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The map label for this gene is tas [H]

Identifier: 13470402

GI number: 13470402

Start: 69673

End: 70740

Strand: Direct

Name: tas [H]

Synonym: mlr0100

Alternate gene names: 13470402

Gene position: 69673-70740 (Clockwise)

Preceding gene: 13470401

Following gene: 13470403

Centisome position: 0.99

GC content: 61.61

Gene sequence:

>1068_bases
ATGCACAAACGCCGTCTCGGTCGGACCGATCTTCTTGTTACCCAGATCTGCCTTGGTTCGATGACCTGGGGCCAGCAGAA
CACCGAGGCCGAAGGCCACGCGCAGATGGATCTGGCTTTTTCGCGCGGCGTCAATTTCATCGACACCGCCGAGCTCTATC
CGATCCCGCCCAAGGCGGAGACGCAGGGGCGGACGGAGAAGATCATTGGCAGCTGGATGAAGGCCAAGGGCAATCGCGAC
AAGGTGATCCTTGCCTCCAAGGTCGTCGGCCGCACCGCCAACAGCTGGTTTCGCGGCGACAGGCCGTCGCAATTGGTACG
TGCCGATATTTTTGACGCCGTCGACAAATCCCTGGCCAAACTCGGCACGGACTATCTCGACCTCTACCAGATCCACTGGC
CGGAACGGGATATCCCCTGGGGTGCCAACCCGACGCGCATCGGCGCCGTGGCGCGGCGCGCCGATGCCGACGGCGCACCG
GCCAACGAAACGCCGATCGCTGAGACGCTTGGCGTCTTCGATGAGTTGGTGAAGGCAGGAAAGATCCGCCATTTCGGCCT
GTCGAACGAAAGTTCCTGGGGCGTCATGCGGTTTCTTGCCGAGGCCGACAAAGGCGTTGGCCCGCGCGTAGCGTCGATCC
AGAACGCCTACAATCTCGTCAACCGCACCTTCGAGGTGAATCTTGCCGAGGTCTGCGAGCGCGAACAGGTGTCGTTGCTG
CCATATTCGCCGTTGGCGCAGGGCTACCTGACCGGCAAATACGACCATGGCGCCCGACCGCAGGGCTCGCGCTCGCAATT
GTTCAATCGCGGCCAGCGTTACGAGACGCCGAATGCAGCCGAAGTGCTGCTCGAATACAATGAACTGGCGCGCTCCTTTG
GCATGGAGCCGGCGCTGTTTGCCAATGCCTATGTATCGAGCCGGCCGTTCGTCACCTCCAACATCATCGGCGCGACGACC
ATTCCACAGCTCGAAATGGCGTTGTCTTCGGTGGATGTCGTCTGGACAGAGGAGATGCAGAAGGCGGTGGACGCGATCCA
CCAGCGGGTCGGCAATCCCTGTCCCTGA

Upstream 100 bases:

>100_bases
TTCACGCAAAAGTCGGCCTGGTGAGGGTTGGAGAGCGCCGTGGCTTTCCCTATACATGCGTCTCCCTCCCGCGCAGACTT
TCCCTCCGGAGCAGAATTCC

Downstream 100 bases:

>100_bases
TCGGCGTGAATTATCAAGGAACAACGGAGGGGTGGAGACGATGGTGGATTTTCCGATCGAGGCCGTGCGCGGACAATTTC
CAGCGCTTTCCCTGACCGAC

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MHKRRLGRTDLLVTQICLGSMTWGQQNTEAEGHAQMDLAFSRGVNFIDTAELYPIPPKAETQGRTEKIIGSWMKAKGNRD
KVILASKVVGRTANSWFRGDRPSQLVRADIFDAVDKSLAKLGTDYLDLYQIHWPERDIPWGANPTRIGAVARRADADGAP
ANETPIAETLGVFDELVKAGKIRHFGLSNESSWGVMRFLAEADKGVGPRVASIQNAYNLVNRTFEVNLAEVCEREQVSLL
PYSPLAQGYLTGKYDHGARPQGSRSQLFNRGQRYETPNAAEVLLEYNELARSFGMEPALFANAYVSSRPFVTSNIIGATT
IPQLEMALSSVDVVWTEEMQKAVDAIHQRVGNPCP

Sequences:

>Translated_355_residues
MHKRRLGRTDLLVTQICLGSMTWGQQNTEAEGHAQMDLAFSRGVNFIDTAELYPIPPKAETQGRTEKIIGSWMKAKGNRD
KVILASKVVGRTANSWFRGDRPSQLVRADIFDAVDKSLAKLGTDYLDLYQIHWPERDIPWGANPTRIGAVARRADADGAP
ANETPIAETLGVFDELVKAGKIRHFGLSNESSWGVMRFLAEADKGVGPRVASIQNAYNLVNRTFEVNLAEVCEREQVSLL
PYSPLAQGYLTGKYDHGARPQGSRSQLFNRGQRYETPNAAEVLLEYNELARSFGMEPALFANAYVSSRPFVTSNIIGATT
IPQLEMALSSVDVVWTEEMQKAVDAIHQRVGNPCP
>Mature_355_residues
MHKRRLGRTDLLVTQICLGSMTWGQQNTEAEGHAQMDLAFSRGVNFIDTAELYPIPPKAETQGRTEKIIGSWMKAKGNRD
KVILASKVVGRTANSWFRGDRPSQLVRADIFDAVDKSLAKLGTDYLDLYQIHWPERDIPWGANPTRIGAVARRADADGAP
ANETPIAETLGVFDELVKAGKIRHFGLSNESSWGVMRFLAEADKGVGPRVASIQNAYNLVNRTFEVNLAEVCEREQVSLL
PYSPLAQGYLTGKYDHGARPQGSRSQLFNRGQRYETPNAAEVLLEYNELARSFGMEPALFANAYVSSRPFVTSNIIGATT
IPQLEMALSSVDVVWTEEMQKAVDAIHQRVGNPCP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=348, Percent_Identity=27.0114942528736, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4504825, Length=345, Percent_Identity=26.9565217391304, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI27436962, Length=346, Percent_Identity=27.1676300578035, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI27436964, Length=346, Percent_Identity=27.1676300578035, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI27436966, Length=346, Percent_Identity=27.1676300578035, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI223718702, Length=252, Percent_Identity=27.3809523809524, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI41327764, Length=370, Percent_Identity=27.5675675675676, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1789199, Length=356, Percent_Identity=44.9438202247191, Blast_Score=309, Evalue=2e-85,
Organism=Escherichia coli, GI87081735, Length=352, Percent_Identity=29.8295454545455, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1788070, Length=363, Percent_Identity=27.5482093663912, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1789375, Length=337, Percent_Identity=26.7062314540059, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1788081, Length=275, Percent_Identity=29.0909090909091, Blast_Score=80, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6325169, Length=361, Percent_Identity=23.8227146814404, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 39294; Mature: 39294

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKRRLGRTDLLVTQICLGSMTWGQQNTEAEGHAQMDLAFSRGVNFIDTAELYPIPPKAE
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEECCCCCCCCCCCC
TQGRTEKIIGSWMKAKGNRDKVILASKVVGRTANSWFRGDRPSQLVRADIFDAVDKSLAK
CCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LGTDYLDLYQIHWPERDIPWGANPTRIGAVARRADADGAPANETPIAETLGVFDELVKAG
HCCHHHHHHEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHC
KIRHFGLSNESSWGVMRFLAEADKGVGPRVASIQNAYNLVNRTFEVNLAEVCEREQVSLL
CEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
PYSPLAQGYLTGKYDHGARPQGSRSQLFNRGQRYETPNAAEVLLEYNELARSFGMEPALF
CCCHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHH
ANAYVSSRPFVTSNIIGATTIPQLEMALSSVDVVWTEEMQKAVDAIHQRVGNPCP
HHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHKRRLGRTDLLVTQICLGSMTWGQQNTEAEGHAQMDLAFSRGVNFIDTAELYPIPPKAE
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEECCCCCCCCCCCC
TQGRTEKIIGSWMKAKGNRDKVILASKVVGRTANSWFRGDRPSQLVRADIFDAVDKSLAK
CCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LGTDYLDLYQIHWPERDIPWGANPTRIGAVARRADADGAPANETPIAETLGVFDELVKAG
HCCHHHHHHEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHC
KIRHFGLSNESSWGVMRFLAEADKGVGPRVASIQNAYNLVNRTFEVNLAEVCEREQVSLL
CEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCC
PYSPLAQGYLTGKYDHGARPQGSRSQLFNRGQRYETPNAAEVLLEYNELARSFGMEPALF
CCCHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHH
ANAYVSSRPFVTSNIIGATTIPQLEMALSSVDVVWTEEMQKAVDAIHQRVGNPCP
HHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]