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The map label for this gene is rpe [H]

Identifier: 134301646

GI number: 134301646

Start: 578026

End: 578694

Strand: Direct

Name: rpe [H]

Synonym: FTW_0586

Alternate gene names: 134301646

Gene position: 578026-578694 (Clockwise)

Preceding gene: 134301644

Following gene: 134301647

Centisome position: 30.45

GC content: 36.92

Gene sequence:

>669_bases
ATGAAACATATTCAAATTAATCCTTCTATACTCTCTGCAGATCTTGCCAGATTAGGGGATGATGTCAAGGCAGTTTTAGC
GGCAGGGGCTGATAATATTCATTTTGATGTTATGGATAATCACTATGTGCCTAATCTAACATTTGGACCGATGGTGCTCA
AGGCTTTGAGAGATTATGGTATAACTGCTGGCATGGATGTTCACCTTATGGTTAAACCTGTAGATGCTTTAATTGAGAGT
TTTGCCAAAGCTGGAGCAACTAGTATTGTTTTTCATCCAGAGGCGAGTGAGCATATTGATAGAAGCTTACAACTAATCAA
ATCTTTTGGCATTCAAGCTGGGCTTGCTTTAAATCCTGCTACAGGTATAGATTGTTTGAAGTATGTTGAGAGTAATATTG
ATAGGGTGCTGATAATGTCAGTAAACCCTGGTTTTGGGGGACAAAAATTTATTCCAGCTATGCTTGATAAGGCTAAAGAA
ATTTCTAAATGGATTAGCTCAACTGATAGAGATATTTTGCTAGAGATAGATGGTGGCGTAAATCCGTATAATATTGCTGA
AATAGCTGTATGTGGAGTAAATGCCTTTGTTGCTGGTTCAGCTATTTTTAATTCTGATAGCTATAAGCAAACTATTGATA
AGATGAGAGATGAGCTCAATAAAGTCTAA

Upstream 100 bases:

>100_bases
AAACTAAGGTTTATAGACACAAATTTATATTTTATATAACCAAATTTTACTTTCAATATGATAGAATTTTCAAGTATATT
AAGATATTTAAATTAGCTAT

Downstream 100 bases:

>100_bases
TTTAGTGATCATTCTCAAAACAATAGAGCTAGTAATATCTGTAATACTTGTATTACTAAGTTACTCTATACCTTTGCATC
TACTAAATTATGATACTAGT

Product: D-ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKHIQINPSILSADLARLGDDVKAVLAAGADNIHFDVMDNHYVPNLTFGPMVLKALRDYGITAGMDVHLMVKPVDALIES
FAKAGATSIVFHPEASEHIDRSLQLIKSFGIQAGLALNPATGIDCLKYVESNIDRVLIMSVNPGFGGQKFIPAMLDKAKE
ISKWISSTDRDILLEIDGGVNPYNIAEIAVCGVNAFVAGSAIFNSDSYKQTIDKMRDELNKV

Sequences:

>Translated_222_residues
MKHIQINPSILSADLARLGDDVKAVLAAGADNIHFDVMDNHYVPNLTFGPMVLKALRDYGITAGMDVHLMVKPVDALIES
FAKAGATSIVFHPEASEHIDRSLQLIKSFGIQAGLALNPATGIDCLKYVESNIDRVLIMSVNPGFGGQKFIPAMLDKAKE
ISKWISSTDRDILLEIDGGVNPYNIAEIAVCGVNAFVAGSAIFNSDSYKQTIDKMRDELNKV
>Mature_222_residues
MKHIQINPSILSADLARLGDDVKAVLAAGADNIHFDVMDNHYVPNLTFGPMVLKALRDYGITAGMDVHLMVKPVDALIES
FAKAGATSIVFHPEASEHIDRSLQLIKSFGIQAGLALNPATGIDCLKYVESNIDRVLIMSVNPGFGGQKFIPAMLDKAKE
ISKWISSTDRDILLEIDGGVNPYNIAEIAVCGVNAFVAGSAIFNSDSYKQTIDKMRDELNKV

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=214, Percent_Identity=39.2523364485981, Blast_Score=158, Evalue=3e-39,
Organism=Homo sapiens, GI219879828, Length=214, Percent_Identity=37.8504672897196, Blast_Score=145, Evalue=2e-35,
Organism=Homo sapiens, GI24307923, Length=169, Percent_Identity=31.9526627218935, Blast_Score=94, Evalue=9e-20,
Organism=Escherichia coli, GI1789788, Length=222, Percent_Identity=63.963963963964, Blast_Score=290, Evalue=8e-80,
Organism=Escherichia coli, GI1790523, Length=203, Percent_Identity=34.4827586206897, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1790754, Length=210, Percent_Identity=27.6190476190476, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17552948, Length=216, Percent_Identity=40.2777777777778, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6322341, Length=228, Percent_Identity=36.4035087719298, Blast_Score=152, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24586301, Length=213, Percent_Identity=38.9671361502347, Blast_Score=154, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24044; Mature: 24044

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHIQINPSILSADLARLGDDVKAVLAAGADNIHFDVMDNHYVPNLTFGPMVLKALRDYG
CCEEEECHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCC
ITAGMDVHLMVKPVDALIESFAKAGATSIVFHPEASEHIDRSLQLIKSFGIQAGLALNPA
CCCCCEEEEEECCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCEECCC
TGIDCLKYVESNIDRVLIMSVNPGFGGQKFIPAMLDKAKEISKWISSTDRDILLEIDGGV
CHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
NPYNIAEIAVCGVNAFVAGSAIFNSDSYKQTIDKMRDELNKV
CCCCHHHHEEECCHHHHHCCHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKHIQINPSILSADLARLGDDVKAVLAAGADNIHFDVMDNHYVPNLTFGPMVLKALRDYG
CCEEEECHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCC
ITAGMDVHLMVKPVDALIESFAKAGATSIVFHPEASEHIDRSLQLIKSFGIQAGLALNPA
CCCCCEEEEEECCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCEECCC
TGIDCLKYVESNIDRVLIMSVNPGFGGQKFIPAMLDKAKEISKWISSTDRDILLEIDGGV
CHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
NPYNIAEIAVCGVNAFVAGSAIFNSDSYKQTIDKMRDELNKV
CCCCHHHHEEECCHHHHHCCHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]