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The map label for this gene is prmA [H]

Identifier: 134302002

GI number: 134302002

Start: 972000

End: 972845

Strand: Reverse

Name: prmA [H]

Synonym: FTW_1026

Alternate gene names: 134302002

Gene position: 972845-972000 (Counterclockwise)

Preceding gene: 134302003

Following gene: 134302001

Centisome position: 51.24

GC content: 31.68

Gene sequence:

>846_bases
ATGCAACAATGGCACCAATTAGAGTTTAGACTAAAATCCAAATATTTTGATAGAATAGAGAATTATCTTTTTGATAATGA
TGCAGGTTCTGTAACAAGGATAGATAAGTCTGATGATATCGTTAGTATTACTGTTTTATATGAGAATCATCATGATATAG
ATACTATTATAGCTAATATTAAACAAAAGTTTGAAAACATAATAGAAAGTGAAATAAGTTATGAGATTATCAAAGATCAG
CAGTGGGAAGCAGCTTGGTTATATGATTATGAACCTATAGAGATTGGTAATAATATAGTCGTTTATCCAAATTGGCGTCA
GCCTCCACAAGATAATAAGCATACATATATAATAGTTGATCCAAGTATTGCTTTTGGTTGTGGTAATCATGAGACGACTA
AGATGTGTCTTGAATGGTTAGAGCAGCATGTTAGCAAAGATACGACAGTCCTAGACTATGGTTGTGGTACTGGCGTGCTA
GCAATTGGAGCTGTTAAGTTAGGTGCGAAATATGCTGAAGGTATAGATATTGATCCTAACTCAATAGAGTCATCTATTAA
AAATGCTCAAGAAAATGATGTAACTGATAAAACTCATTTTAGCGATAATCCTCCAACACAGCAGTTTGATCTAGTAGTAG
CAAATATTTTTTCAAATGTTTTGATAAGTTTGGTTGGAAATATCACAACTAGTTTAAAAAAAGGTGGTAGATTAGCTTTA
TCTGGAATTATTGAAAATCAAGTTGATGAAGTTCAACAAGAGTTTAAAAAATACGCTATAACTTTTAATCAACCAAAGCA
GATGGGGCAATGGTTTTTATTAGATGGGATAAAAAATGGACTTTAA

Upstream 100 bases:

>100_bases
TGCTTTAGAAAATTTCACATAATTTTATTTCGAACTCAGTTTATATCTAGTATTATTTAACTTTATATAAGTTTTATATA
AGTTTTTAAGTTTTTATAAG

Downstream 100 bases:

>100_bases
AATTGCAGATATAGAAATCGAAAATAATGTTGTACTTGCACCAATGGCGGGTTTCTGTGATAGTGCATTTCGTACTATAT
GCAAAGAGCATGGGGCTGGT

Product: 50S ribosomal protein L11, methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MQQWHQLEFRLKSKYFDRIENYLFDNDAGSVTRIDKSDDIVSITVLYENHHDIDTIIANIKQKFENIIESEISYEIIKDQ
QWEAAWLYDYEPIEIGNNIVVYPNWRQPPQDNKHTYIIVDPSIAFGCGNHETTKMCLEWLEQHVSKDTTVLDYGCGTGVL
AIGAVKLGAKYAEGIDIDPNSIESSIKNAQENDVTDKTHFSDNPPTQQFDLVVANIFSNVLISLVGNITTSLKKGGRLAL
SGIIENQVDEVQQEFKKYAITFNQPKQMGQWFLLDGIKNGL

Sequences:

>Translated_281_residues
MQQWHQLEFRLKSKYFDRIENYLFDNDAGSVTRIDKSDDIVSITVLYENHHDIDTIIANIKQKFENIIESEISYEIIKDQ
QWEAAWLYDYEPIEIGNNIVVYPNWRQPPQDNKHTYIIVDPSIAFGCGNHETTKMCLEWLEQHVSKDTTVLDYGCGTGVL
AIGAVKLGAKYAEGIDIDPNSIESSIKNAQENDVTDKTHFSDNPPTQQFDLVVANIFSNVLISLVGNITTSLKKGGRLAL
SGIIENQVDEVQQEFKKYAITFNQPKQMGQWFLLDGIKNGL
>Mature_281_residues
MQQWHQLEFRLKSKYFDRIENYLFDNDAGSVTRIDKSDDIVSITVLYENHHDIDTIIANIKQKFENIIESEISYEIIKDQ
QWEAAWLYDYEPIEIGNNIVVYPNWRQPPQDNKHTYIIVDPSIAFGCGNHETTKMCLEWLEQHVSKDTTVLDYGCGTGVL
AIGAVKLGAKYAEGIDIDPNSIESSIKNAQENDVTDKTHFSDNPPTQQFDLVVANIFSNVLISLVGNITTSLKKGGRLAL
SGIIENQVDEVQQEFKKYAITFNQPKQMGQWFLLDGIKNGL

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=245, Percent_Identity=31.8367346938775, Blast_Score=125, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32023; Mature: 32023

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQWHQLEFRLKSKYFDRIENYLFDNDAGSVTRIDKSDDIVSITVLYENHHDIDTIIANI
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEEECCCCCHHHHHHHH
KQKFENIIESEISYEIIKDQQWEAAWLYDYEPIEIGNNIVVYPNWRQPPQDNKHTYIIVD
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCEEEEECCCCCCCCCCCCEEEEEC
PSIAFGCGNHETTKMCLEWLEQHVSKDTTVLDYGCGTGVLAIGAVKLGAKYAEGIDIDPN
CCEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCHHHCCCCCCHH
SIESSIKNAQENDVTDKTHFSDNPPTQQFDLVVANIFSNVLISLVGNITTSLKKGGRLAL
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
SGIIENQVDEVQQEFKKYAITFNQPKQMGQWFLLDGIKNGL
HHHHHHHHHHHHHHHHHHEECCCCHHHHCCEEEECCCCCCC
>Mature Secondary Structure
MQQWHQLEFRLKSKYFDRIENYLFDNDAGSVTRIDKSDDIVSITVLYENHHDIDTIIANI
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEEECCCCCHHHHHHHH
KQKFENIIESEISYEIIKDQQWEAAWLYDYEPIEIGNNIVVYPNWRQPPQDNKHTYIIVD
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCEEEEECCCCCCCCCCCCEEEEEC
PSIAFGCGNHETTKMCLEWLEQHVSKDTTVLDYGCGTGVLAIGAVKLGAKYAEGIDIDPN
CCEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCHHHCCCCCCHH
SIESSIKNAQENDVTDKTHFSDNPPTQQFDLVVANIFSNVLISLVGNITTSLKKGGRLAL
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
SGIIENQVDEVQQEFKKYAITFNQPKQMGQWFLLDGIKNGL
HHHHHHHHHHHHHHHHHHEECCCCHHHHCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA