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The map label for this gene is coaX1

Identifier: 134301567

GI number: 134301567

Start: 488184

End: 488954

Strand: Reverse

Name: coaX1

Synonym: FTW_0496

Alternate gene names: 134301567

Gene position: 488954-488184 (Counterclockwise)

Preceding gene: 134301568

Following gene: 134301560

Centisome position: 25.76

GC content: 34.5

Gene sequence:

>771_bases
ATGATAGTATGTATAGATATTGGTAACTCACATATTTTTGGTGGAGTATTTGTAGGAGATCAAATTAAGCATAACTTTCG
CTACCCTTCTACTACTCCGTGTACTTCTGATACGCTAGGTATATTTCTGCTATCGTTCTTTGAGAGGAAAAAGCTTGATA
TCGAAGATATTGAAGCAGTTGTACTTTCATCTGTTGTTCTTCATCTAGAGTATTCTGTCAATTCCGCTTGCAAAAAGTAT
TTAGGTATAACTCCGCTTGAGCTAAAACCTGGGGTAAAAACAGGATTAAAACTCGATATCAAAAATCCTCTAGATTTAGG
TGCAGATCGTGTTGCAAACTCAGTTGCAGCTATTTCTCTTTTTCCATCGAGAAATATTATTGTAGTTGACTTTGGCACAG
CAACAACTATTTGTGCTATTTCAGAGAATAAAACCTATATCGGCGGTGCTATCCTACCAGGAATTAACCTATCAATGGAG
AGCTTATCACAAAAAACTGCAAAACTATCTAATGTAACTATCTCTCACCCTAGTTCTGCGTTAGGTAAGACAACTATCTC
TCAAATCCAATCGGGTCTTATATATGGTCAATTAGGTGCTATAAAAGAGATAATTAATCGAATATCTCAAGAAAACTTCA
TAGATAAACCACCAATATTAATAGCAACTGGAGGCTATGCTCATATTTTTGAGAAAGAACAATATTTTGATGTAATCATC
TCTGATTTATTACTTCATGGACTTAGAATAATCTGGCAAATGAATAAGTAA

Upstream 100 bases:

>100_bases
AATAGGTGATCAGCTGTTTATAATTAGTTATACACAAGTTGATCCTACTAGAGAAAATATAAAACCTAAACTTGTTGATC
TAAAAACCGGAGATTAATAA

Downstream 100 bases:

>100_bases
TTTCTAAGTTATTGAGTGCTCAAGCTAACTAATTCACTGATATTTGAATTTCTCTTAATATCTTTCTGAGCAATATCTCT
TAAGCTACTTTGTTCAGATA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III 1; Pantothenic acid kinase 1

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MIVCIDIGNSHIFGGVFVGDQIKHNFRYPSTTPCTSDTLGIFLLSFFERKKLDIEDIEAVVLSSVVLHLEYSVNSACKKY
LGITPLELKPGVKTGLKLDIKNPLDLGADRVANSVAAISLFPSRNIIVVDFGTATTICAISENKTYIGGAILPGINLSME
SLSQKTAKLSNVTISHPSSALGKTTISQIQSGLIYGQLGAIKEIINRISQENFIDKPPILIATGGYAHIFEKEQYFDVII
SDLLLHGLRIIWQMNK

Sequences:

>Translated_256_residues
MIVCIDIGNSHIFGGVFVGDQIKHNFRYPSTTPCTSDTLGIFLLSFFERKKLDIEDIEAVVLSSVVLHLEYSVNSACKKY
LGITPLELKPGVKTGLKLDIKNPLDLGADRVANSVAAISLFPSRNIIVVDFGTATTICAISENKTYIGGAILPGINLSME
SLSQKTAKLSNVTISHPSSALGKTTISQIQSGLIYGQLGAIKEIINRISQENFIDKPPILIATGGYAHIFEKEQYFDVII
SDLLLHGLRIIWQMNK
>Mature_256_residues
MIVCIDIGNSHIFGGVFVGDQIKHNFRYPSTTPCTSDTLGIFLLSFFERKKLDIEDIEAVVLSSVVLHLEYSVNSACKKY
LGITPLELKPGVKTGLKLDIKNPLDLGADRVANSVAAISLFPSRNIIVVDFGTATTICAISENKTYIGGAILPGINLSME
SLSQKTAKLSNVTISHPSSALGKTTISQIQSGLIYGQLGAIKEIINRISQENFIDKPPILIATGGYAHIFEKEQYFDVII
SDLLLHGLRIIWQMNK

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX1_FRATH (Q2A4C9)

Other databases:

- EMBL:   AM233362
- RefSeq:   YP_513423.1
- ProteinModelPortal:   Q2A4C9
- SMR:   Q2A4C9
- GeneID:   3952542
- GenomeReviews:   AM233362_GR
- KEGG:   ftl:FTL_0671
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13321
- BioCyc:   FTUL351581:FTL_0671-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27923; Mature: 27923

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 133-133 BINDING 185-185

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVCIDIGNSHIFGGVFVGDQIKHNFRYPSTTPCTSDTLGIFLLSFFERKKLDIEDIEAV
CEEEEEECCCEEEEEEEECCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
VLSSVVLHLEYSVNSACKKYLGITPLELKPGVKTGLKLDIKNPLDLGADRVANSVAAISL
HHHHHHHHEECCHHHHHHHHHCCCCEEECCCCCCCEEEEECCCCCCCHHHHHHHEEEEEE
FPSRNIIVVDFGTATTICAISENKTYIGGAILPGINLSMESLSQKTAKLSNVTISHPSSA
ECCCCEEEEECCCCEEEEEEECCCEEECCEECCCCCCCHHHHHHHHHHHHCEEEECCCHH
LGKTTISQIQSGLIYGQLGAIKEIINRISQENFIDKPPILIATGGYAHIFEKEQYFDVII
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEECCHHHHHHHHH
SDLLLHGLRIIWQMNK
HHHHHHHHHHHEEECC
>Mature Secondary Structure
MIVCIDIGNSHIFGGVFVGDQIKHNFRYPSTTPCTSDTLGIFLLSFFERKKLDIEDIEAV
CEEEEEECCCEEEEEEEECCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHH
VLSSVVLHLEYSVNSACKKYLGITPLELKPGVKTGLKLDIKNPLDLGADRVANSVAAISL
HHHHHHHHEECCHHHHHHHHHCCCCEEECCCCCCCEEEEECCCCCCCHHHHHHHEEEEEE
FPSRNIIVVDFGTATTICAISENKTYIGGAILPGINLSMESLSQKTAKLSNVTISHPSSA
ECCCCEEEEECCCCEEEEEEECCCEEECCEECCCCCCCHHHHHHHHHHHHCEEEECCCHH
LGKTTISQIQSGLIYGQLGAIKEIINRISQENFIDKPPILIATGGYAHIFEKEQYFDVII
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEECCHHHHHHHHH
SDLLLHGLRIIWQMNK
HHHHHHHHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA