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The map label for this gene is pcs

Identifier: 13470725

GI number: 13470725

Start: 374587

End: 375393

Strand: Reverse

Name: pcs

Synonym: mll0506

Alternate gene names: 13470725

Gene position: 375393-374587 (Counterclockwise)

Preceding gene: 13470726

Following gene: 13470724

Centisome position: 5.34

GC content: 60.59

Gene sequence:

>807_bases
ATGGCGGCACGGAAAGCCGCCAAGAAGCTCACGGACCGGATTCCGCGACCGAAGAAGAAGGTCACCTGGCCGCAGGCGAG
GGCGTTCTCCGTCCATCTGCTGACGGCGTCGGGCTCGTTCCTTGCCTTCCTGTCGCTGGTGGCGGCGAGCGAGGAACGCT
GGACGGCAATGTTCTGGTGGCTTGGACTGGCGCTGTTCGTCGACGGCATCGACGGGCCTATCGCCAGGAAGCTCGAGGTC
AAGGAAATCCTGCCGACCTGGTCGGGCGAGCTCCTCGACAACATCATCGACTACGTGACCTATGTGCTGATTCCGGCCTT
CGCGCTCTACCAGCGCGGCTTCATGGGCGAGGGCCTGTCGTTCTTGTCCGCGGCGATCATCGTCGTCTCCAGCGCGATCT
ACTATGCCGACACCGGCATGAAGACGAAGGAGAATTTCTTCAAGGGATTCCCGGTGGTCTGGAACATGGTGGTGTTCACG
CTGTTCGTCATTGAGCCGGGACAATGGGTGTCGTTCGCGGTGGTGGTGGTGGCCGGTATCCTGACGTTCGTCCCGATCAA
TTTCATTCATCCGGTGCGGGTCGTGCGGCTGCGGCCCTTCAATCTCACAATGACCCTTTTGTGGTGTGCTTTCGGCGCGC
TTGCCCTTGCGCAGGCGGCGCTTGCCGCCTTCTACGATCAGATCGGTGTGCTGGGCGCACAGGTCAGCACCTTCATCAAG
ATCGGCATCACCATTACCGGGCTTTACCTGGCCTGCATCGGTGGCATCATGCAGTTCTTTCCAAATCTCGGCGCCAAAAA
GGCCTGA

Upstream 100 bases:

>100_bases
TGCGAGCCTTTGGCCGCAACTGGAATTTTGCCGGCCGCTCGGCCGAAATCTGCAAGCTGGATTGGCGAGGCCCGTGAGCA
AGAACACATCGGCCAGGAAC

Downstream 100 bases:

>100_bases
CCAGCCTCTCCCATAGGAATCCCAGTCCATGTCCAAAGCAATCCGCATCCACGCCCATGGCGGCCCGGAAGTTCTGACCT
ATGAGGACGCCGATCCCGGC

Product: phosphatidylcholine synthase

Products: NA

Alternate protein names: PC synthase; CDP-diglyceride-choline O-phosphatidyltransferase

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MAARKAAKKLTDRIPRPKKKVTWPQARAFSVHLLTASGSFLAFLSLVAASEERWTAMFWWLGLALFVDGIDGPIARKLEV
KEILPTWSGELLDNIIDYVTYVLIPAFALYQRGFMGEGLSFLSAAIIVVSSAIYYADTGMKTKENFFKGFPVVWNMVVFT
LFVIEPGQWVSFAVVVVAGILTFVPINFIHPVRVVRLRPFNLTMTLLWCAFGALALAQAALAAFYDQIGVLGAQVSTFIK
IGITITGLYLACIGGIMQFFPNLGAKKA

Sequences:

>Translated_268_residues
MAARKAAKKLTDRIPRPKKKVTWPQARAFSVHLLTASGSFLAFLSLVAASEERWTAMFWWLGLALFVDGIDGPIARKLEV
KEILPTWSGELLDNIIDYVTYVLIPAFALYQRGFMGEGLSFLSAAIIVVSSAIYYADTGMKTKENFFKGFPVVWNMVVFT
LFVIEPGQWVSFAVVVVAGILTFVPINFIHPVRVVRLRPFNLTMTLLWCAFGALALAQAALAAFYDQIGVLGAQVSTFIK
IGITITGLYLACIGGIMQFFPNLGAKKA
>Mature_267_residues
AARKAAKKLTDRIPRPKKKVTWPQARAFSVHLLTASGSFLAFLSLVAASEERWTAMFWWLGLALFVDGIDGPIARKLEVK
EILPTWSGELLDNIIDYVTYVLIPAFALYQRGFMGEGLSFLSAAIIVVSSAIYYADTGMKTKENFFKGFPVVWNMVVFTL
FVIEPGQWVSFAVVVVAGILTFVPINFIHPVRVVRLRPFNLTMTLLWCAFGALALAQAALAAFYDQIGVLGAQVSTFIKI
GITITGLYLACIGGIMQFFPNLGAKKA

Specific function: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP

COG id: COG1183

COG function: function code I; Phosphatidylserine synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PCS_RHILO (Q98MN3)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_102294.1
- GeneID:   1224957
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll0506
- NMPDR:   fig|266835.1.peg.399
- HOGENOM:   HBG675964
- OMA:   FLHPFRV
- ProtClustDB:   CLSK863002
- BRENDA:   2.7.8.24
- InterPro:   IPR000462

Pfam domain/function: PF01066 CDP-OH_P_transf

EC number: =2.7.8.24

Molecular weight: Translated: 29526; Mature: 29395

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xcae301c)-; HASH(0xd0c0fbc)-; HASH(0xcc6b87c)-; HASH(0xc803be0)-; HASH(0xce7e864)-; HASH(0xd19e31c)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARKAAKKLTDRIPRPKKKVTWPQARAFSVHLLTASGSFLAFLSLVAASEERWTAMFWW
CCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHH
LGLALFVDGIDGPIARKLEVKEILPTWSGELLDNIIDYVTYVLIPAFALYQRGFMGEGLS
HHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
FLSAAIIVVSSAIYYADTGMKTKENFFKGFPVVWNMVVFTLFVIEPGQWVSFAVVVVAGI
HHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LTFVPINFIHPVRVVRLRPFNLTMTLLWCAFGALALAQAALAAFYDQIGVLGAQVSTFIK
HHHHHHHHHCHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGITITGLYLACIGGIMQFFPNLGAKKA
HHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure 
AARKAAKKLTDRIPRPKKKVTWPQARAFSVHLLTASGSFLAFLSLVAASEERWTAMFWW
CHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHH
LGLALFVDGIDGPIARKLEVKEILPTWSGELLDNIIDYVTYVLIPAFALYQRGFMGEGLS
HHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
FLSAAIIVVSSAIYYADTGMKTKENFFKGFPVVWNMVVFTLFVIEPGQWVSFAVVVVAGI
HHHHHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LTFVPINFIHPVRVVRLRPFNLTMTLLWCAFGALALAQAALAAFYDQIGVLGAQVSTFIK
HHHHHHHHHCHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGITITGLYLACIGGIMQFFPNLGAKKA
HHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968