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The map label for this gene is sbcB [H]

Identifier: 134302180

GI number: 134302180

Start: 1177821

End: 1179269

Strand: Reverse

Name: sbcB [H]

Synonym: FTW_1247

Alternate gene names: 134302180

Gene position: 1179269-1177821 (Counterclockwise)

Preceding gene: 134302181

Following gene: 134302179

Centisome position: 62.12

GC content: 33.06

Gene sequence:

>1449_bases
ATGTTTAGTAATCAGACTTTATTATTTTATGATTTAGAGACTAGTGGTATAAATAATTCTTTTGATCAAGTATTGCAATT
TGCTGCAATTAGGACCGACTTGGATTTCAATGAGATTGAGAGATTTAATTTTTTTGTAAAATTAAATCCTGACACCACGC
CATCACCTATGGCAACAATTACGCATCATATTTCTATTGCTCAAGCAAATACTGGTATAGCAGAATATCAAGCGATTCGA
AAAATTCATAAAATTATCAATGCTCCAGGAACTATAAGTATAGGTTATAATACTCTTGGATTTGATGATGAGTTTTTGAG
ATTCGCTTTTTACAAAAATATGTTACCTCCATATAGTCATCAGTTTAAAAATGGTTGCTCAAGAGCTGATTTGTTTCCAA
TAGTTACATGTTATTACTTATTCTGTAATGAAGTATTAAACTGGCCTAAGGCTATCGACGAGGGTGGACAAGAGAAAACT
TCTCTAAAACTTGAAAATTTAAATCAAAATAACAATCTCTATAGTGGCGGTAGAGCTCATGATGCTATTACAGATGTGAT
TGTTACTGTAGAATTAGCTAAAAAGCTAAGAGCCGCAAATCCAAAGATGTGGCAGTTTTTGCTAGCAAAATTTAATAAGC
AAAATGATGAAAATACCTTAACACAACTTGATGTTGGGCTAGAGGTTGGGGATCGTAAATATAAACAAGCAATAGCTGTA
AGTGGTATATTTGGCTCGAAGAATAATTTTATCTCGGCAATATTGGATTTAGGACAACATCGACACTATAAAAACCAAGA
GATATTTCTACGCTTAGATAGTTGTCTATTTAGTGATTTTATAGATGAGTTCGGCAGTCTTGAAGCTGAGCATTGGCGTC
TAACTTTAAATAAAAAATGGGGCGATATCCCTATTATCCTACCAGCTAAGACTCGTTTTGTCGGTAAGCTGCCACAAGAA
AGAATCGAGCTTATCAAAGCTAATAAAGAATTTATAAGAAATAATCCAGAGACTTTTGCTAACTTTGTTGAGTATGTTTT
AGAATATAAATATCCCGAGATAGAAAATATTGACACTGATGCGGCAATTTATCAAAGTGACTTTATGAGTATGGCTGATG
AGAGAGGTTGTGATAAATTTCATAGCTTGGCTATTACGCAAAAGGCACAAATGCTTAATCAGTTACCAAAATCTTATTAT
GACAGGGCTGTGCGTATAATTGGTAGATTAGACTTTTCAAAATTACCAGCAAAAGCTCAGATCGAGTTTCAAGATTATTT
AAATAAAATTGTTAGCCTAGATAGTGATGAGTTGTTGATTGATCACAAAGGCAAAACTCGTAAAACTCTGGAAGATATTT
ATCAGGAAATAGAAGATTTACGTATGAATTACGATCTAACAGAAGAGCAACAAGCTTTGTTGTATGAGTTAGAGGAGTAT
TTGTTTTAA

Upstream 100 bases:

>100_bases
TGAAAAATAAAGTTTGAAAGTAGTCTAAATTACTAATCACCTTAAAGGTATGTTAAAATTCTAAATTAGTAATTTTATGA
AATAAAAAAATGTATTTTAG

Downstream 100 bases:

>100_bases
GATGAATAAATTCAACCTAGTAACAAAGTATGCTCCAGCTGGCGATCAGCCTCAAGCAATACAAAGCCTTGTTAATGGTA
TAAATACTGGGTTACAACAC

Product: exonuclease

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MFSNQTLLFYDLETSGINNSFDQVLQFAAIRTDLDFNEIERFNFFVKLNPDTTPSPMATITHHISIAQANTGIAEYQAIR
KIHKIINAPGTISIGYNTLGFDDEFLRFAFYKNMLPPYSHQFKNGCSRADLFPIVTCYYLFCNEVLNWPKAIDEGGQEKT
SLKLENLNQNNNLYSGGRAHDAITDVIVTVELAKKLRAANPKMWQFLLAKFNKQNDENTLTQLDVGLEVGDRKYKQAIAV
SGIFGSKNNFISAILDLGQHRHYKNQEIFLRLDSCLFSDFIDEFGSLEAEHWRLTLNKKWGDIPIILPAKTRFVGKLPQE
RIELIKANKEFIRNNPETFANFVEYVLEYKYPEIENIDTDAAIYQSDFMSMADERGCDKFHSLAITQKAQMLNQLPKSYY
DRAVRIIGRLDFSKLPAKAQIEFQDYLNKIVSLDSDELLIDHKGKTRKTLEDIYQEIEDLRMNYDLTEEQQALLYELEEY
LF

Sequences:

>Translated_482_residues
MFSNQTLLFYDLETSGINNSFDQVLQFAAIRTDLDFNEIERFNFFVKLNPDTTPSPMATITHHISIAQANTGIAEYQAIR
KIHKIINAPGTISIGYNTLGFDDEFLRFAFYKNMLPPYSHQFKNGCSRADLFPIVTCYYLFCNEVLNWPKAIDEGGQEKT
SLKLENLNQNNNLYSGGRAHDAITDVIVTVELAKKLRAANPKMWQFLLAKFNKQNDENTLTQLDVGLEVGDRKYKQAIAV
SGIFGSKNNFISAILDLGQHRHYKNQEIFLRLDSCLFSDFIDEFGSLEAEHWRLTLNKKWGDIPIILPAKTRFVGKLPQE
RIELIKANKEFIRNNPETFANFVEYVLEYKYPEIENIDTDAAIYQSDFMSMADERGCDKFHSLAITQKAQMLNQLPKSYY
DRAVRIIGRLDFSKLPAKAQIEFQDYLNKIVSLDSDELLIDHKGKTRKTLEDIYQEIEDLRMNYDLTEEQQALLYELEEY
LF
>Mature_482_residues
MFSNQTLLFYDLETSGINNSFDQVLQFAAIRTDLDFNEIERFNFFVKLNPDTTPSPMATITHHISIAQANTGIAEYQAIR
KIHKIINAPGTISIGYNTLGFDDEFLRFAFYKNMLPPYSHQFKNGCSRADLFPIVTCYYLFCNEVLNWPKAIDEGGQEKT
SLKLENLNQNNNLYSGGRAHDAITDVIVTVELAKKLRAANPKMWQFLLAKFNKQNDENTLTQLDVGLEVGDRKYKQAIAV
SGIFGSKNNFISAILDLGQHRHYKNQEIFLRLDSCLFSDFIDEFGSLEAEHWRLTLNKKWGDIPIILPAKTRFVGKLPQE
RIELIKANKEFIRNNPETFANFVEYVLEYKYPEIENIDTDAAIYQSDFMSMADERGCDKFHSLAITQKAQMLNQLPKSYY
DRAVRIIGRLDFSKLPAKAQIEFQDYLNKIVSLDSDELLIDHKGKTRKTLEDIYQEIEDLRMNYDLTEEQQALLYELEEY
LF

Specific function: Also functions as a DNA deoxyribophosphodiesterase that release deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=269, Percent_Identity=33.457249070632, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 55773; Mature: 55773

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSNQTLLFYDLETSGINNSFDQVLQFAAIRTDLDFNEIERFNFFVKLNPDTTPSPMATI
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHEEEEEEECCCCCCCCHHHH
THHISIAQANTGIAEYQAIRKIHKIINAPGTISIGYNTLGFDDEFLRFAFYKNMLPPYSH
HHHEEEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCHH
QFKNGCSRADLFPIVTCYYLFCNEVLNWPKAIDEGGQEKTSLKLENLNQNNNLYSGGRAH
HHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHEEEEECCCCCCCCCCCCCHH
DAITDVIVTVELAKKLRAANPKMWQFLLAKFNKQNDENTLTQLDVGLEVGDRKYKQAIAV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHEECCCCCCCHHHHHHHHH
SGIFGSKNNFISAILDLGQHRHYKNQEIFLRLDSCLFSDFIDEFGSLEAEHWRLTLNKKW
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEEEEECCC
GDIPIILPAKTRFVGKLPQERIELIKANKEFIRNNPETFANFVEYVLEYKYPEIENIDTD
CCCCEEECCCHHHHHCCCHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCH
AAIYQSDFMSMADERGCDKFHSLAITQKAQMLNQLPKSYYDRAVRIIGRLDFSKLPAKAQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEE
IEFQDYLNKIVSLDSDELLIDHKGKTRKTLEDIYQEIEDLRMNYDLTEEQQALLYELEEY
EEHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LF
CC
>Mature Secondary Structure
MFSNQTLLFYDLETSGINNSFDQVLQFAAIRTDLDFNEIERFNFFVKLNPDTTPSPMATI
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHEEEEEEECCCCCCCCHHHH
THHISIAQANTGIAEYQAIRKIHKIINAPGTISIGYNTLGFDDEFLRFAFYKNMLPPYSH
HHHEEEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCHH
QFKNGCSRADLFPIVTCYYLFCNEVLNWPKAIDEGGQEKTSLKLENLNQNNNLYSGGRAH
HHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHEEEEECCCCCCCCCCCCCHH
DAITDVIVTVELAKKLRAANPKMWQFLLAKFNKQNDENTLTQLDVGLEVGDRKYKQAIAV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHEECCCCCCCHHHHHHHHH
SGIFGSKNNFISAILDLGQHRHYKNQEIFLRLDSCLFSDFIDEFGSLEAEHWRLTLNKKW
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEEEEECCC
GDIPIILPAKTRFVGKLPQERIELIKANKEFIRNNPETFANFVEYVLEYKYPEIENIDTD
CCCCEEECCCHHHHHCCCHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCH
AAIYQSDFMSMADERGCDKFHSLAITQKAQMLNQLPKSYYDRAVRIIGRLDFSKLPAKAQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEE
IEFQDYLNKIVSLDSDELLIDHKGKTRKTLEDIYQEIEDLRMNYDLTEEQQALLYELEEY
EEHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LF
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]