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The map label for this gene is ybdL [H]

Identifier: 134301542

GI number: 134301542

Start: 459179

End: 460312

Strand: Reverse

Name: ybdL [H]

Synonym: FTW_0471

Alternate gene names: 134301542

Gene position: 460312-459179 (Counterclockwise)

Preceding gene: 134301543

Following gene: 134301541

Centisome position: 24.25

GC content: 34.92

Gene sequence:

>1134_bases
ATGATCCAAGCGAAATCTTATATCGACACTACGCCATCTGTATATGGCAAATTTGCTTTGATGGCAAATGAGTATAAAGC
TTTAAATTTTACTCAAGGAGCTCCTGATTTTGATACTCCCGAGTGGTTAATTGAACGTACAAACTTTTATATACAGCATG
GCAAAAACCAATACTCTCCAATTCCAGGAGCTGTCGCACTACGTAATGCAATAGTACAAAAAACTAAACGATGCTATGAC
ACAGATATAACCATCGATAATGTAGCTATTACTGCAGGTGCTCAAGAAGGCTTGTTCTGTATAATTTCTGCTTATGTTGG
TCAAGGTGATGAAGTTATTATGTTTGATCCCATATTTGATACTTATGCCGGAGTCACAAAATTTAATCAAGGTAAATGTG
TCAGACTGAAACTACTACCAAATGGTAAAATTGATATAAACGCTATTGCAAATGCTATTACAAATCGTACTAAACTCATA
ATTCTAAACTCTCCTCATAATCCTATGGGAACAGTTATATCTAAAGATGAATTCAAAGAAATTGCAAAAATTGTCAAAGA
TAAAGACATTTTAGTAATCTCTGATGAAGTTTATGAACATATATACGCAGGAGAGAGTTTTATAAGTGCTATACAAATAC
CAGAGCTACATCATAAGCTAGTAGTGTTCCAATCTCTTGGCAAGACTTACAATGTTACTGGCTGGCGCCAAGGTGTAACA
ATCGCCCCACCACAAGTGATACAGAATATGCTCGCAATAAAACAGTTTGCAACATTCTCTGCAGTACATCCAATGCAATT
AGCCTTAGCTGAGGGGATACTAGAATATCCTGAATATTATGAAAATCTGCATAAACTCTACAAAAAGCAAAATCAGTTAT
TAAGAGAGCACTTAAAAGGTACAAGATTCAAAATCCTTGACTGGCAAGGCTCACCTTTTCAAATTCTTGACTATAGTAAT
ATAAGTAATCAAGATGGTGATAAATTTGCTAGTAATTTGATCAAAGAACATGGTGTTGGTTTAGTGCCAATATCATCACT
TTTTGAGACTCCTCAAGATGGTCTTTTAAGACTATGCTTTGCCAAAAAAGATCACGACATAATCAAAGGAGCTAAAATCC
TAGCGAATATCTAA

Upstream 100 bases:

>100_bases
AAATACTTTTATTATCAACAATAAATCAACGAATAAAGCTAAATTTATCTAACGATTTATACTATAATCTTAACTATTAT
CTTCATAACTAAAAAATATT

Downstream 100 bases:

>100_bases
TGCAAAAAAACTCTAAAATAAATCACCAATACTATCTTAGGTTTTTTGGTAAATTTTGGGTAATTTTAGTGGGAAATATC
AAAAATAGAATTTTTAAATT

Product: aminotransferase, class I/II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MIQAKSYIDTTPSVYGKFALMANEYKALNFTQGAPDFDTPEWLIERTNFYIQHGKNQYSPIPGAVALRNAIVQKTKRCYD
TDITIDNVAITAGAQEGLFCIISAYVGQGDEVIMFDPIFDTYAGVTKFNQGKCVRLKLLPNGKIDINAIANAITNRTKLI
ILNSPHNPMGTVISKDEFKEIAKIVKDKDILVISDEVYEHIYAGESFISAIQIPELHHKLVVFQSLGKTYNVTGWRQGVT
IAPPQVIQNMLAIKQFATFSAVHPMQLALAEGILEYPEYYENLHKLYKKQNQLLREHLKGTRFKILDWQGSPFQILDYSN
ISNQDGDKFASNLIKEHGVGLVPISSLFETPQDGLLRLCFAKKDHDIIKGAKILANI

Sequences:

>Translated_377_residues
MIQAKSYIDTTPSVYGKFALMANEYKALNFTQGAPDFDTPEWLIERTNFYIQHGKNQYSPIPGAVALRNAIVQKTKRCYD
TDITIDNVAITAGAQEGLFCIISAYVGQGDEVIMFDPIFDTYAGVTKFNQGKCVRLKLLPNGKIDINAIANAITNRTKLI
ILNSPHNPMGTVISKDEFKEIAKIVKDKDILVISDEVYEHIYAGESFISAIQIPELHHKLVVFQSLGKTYNVTGWRQGVT
IAPPQVIQNMLAIKQFATFSAVHPMQLALAEGILEYPEYYENLHKLYKKQNQLLREHLKGTRFKILDWQGSPFQILDYSN
ISNQDGDKFASNLIKEHGVGLVPISSLFETPQDGLLRLCFAKKDHDIIKGAKILANI
>Mature_377_residues
MIQAKSYIDTTPSVYGKFALMANEYKALNFTQGAPDFDTPEWLIERTNFYIQHGKNQYSPIPGAVALRNAIVQKTKRCYD
TDITIDNVAITAGAQEGLFCIISAYVGQGDEVIMFDPIFDTYAGVTKFNQGKCVRLKLLPNGKIDINAIANAITNRTKLI
ILNSPHNPMGTVISKDEFKEIAKIVKDKDILVISDEVYEHIYAGESFISAIQIPELHHKLVVFQSLGKTYNVTGWRQGVT
IAPPQVIQNMLAIKQFATFSAVHPMQLALAEGILEYPEYYENLHKLYKKQNQLLREHLKGTRFKILDWQGSPFQILDYSN
ISNQDGDKFASNLIKEHGVGLVPISSLFETPQDGLLRLCFAKKDHDIIKGAKILANI

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=400, Percent_Identity=28.25, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI169881279, Length=400, Percent_Identity=28.25, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI56713254, Length=397, Percent_Identity=27.9596977329975, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI56713256, Length=397, Percent_Identity=27.9596977329975, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI169881281, Length=393, Percent_Identity=24.9363867684478, Blast_Score=129, Evalue=4e-30,
Organism=Escherichia coli, GI1786816, Length=374, Percent_Identity=38.5026737967914, Blast_Score=278, Evalue=4e-76,
Organism=Escherichia coli, GI1788722, Length=275, Percent_Identity=28, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788627, Length=285, Percent_Identity=25.6140350877193, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788332, Length=169, Percent_Identity=26.0355029585799, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787710, Length=233, Percent_Identity=25.7510729613734, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71994476, Length=403, Percent_Identity=26.302729528536, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71994472, Length=405, Percent_Identity=26.1728395061728, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17567369, Length=402, Percent_Identity=27.8606965174129, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17567663, Length=333, Percent_Identity=24.6246246246246, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322401, Length=371, Percent_Identity=27.4932614555256, Blast_Score=148, Evalue=1e-36,
Organism=Drosophila melanogaster, GI28573069, Length=407, Percent_Identity=29.7297297297297, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24646114, Length=407, Percent_Identity=29.7297297297297, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI28573067, Length=407, Percent_Identity=29.7297297297297, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI28573065, Length=407, Percent_Identity=29.7297297297297, Blast_Score=172, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42314; Mature: 42314

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQAKSYIDTTPSVYGKFALMANEYKALNFTQGAPDFDTPEWLIERTNFYIQHGKNQYSP
CCCCCCCCCCCHHHHHEEHEEECCCCEEEECCCCCCCCCHHHHHHHCCEEEECCCCCCCC
IPGAVALRNAIVQKTKRCYDTDITIDNVAITAGAQEGLFCIISAYVGQGDEVIMFDPIFD
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEEHHHCCCCCEEEECCCHH
TYAGVTKFNQGKCVRLKLLPNGKIDINAIANAITNRTKLIILNSPHNPMGTVISKDEFKE
HHHCCCCCCCCCEEEEEECCCCCEEHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHH
IAKIVKDKDILVISDEVYEHIYAGESFISAIQIPELHHKLVVFQSLGKTYNVTGWRQGVT
HHHHHCCCCEEEECHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHCCCEECCCCCCCCCE
IAPPQVIQNMLAIKQFATFSAVHPMQLALAEGILEYPEYYENLHKLYKKQNQLLREHLKG
ECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TRFKILDWQGSPFQILDYSNISNQDGDKFASNLIKEHGVGLVPISSLFETPQDGLLRLCF
CEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEHHHHHCCCHHHHHHHHH
AKKDHDIIKGAKILANI
CCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MIQAKSYIDTTPSVYGKFALMANEYKALNFTQGAPDFDTPEWLIERTNFYIQHGKNQYSP
CCCCCCCCCCCHHHHHEEHEEECCCCEEEECCCCCCCCCHHHHHHHCCEEEECCCCCCCC
IPGAVALRNAIVQKTKRCYDTDITIDNVAITAGAQEGLFCIISAYVGQGDEVIMFDPIFD
CCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEEHHHCCCCCEEEECCCHH
TYAGVTKFNQGKCVRLKLLPNGKIDINAIANAITNRTKLIILNSPHNPMGTVISKDEFKE
HHHCCCCCCCCCEEEEEECCCCCEEHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHH
IAKIVKDKDILVISDEVYEHIYAGESFISAIQIPELHHKLVVFQSLGKTYNVTGWRQGVT
HHHHHCCCCEEEECHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHCCCEECCCCCCCCCE
IAPPQVIQNMLAIKQFATFSAVHPMQLALAEGILEYPEYYENLHKLYKKQNQLLREHLKG
ECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TRFKILDWQGSPFQILDYSNISNQDGDKFASNLIKEHGVGLVPISSLFETPQDGLLRLCF
CEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEHHHHHCCCHHHHHHHHH
AKKDHDIIKGAKILANI
CCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]