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The map label for this gene is rnhB

Identifier: 134301623

GI number: 134301623

Start: 558378

End: 558941

Strand: Direct

Name: rnhB

Synonym: FTW_0562

Alternate gene names: 134301623

Gene position: 558378-558941 (Clockwise)

Preceding gene: 134301622

Following gene: 134301624

Centisome position: 29.41

GC content: 31.91

Gene sequence:

>564_bases
ATGATTATACTAGGTATAGATGAAGCAGGGCGTGGACCATTATCAGGGCCTGTAGTTGCTGCAGGAGTTATATTGGATCA
AGATAAAATTATTGATGGTCTTGCTGATTCAAAGAAGTTAACTGAAAAAAAACGTCAATCACTCTATCAGCAAATAATAA
CTCACGCAAAGGCTTACACAATAGTTGAAATTAGCCCTCAGCAAATCGATGAGTTAAATATCCTTCAAGCAACATTAAAA
GCTATGCATCAAGTTGCAAATAATTTAGAAAGACAGTTTGATAAAGTCTTAGTTGATGGTAATAAATTACCAAATTGGGA
TTATAATTCAGAAGCTATAGTAAAAGGAGACTCAAAAATTATAGAAATATCTGCAGCTTCGATATTGGCAAAGGTGCATA
GAGATAATATCTGTCTTGAGCATGATAGATTATATCCACAATATGGTTTTGCTAAACATAAGGGTTATCCAACAAAAGAG
CATTTAGAGAATATAAAAAAATATGGTGTATTAGATATCCATAGGAAAAGTTATAAACCAGTACAAGTGTTATTAAATGA
ATAA

Upstream 100 bases:

>100_bases
GATAAAGTGCGCAGACTTTTTCAAAGATCCGAACTTGAGAGTCAAGAAGTGAATATTTTGAGAGGTTTTTTAACCTCATT
AGAAAATCAGGATAAGTAGT

Downstream 100 bases:

>100_bases
CTCTGAAAACTACTACACAGCAGGAAAGAGTTTAGGGCTTTTTGCTCTTACAGCTACTCTTGTAATGACAGAGTTAAATA
TATCGACTTTAGTAGGTTTC

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MIILGIDEAGRGPLSGPVVAAGVILDQDKIIDGLADSKKLTEKKRQSLYQQIITHAKAYTIVEISPQQIDELNILQATLK
AMHQVANNLERQFDKVLVDGNKLPNWDYNSEAIVKGDSKIIEISAASILAKVHRDNICLEHDRLYPQYGFAKHKGYPTKE
HLENIKKYGVLDIHRKSYKPVQVLLNE

Sequences:

>Translated_187_residues
MIILGIDEAGRGPLSGPVVAAGVILDQDKIIDGLADSKKLTEKKRQSLYQQIITHAKAYTIVEISPQQIDELNILQATLK
AMHQVANNLERQFDKVLVDGNKLPNWDYNSEAIVKGDSKIIEISAASILAKVHRDNICLEHDRLYPQYGFAKHKGYPTKE
HLENIKKYGVLDIHRKSYKPVQVLLNE
>Mature_187_residues
MIILGIDEAGRGPLSGPVVAAGVILDQDKIIDGLADSKKLTEKKRQSLYQQIITHAKAYTIVEISPQQIDELNILQATLK
AMHQVANNLERQFDKVLVDGNKLPNWDYNSEAIVKGDSKIIEISAASILAKVHRDNICLEHDRLYPQYGFAKHKGYPTKE
HLENIKKYGVLDIHRKSYKPVQVLLNE

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=185, Percent_Identity=49.7297297297297, Blast_Score=185, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_FRAT1 (Q14GW0)

Other databases:

- EMBL:   AM286280
- RefSeq:   YP_667366.1
- ProteinModelPortal:   Q14GW0
- SMR:   Q14GW0
- STRING:   Q14GW0
- GeneID:   4200767
- GenomeReviews:   AM286280_GR
- KEGG:   ftf:FTF1278c
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- PhylomeDB:   Q14GW0
- ProtClustDB:   PRK00015
- BioCyc:   FTUL393115:FTF1278C-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 21050; Mature: 21050

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILGIDEAGRGPLSGPVVAAGVILDQDKIIDGLADSKKLTEKKRQSLYQQIITHAKAYT
CEEEECCCCCCCCCCCCCEEHHEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEE
IVEISPQQIDELNILQATLKAMHQVANNLERQFDKVLVDGNKLPNWDYNSEAIVKGDSKI
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCEE
IEISAASILAKVHRDNICLEHDRLYPQYGFAKHKGYPTKEHLENIKKYGVLDIHRKSYKP
EEEHHHHHHHHHHHCCEEEECCCCCCCCCCHHCCCCCCHHHHHHHHHCCCEEECCCCCCC
VQVLLNE
CEEEECC
>Mature Secondary Structure
MIILGIDEAGRGPLSGPVVAAGVILDQDKIIDGLADSKKLTEKKRQSLYQQIITHAKAYT
CEEEECCCCCCCCCCCCCEEHHEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEE
IVEISPQQIDELNILQATLKAMHQVANNLERQFDKVLVDGNKLPNWDYNSEAIVKGDSKI
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCEE
IEISAASILAKVHRDNICLEHDRLYPQYGFAKHKGYPTKEHLENIKKYGVLDIHRKSYKP
EEEHHHHHHHHHHHCCEEEECCCCCCCCCCHHCCCCCCHHHHHHHHHCCCEEECCCCCCC
VQVLLNE
CEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA