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The map label for this gene is livK [C]

Identifier: 13470390

GI number: 13470390

Start: 59059

End: 60126

Strand: Reverse

Name: livK [C]

Synonym: mll0086

Alternate gene names: 13470390

Gene position: 60126-59059 (Counterclockwise)

Preceding gene: 13470398

Following gene: 13470389

Centisome position: 0.85

GC content: 67.04

Gene sequence:

>1068_bases
ATGCGACCCGGGGCAACGATATCGGCCGCGCTGGCCTGGCTGTTCCTGGCCGGCGCCGCTAGCGCCCAGACGCTGACGAT
CGGCGTTGCTGCTCCGTTGTCGGGACCGTCGGCCATCCTCGGCAAGCAGATCGAGGCCGGTGCAGCGCTGGCGGCGCAAG
CAGACGGCGTCGAACTCAAGACCGAGGATGATGCCTGCACCGCCGATGGCGGGGCAGCCGCGGCCAGGGTTTTTGCTGCG
GCCAAGGTCAGTGTCGTGATCGGCTTCCTCTGCACCGAAGCCATCGAGGCGGCGATGCCGATCCTCAAGGACGCCAATAT
CCCGGTCATCACCGTCGGCGTGCGTACCGAAAGCCTCACCGACCGCCGCGCCAAGACCGGCTGGCCGGTCTATCGCCTGG
GGCCGCGCGGCGACGATGAACGCAACGCCGTCGCCTCCACCCTCACCCACCTGTGGCAGAAGGAGCTGTTCGCCATCATC
GATGACGGCACCATCTATGGCCGCGAGATGGCGGAAACATTTCGCGCGGCGGCCGAGCAAGCGGCGCTGAAACCGGTGTT
CGTCGACACGTTCCGGCCGCAGCTCGACAACCAGATAGGGATGATCGGGCGGCTGAAGAAGGCCGGCGCCACGCATGTCT
TTGCCGGCGGCGACGGTGACGACATCGCGATTATGGGCCGCGATGCCGCGCAGCTGCAGGCCGGCATCGTCTTTGCCGGC
GGCGAAAATCTGCGCACGCCGCCCGGCGACGTGCCCTATGCGACAGGCACGCTGATGATCGCGCCGCCCGAATGGGCCGA
TGTCGCCGACGCAAAGGTGCTGGAAAGCTTCTCCGTGCAGAAAATCGTGCCGGACGGCTATACGCTGCCGGCCTTTGCGG
CGGTCGAGATCGCCAAGGCCGCATCGACCTTGTCCCCGGGCAAGCCGCTGACCGAAGTGCTGAGCGGGCATGATTTCGCC
ACGGCGATCGGCCCGGTCCGCTTCGACGCCAAGGGCGACCTCAGCCAGAGCCCCTACCGCGTCTTCCGCTTCGACGGCGC
GCGCTTCGTGCCTTTGGAAAGCAATTGA

Upstream 100 bases:

>100_bases
CCCGAATTCGCGTGTTGCACCAAGGCCGGGCAGCCTTTAGGTCTTGGCGGAATTGGCGCTCGCGCTGTTATCGCGGGCTT
GGGAGGAACTCTTCGGCAGA

Downstream 100 bases:

>100_bases
TGTTCCACACCGGTCCGCGCAATCTGATCACCGACGTTGCCGGCCTGCGCGTCGGCAATTCTTCCGATGCCCGGCTGAAA
TCCGGCGTGACGACTATCCT

Product: amino acid binding protein

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MRPGATISAALAWLFLAGAASAQTLTIGVAAPLSGPSAILGKQIEAGAALAAQADGVELKTEDDACTADGGAAAARVFAA
AKVSVVIGFLCTEAIEAAMPILKDANIPVITVGVRTESLTDRRAKTGWPVYRLGPRGDDERNAVASTLTHLWQKELFAII
DDGTIYGREMAETFRAAAEQAALKPVFVDTFRPQLDNQIGMIGRLKKAGATHVFAGGDGDDIAIMGRDAAQLQAGIVFAG
GENLRTPPGDVPYATGTLMIAPPEWADVADAKVLESFSVQKIVPDGYTLPAFAAVEIAKAASTLSPGKPLTEVLSGHDFA
TAIGPVRFDAKGDLSQSPYRVFRFDGARFVPLESN

Sequences:

>Translated_355_residues
MRPGATISAALAWLFLAGAASAQTLTIGVAAPLSGPSAILGKQIEAGAALAAQADGVELKTEDDACTADGGAAAARVFAA
AKVSVVIGFLCTEAIEAAMPILKDANIPVITVGVRTESLTDRRAKTGWPVYRLGPRGDDERNAVASTLTHLWQKELFAII
DDGTIYGREMAETFRAAAEQAALKPVFVDTFRPQLDNQIGMIGRLKKAGATHVFAGGDGDDIAIMGRDAAQLQAGIVFAG
GENLRTPPGDVPYATGTLMIAPPEWADVADAKVLESFSVQKIVPDGYTLPAFAAVEIAKAASTLSPGKPLTEVLSGHDFA
TAIGPVRFDAKGDLSQSPYRVFRFDGARFVPLESN
>Mature_355_residues
MRPGATISAALAWLFLAGAASAQTLTIGVAAPLSGPSAILGKQIEAGAALAAQADGVELKTEDDACTADGGAAAARVFAA
AKVSVVIGFLCTEAIEAAMPILKDANIPVITVGVRTESLTDRRAKTGWPVYRLGPRGDDERNAVASTLTHLWQKELFAII
DDGTIYGREMAETFRAAAEQAALKPVFVDTFRPQLDNQIGMIGRLKKAGATHVFAGGDGDDIAIMGRDAAQLQAGIVFAG
GENLRTPPGDVPYATGTLMIAPPEWADVADAKVLESFSVQKIVPDGYTLPAFAAVEIAKAASTLSPGKPLTEVLSGHDFA
TAIGPVRFDAKGDLSQSPYRVFRFDGARFVPLESN

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Escherichia coli, GI1789867, Length=365, Percent_Identity=27.3972602739726, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI48994941, Length=359, Percent_Identity=23.9554317548747, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 36993; Mature: 36993

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPGATISAALAWLFLAGAASAQTLTIGVAAPLSGPSAILGKQIEAGAALAAQADGVELK
CCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHCCHHHCCCEEEECCCCCEEE
TEDDACTADGGAAAARVFAAAKVSVVIGFLCTEAIEAAMPILKDANIPVITVGVRTESLT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHH
DRRAKTGWPVYRLGPRGDDERNAVASTLTHLWQKELFAIIDDGTIYGREMAETFRAAAEQ
HHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHEEEEECCEECHHHHHHHHHHHHHH
AALKPVFVDTFRPQLDNQIGMIGRLKKAGATHVFAGGDGDDIAIMGRDAAQLQAGIVFAG
HHCCCEEEECCCHHHCCCCCHHHHHHHCCCCEEEECCCCCEEEEECCCHHHHEECEEEEC
GENLRTPPGDVPYATGTLMIAPPEWADVADAKVLESFSVQKIVPDGYTLPAFAAVEIAKA
CCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHH
ASTLSPGKPLTEVLSGHDFATAIGPVRFDAKGDLSQSPYRVFRFDGARFVPLESN
HHCCCCCCCHHHHHCCCCHHHHCCCEEECCCCCCCCCCEEEEEECCEEEEEECCC
>Mature Secondary Structure
MRPGATISAALAWLFLAGAASAQTLTIGVAAPLSGPSAILGKQIEAGAALAAQADGVELK
CCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHCCHHHCCCEEEECCCCCEEE
TEDDACTADGGAAAARVFAAAKVSVVIGFLCTEAIEAAMPILKDANIPVITVGVRTESLT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHH
DRRAKTGWPVYRLGPRGDDERNAVASTLTHLWQKELFAIIDDGTIYGREMAETFRAAAEQ
HHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHEEEEECCEECHHHHHHHHHHHHHH
AALKPVFVDTFRPQLDNQIGMIGRLKKAGATHVFAGGDGDDIAIMGRDAAQLQAGIVFAG
HHCCCEEEECCCHHHCCCCCHHHHHHHCCCCEEEECCCCCEEEEECCCHHHHEECEEEEC
GENLRTPPGDVPYATGTLMIAPPEWADVADAKVLESFSVQKIVPDGYTLPAFAAVEIAKA
CCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHH
ASTLSPGKPLTEVLSGHDFATAIGPVRFDAKGDLSQSPYRVFRFDGARFVPLESN
HHCCCCCCCHHHHHCCCCHHHHCCCEEECCCCCCCCCCEEEEEECCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]