Click here to switch to the map view.

The map label for this gene is acoC [H]

Identifier: 13470437

GI number: 13470437

Start: 101864

End: 102868

Strand: Direct

Name: acoC [H]

Synonym: mlr0145

Alternate gene names: 13470437

Gene position: 101864-102868 (Clockwise)

Preceding gene: 13470432

Following gene: 13470438

Centisome position: 1.45

GC content: 63.08

Gene sequence:

>1005_bases
ATGCTGATATCGATCCTGTCATGGCTGCTGGCCGTGCTGTTCCTGCTGGCGGTCCTGGGGATCGCCTGCCTGGCGCTGGC
GACGCTTTGGATCGCCATGAAAGCCCAAGCACTGGTGCCGCCGGTCGGAAAATTCATCGAGATCGACGGCAACCGCATCC
ACTATGTCGATGTGGGCGAGGGGCGGCCGATCGTCTTCCTGCACGGGCTTGGCGCGCAACTCCATCACTTCCGGCGCACT
TTGTTCGGACATTTCGGCCCGGGTTATCGCCTGATCGCGCTCGATCGTCCGGGATCGGGCTATTCGACGCGCGCGAGCGG
CACCACCGGCCGCTTGCCTGAACAGGCGGCGCTGGTGCGCCGCTTCATCGAAAAATTGCAACTGGAAAGGCCGCTGGTCG
TGGGCCACTCGCTGGGTGGCGCCGTCACATTGACCCTGGCCGTGGAACATCCCGAGGCAATTTCGGGCATCGCCTTGCTG
GCGCCGCTGACGCATCTGGAAACCAGGGCGCGGCAAAGATTTGACCTGCTGTACATCCCCTCCCGCGTGCAGCGCTGGAT
CATGGCCTATACCGTGGCGATACCCCTGAGCCTGCGCTATGCGCGGCCGACAATGGAATTCATCTTCGCGCCGCAGGCTT
TTCCGACGGACTACATGGTCGAAGGCGGCGGCTGGCTCGGGCTGCGACCAGTCCATTTCCAGGCGACATCGGCCGATGTC
GTGGCCGTCGAAGAGGATCTCGGCCGCATCGAGCAGCGCTACGGCGAGATTGTCATGCCTGCCGGCATCCTCTTCGGAAC
CGCCGACCGTGTCATCGACATCCGCATCCATGGCGAGCCGATGCGAGGCAAGATCGCGGGGCTCGATTTTGAACCCGTCG
ACGGCGTCGGCCATATGCCGCAGTTCGTCGAACCCAAGCGGGTGATTGGCTTCATCGAGCGGATTGCCGTCCGCGCGTTT
CCATCACCGCAGCCTCACGACAATTTCAATGAACCAACCGGCTGA

Upstream 100 bases:

>100_bases
AGGCGGTGAACAATCCATGCCTGGACGCGCCCGTTTCGAAGCGAGGTTGCAGCATGACCGGATGCGGGTAAGCTCAAACG
GGTTCTGGTCCGGGTGAACA

Downstream 100 bases:

>100_bases
CTGCCGGGTTTACCCCGTGTCGCACCCCAAGGCGACCAAGACACGGAGTAATGCAATGTACAGGAGATTTCTTGCAGCAT
CGGTTCTGACGATCGGTCTC

Product: lactone-specific esterase

Products: NA

Alternate protein names: Acetoin dehydrogenase E2 component; Dihydrolipoamide acetyltransferase component of acetoin cleaving system; Fast-migrating protein; FMP [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MLISILSWLLAVLFLLAVLGIACLALATLWIAMKAQALVPPVGKFIEIDGNRIHYVDVGEGRPIVFLHGLGAQLHHFRRT
LFGHFGPGYRLIALDRPGSGYSTRASGTTGRLPEQAALVRRFIEKLQLERPLVVGHSLGGAVTLTLAVEHPEAISGIALL
APLTHLETRARQRFDLLYIPSRVQRWIMAYTVAIPLSLRYARPTMEFIFAPQAFPTDYMVEGGGWLGLRPVHFQATSADV
VAVEEDLGRIEQRYGEIVMPAGILFGTADRVIDIRIHGEPMRGKIAGLDFEPVDGVGHMPQFVEPKRVIGFIERIAVRAF
PSPQPHDNFNEPTG

Sequences:

>Translated_334_residues
MLISILSWLLAVLFLLAVLGIACLALATLWIAMKAQALVPPVGKFIEIDGNRIHYVDVGEGRPIVFLHGLGAQLHHFRRT
LFGHFGPGYRLIALDRPGSGYSTRASGTTGRLPEQAALVRRFIEKLQLERPLVVGHSLGGAVTLTLAVEHPEAISGIALL
APLTHLETRARQRFDLLYIPSRVQRWIMAYTVAIPLSLRYARPTMEFIFAPQAFPTDYMVEGGGWLGLRPVHFQATSADV
VAVEEDLGRIEQRYGEIVMPAGILFGTADRVIDIRIHGEPMRGKIAGLDFEPVDGVGHMPQFVEPKRVIGFIERIAVRAF
PSPQPHDNFNEPTG
>Mature_334_residues
MLISILSWLLAVLFLLAVLGIACLALATLWIAMKAQALVPPVGKFIEIDGNRIHYVDVGEGRPIVFLHGLGAQLHHFRRT
LFGHFGPGYRLIALDRPGSGYSTRASGTTGRLPEQAALVRRFIEKLQLERPLVVGHSLGGAVTLTLAVEHPEAISGIALL
APLTHLETRARQRFDLLYIPSRVQRWIMAYTVAIPLSLRYARPTMEFIFAPQAFPTDYMVEGGGWLGLRPVHFQATSADV
VAVEEDLGRIEQRYGEIVMPAGILFGTADRVIDIRIHGEPMRGKIAGLDFEPVDGVGHMPQFVEPKRVIGFIERIAVRAF
PSPQPHDNFNEPTG

Specific function: Dihydrolipoamide acetyltransferase involved in acetoin catabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 lipoyl-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003016
- InterPro:   IPR000073
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF00364 Biotin_lipoyl [H]

EC number: =2.3.1.12 [H]

Molecular weight: Translated: 36856; Mature: 36856

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLISILSWLLAVLFLLAVLGIACLALATLWIAMKAQALVPPVGKFIEIDGNRIHYVDVGE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCC
GRPIVFLHGLGAQLHHFRRTLFGHFGPGYRLIALDRPGSGYSTRASGTTGRLPEQAALVR
CCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHH
RFIEKLQLERPLVVGHSLGGAVTLTLAVEHPEAISGIALLAPLTHLETRARQRFDLLYIP
HHHHHHCCCCCEEEEECCCCEEEEEEEECCCCHHCCHHHHHHHHHHHHHHHHHCEEEECC
SRVQRWIMAYTVAIPLSLRYARPTMEFIFAPQAFPTDYMVEGGGWLGLRPVHFQATSADV
HHHHHHHHHHHHHHHEEEEECCCCEEEEECCCCCCCCEEEECCCEECCEEEEEECCCCCE
VAVEEDLGRIEQRYGEIVMPAGILFGTADRVIDIRIHGEPMRGKIAGLDFEPVDGVGHMP
EEEHHHHHHHHHHHCCEEECCHHEEECCCEEEEEEEECCCCCCEEECCCCCCCCCCCCCC
QFVEPKRVIGFIERIAVRAFPSPQPHDNFNEPTG
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLISILSWLLAVLFLLAVLGIACLALATLWIAMKAQALVPPVGKFIEIDGNRIHYVDVGE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCC
GRPIVFLHGLGAQLHHFRRTLFGHFGPGYRLIALDRPGSGYSTRASGTTGRLPEQAALVR
CCCEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHH
RFIEKLQLERPLVVGHSLGGAVTLTLAVEHPEAISGIALLAPLTHLETRARQRFDLLYIP
HHHHHHCCCCCEEEEECCCCEEEEEEEECCCCHHCCHHHHHHHHHHHHHHHHHCEEEECC
SRVQRWIMAYTVAIPLSLRYARPTMEFIFAPQAFPTDYMVEGGGWLGLRPVHFQATSADV
HHHHHHHHHHHHHHHEEEEECCCCEEEEECCCCCCCCEEEECCCEECCEEEEEECCCCCE
VAVEEDLGRIEQRYGEIVMPAGILFGTADRVIDIRIHGEPMRGKIAGLDFEPVDGVGHMP
EEEHHHHHHHHHHHCCEEECCHHEEECCCEEEEEEEECCCCCCEEECCCCCCCCCCCCCC
QFVEPKRVIGFIERIAVRAFPSPQPHDNFNEPTG
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2061286 [H]