Click here to switch to the map view.

The map label for this gene is qor [H]

Identifier: 13470724

GI number: 13470724

Start: 373581

End: 374558

Strand: Reverse

Name: qor [H]

Synonym: mll0505

Alternate gene names: 13470724

Gene position: 374558-373581 (Counterclockwise)

Preceding gene: 13470725

Following gene: 13470723

Centisome position: 5.32

GC content: 62.78

Gene sequence:

>978_bases
ATGTCCAAAGCAATCCGCATCCACGCCCATGGCGGCCCGGAAGTTCTGACCTATGAGGACGCCGATCCCGGCCAACCGGG
TTCCGGGCAGATCCTGGTCAGGCATACGGCGATCGGCCTCAACTTCATCGATGTCTATCATCGCTCAGGCCTTTATCCGC
CGCCCGGGGGCTTTCCGCTCATTCCGGGCAGCGAAGCCGCCGGCGTGGTGCGGGAGGTCGGTGAGGGCGTCGACTGGCTG
AAGCCAGGCGACCGGATCGCCTATTCGACGAATGTCGGTGCCTATGCCGAGCAACGCGTCATCGCCGCCGGCCTCGTGGT
CAAGATTCCCGATGGCATCAGCGACGAGCAGGCGGCCGCGATGATGCTGAAAGGCATGACCGCCGAATATTTGCTTCGCC
GGACCTTCAAGGTGAAGGCGGGTGACACCATCCTGTTCCATGCCGCGGCCGGCGGCGTTGGCCTCATTCTGGGTCAGTGG
GCGAAACATCTCGGCGCAACCGTCATCGGCACTGCAAGCTCCACCGACAAGATCGAGCTCGCCAAGGCGCACGGTTTCGA
CCATGTCATCAACTACAGGGAGCAGGATTTCGTCGCCGGCGTCGCCGCCATCACCGGCGGCAAAAAATGCGATGTCGTCT
ACGATTCGGTGGGCAATGACACATTCCCGGCCTCGCTCGATTGCTTGAAGCCGCTCGGCATGTTCGTCAGCTTCGGCCAG
TCGTCGGGACCGATCCCGCCCTTCTCGATGTCATTGCTGGCACAGAAGGGCTCGCTGTTCGCCACAAGGCCGACGCTGTT
CGTCTACAACGCAAAACGCGAGGACCTCGACGCCTCCGCGGCCGCGCTGTTCGACGTGGTGCTCAGCGGCGCCGTCAAGA
TCCAGATCAACCAGCGCTATGCGCTGAAGGATGCAGGCAAGGCACATGCCGACCTCGAGGGGCGCAGGACGACAGGGACG
ACCATTCTCATCCCTTAG

Upstream 100 bases:

>100_bases
ACCGGGCTTTACCTGGCCTGCATCGGTGGCATCATGCAGTTCTTTCCAAATCTCGGCGCCAAAAAGGCCTGACCAGCCTC
TCCCATAGGAATCCCAGTCC

Downstream 100 bases:

>100_bases
AGACTGTCTGGAAACTCTGCCCTGGCAGCCATCTGATGGCGTTTTCTGCGCTTCCCCGTTCTACTGCGTCGCAGTAGAAC
TGAGCTCACGGACCCAAATG

Product: quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSKAIRIHAHGGPEVLTYEDADPGQPGSGQILVRHTAIGLNFIDVYHRSGLYPPPGGFPLIPGSEAAGVVREVGEGVDWL
KPGDRIAYSTNVGAYAEQRVIAAGLVVKIPDGISDEQAAAMMLKGMTAEYLLRRTFKVKAGDTILFHAAAGGVGLILGQW
AKHLGATVIGTASSTDKIELAKAHGFDHVINYREQDFVAGVAAITGGKKCDVVYDSVGNDTFPASLDCLKPLGMFVSFGQ
SSGPIPPFSMSLLAQKGSLFATRPTLFVYNAKREDLDASAAALFDVVLSGAVKIQINQRYALKDAGKAHADLEGRRTTGT
TILIP

Sequences:

>Translated_325_residues
MSKAIRIHAHGGPEVLTYEDADPGQPGSGQILVRHTAIGLNFIDVYHRSGLYPPPGGFPLIPGSEAAGVVREVGEGVDWL
KPGDRIAYSTNVGAYAEQRVIAAGLVVKIPDGISDEQAAAMMLKGMTAEYLLRRTFKVKAGDTILFHAAAGGVGLILGQW
AKHLGATVIGTASSTDKIELAKAHGFDHVINYREQDFVAGVAAITGGKKCDVVYDSVGNDTFPASLDCLKPLGMFVSFGQ
SSGPIPPFSMSLLAQKGSLFATRPTLFVYNAKREDLDASAAALFDVVLSGAVKIQINQRYALKDAGKAHADLEGRRTTGT
TILIP
>Mature_324_residues
SKAIRIHAHGGPEVLTYEDADPGQPGSGQILVRHTAIGLNFIDVYHRSGLYPPPGGFPLIPGSEAAGVVREVGEGVDWLK
PGDRIAYSTNVGAYAEQRVIAAGLVVKIPDGISDEQAAAMMLKGMTAEYLLRRTFKVKAGDTILFHAAAGGVGLILGQWA
KHLGATVIGTASSTDKIELAKAHGFDHVINYREQDFVAGVAAITGGKKCDVVYDSVGNDTFPASLDCLKPLGMFVSFGQS
SGPIPPFSMSLLAQKGSLFATRPTLFVYNAKREDLDASAAALFDVVLSGAVKIQINQRYALKDAGKAHADLEGRRTTGTT
ILIP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=327, Percent_Identity=31.8042813455657, Blast_Score=145, Evalue=3e-35,
Organism=Homo sapiens, GI13236495, Length=327, Percent_Identity=31.8042813455657, Blast_Score=145, Evalue=3e-35,
Organism=Homo sapiens, GI18379349, Length=312, Percent_Identity=29.8076923076923, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI194239676, Length=327, Percent_Identity=30.2752293577982, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=30.6060606060606, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=30.6060606060606, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI24308257, Length=244, Percent_Identity=34.0163934426229, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI28557745, Length=283, Percent_Identity=28.6219081272085, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI197927207, Length=188, Percent_Identity=29.7872340425532, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1790485, Length=328, Percent_Identity=50.3048780487805, Blast_Score=313, Evalue=1e-86,
Organism=Escherichia coli, GI87081918, Length=277, Percent_Identity=28.5198555956679, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI226510941, Length=268, Percent_Identity=27.6119402985075, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=310, Percent_Identity=27.741935483871, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17556000, Length=209, Percent_Identity=32.0574162679426, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319520, Length=324, Percent_Identity=39.1975308641975, Blast_Score=216, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6324486, Length=257, Percent_Identity=26.4591439688716, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323729, Length=253, Percent_Identity=25.296442687747, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323961, Length=270, Percent_Identity=25.9259259259259, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34318; Mature: 34186

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKAIRIHAHGGPEVLTYEDADPGQPGSGQILVRHTAIGLNFIDVYHRSGLYPPPGGFPL
CCCEEEEEECCCCEEEEECCCCCCCCCCCCEEEEEEEECCHHEEHHHHCCCCCCCCCCCC
IPGSEAAGVVREVGEGVDWLKPGDRIAYSTNVGAYAEQRVIAAGLVVKIPDGISDEQAAA
CCCCHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHEEEEECEEEECCCCCCHHHHHH
MMLKGMTAEYLLRRTFKVKAGDTILFHAAAGGVGLILGQWAKHLGATVIGTASSTDKIEL
HHHHCCCHHHHHHHHEEEECCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCCEEE
AKAHGFDHVINYREQDFVAGVAAITGGKKCDVVYDSVGNDTFPASLDCLKPLGMFVSFGQ
EHHCCCHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCC
SSGPIPPFSMSLLAQKGSLFATRPTLFVYNAKREDLDASAAALFDVVLSGAVKIQINQRY
CCCCCCCHHHHHHHCCCCEEEECCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEECCEE
ALKDAGKAHADLEGRRTTGTTILIP
EECCCCCCCCCCCCCCCCCCEEEEC
>Mature Secondary Structure 
SKAIRIHAHGGPEVLTYEDADPGQPGSGQILVRHTAIGLNFIDVYHRSGLYPPPGGFPL
CCEEEEEECCCCEEEEECCCCCCCCCCCCEEEEEEEECCHHEEHHHHCCCCCCCCCCCC
IPGSEAAGVVREVGEGVDWLKPGDRIAYSTNVGAYAEQRVIAAGLVVKIPDGISDEQAAA
CCCCHHHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHEEEEECEEEECCCCCCHHHHHH
MMLKGMTAEYLLRRTFKVKAGDTILFHAAAGGVGLILGQWAKHLGATVIGTASSTDKIEL
HHHHCCCHHHHHHHHEEEECCCEEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCCEEE
AKAHGFDHVINYREQDFVAGVAAITGGKKCDVVYDSVGNDTFPASLDCLKPLGMFVSFGQ
EHHCCCHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCC
SSGPIPPFSMSLLAQKGSLFATRPTLFVYNAKREDLDASAAALFDVVLSGAVKIQINQRY
CCCCCCCHHHHHHHCCCCEEEECCEEEEEECCCCCCCHHHHHHHHHHHCCEEEEEECCEE
ALKDAGKAHADLEGRRTTGTTILIP
EECCCCCCCCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]