Click here to switch to the map view.

The map label for this gene is pheS [H]

Identifier: 134301906

GI number: 134301906

Start: 876718

End: 877731

Strand: Reverse

Name: pheS [H]

Synonym: FTW_0911

Alternate gene names: 134301906

Gene position: 877731-876718 (Counterclockwise)

Preceding gene: 134301907

Following gene: 134301905

Centisome position: 46.23

GC content: 33.63

Gene sequence:

>1014_bases
ATGCAAATAGTCGAGCAAATGAAAGATAAAGCTCTTGCTGAGCTAAATCTTGTCAAAGATAAAAAAACTTTAGATGATAT
TCGAGTAAAGTACCTGGGTAAAAAGGGTGAATTAACTGAGATGATGAAGTTAATAGCGACATTACCTAATGATGAGAAAC
CAAAGCTAGGACAAGCAGTAAATATTGCAAAACAAGCTTTACAAGAAGCGATCAATTTAAAGCTAGCTAATTTTGAAGAA
CAAGAATTAAATGAAAAACTAGCTCAGGAAAAGATTGATATAACACTAAGTGGAGTAGGGCAAAATCAAGGCTCACTTCA
TCCTGTAACAAAAACACTTAATCGAATTGAAGCATTTTTTAAACAGAATGGTTTTGCTATTGAATTTGGTCCTGAGATTG
AAAGTGATTATTATAATTTTGAAACTTTAAATATCCCTTCTCATCATCCAGCTCGCGCTATGCATGATACTTTTTATATT
GATGAGACTCATGTTTTGAGAACGCACACCTCTGGAGTGCAAATTAGAACTATGGAAAAACAACAGCCACCAATTAGAAT
AATTGCGCCAGGTAGGGTTTATCGTTGTGATTCGGATATTACTCATACACCGATGTTTCATCAAGTAGAAGGTTTACTTG
TAGATAAGGATGTTTCTTTTGCTGATCTTAAAGGCTTGTTGCATGCTTTTCTTAACTCATTTTTTGAAAAAGATCTAAAA
GTAAGATTTAGACCATCTTATTTCCCATTTACTGAGCCTTCAGCAGAGGCTGATATCGAATGTGTAATGTGTGATGGTAA
AGGCTGTAGAGTATGTAAGCATACTGGTTGGTTAGAAGTACTTGGCTGTGGTATGGTGCATCCTAAAGTTTTAAAAGCTG
GAAATATAGATTCTGAAAAATATCAAGGATTTGCTTTTGGCATGGGTGTTGAAAGATTATCTATGCTTAGATATGGTATA
GATGATCTAAGAATGTTTTTTGAAAATGATTTGAGATTTTTAAAACAGTTTTAA

Upstream 100 bases:

>100_bases
AAAAAAACTAACTAAAACCTTTAAAGTTTGTTACTCGCAACATTTTAATAAAAGTCTTTTTTGTCTATAATATCAGCAAG
TTTTGAAATAAAGGATAAAT

Downstream 100 bases:

>100_bases
TTATTATTTGAGGTTTATAAATGAAATTTTCACACAATTGGTTAAATGAATATCTAGGTGATACTCAGGATAGCCAAAAT
CTAGCAGATACTTTAACTTT

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MQIVEQMKDKALAELNLVKDKKTLDDIRVKYLGKKGELTEMMKLIATLPNDEKPKLGQAVNIAKQALQEAINLKLANFEE
QELNEKLAQEKIDITLSGVGQNQGSLHPVTKTLNRIEAFFKQNGFAIEFGPEIESDYYNFETLNIPSHHPARAMHDTFYI
DETHVLRTHTSGVQIRTMEKQQPPIRIIAPGRVYRCDSDITHTPMFHQVEGLLVDKDVSFADLKGLLHAFLNSFFEKDLK
VRFRPSYFPFTEPSAEADIECVMCDGKGCRVCKHTGWLEVLGCGMVHPKVLKAGNIDSEKYQGFAFGMGVERLSMLRYGI
DDLRMFFENDLRFLKQF

Sequences:

>Translated_337_residues
MQIVEQMKDKALAELNLVKDKKTLDDIRVKYLGKKGELTEMMKLIATLPNDEKPKLGQAVNIAKQALQEAINLKLANFEE
QELNEKLAQEKIDITLSGVGQNQGSLHPVTKTLNRIEAFFKQNGFAIEFGPEIESDYYNFETLNIPSHHPARAMHDTFYI
DETHVLRTHTSGVQIRTMEKQQPPIRIIAPGRVYRCDSDITHTPMFHQVEGLLVDKDVSFADLKGLLHAFLNSFFEKDLK
VRFRPSYFPFTEPSAEADIECVMCDGKGCRVCKHTGWLEVLGCGMVHPKVLKAGNIDSEKYQGFAFGMGVERLSMLRYGI
DDLRMFFENDLRFLKQF
>Mature_337_residues
MQIVEQMKDKALAELNLVKDKKTLDDIRVKYLGKKGELTEMMKLIATLPNDEKPKLGQAVNIAKQALQEAINLKLANFEE
QELNEKLAQEKIDITLSGVGQNQGSLHPVTKTLNRIEAFFKQNGFAIEFGPEIESDYYNFETLNIPSHHPARAMHDTFYI
DETHVLRTHTSGVQIRTMEKQQPPIRIIAPGRVYRCDSDITHTPMFHQVEGLLVDKDVSFADLKGLLHAFLNSFFEKDLK
VRFRPSYFPFTEPSAEADIECVMCDGKGCRVCKHTGWLEVLGCGMVHPKVLKAGNIDSEKYQGFAFGMGVERLSMLRYGI
DDLRMFFENDLRFLKQF

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI5729820, Length=292, Percent_Identity=32.5342465753425, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI4758340, Length=273, Percent_Identity=28.9377289377289, Blast_Score=113, Evalue=3e-25,
Organism=Escherichia coli, GI1788007, Length=337, Percent_Identity=59.0504451038576, Blast_Score=421, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI32566635, Length=252, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17508957, Length=275, Percent_Identity=28.7272727272727, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI32563657, Length=275, Percent_Identity=28.7272727272727, Blast_Score=118, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6321087, Length=278, Percent_Identity=28.7769784172662, Blast_Score=119, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6325304, Length=102, Percent_Identity=41.1764705882353, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI17137424, Length=303, Percent_Identity=29.3729372937294, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI18858079, Length=277, Percent_Identity=27.7978339350181, Blast_Score=111, Evalue=6e-25,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 38478; Mature: 38478

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIVEQMKDKALAELNLVKDKKTLDDIRVKYLGKKGELTEMMKLIATLPNDEKPKLGQAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHH
NIAKQALQEAINLKLANFEEQELNEKLAQEKIDITLSGVGQNQGSLHPVTKTLNRIEAFF
HHHHHHHHHHHCCEECCCCHHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHH
KQNGFAIEFGPEIESDYYNFETLNIPSHHPARAMHDTFYIDETHVLRTHTSGVQIRTMEK
HCCCEEEEECCCCCCCCCCEEEECCCCCCCCHHHHCEEEECCCEEEEECCCCEEEEEECC
QQPPIRIIAPGRVYRCDSDITHTPMFHQVEGLLVDKDVSFADLKGLLHAFLNSFFEKDLK
CCCCEEEECCCEEEECCCCCCCCCHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCCE
VRFRPSYFPFTEPSAEADIECVMCDGKGCRVCKHTGWLEVLGCGMVHPKVLKAGNIDSEK
EEECCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCHHHHHCCCCCCHHHHCCCCCCHHH
YQGFAFGMGVERLSMLRYGIDDLRMFFENDLRFLKQF
HCCEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQIVEQMKDKALAELNLVKDKKTLDDIRVKYLGKKGELTEMMKLIATLPNDEKPKLGQAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHH
NIAKQALQEAINLKLANFEEQELNEKLAQEKIDITLSGVGQNQGSLHPVTKTLNRIEAFF
HHHHHHHHHHHCCEECCCCHHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHH
KQNGFAIEFGPEIESDYYNFETLNIPSHHPARAMHDTFYIDETHVLRTHTSGVQIRTMEK
HCCCEEEEECCCCCCCCCCEEEECCCCCCCCHHHHCEEEECCCEEEEECCCCEEEEEECC
QQPPIRIIAPGRVYRCDSDITHTPMFHQVEGLLVDKDVSFADLKGLLHAFLNSFFEKDLK
CCCCEEEECCCEEEECCCCCCCCCHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCCE
VRFRPSYFPFTEPSAEADIECVMCDGKGCRVCKHTGWLEVLGCGMVHPKVLKAGNIDSEK
EEECCCCCCCCCCCCCCCEEEEEECCCCCEEECCCCHHHHHCCCCCCHHHHCCCCCCHHH
YQGFAFGMGVERLSMLRYGIDDLRMFFENDLRFLKQF
HCCEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA