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The map label for this gene is csd [H]

Identifier: 13470346

GI number: 13470346

Start: 18713

End: 19954

Strand: Direct

Name: csd [H]

Synonym: mlr0021

Alternate gene names: 13470346

Gene position: 18713-19954 (Clockwise)

Preceding gene: 13470345

Following gene: 13470347

Centisome position: 0.27

GC content: 61.11

Gene sequence:

>1242_bases
ATGGACCAGAAAGTCGAAACCACCCCCTACGACGTCGAGGCGATCCGCCGCGACTTCCCGATCCTGTCGCGCGAAGTCTA
TGGCAAGCCGTTGGTCTATCTCGACAATGGGGCGTCGGCGCAGAAGCCGCAGGTGGTGCTGGACACGATCCAGCATGCCT
ATTCCCAGGAATACGCCAACGTCCATCGCGGCCTGCATTTCCTGTCCAACGCAGCGACCGACGCCTATGAAAAGGCGCGC
GAGACGGTGCGCCGTTTCCTCAATGCACCAAGCACCGACAACATCGTCTTCACCTCGAACACGACCTCGGCGATCAACAC
CGTGGCCTATGGCTATGGCATGCCCAATATCGGCGAGGGCGACGAGATCGTGCTGTCGATCATGGAGCACCACTCCAACA
TCGTTCCCTGGCATTTCATCCGCGAGCGGCAGGGCGCCAAACTGGTCTGGGTGCCCGTTGACGATCTCGGCGTCTTCCAC
ATCGAGGAGTTCGAGAAGCGGCTGACCAACCGCACCAAGCTGGTCGCCATCACGCAGATGTCGAATGCGCTGGGCACGGT
GACGCCGATCAAGGAAATCGTGCGCATCGCACATGCGCGCGGCATTCCCGTGCTGGTCGACGGCAGCCAGAGCGCCGTGC
ATATGCCGATCGACGTGCAGGATCTCGACTGCGACTTCTTCGTCTTTACCGGCCACAAGGTGTACGGTCCCTCGGGCATC
GGCGTGCTCTACGGCAAGAAGGATATTCTTGCGGGCATGCGCCCCTTCATGGGCGGCGGCGAGATGATCGAGGAGGTGAC
GGAAGACATCGTCACCTACAATGAGCCGCCGCATCGCTTCGAGGCCGGCACGCCGCCGATCGTCCAGGCGATCGGGCTGG
GTGCCGCTCTCGATTACATGGAAAAGATCGGCCGCGAGCGCATCGCGGCGCACGAGGAAGACCTCAAGACCTACGCGCAT
GAACGGCTGCGCGCGATCAACTCGCTGCGCATCTTCGGCGATGCGCCCGGCAAGGGCGCCATCATTTCCTTTGAACTGCA
AGGCATTCATGCCCATGACGTGTCGATGGTGATAGACAGGCAGGGCGTGGCAGTGCGGGCCGGCACCCATTGTGCCCAGC
CGCTGTTGAAACGCTTTGGTGTAACCTCCACATGCAGGGCATCGTTCGGCATGTATAATACCAGGGCCGAAGTCGACGCT
TTGGCCGAGGCGCTTGAAAAAGCGCGAAAGTTCTTTGGGTGA

Upstream 100 bases:

>100_bases
CGTAGCCGACAAAAAGCCAACGATTTGGCTTTTTGAGCGACGAACGCCCGGAGCCATAGCGAAGGGCCGGCTGACGCGGC
CGGGTATCGAAAGACAGACG

Downstream 100 bases:

>100_bases
TGACGACCATGGACGATGTGAGCGCAACCGCAGAGACCGCGCCGGAAACGGCTGCAAATGGCATCGTATCGGCCTCGGCC
ATTCCCGCTGACGAACTGGC

Product: nifS-like aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MDQKVETTPYDVEAIRRDFPILSREVYGKPLVYLDNGASAQKPQVVLDTIQHAYSQEYANVHRGLHFLSNAATDAYEKAR
ETVRRFLNAPSTDNIVFTSNTTSAINTVAYGYGMPNIGEGDEIVLSIMEHHSNIVPWHFIRERQGAKLVWVPVDDLGVFH
IEEFEKRLTNRTKLVAITQMSNALGTVTPIKEIVRIAHARGIPVLVDGSQSAVHMPIDVQDLDCDFFVFTGHKVYGPSGI
GVLYGKKDILAGMRPFMGGGEMIEEVTEDIVTYNEPPHRFEAGTPPIVQAIGLGAALDYMEKIGRERIAAHEEDLKTYAH
ERLRAINSLRIFGDAPGKGAIISFELQGIHAHDVSMVIDRQGVAVRAGTHCAQPLLKRFGVTSTCRASFGMYNTRAEVDA
LAEALEKARKFFG

Sequences:

>Translated_413_residues
MDQKVETTPYDVEAIRRDFPILSREVYGKPLVYLDNGASAQKPQVVLDTIQHAYSQEYANVHRGLHFLSNAATDAYEKAR
ETVRRFLNAPSTDNIVFTSNTTSAINTVAYGYGMPNIGEGDEIVLSIMEHHSNIVPWHFIRERQGAKLVWVPVDDLGVFH
IEEFEKRLTNRTKLVAITQMSNALGTVTPIKEIVRIAHARGIPVLVDGSQSAVHMPIDVQDLDCDFFVFTGHKVYGPSGI
GVLYGKKDILAGMRPFMGGGEMIEEVTEDIVTYNEPPHRFEAGTPPIVQAIGLGAALDYMEKIGRERIAAHEEDLKTYAH
ERLRAINSLRIFGDAPGKGAIISFELQGIHAHDVSMVIDRQGVAVRAGTHCAQPLLKRFGVTSTCRASFGMYNTRAEVDA
LAEALEKARKFFG
>Mature_413_residues
MDQKVETTPYDVEAIRRDFPILSREVYGKPLVYLDNGASAQKPQVVLDTIQHAYSQEYANVHRGLHFLSNAATDAYEKAR
ETVRRFLNAPSTDNIVFTSNTTSAINTVAYGYGMPNIGEGDEIVLSIMEHHSNIVPWHFIRERQGAKLVWVPVDDLGVFH
IEEFEKRLTNRTKLVAITQMSNALGTVTPIKEIVRIAHARGIPVLVDGSQSAVHMPIDVQDLDCDFFVFTGHKVYGPSGI
GVLYGKKDILAGMRPFMGGGEMIEEVTEDIVTYNEPPHRFEAGTPPIVQAIGLGAALDYMEKIGRERIAAHEEDLKTYAH
ERLRAINSLRIFGDAPGKGAIISFELQGIHAHDVSMVIDRQGVAVRAGTHCAQPLLKRFGVTSTCRASFGMYNTRAEVDA
LAEALEKARKFFG

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=413, Percent_Identity=24.455205811138, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI156713448, Length=425, Percent_Identity=27.0588235294118, Blast_Score=92, Evalue=6e-19,
Organism=Escherichia coli, GI1787970, Length=405, Percent_Identity=46.1728395061728, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1789175, Length=381, Percent_Identity=41.7322834645669, Blast_Score=325, Evalue=3e-90,
Organism=Escherichia coli, GI48994898, Length=394, Percent_Identity=26.6497461928934, Blast_Score=114, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI25143064, Length=229, Percent_Identity=28.82096069869, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI193211090, Length=372, Percent_Identity=25.8064516129032, Blast_Score=102, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6319831, Length=401, Percent_Identity=25.6857855361596, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI20129463, Length=291, Percent_Identity=28.5223367697594, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45750; Mature: 45750

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQKVETTPYDVEAIRRDFPILSREVYGKPLVYLDNGASAQKPQVVLDTIQHAYSQEYAN
CCCCCCCCCCHHHHHHHCCCHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
VHRGLHFLSNAATDAYEKARETVRRFLNAPSTDNIVFTSNTTSAINTVAYGYGMPNIGEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCC
DEIVLSIMEHHSNIVPWHFIRERQGAKLVWVPVDDLGVFHIEEFEKRLTNRTKLVAITQM
HHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEEEH
SNALGTVTPIKEIVRIAHARGIPVLVDGSQSAVHMPIDVQDLDCDFFVFTGHKVYGPSGI
HCHHCCHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCEECCCCEEEEECCEEECCCCC
GVLYGKKDILAGMRPFMGGGEMIEEVTEDIVTYNEPPHRFEAGTPPIVQAIGLGAALDYM
EEEECCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
EKIGRERIAAHEEDLKTYAHERLRAINSLRIFGDAPGKGAIISFELQGIHAHDVSMVIDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEEEECCCEECCEEEEEEC
QGVAVRAGTHCAQPLLKRFGVTSTCRASFGMYNTRAEVDALAEALEKARKFFG
CCCEEECCCHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDQKVETTPYDVEAIRRDFPILSREVYGKPLVYLDNGASAQKPQVVLDTIQHAYSQEYAN
CCCCCCCCCCHHHHHHHCCCHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
VHRGLHFLSNAATDAYEKARETVRRFLNAPSTDNIVFTSNTTSAINTVAYGYGMPNIGEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCC
DEIVLSIMEHHSNIVPWHFIRERQGAKLVWVPVDDLGVFHIEEFEKRLTNRTKLVAITQM
HHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEEEH
SNALGTVTPIKEIVRIAHARGIPVLVDGSQSAVHMPIDVQDLDCDFFVFTGHKVYGPSGI
HCHHCCHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCEECCCCEEEEECCEEECCCCC
GVLYGKKDILAGMRPFMGGGEMIEEVTEDIVTYNEPPHRFEAGTPPIVQAIGLGAALDYM
EEEECCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
EKIGRERIAAHEEDLKTYAHERLRAINSLRIFGDAPGKGAIISFELQGIHAHDVSMVIDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEEEEECCCEECCEEEEEEC
QGVAVRAGTHCAQPLLKRFGVTSTCRASFGMYNTRAEVDALAEALEKARKFFG
CCCEEECCCHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]