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The map label for this gene is cfa [H]

Identifier: 13470609

GI number: 13470609

Start: 262402

End: 263538

Strand: Reverse

Name: cfa [H]

Synonym: mll0368

Alternate gene names: 13470609

Gene position: 263538-262402 (Counterclockwise)

Preceding gene: 13470614

Following gene: 13470606

Centisome position: 3.75

GC content: 62.8

Gene sequence:

>1137_bases
ATGAACCTGCCGCGCGGTTCGCTCAAGGTCAGGATGCCGGATGGCCGCGCCGTTTTGGTTGGCGGCAAGGGACCCGGCCC
GGACGCCGAGCTGGTGCTCAAGAACTGGCGCCTGCCAGGCCGCGCCTTTTCCGGCGGCACGATCGGCGTTGCCGAATCCT
ACATGGACGGCGATTGGGAAAGCCCTGACGTCACCAGCTTCCTGGAGTTGTTCGTGGTCAATTCGGCGATCGGCGAACGC
GTCGCCGGCGGCGCCAGCTGGCTCATAAACACCGTCCAGCGCATCCGCCACTGGTTCAACGAGAACACACGCACCGGTTC
GAAGCGCAACATCTCCGCGCATTACGATCTCGGCAACGCCTTCTACAGGGAGTGGCTCGATCCGAGCATGACCTATTCCT
CGGCGCTCTACGCGAATGGCGCCAACGACCTCGAAAGCGCCCAGGCCGCCAAATATCGGGCGCTGGCCAGGGATACGGGT
ATCGGCGGAAAGGATCATGTGCTGGAGATCGGCTGCGGCTGGGGCGGTTTTGCCGAATTCGCGGCACGCGAGATCGGCTG
CCGCGTGACGGGGCTGACGATCAGCCGCGAACAGCACGATTTCGCCAAGGCACGCATCGCCAAGGCCGGGCTTGCCGACA
AGGTCGACATCAAGCTGCAGGATTACCGCGACGAAACAGGGACTTACGACCGCATCGCCTCGATCGAGATGTTCGAAGCG
GTCGGCGAGAAATATTGGCCGGTGTTCTTCTCGAAGATGAAGTCCTGCCTGAGGCCCGGCGGCACTGCGGGCCTGCAGAT
CATCACCATCAACGAGGCCGCCTACGACACCTATCGCGCCCGGCCGGACTTCATTCAGCGCTACGTGTTTCCGGGCGGCA
TGCTGCCGACACCGTCGATCCTGAAGTCGCTCGGCAAAGACCATGGCCTCGCGCATCTGCGTGAGCGCGTGTTTCCCGAT
GACTATGCGCGCACGCTCGCCGAATGGCGCAACCGCTTCTGGGGATCCTGGGAGAAGATCGTGCCGCTCGGCTTCGACGA
TCGCTTCAAGAAGCTCTGGGAGTTCTACCTGCACTATTGCGAGGCCGGTTTCCGCGCCAGCTACATCGATGTGCGGCAAG
TGGTCTACAAGGCGTAA

Upstream 100 bases:

>100_bases
TAGCGTAGCGTCGGGCGAAGCGGTCAGGCTCGACGAGTTCAATTTCGCCGAGATCGTCAAGGGCCTGCCGGCCAAGGCGC
GCATGGTGCTGTCGGCGGCG

Downstream 100 bases:

>100_bases
GCCGGCACACTCATCGATCTCACCGCCAGTGGCCAGCCTTGTTGGGATCCGCTGACTTAAATTGTGAGGTACGCCCAAGG
CGGCCGATCGCAACCTCTTG

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MNLPRGSLKVRMPDGRAVLVGGKGPGPDAELVLKNWRLPGRAFSGGTIGVAESYMDGDWESPDVTSFLELFVVNSAIGER
VAGGASWLINTVQRIRHWFNENTRTGSKRNISAHYDLGNAFYREWLDPSMTYSSALYANGANDLESAQAAKYRALARDTG
IGGKDHVLEIGCGWGGFAEFAAREIGCRVTGLTISREQHDFAKARIAKAGLADKVDIKLQDYRDETGTYDRIASIEMFEA
VGEKYWPVFFSKMKSCLRPGGTAGLQIITINEAAYDTYRARPDFIQRYVFPGGMLPTPSILKSLGKDHGLAHLRERVFPD
DYARTLAEWRNRFWGSWEKIVPLGFDDRFKKLWEFYLHYCEAGFRASYIDVRQVVYKA

Sequences:

>Translated_378_residues
MNLPRGSLKVRMPDGRAVLVGGKGPGPDAELVLKNWRLPGRAFSGGTIGVAESYMDGDWESPDVTSFLELFVVNSAIGER
VAGGASWLINTVQRIRHWFNENTRTGSKRNISAHYDLGNAFYREWLDPSMTYSSALYANGANDLESAQAAKYRALARDTG
IGGKDHVLEIGCGWGGFAEFAAREIGCRVTGLTISREQHDFAKARIAKAGLADKVDIKLQDYRDETGTYDRIASIEMFEA
VGEKYWPVFFSKMKSCLRPGGTAGLQIITINEAAYDTYRARPDFIQRYVFPGGMLPTPSILKSLGKDHGLAHLRERVFPD
DYARTLAEWRNRFWGSWEKIVPLGFDDRFKKLWEFYLHYCEAGFRASYIDVRQVVYKA
>Mature_378_residues
MNLPRGSLKVRMPDGRAVLVGGKGPGPDAELVLKNWRLPGRAFSGGTIGVAESYMDGDWESPDVTSFLELFVVNSAIGER
VAGGASWLINTVQRIRHWFNENTRTGSKRNISAHYDLGNAFYREWLDPSMTYSSALYANGANDLESAQAAKYRALARDTG
IGGKDHVLEIGCGWGGFAEFAAREIGCRVTGLTISREQHDFAKARIAKAGLADKVDIKLQDYRDETGTYDRIASIEMFEA
VGEKYWPVFFSKMKSCLRPGGTAGLQIITINEAAYDTYRARPDFIQRYVFPGGMLPTPSILKSLGKDHGLAHLRERVFPD
DYARTLAEWRNRFWGSWEKIVPLGFDDRFKKLWEFYLHYCEAGFRASYIDVRQVVYKA

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=368, Percent_Identity=33.695652173913, Blast_Score=179, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI133904226, Length=361, Percent_Identity=37.9501385041551, Blast_Score=234, Evalue=4e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 42459; Mature: 42459

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPRGSLKVRMPDGRAVLVGGKGPGPDAELVLKNWRLPGRAFSGGTIGVAESYMDGDWE
CCCCCCCEEEECCCCCEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCC
SPDVTSFLELFVVNSAIGERVAGGASWLINTVQRIRHWFNENTRTGSKRNISAHYDLGNA
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHH
FYREWLDPSMTYSSALYANGANDLESAQAAKYRALARDTGIGGKDHVLEIGCGWGGFAEF
HHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHH
AAREIGCRVTGLTISREQHDFAKARIAKAGLADKVDIKLQDYRDETGTYDRIASIEMFEA
HHHHHCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHH
VGEKYWPVFFSKMKSCLRPGGTAGLQIITINEAAYDTYRARPDFIQRYVFPGGMLPTPSI
HCHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHCCCHHHHHHHHCCCCCCCCHHH
LKSLGKDHGLAHLRERVFPDDYARTLAEWRNRFWGSWEKIVPLGFDDRFKKLWEFYLHYC
HHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHEEECCCCHHHHHHHHHHHHHH
EAGFRASYIDVRQVVYKA
HCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNLPRGSLKVRMPDGRAVLVGGKGPGPDAELVLKNWRLPGRAFSGGTIGVAESYMDGDWE
CCCCCCCEEEECCCCCEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCC
SPDVTSFLELFVVNSAIGERVAGGASWLINTVQRIRHWFNENTRTGSKRNISAHYDLGNA
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCHHH
FYREWLDPSMTYSSALYANGANDLESAQAAKYRALARDTGIGGKDHVLEIGCGWGGFAEF
HHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHH
AAREIGCRVTGLTISREQHDFAKARIAKAGLADKVDIKLQDYRDETGTYDRIASIEMFEA
HHHHHCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHH
VGEKYWPVFFSKMKSCLRPGGTAGLQIITINEAAYDTYRARPDFIQRYVFPGGMLPTPSI
HCHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHCCCHHHHHHHHCCCCCCCCHHH
LKSLGKDHGLAHLRERVFPDDYARTLAEWRNRFWGSWEKIVPLGFDDRFKKLWEFYLHYC
HHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHEEECCCCHHHHHHHHHHHHHH
EAGFRASYIDVRQVVYKA
HCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]