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The map label for this gene is corC [H]

Identifier: 134302077

GI number: 134302077

Start: 1054455

End: 1055297

Strand: Direct

Name: corC [H]

Synonym: FTW_1113

Alternate gene names: 134302077

Gene position: 1054455-1055297 (Clockwise)

Preceding gene: 134302076

Following gene: 134302078

Centisome position: 55.54

GC content: 30.49

Gene sequence:

>843_bases
ATGGCAGATAATAATCCTTTTATAAAAAGACTTACCTCAAGCATTTTTAATATAAAAAGTGAAGAAGCTCTTATCGATGC
TATCAATAGAGCTGCTGCTAATGAGGTTATTGATAAGACATCACAAAATATGCTAATAGGTGCGATGAAAATATCGTCAT
TAGATGTTGGTGATATTATGATATCGCATACAAAAATAGTTGCTGTAGATATGTCTATGTCTATTAGAGAGATCTTAAAA
AAGACGATAAACTCTAGTCATACGCGACTACCAGTCTACTGTGAAAACAAATCTGAAATACTAGGAATTTTACACTCAAA
AGACCTACTAAAACTAATCTTTGAAAAAGAAATTGAATCTGCTGATGATGAAGAACTCAAAGCAGAAGATATTAAAAATA
TTCTGCGCCCTGCTATCTTTATCCCTGAGACAAAAAAACTCAATGCTATGCTCAAAGATTTCAAAAATAGTCAAAATCAT
ATTGCTATAGTAGTTGATGAATATGGAGCTATTTCTGGATTAATAACTATTGAGGATGTTTTAGAAGAAATAGTCGGTGA
TATTGAGGATGAGTTTGATATCACTAGCCAAAATATAGTTAAAATGGCAGATGATAAGTTTATATTAGATGCTACAACTA
CTATAGAAGACTTCAATGAATATTTTGCCACATCAATAGATGACAATAGTGATTATGACACTATTGCTGGGATGATTATT
CAAACTTTAGAGTGTTTACCTCAAAAAGGTGATAGCATTGTCGTTGATGGCTTGAAATTTACAGTTCAAGAAGCAGATAA
TAGAAAAATTATTAAAATTTTAGTCGAAAAATTTAAGAAATAA

Upstream 100 bases:

>100_bases
CACCAAGATGATCAAGAAGCTGAAGTGATGGAGAATTTAGAAATACAACTACTAGCACAGCTAGGAATAGCTAATCCATA
TATTGAACAAGAGAATCAAA

Downstream 100 bases:

>100_bases
TGAAGAAGTTAATATTTAGAATAGTTCTGCCACTATTAAGTGGTGCAATACTTACTTTAGCATTTGCACCTTTCCGTATA
GATATACTAGCTTTAATATC

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MADNNPFIKRLTSSIFNIKSEEALIDAINRAAANEVIDKTSQNMLIGAMKISSLDVGDIMISHTKIVAVDMSMSIREILK
KTINSSHTRLPVYCENKSEILGILHSKDLLKLIFEKEIESADDEELKAEDIKNILRPAIFIPETKKLNAMLKDFKNSQNH
IAIVVDEYGAISGLITIEDVLEEIVGDIEDEFDITSQNIVKMADDKFILDATTTIEDFNEYFATSIDDNSDYDTIAGMII
QTLECLPQKGDSIVVDGLKFTVQEADNRKIIKILVEKFKK

Sequences:

>Translated_280_residues
MADNNPFIKRLTSSIFNIKSEEALIDAINRAAANEVIDKTSQNMLIGAMKISSLDVGDIMISHTKIVAVDMSMSIREILK
KTINSSHTRLPVYCENKSEILGILHSKDLLKLIFEKEIESADDEELKAEDIKNILRPAIFIPETKKLNAMLKDFKNSQNH
IAIVVDEYGAISGLITIEDVLEEIVGDIEDEFDITSQNIVKMADDKFILDATTTIEDFNEYFATSIDDNSDYDTIAGMII
QTLECLPQKGDSIVVDGLKFTVQEADNRKIIKILVEKFKK
>Mature_279_residues
ADNNPFIKRLTSSIFNIKSEEALIDAINRAAANEVIDKTSQNMLIGAMKISSLDVGDIMISHTKIVAVDMSMSIREILKK
TINSSHTRLPVYCENKSEILGILHSKDLLKLIFEKEIESADDEELKAEDIKNILRPAIFIPETKKLNAMLKDFKNSQNHI
AIVVDEYGAISGLITIEDVLEEIVGDIEDEFDITSQNIVKMADDKFILDATTTIEDFNEYFATSIDDNSDYDTIAGMIIQ
TLECLPQKGDSIVVDGLKFTVQEADNRKIIKILVEKFKK

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=214, Percent_Identity=29.9065420560748, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI94681046, Length=203, Percent_Identity=29.064039408867, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1786879, Length=273, Percent_Identity=38.0952380952381, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI145693175, Length=218, Percent_Identity=28.8990825688073, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI87082033, Length=291, Percent_Identity=25.4295532646048, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1790664, Length=253, Percent_Identity=24.5059288537549, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788119, Length=230, Percent_Identity=26.9565217391304, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 31420; Mature: 31289

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADNNPFIKRLTSSIFNIKSEEALIDAINRAAANEVIDKTSQNMLIGAMKISSLDVGDIM
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHEE
ISHTKIVAVDMSMSIREILKKTINSSHTRLPVYCENKSEILGILHSKDLLKLIFEKEIES
EECEEEEEEECCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCC
ADDEELKAEDIKNILRPAIFIPETKKLNAMLKDFKNSQNHIAIVVDEYGAISGLITIEDV
CCCHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHEEHHHH
LEEIVGDIEDEFDITSQNIVKMADDKFILDATTTIEDFNEYFATSIDDNSDYDTIAGMII
HHHHHHCCHHHCCCCHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
QTLECLPQKGDSIVVDGLKFTVQEADNRKIIKILVEKFKK
HHHHHHCCCCCEEEEECEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ADNNPFIKRLTSSIFNIKSEEALIDAINRAAANEVIDKTSQNMLIGAMKISSLDVGDIM
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHEE
ISHTKIVAVDMSMSIREILKKTINSSHTRLPVYCENKSEILGILHSKDLLKLIFEKEIES
EECEEEEEEECCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCC
ADDEELKAEDIKNILRPAIFIPETKKLNAMLKDFKNSQNHIAIVVDEYGAISGLITIEDV
CCCHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHEEHHHH
LEEIVGDIEDEFDITSQNIVKMADDKFILDATTTIEDFNEYFATSIDDNSDYDTIAGMII
HHHHHHCCHHHCCCCHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
QTLECLPQKGDSIVVDGLKFTVQEADNRKIIKILVEKFKK
HHHHHHCCCCCEEEEECEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]