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The map label for this gene is rpiA

Identifier: 13470739

GI number: 13470739

Start: 389114

End: 389845

Strand: Reverse

Name: rpiA

Synonym: mll0526

Alternate gene names: 13470739

Gene position: 389845-389114 (Counterclockwise)

Preceding gene: 13470744

Following gene: 13470738

Centisome position: 5.54

GC content: 62.3

Gene sequence:

>732_bases
ATGGATGCAAGACAGTTGAAAGTCGAGGCCGCGCGGGCCGCCCTTGCCCATGTCAGCGACGGCATGCGGCTCGGCATCGG
CACCGGCACGACTGCCGAAGAGTTCGTGCGACTGCTCGCCGACAAGGTCGCCACCGGCATGACCGTCATCGGTGTGCCGA
CGTCCGAGCGCACCGCGGCACTTTGCCGTGAGCTTGGCGTGCCGCTGTCGACATTGGAGGAAACTCCCGAGCTCGATCTT
ACGGTCGACGGCGCCGATGAGGTCGATCCGGAACTGACCTTGATCAAGGGCGGCGGCGGCGCACTGCTGCGCGAAAAGAT
CGTTGCCGCAGCCTCGCAGCGCATGATCGTCATCGCCGACCGCTCGAAGATGGTCGAGACGCTCGGCCGGTTTCCGCTGC
CGATCGAAGTCAACCAGTTCGGCCTGCGCGCCACCGAGATCGCCATAGCCAAGACGGCTGCGGATCTCGGCCTTTCCGGT
CCGATTACATTGAGGATGACGGGAGGCCAGGCTTTTGTTACAGACGGCGGCCATTTTATCCTCGATGCATCTTTTGGCCG
CATTCCGGATACAAGAGCGCTTTCGAATGCTCTCCACGCCATTCCGGGCGTGGTCGAGCATGGTCTTTTCATCGGGCTGG
CGTCAACGGCCATCATCGCCGGCGGCGACGGCATCCAAACCGTCCATGCCGCCCGAAAACCAGGGAGTTCTACCAACCAT
GATGTTGCATAA

Upstream 100 bases:

>100_bases
CAATGATCAAAGGCTTTGAGCACGGTCAAAAGCTTTGACCCGGCCGGCAAAAATGCTAGGAGCCCGAAACACAAGGTTCC
CCGGGGCAGCAAGCAGCAGC

Downstream 100 bases:

>100_bases
CCGGGTTCGCGGCCTTTGCGTCGTTCTGGCGGCTTCAGCCGTTTTCGCCTTCTCGTCGCCGGCGTTTTCGCAGGACGTCA
CGGAGTCGCACCTGAAGGCC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MDARQLKVEAARAALAHVSDGMRLGIGTGTTAEEFVRLLADKVATGMTVIGVPTSERTAALCRELGVPLSTLEETPELDL
TVDGADEVDPELTLIKGGGGALLREKIVAAASQRMIVIADRSKMVETLGRFPLPIEVNQFGLRATEIAIAKTAADLGLSG
PITLRMTGGQAFVTDGGHFILDASFGRIPDTRALSNALHAIPGVVEHGLFIGLASTAIIAGGDGIQTVHAARKPGSSTNH
DVA

Sequences:

>Translated_243_residues
MDARQLKVEAARAALAHVSDGMRLGIGTGTTAEEFVRLLADKVATGMTVIGVPTSERTAALCRELGVPLSTLEETPELDL
TVDGADEVDPELTLIKGGGGALLREKIVAAASQRMIVIADRSKMVETLGRFPLPIEVNQFGLRATEIAIAKTAADLGLSG
PITLRMTGGQAFVTDGGHFILDASFGRIPDTRALSNALHAIPGVVEHGLFIGLASTAIIAGGDGIQTVHAARKPGSSTNH
DVA
>Mature_243_residues
MDARQLKVEAARAALAHVSDGMRLGIGTGTTAEEFVRLLADKVATGMTVIGVPTSERTAALCRELGVPLSTLEETPELDL
TVDGADEVDPELTLIKGGGGALLREKIVAAASQRMIVIADRSKMVETLGRFPLPIEVNQFGLRATEIAIAKTAADLGLSG
PITLRMTGGQAFVTDGGHFILDASFGRIPDTRALSNALHAIPGVVEHGLFIGLASTAIIAGGDGIQTVHAARKPGSSTNH
DVA

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=239, Percent_Identity=39.7489539748954, Blast_Score=144, Evalue=8e-35,
Organism=Escherichia coli, GI1789280, Length=229, Percent_Identity=39.7379912663755, Blast_Score=137, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17551758, Length=228, Percent_Identity=40.3508771929825, Blast_Score=134, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6324669, Length=215, Percent_Identity=35.8139534883721, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281364072, Length=211, Percent_Identity=36.0189573459716, Blast_Score=116, Evalue=1e-26,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_RHILO (Q98ML9)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_102308.1
- ProteinModelPortal:   Q98ML9
- SMR:   Q98ML9
- GeneID:   1224971
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll0526
- NMPDR:   fig|266835.1.peg.413
- HOGENOM:   HBG515603
- OMA:   MVVIADA
- ProtClustDB:   PRK00702
- BRENDA:   5.3.1.6
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 25178; Mature: 25178

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDARQLKVEAARAALAHVSDGMRLGIGTGTTAEEFVRLLADKVATGMTVIGVPTSERTAA
CCCHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHH
LCRELGVPLSTLEETPELDLTVDGADEVDPELTLIKGGGGALLREKIVAAASQRMIVIAD
HHHHHCCCHHHHHCCCCCEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEC
RSKMVETLGRFPLPIEVNQFGLRATEIAIAKTAADLGLSGPITLRMTGGQAFVTDGGHFI
HHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCEEEEECCCEEE
LDASFGRIPDTRALSNALHAIPGVVEHGLFIGLASTAIIAGGDGIQTVHAARKPGSSTNH
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEHHEEEEECCCCHHHHHHHCCCCCCCCC
DVA
CCC
>Mature Secondary Structure
MDARQLKVEAARAALAHVSDGMRLGIGTGTTAEEFVRLLADKVATGMTVIGVPTSERTAA
CCCHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHH
LCRELGVPLSTLEETPELDLTVDGADEVDPELTLIKGGGGALLREKIVAAASQRMIVIAD
HHHHHCCCHHHHHCCCCCEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEC
RSKMVETLGRFPLPIEVNQFGLRATEIAIAKTAADLGLSGPITLRMTGGQAFVTDGGHFI
HHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCEEEEECCCEEE
LDASFGRIPDTRALSNALHAIPGVVEHGLFIGLASTAIIAGGDGIQTVHAARKPGSSTNH
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEHHEEEEECCCCHHHHHHHCCCCCCCCC
DVA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968