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The map label for this gene is suhB [H]

Identifier: 13470365

GI number: 13470365

Start: 37989

End: 38816

Strand: Direct

Name: suhB [H]

Synonym: mlr0048

Alternate gene names: 13470365

Gene position: 37989-38816 (Clockwise)

Preceding gene: 13470364

Following gene: 57165210

Centisome position: 0.54

GC content: 65.82

Gene sequence:

>828_bases
ATGACATTTGACGATAACGCGATCGACTGGCTGGCCAGCCTGCTGGCCGAGGCCGCCGACACCGAAATCATGCCCCGCTT
TCGCCGGCTGGGCGACGGCGATATCAGACAGAAGACCTCCGCCGCCGATCTGGTGACGGAAGCGGACGTCAACGCCGAGC
GGCTGATCACCACCAGGCTGCGCCAGAATTATCCCTCGGCCATGGTTGTCGGCGAGGAAGCCTGTTCCGACGATCCGGCG
CTGCTCGACGGGCTGGGCGACGCCGATCTGGCCTTCGTCATCGACCCGGTCGACGGCACCTTCAATTTCGCCTCCGGCGT
GCCGCTGTTCGGCGTCATGCTTGGCGTCGTGGTCAAGGGCGAGACGGTCGCCGGTATCATCCATGATCCGGTCGGCAAGG
ACTGGCTGATCGGCGCCAAGGGTGGCGGCAGTCATATCCGCCATGCGCATGGCAGCCTGGAGAAGGTGCGGGTTGCCGCA
AGCGCGCCGATCTCGCAGATGACCGGCGCGGTCTCCTGGCAGTACATGGCCGAGCCCGACCGCACCCGACTGGCCTGCAA
CCAGACCAAGACGCTGTCGCAGTTCAACTACCGCTGCGCCGCCCACGAATACCGCTTGCTGGCGAGCGGCCATGGCCATT
TCGTCGTCTACAACAAGCTGATGCCGTGGGACCATCTCGCCGGTGTGCTGATCCATGCGGAGGCCGGCGGCCATGCGGCG
CGCTTTGACGGCAGCGCCTATCTGCCGTCGCATGTCGGCGGCGGTCTGCTGGTCGCCCCCGATCGAGAAAGCTGGCAGGA
GTTGCGCCGCGAACTGTGGGCTGGATAG

Upstream 100 bases:

>100_bases
CGCGCGCTGTCCAATACCAGGCCGTCGCATCTGCTCGACAGGAAACTGTTCGATTTCGCCGCCCTGAACCAGACCCTCAT
CACAGGACAAGACGCTTCAG

Downstream 100 bases:

>100_bases
GATCATTTTCCGAGGCCGGCGCTTGACTGCCGGGTTTGTGCGGCCGAAGAATTGGTGCGCAGGCGGGGGCTCTCGAATGA
AATCTCGGTTCGCGATTCTT

Product: monophosphatase-like protein

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTFDDNAIDWLASLLAEAADTEIMPRFRRLGDGDIRQKTSAADLVTEADVNAERLITTRLRQNYPSAMVVGEEACSDDPA
LLDGLGDADLAFVIDPVDGTFNFASGVPLFGVMLGVVVKGETVAGIIHDPVGKDWLIGAKGGGSHIRHAHGSLEKVRVAA
SAPISQMTGAVSWQYMAEPDRTRLACNQTKTLSQFNYRCAAHEYRLLASGHGHFVVYNKLMPWDHLAGVLIHAEAGGHAA
RFDGSAYLPSHVGGGLLVAPDRESWQELRRELWAG

Sequences:

>Translated_275_residues
MTFDDNAIDWLASLLAEAADTEIMPRFRRLGDGDIRQKTSAADLVTEADVNAERLITTRLRQNYPSAMVVGEEACSDDPA
LLDGLGDADLAFVIDPVDGTFNFASGVPLFGVMLGVVVKGETVAGIIHDPVGKDWLIGAKGGGSHIRHAHGSLEKVRVAA
SAPISQMTGAVSWQYMAEPDRTRLACNQTKTLSQFNYRCAAHEYRLLASGHGHFVVYNKLMPWDHLAGVLIHAEAGGHAA
RFDGSAYLPSHVGGGLLVAPDRESWQELRRELWAG
>Mature_274_residues
TFDDNAIDWLASLLAEAADTEIMPRFRRLGDGDIRQKTSAADLVTEADVNAERLITTRLRQNYPSAMVVGEEACSDDPAL
LDGLGDADLAFVIDPVDGTFNFASGVPLFGVMLGVVVKGETVAGIIHDPVGKDWLIGAKGGGSHIRHAHGSLEKVRVAAS
APISQMTGAVSWQYMAEPDRTRLACNQTKTLSQFNYRCAAHEYRLLASGHGHFVVYNKLMPWDHLAGVLIHAEAGGHAAR
FDGSAYLPSHVGGGLLVAPDRESWQELRRELWAG

Specific function: Displays a 20-fold higher rate of hydrolysis of the D isoform of inositol 1-phosphate than of the L isoform [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=213, Percent_Identity=29.1079812206573, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1788882, Length=208, Percent_Identity=29.3269230769231, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193202572, Length=226, Percent_Identity=24.7787610619469, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI193202570, Length=223, Percent_Identity=23.7668161434978, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6321836, Length=252, Percent_Identity=26.5873015873016, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24664922, Length=233, Percent_Identity=29.1845493562232, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21357957, Length=216, Percent_Identity=24.0740740740741, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24664926, Length=218, Percent_Identity=25.6880733944954, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357303, Length=205, Percent_Identity=26.3414634146341, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29703; Mature: 29572

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00629 IMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFDDNAIDWLASLLAEAADTEIMPRFRRLGDGDIRQKTSAADLVTEADVNAERLITTRL
CCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
RQNYPSAMVVGEEACSDDPALLDGLGDADLAFVIDPVDGTFNFASGVPLFGVMLGVVVKG
HHCCCCEEEEEHHHCCCCCHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCC
ETVAGIIHDPVGKDWLIGAKGGGSHIRHAHGSLEKVRVAASAPISQMTGAVSWQYMAEPD
CEEEEEEECCCCCCEEEECCCCCCCHHHHCCCHHHEEEHHCCCHHHHHCCEEEEEECCCC
RTRLACNQTKTLSQFNYRCAAHEYRLLASGHGHFVVYNKLMPWDHLAGVLIHAEAGGHAA
CCEEECCCHHHHHHHCCCHHHHHEEEEECCCCCEEEEECCCCHHHHCEEEEEECCCCCEE
RFDGSAYLPSHVGGGLLVAPDRESWQELRRELWAG
ECCCCCCCHHHCCCCEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TFDDNAIDWLASLLAEAADTEIMPRFRRLGDGDIRQKTSAADLVTEADVNAERLITTRL
CCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
RQNYPSAMVVGEEACSDDPALLDGLGDADLAFVIDPVDGTFNFASGVPLFGVMLGVVVKG
HHCCCCEEEEEHHHCCCCCHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCC
ETVAGIIHDPVGKDWLIGAKGGGSHIRHAHGSLEKVRVAASAPISQMTGAVSWQYMAEPD
CEEEEEEECCCCCCEEEECCCCCCCHHHHCCCHHHEEEHHCCCHHHHHCCEEEEEECCCC
RTRLACNQTKTLSQFNYRCAAHEYRLLASGHGHFVVYNKLMPWDHLAGVLIHAEAGGHAA
CCEEECCCHHHHHHHCCCHHHHHEEEEECCCCCEEEEECCCCHHHHCEEEEEECCCCCEE
RFDGSAYLPSHVGGGLLVAPDRESWQELRRELWAG
ECCCCCCCHHHCCCCEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9720201; 10360571; 10508089 [H]