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The map label for this gene is yafC [H]

Identifier: 134302182

GI number: 134302182

Start: 1180241

End: 1181140

Strand: Direct

Name: yafC [H]

Synonym: FTW_1249

Alternate gene names: 134302182

Gene position: 1180241-1181140 (Clockwise)

Preceding gene: 134302173

Following gene: 134302185

Centisome position: 62.17

GC content: 32.89

Gene sequence:

>900_bases
ATGAACAATATTCATTGGCGAGGTATTTATTGTTTCATCCATGTTGCCGAACAACAAAGCTTTACTAAGGCAGCAGATAT
ACTAGGTATGGCTAAGTCAAATCTGAGCCAAAATATTAAAGACCTAGAAAACCATCTTAAAGTTCAACTACTATATAGAA
GCACTAGACATGTCAGATTAACAGAAATAGGAAAAGAGTATTATCAAAAATGCAAAAAAGCTCTCCAAGATTTAGATATA
GCTACTGAACTTGCTAGCCAAGAAAGTAATCAGCTTAGTGGAATTATAAAAATAAATAGCGTTGGTGGCATACTTGGTGA
AGAAGTAATAGCTCCAATATTGCTCAACTTCCAGCAACAGAATCCTAAAGTTAATATCCATTTAGATTTCTCTAGTCACA
AGGTCAATCTTTTGGATAGTGATTACGACTTAGTAATACGTATGGGCAATCTTGTAGATTCTAACCTTATAGTTTCGCCT
TTACGTACTGTTGCTACCAAATATGTTGCTAGTCATGATTTTATTCAAAAGCATGGGCAAGTAACCAATCCTCGTCAGCT
CGAAAACTTACCACTAATTTATGGTAATGTCAAACGGTGGTCATTAATCTCAAATAAAGATAAATATACTCTACATATTC
ATAATAATGGCATTCATGTCACCAGTGGTAGAGTTATGAAGCAGGCTGCATTAGCAGGATTAGGGATTACTCGACTTGTA
GATATTTATGTAGAGTCTGATATCAAAAATGGAAATTTAGTCGAAGTCTTGTCAGATTATACTGAAACCACTCCATTATC
TATTATTTCGCTGCCAGTCAAATATCAACTTAAAAGAATAAATTCATTAATAAAATATCTAAAACAACATTTTAACGAAT
TATATTTAGAAATGCTTTAA

Upstream 100 bases:

>100_bases
TTTTTTGTTTTGATTTTTACATAACTTCATTGGTTGTAAATTCTATACAAACTTATTAAACTGATAAATACCAACAATCA
TAAAATATTGTTATCAAATA

Downstream 100 bases:

>100_bases
TATAAAATAATTACTTACTGTAGTAATATTGATAAAGAATCTTATCATAACGAATTGTTATTTTTTTAAAATTTCTTCTG
ACTTGCTGTTTGGTATGATC

Product: transcriptional regulator, LysR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MNNIHWRGIYCFIHVAEQQSFTKAADILGMAKSNLSQNIKDLENHLKVQLLYRSTRHVRLTEIGKEYYQKCKKALQDLDI
ATELASQESNQLSGIIKINSVGGILGEEVIAPILLNFQQQNPKVNIHLDFSSHKVNLLDSDYDLVIRMGNLVDSNLIVSP
LRTVATKYVASHDFIQKHGQVTNPRQLENLPLIYGNVKRWSLISNKDKYTLHIHNNGIHVTSGRVMKQAALAGLGITRLV
DIYVESDIKNGNLVEVLSDYTETTPLSIISLPVKYQLKRINSLIKYLKQHFNELYLEML

Sequences:

>Translated_299_residues
MNNIHWRGIYCFIHVAEQQSFTKAADILGMAKSNLSQNIKDLENHLKVQLLYRSTRHVRLTEIGKEYYQKCKKALQDLDI
ATELASQESNQLSGIIKINSVGGILGEEVIAPILLNFQQQNPKVNIHLDFSSHKVNLLDSDYDLVIRMGNLVDSNLIVSP
LRTVATKYVASHDFIQKHGQVTNPRQLENLPLIYGNVKRWSLISNKDKYTLHIHNNGIHVTSGRVMKQAALAGLGITRLV
DIYVESDIKNGNLVEVLSDYTETTPLSIISLPVKYQLKRINSLIKYLKQHFNELYLEML
>Mature_299_residues
MNNIHWRGIYCFIHVAEQQSFTKAADILGMAKSNLSQNIKDLENHLKVQLLYRSTRHVRLTEIGKEYYQKCKKALQDLDI
ATELASQESNQLSGIIKINSVGGILGEEVIAPILLNFQQQNPKVNIHLDFSSHKVNLLDSDYDLVIRMGNLVDSNLIVSP
LRTVATKYVASHDFIQKHGQVTNPRQLENLPLIYGNVKRWSLISNKDKYTLHIHNNGIHVTSGRVMKQAALAGLGITRLV
DIYVESDIKNGNLVEVLSDYTETTPLSIISLPVKYQLKRINSLIKYLKQHFNELYLEML

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=287, Percent_Identity=31.3588850174216, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI145693193, Length=318, Percent_Identity=30.5031446540881, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI87081978, Length=292, Percent_Identity=28.4246575342466, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787589, Length=267, Percent_Identity=28.4644194756554, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789639, Length=297, Percent_Identity=27.9461279461279, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787128, Length=285, Percent_Identity=25.6140350877193, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789440, Length=281, Percent_Identity=23.4875444839858, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787601, Length=120, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI157672245, Length=183, Percent_Identity=31.1475409836066, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788706, Length=291, Percent_Identity=25.7731958762887, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786448, Length=255, Percent_Identity=24.7058823529412, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34016; Mature: 34016

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIHWRGIYCFIHVAEQQSFTKAADILGMAKSNLSQNIKDLENHLKVQLLYRSTRHVRL
CCCCEEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEH
TEIGKEYYQKCKKALQDLDIATELASQESNQLSGIIKINSVGGILGEEVIAPILLNFQQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCC
NPKVNIHLDFSSHKVNLLDSDYDLVIRMGNLVDSNLIVSPLRTVATKYVASHDFIQKHGQ
CCEEEEEEEECCCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
VTNPRQLENLPLIYGNVKRWSLISNKDKYTLHIHNNGIHVTSGRVMKQAALAGLGITRLV
CCCCHHHCCCCEEEECCEEEEEECCCCEEEEEEECCCEEEECCHHHHHHHHHCCCHHHHH
DIYVESDIKNGNLVEVLSDYTETTPLSIISLPVKYQLKRINSLIKYLKQHFNELYLEML
HHHEECCCCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNNIHWRGIYCFIHVAEQQSFTKAADILGMAKSNLSQNIKDLENHLKVQLLYRSTRHVRL
CCCCEEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEH
TEIGKEYYQKCKKALQDLDIATELASQESNQLSGIIKINSVGGILGEEVIAPILLNFQQQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCC
NPKVNIHLDFSSHKVNLLDSDYDLVIRMGNLVDSNLIVSPLRTVATKYVASHDFIQKHGQ
CCEEEEEEEECCCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
VTNPRQLENLPLIYGNVKRWSLISNKDKYTLHIHNNGIHVTSGRVMKQAALAGLGITRLV
CCCCHHHCCCCEEEECCEEEEEECCCCEEEEEEECCCEEEECCHHHHHHHHHCCCHHHHH
DIYVESDIKNGNLVEVLSDYTETTPLSIISLPVKYQLKRINSLIKYLKQHFNELYLEML
HHHEECCCCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]