Click here to switch to the map view.

The map label for this gene is dtpA [H]

Identifier: 134302329

GI number: 134302329

Start: 1346620

End: 1348113

Strand: Reverse

Name: dtpA [H]

Synonym: FTW_1440

Alternate gene names: 134302329

Gene position: 1348113-1346620 (Counterclockwise)

Preceding gene: 134302330

Following gene: 134302328

Centisome position: 71.01

GC content: 31.06

Gene sequence:

>1494_bases
GTGCAGCATATAGAAGAAAAACAAAGAACAAAATATTTTATTTCATTATTTTTGTTACAATTATTTGAAAGGTTTAGTTT
TTTTGGTTTCTTTTATATCTTAATATTCTTCTGTATAAATAAGCTAAATCTTACAGAGTCGTATGCTTCAACTTTTGCAG
GTTCTTTTACTGCGCTTTGTTATGTTTTAAGCTCATTAGGGGGCTTTATTTCTGATAAGGCTTTAGGTGTTAGAAGAACC
TTAATAGCTGGAGGTATCTGTTTACTATTAGGATATTCATTATTATCAACTAGTGATATGCTAATGAATTTTTCTATTTA
TGTTGGGTTGGCAATGATTATCGTTGGAGCATGTTTATTTGTGCCTATGACTTTAAACAGTGTGTCTAGATTATATGCAG
GAGATCCAGCAAAATTAGACTCTATATATGCTTATTTTAATATGACTAACAATATTGGGGCGTTATCAGGTGCTATTTTG
ATACCTTATTTAAGTAGTGCGGACTCTTACGGCTTAGAAAATAGACACTATGGAATTGCTTTAGGGGTGTGTGCTTGTGG
AGTATTATTAGCTCTTGGTAATATATTTATGAATAAAAAGCTATTTTCGACAATAGCAGCTCCTGTAGGCAAAAAAACAC
TTAGTTTTCAGCAGTTAGTTTTAGCTATAATAGGTATAATATTTTTTGTATCAGTAGTTACTGGATTACTTTATTTTAGT
AGTCTAATTATCATCGTGCTGGTTTTAGCAGTAGTTATGATTGTTGGCTATTTTATAAATATTACTTTTCAGCAAGATAA
AGAGTATCGCTTAAAAATGCTACTTTTATTAGTATTTATATTTTACGCAACAATATTCTTTATGACCTATGCTCAAAAGA
CAACATCATTTTTCTTATTTAATGTTCACCATGTGGATTTGAATGTTTTAGGTATTAAGCTAAATTCGCAAACTGTACCA
GGATTATTAAATACTTCAGGGATTTTAATTTTCTCTCCAATTCTTGCTATGTATTTTAACAAGATGGGTGATAGATTAAG
ATCAACTAGTAAGTTTGCTTTATGTTTATTATTTGCTGGTATATGTTACGCGTTTTTGTACTTTGTTTGTGTATTTAATG
ATCCTTCTTCAAAAGTTTCATTTTGGTGGGAAGTAGTAGCAGTTGGAGTATTTTTCTCATGGGCTGAGATTATGGCAACA
GCTGTTGGTTTATCTTTGATAACCCAACTTGTTCCTACTAAGGTAAGAGGCTTTTGTATGGGGATGTGGTTCTTAACTTG
GGCAGTTGGTATTAAGCTAGGAGCATACGTGGCTTCACTTTATGCTAGTAAAGATTTAGAACACTCAAAGAGCTCTTTGC
TAATTGGGCAAACTAAAATTGATAGTTATCTGGGTTATGAGAATTTATTTATGTGGATTACTATTGTTACTGTAGCTGCT
GCTTTTTCACTTCTAGTCCTAAAAAATAAAATTAATAATGTTATTTATAAATAG

Upstream 100 bases:

>100_bases
GAAAGTAGTACTTTAAAGAGTAATAATTTAACACGATTTGCTGTTTGACTAGTTCAAATAGCTTTAAAACAGCTTGTCGC
TAATATGAGGAGGATGTTAA

Downstream 100 bases:

>100_bases
TATGGGAAATTTATGAATATTCTAAAGATTAGTAAACAAACTTTAAGGAATAATATTAAAATTATTCGAGAGTATATTGG
CAACGCTAAGATGTGTTTTC

Product: amino acid/peptide transporter (peptide:H+ symporter)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MQHIEEKQRTKYFISLFLLQLFERFSFFGFFYILIFFCINKLNLTESYASTFAGSFTALCYVLSSLGGFISDKALGVRRT
LIAGGICLLLGYSLLSTSDMLMNFSIYVGLAMIIVGACLFVPMTLNSVSRLYAGDPAKLDSIYAYFNMTNNIGALSGAIL
IPYLSSADSYGLENRHYGIALGVCACGVLLALGNIFMNKKLFSTIAAPVGKKTLSFQQLVLAIIGIIFFVSVVTGLLYFS
SLIIIVLVLAVVMIVGYFINITFQQDKEYRLKMLLLLVFIFYATIFFMTYAQKTTSFFLFNVHHVDLNVLGIKLNSQTVP
GLLNTSGILIFSPILAMYFNKMGDRLRSTSKFALCLLFAGICYAFLYFVCVFNDPSSKVSFWWEVVAVGVFFSWAEIMAT
AVGLSLITQLVPTKVRGFCMGMWFLTWAVGIKLGAYVASLYASKDLEHSKSSLLIGQTKIDSYLGYENLFMWITIVTVAA
AFSLLVLKNKINNVIYK

Sequences:

>Translated_497_residues
MQHIEEKQRTKYFISLFLLQLFERFSFFGFFYILIFFCINKLNLTESYASTFAGSFTALCYVLSSLGGFISDKALGVRRT
LIAGGICLLLGYSLLSTSDMLMNFSIYVGLAMIIVGACLFVPMTLNSVSRLYAGDPAKLDSIYAYFNMTNNIGALSGAIL
IPYLSSADSYGLENRHYGIALGVCACGVLLALGNIFMNKKLFSTIAAPVGKKTLSFQQLVLAIIGIIFFVSVVTGLLYFS
SLIIIVLVLAVVMIVGYFINITFQQDKEYRLKMLLLLVFIFYATIFFMTYAQKTTSFFLFNVHHVDLNVLGIKLNSQTVP
GLLNTSGILIFSPILAMYFNKMGDRLRSTSKFALCLLFAGICYAFLYFVCVFNDPSSKVSFWWEVVAVGVFFSWAEIMAT
AVGLSLITQLVPTKVRGFCMGMWFLTWAVGIKLGAYVASLYASKDLEHSKSSLLIGQTKIDSYLGYENLFMWITIVTVAA
AFSLLVLKNKINNVIYK
>Mature_497_residues
MQHIEEKQRTKYFISLFLLQLFERFSFFGFFYILIFFCINKLNLTESYASTFAGSFTALCYVLSSLGGFISDKALGVRRT
LIAGGICLLLGYSLLSTSDMLMNFSIYVGLAMIIVGACLFVPMTLNSVSRLYAGDPAKLDSIYAYFNMTNNIGALSGAIL
IPYLSSADSYGLENRHYGIALGVCACGVLLALGNIFMNKKLFSTIAAPVGKKTLSFQQLVLAIIGIIFFVSVVTGLLYFS
SLIIIVLVLAVVMIVGYFINITFQQDKEYRLKMLLLLVFIFYATIFFMTYAQKTTSFFLFNVHHVDLNVLGIKLNSQTVP
GLLNTSGILIFSPILAMYFNKMGDRLRSTSKFALCLLFAGICYAFLYFVCVFNDPSSKVSFWWEVVAVGVFFSWAEIMAT
AVGLSLITQLVPTKVRGFCMGMWFLTWAVGIKLGAYVASLYASKDLEHSKSSLLIGQTKIDSYLGYENLFMWITIVTVAA
AFSLLVLKNKINNVIYK

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787922, Length=438, Percent_Identity=30.8219178082192, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1789911, Length=495, Percent_Identity=28.8888888888889, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI1786927, Length=438, Percent_Identity=24.8858447488584, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790572, Length=468, Percent_Identity=23.9316239316239, Blast_Score=86, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 55338; Mature: 55338

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]