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The map label for this gene is pgk

Identifier: 134301591

GI number: 134301591

Start: 511227

End: 512405

Strand: Direct

Name: pgk

Synonym: FTW_0524

Alternate gene names: 134301591

Gene position: 511227-512405 (Clockwise)

Preceding gene: 134301590

Following gene: 134301592

Centisome position: 26.93

GC content: 36.73

Gene sequence:

>1179_bases
ATGAGTTTTCTAACATTGAAAGATGTTGATTTAAAAGATAAAAAAGTCTTGGTTCGTGTTGACTTCAACGTACCTGTTAA
AGATGGTAAGGTAACAAGTAAAGTTAGAATTGAAGCGGCTATTCCGACTATTCAATATATTCTAGATCAAGGTGGAGCTG
TGATTCTGATGTCACACCTTGGTCGTCCTACAGAGGGTGAGTATGATTCTCAGTTCTCTCTAGAGCCTGTTGCTAAAGCT
TTATCTGAAATTATCAATAAGCCGGTTAAGTTTGCTAAAGACTGGTTAGATGGTGTTGATGTTAAAGCTGGTGAAATTGT
CATGTGTGAAAATGTCCGCTTTAATAGTGGTGAGAAAAAATCAACAGATGATTTATCTAAAAAGATTGCAAGCTTAGGTG
ATGTGTTTGTTATGGACGCTTTTGCTACAGCGCATAGAGCTCAAGCTTCGACCTACGGTGTTGCTAAGTATATTCCTGTA
GCATGTGCAGGGATATTGTTAACTAATGAAATTCAAGCATTAGAAAAAGCTTTAAAATCGCCAAAAAAACCAATGGCAGC
AATAGTTGGAGGGTCTAAGGTCTCTACTAAACTATCGGTGCTAAATAACCTTCTTGATAAGGTTGAAATTCTTATTGTTG
GTGGTGGTATTGCTAATACTTTCATAAAAGCAGAAGGTTTTGATGTTGGTAATTCATTGTATGAACAAGATCTTGTCGCT
GAAGCAACAGAGATTTTAGCTAAAGCTAAAGCTTTAGGGGTTAATATTCCTGTGCCAGTTGATGTAAGAGTTGCTAAAGA
GTTTAGCGAAAATGCCCAAGCAATCATTAAAAAGGTTTCCGATGTTGTTGCGGATGAGATGATTCTAGATATAGGTCCAG
AATCTCAAAAGATAATTGCTGAGCTGTTAAAATCAGCAAATACTATCTTATGGAATGGACCTGTTGGAGTATTTGAGTTT
GATAACTTTGCAGAGGGTACAAAAGCTTTATCTTTAGCTATAGCACAATCGCACGCTTTTTCAGTAGCTGGTGGTGGTGA
TACTATTGCTGCGATAGAAAAATTTGGCATTAAAGACCAAGTTTCTTATATATCAACAGCTGGTGGAGCATTCTTAGAGT
TTCTTGAAGGCAAGAAATTACCAGCTATAGAGATACTTAAAGAAAAAGCAATCAGGTAA

Upstream 100 bases:

>100_bases
TAAAGTAGTATCTTGGTATGACAATGAAATGTCTTATACAAATCAAATGGTTAGAGTAGTAGAGTACTTCGGAGCTCTAT
AAACATTATAGGTGATATAA

Downstream 100 bases:

>100_bases
TTTAGGATAATTTATATGAGAAGAACAAAAATTTTAGCTACTCTTGGTCCTGCTAGTGAATCAAGAGAAGCTCTAACAGA
GATGATTAAAGCAGGGGTTA

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSFLTLKDVDLKDKKVLVRVDFNVPVKDGKVTSKVRIEAAIPTIQYILDQGGAVILMSHLGRPTEGEYDSQFSLEPVAKA
LSEIINKPVKFAKDWLDGVDVKAGEIVMCENVRFNSGEKKSTDDLSKKIASLGDVFVMDAFATAHRAQASTYGVAKYIPV
ACAGILLTNEIQALEKALKSPKKPMAAIVGGSKVSTKLSVLNNLLDKVEILIVGGGIANTFIKAEGFDVGNSLYEQDLVA
EATEILAKAKALGVNIPVPVDVRVAKEFSENAQAIIKKVSDVVADEMILDIGPESQKIIAELLKSANTILWNGPVGVFEF
DNFAEGTKALSLAIAQSHAFSVAGGGDTIAAIEKFGIKDQVSYISTAGGAFLEFLEGKKLPAIEILKEKAIR

Sequences:

>Translated_392_residues
MSFLTLKDVDLKDKKVLVRVDFNVPVKDGKVTSKVRIEAAIPTIQYILDQGGAVILMSHLGRPTEGEYDSQFSLEPVAKA
LSEIINKPVKFAKDWLDGVDVKAGEIVMCENVRFNSGEKKSTDDLSKKIASLGDVFVMDAFATAHRAQASTYGVAKYIPV
ACAGILLTNEIQALEKALKSPKKPMAAIVGGSKVSTKLSVLNNLLDKVEILIVGGGIANTFIKAEGFDVGNSLYEQDLVA
EATEILAKAKALGVNIPVPVDVRVAKEFSENAQAIIKKVSDVVADEMILDIGPESQKIIAELLKSANTILWNGPVGVFEF
DNFAEGTKALSLAIAQSHAFSVAGGGDTIAAIEKFGIKDQVSYISTAGGAFLEFLEGKKLPAIEILKEKAIR
>Mature_391_residues
SFLTLKDVDLKDKKVLVRVDFNVPVKDGKVTSKVRIEAAIPTIQYILDQGGAVILMSHLGRPTEGEYDSQFSLEPVAKAL
SEIINKPVKFAKDWLDGVDVKAGEIVMCENVRFNSGEKKSTDDLSKKIASLGDVFVMDAFATAHRAQASTYGVAKYIPVA
CAGILLTNEIQALEKALKSPKKPMAAIVGGSKVSTKLSVLNNLLDKVEILIVGGGIANTFIKAEGFDVGNSLYEQDLVAE
ATEILAKAKALGVNIPVPVDVRVAKEFSENAQAIIKKVSDVVADEMILDIGPESQKIIAELLKSANTILWNGPVGVFEFD
NFAEGTKALSLAIAQSHAFSVAGGGDTIAAIEKFGIKDQVSYISTAGGAFLEFLEGKKLPAIEILKEKAIR

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family

Homologues:

Organism=Homo sapiens, GI4505763, Length=413, Percent_Identity=42.3728813559322, Blast_Score=306, Evalue=2e-83,
Organism=Homo sapiens, GI31543397, Length=411, Percent_Identity=42.5790754257908, Blast_Score=302, Evalue=4e-82,
Organism=Escherichia coli, GI1789294, Length=390, Percent_Identity=63.0769230769231, Blast_Score=487, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI17508823, Length=414, Percent_Identity=43.9613526570048, Blast_Score=321, Evalue=3e-88,
Organism=Saccharomyces cerevisiae, GI6319857, Length=416, Percent_Identity=43.5096153846154, Blast_Score=306, Evalue=5e-84,
Organism=Drosophila melanogaster, GI24581203, Length=413, Percent_Identity=38.9830508474576, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI17136394, Length=416, Percent_Identity=39.9038461538462, Blast_Score=271, Evalue=5e-73,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): PGK_FRAT1 (Q14GM9)

Other databases:

- EMBL:   AM286280
- RefSeq:   YP_667448.1
- ProteinModelPortal:   Q14GM9
- SMR:   Q14GM9
- STRING:   Q14GM9
- GeneID:   4199243
- GenomeReviews:   AM286280_GR
- KEGG:   ftf:FTF1367c
- eggNOG:   COG0126
- HOGENOM:   HBG453500
- OMA:   NCAIILP
- PhylomeDB:   Q14GM9
- ProtClustDB:   PRK00073
- BioCyc:   FTUL393115:FTF1367C-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00145
- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824
- Gene3D:   G3DSA:3.40.50.1270
- Gene3D:   G3DSA:3.40.50.1260
- PANTHER:   PTHR11406
- PIRSF:   PIRSF000724
- PRINTS:   PR00477

Pfam domain/function: PF00162 PGK; SSF53748 PGK

EC number: =2.7.2.3

Molecular weight: Translated: 41937; Mature: 41806

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: BINDING 36-36 BINDING 113-113 BINDING 146-146 BINDING 197-197 BINDING 319-319

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLTLKDVDLKDKKVLVRVDFNVPVKDGKVTSKVRIEAAIPTIQYILDQGGAVILMSHL
CCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCEEEEEECC
GRPTEGEYDSQFSLEPVAKALSEIINKPVKFAKDWLDGVDVKAGEIVMCENVRFNSGEKK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCC
STDDLSKKIASLGDVFVMDAFATAHRAQASTYGVAKYIPVACAGILLTNEIQALEKALKS
CHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PKKPMAAIVGGSKVSTKLSVLNNLLDKVEILIVGGGIANTFIKAEGFDVGNSLYEQDLVA
CCCCCEEEECCCHHHHHHHHHHHHHHHEEEEEECCCHHHHEEEECCCCCCHHHHHHHHHH
EATEILAKAKALGVNIPVPVDVRVAKEFSENAQAIIKKVSDVVADEMILDIGPESQKIIA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHH
ELLKSANTILWNGPVGVFEFDNFAEGTKALSLAIAQSHAFSVAGGGDTIAAIEKFGIKDQ
HHHHCCCEEEECCCCCEEECCCCCCHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCHHH
VSYISTAGGAFLEFLEGKKLPAIEILKEKAIR
HHHHHHCHHHHHHHHCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
SFLTLKDVDLKDKKVLVRVDFNVPVKDGKVTSKVRIEAAIPTIQYILDQGGAVILMSHL
CCEEEECCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEHHHHHHHHHHCCCEEEEEECC
GRPTEGEYDSQFSLEPVAKALSEIINKPVKFAKDWLDGVDVKAGEIVMCENVRFNSGEKK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCC
STDDLSKKIASLGDVFVMDAFATAHRAQASTYGVAKYIPVACAGILLTNEIQALEKALKS
CHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
PKKPMAAIVGGSKVSTKLSVLNNLLDKVEILIVGGGIANTFIKAEGFDVGNSLYEQDLVA
CCCCCEEEECCCHHHHHHHHHHHHHHHEEEEEECCCHHHHEEEECCCCCCHHHHHHHHHH
EATEILAKAKALGVNIPVPVDVRVAKEFSENAQAIIKKVSDVVADEMILDIGPESQKIIA
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHH
ELLKSANTILWNGPVGVFEFDNFAEGTKALSLAIAQSHAFSVAGGGDTIAAIEKFGIKDQ
HHHHCCCEEEECCCCCEEECCCCCCHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCHHH
VSYISTAGGAFLEFLEGKKLPAIEILKEKAIR
HHHHHHCHHHHHHHHCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA