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The map label for this gene is spoU [H]

Identifier: 134302313

GI number: 134302313

Start: 1326885

End: 1327637

Strand: Direct

Name: spoU [H]

Synonym: FTW_1418

Alternate gene names: 134302313

Gene position: 1326885-1327637 (Clockwise)

Preceding gene: 134302312

Following gene: 134302314

Centisome position: 69.89

GC content: 34.93

Gene sequence:

>753_bases
ATGAAAAATCTTAGCCAAAAACTCTATAAAGAAATAAAAAAACTGCATAGTTCTCAAGGTCGAAAAAAGTCACAGTACTA
CGTCATTGAAGGACTTAGATGCTCTCAAGAAGCACTCAAAAGATTACCACAACAACAAATAATCGCGATCTTGGTAACTG
AGAAAGCAGATAATCCAAACTACCCGCTAAATAAAAAGTATATTATTACTGAGAAAGATTTCGAAGCACTATCACAAACA
CAAAATCCACAAGGAGTTTTAATCTTAGCTGAAAAACCTAAGCTTGAACAACTTAGCTTTGATGATGACTTTATCCTAGT
ATTTGATAGAATCCAAGATCCTGGTAATATTGGCACAATTCTACGTACGGCTATAGCTGTAGGATTAAAAGAAGTAATCT
TAATCAATGGTACTGTTGATCCATTTAACCCCAAAGCGATAAGGGCTGGTATGGGCGCACAGTTTAGTCTCAAATTTGGC
TATATTACAAATCTTGCCAAGCTAAAAAATATCGCTAAATTACAGCAGCGCAAAATATGGTTAACTACACCACATCAAGG
GGTATCATGCTATGCTAAAGAGTTTAAACTTGCTAATAGTATTTTAGTTTTTGGTGAAGAAGCTAATGGTATCGAAGATT
TTTCTGTAGGTCAAAAAACTATGATACCTACACTTAGTGATATAGAGTCGCTAAATGTAGCTCAAGCTGCAACGATATAT
TTATTTGAGGGTTTACGCCAACGACTTCGATAA

Upstream 100 bases:

>100_bases
ACATTTCTGACAAACTATAGCAAAAATACACAGTAAAGCTATTTAAACACCTCGCCAAAAAACATACAATAACTAACAAA
ATTCTTAGCTAATTAATTTA

Downstream 100 bases:

>100_bases
GATAACTTTTTAAAAAAATCAAAACATGGCTATATAAATTACTCTATCTATATGTATAATAATCAATAATTATCATTTAA
AAAAATATTTAAAATGCTTA

Product: rRNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MKNLSQKLYKEIKKLHSSQGRKKSQYYVIEGLRCSQEALKRLPQQQIIAILVTEKADNPNYPLNKKYIITEKDFEALSQT
QNPQGVLILAEKPKLEQLSFDDDFILVFDRIQDPGNIGTILRTAIAVGLKEVILINGTVDPFNPKAIRAGMGAQFSLKFG
YITNLAKLKNIAKLQQRKIWLTTPHQGVSCYAKEFKLANSILVFGEEANGIEDFSVGQKTMIPTLSDIESLNVAQAATIY
LFEGLRQRLR

Sequences:

>Translated_250_residues
MKNLSQKLYKEIKKLHSSQGRKKSQYYVIEGLRCSQEALKRLPQQQIIAILVTEKADNPNYPLNKKYIITEKDFEALSQT
QNPQGVLILAEKPKLEQLSFDDDFILVFDRIQDPGNIGTILRTAIAVGLKEVILINGTVDPFNPKAIRAGMGAQFSLKFG
YITNLAKLKNIAKLQQRKIWLTTPHQGVSCYAKEFKLANSILVFGEEANGIEDFSVGQKTMIPTLSDIESLNVAQAATIY
LFEGLRQRLR
>Mature_250_residues
MKNLSQKLYKEIKKLHSSQGRKKSQYYVIEGLRCSQEALKRLPQQQIIAILVTEKADNPNYPLNKKYIITEKDFEALSQT
QNPQGVLILAEKPKLEQLSFDDDFILVFDRIQDPGNIGTILRTAIAVGLKEVILINGTVDPFNPKAIRAGMGAQFSLKFG
YITNLAKLKNIAKLQQRKIWLTTPHQGVSCYAKEFKLANSILVFGEEANGIEDFSVGQKTMIPTLSDIESLNVAQAATIY
LFEGLRQRLR

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI8922534, Length=237, Percent_Identity=28.6919831223629, Blast_Score=96, Evalue=3e-20,
Organism=Escherichia coli, GI1790623, Length=154, Percent_Identity=31.8181818181818, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24666840, Length=280, Percent_Identity=26.7857142857143, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 28186; Mature: 28186

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLSQKLYKEIKKLHSSQGRKKSQYYVIEGLRCSQEALKRLPQQQIIAILVTEKADNPN
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHCCHHHEEEEEEEECCCCCC
YPLNKKYIITEKDFEALSQTQNPQGVLILAEKPKLEQLSFDDDFILVFDRIQDPGNIGTI
CCCCCEEEEECHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCHHHH
LRTAIAVGLKEVILINGTVDPFNPKAIRAGMGAQFSLKFGYITNLAKLKNIAKLQQRKIW
HHHHHHHCCCEEEEEECCCCCCCCHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHCEEE
LTTPHQGVSCYAKEFKLANSILVFGEEANGIEDFSVGQKTMIPTLSDIESLNVAQAATIY
EECCCCCHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCHHCCCCHHHHHHCCHHHHHHHH
LFEGLRQRLR
HHHHHHHHCC
>Mature Secondary Structure
MKNLSQKLYKEIKKLHSSQGRKKSQYYVIEGLRCSQEALKRLPQQQIIAILVTEKADNPN
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHCCHHHEEEEEEEECCCCCC
YPLNKKYIITEKDFEALSQTQNPQGVLILAEKPKLEQLSFDDDFILVFDRIQDPGNIGTI
CCCCCEEEEECHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCHHHH
LRTAIAVGLKEVILINGTVDPFNPKAIRAGMGAQFSLKFGYITNLAKLKNIAKLQQRKIW
HHHHHHHCCCEEEEEECCCCCCCCHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHCEEE
LTTPHQGVSCYAKEFKLANSILVFGEEANGIEDFSVGQKTMIPTLSDIESLNVAQAATIY
EECCCCCHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCHHCCCCHHHHHHCCHHHHHHHH
LFEGLRQRLR
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]