAS
CCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCCHH
AMAAAGLCAVMGGTPEQVENAAEIALEHHLGMTCDPVGGLVQVPCIERNALGAVKAVTAA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHH
SLAIKGDGIHFVPLDAAIETMRQTGLDMNEKYKETSLGGLAVNVVEC
HEEEECCCEEEEEHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]