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The map label for this gene is coaX1

Identifier: 134301323

GI number: 134301323

Start: 205673

End: 206449

Strand: Direct

Name: coaX1

Synonym: FTW_0197

Alternate gene names: 134301323

Gene position: 205673-206449 (Clockwise)

Preceding gene: 134301322

Following gene: 134301324

Centisome position: 10.83

GC content: 34.49

Gene sequence:

>777_bases
ATGTTATTAGTAATGGATATGGGCAATTCCCATATACACATTGGTGTGTTTGATGGTGATAGAATAGTTTCTCAAATTAG
ATATGCAACATCATCTGTAGACTCGACTTCTGATCAGATGGGTGTATTCCTTCGACAAGCATTAAGGGAAAACTCGGTTG
ATTTAGGTAAAATTGATGGCTGTGGTATATCTTCGGTAGTACCACACTTAAATTATTCTCTTGGTTCAGCTGTTATCAAA
TATTTCAATATTAAGCCATTTTTTATAAGTATGGATACTACAGATTTGGATATGTCAGCAGTTGAAGCACATCAGGTTGG
CGCTGATAGAATAGCAAGTTGTATTAGTGCAATAGCTGATCATCCTAATAAGGATTTGTTGATAATAGATTTAGGTACAG
CAACAACCTTTGATTTAGTAACTAAGGATAAGAAATATTTGAGTGGCTCGATTATGCCGGGAGTTAAACTCTCTTTAAAT
GCTTTGTGTCAAGGTGCTTCGCAATTATCATCGGTGACTATTGTTAAACCTGAGGTTGCTATAGGTTATGATACTAAAAC
AAATATCCGTTCAGGCTTATATTATGGTCATCTAGGTGCATTAAAAGAACTTAAAAGAAGAAGTGTTGAAGAATTTGGTA
GTCCGGTTTATACCATAGCTACTGGTGGATTTGCTGGGTTATTTAAAGAAGAAGATATATTTAATGAGATTTCTCCTGAT
TTGATATTGCGTGGAATTAGAATTGCATTTTTAGAAAATAACAAGAAAGGGGTTTAG

Upstream 100 bases:

>100_bases
ATAATGGAAGCAGCTGTAAAGCTTAATGTGCCTTTAGAGGTGAATGTTGATTCTGGTAAGAGTTGGGATCAAGCTCATTA
AATAATTTATAGGATATTTT

Downstream 100 bases:

>100_bases
GAGTATGTTAAAAGATAAAAAAGTTGTTATCTTACTCTTTGATTCATTTGGTATTGGTCAAGCTCCTGATGCAGCCGATT
TTGGCGATGAAGGTGCTGAT

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III 1; Pantothenic acid kinase 1

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MLLVMDMGNSHIHIGVFDGDRIVSQIRYATSSVDSTSDQMGVFLRQALRENSVDLGKIDGCGISSVVPHLNYSLGSAVIK
YFNIKPFFISMDTTDLDMSAVEAHQVGADRIASCISAIADHPNKDLLIIDLGTATTFDLVTKDKKYLSGSIMPGVKLSLN
ALCQGASQLSSVTIVKPEVAIGYDTKTNIRSGLYYGHLGALKELKRRSVEEFGSPVYTIATGGFAGLFKEEDIFNEISPD
LILRGIRIAFLENNKKGV

Sequences:

>Translated_258_residues
MLLVMDMGNSHIHIGVFDGDRIVSQIRYATSSVDSTSDQMGVFLRQALRENSVDLGKIDGCGISSVVPHLNYSLGSAVIK
YFNIKPFFISMDTTDLDMSAVEAHQVGADRIASCISAIADHPNKDLLIIDLGTATTFDLVTKDKKYLSGSIMPGVKLSLN
ALCQGASQLSSVTIVKPEVAIGYDTKTNIRSGLYYGHLGALKELKRRSVEEFGSPVYTIATGGFAGLFKEEDIFNEISPD
LILRGIRIAFLENNKKGV
>Mature_258_residues
MLLVMDMGNSHIHIGVFDGDRIVSQIRYATSSVDSTSDQMGVFLRQALRENSVDLGKIDGCGISSVVPHLNYSLGSAVIK
YFNIKPFFISMDTTDLDMSAVEAHQVGADRIASCISAIADHPNKDLLIIDLGTATTFDLVTKDKKYLSGSIMPGVKLSLN
ALCQGASQLSSVTIVKPEVAIGYDTKTNIRSGLYYGHLGALKELKRRSVEEFGSPVYTIATGGFAGLFKEEDIFNEISPD
LILRGIRIAFLENNKKGV

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX1_FRAT1 (Q14JW3)

Other databases:

- EMBL:   AM286280
- RefSeq:   YP_666313.1
- ProteinModelPortal:   Q14JW3
- SMR:   Q14JW3
- STRING:   Q14JW3
- GeneID:   4200541
- GenomeReviews:   AM286280_GR
- KEGG:   ftf:FTF0112
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   VADYPID
- ProtClustDB:   PRK13324
- BioCyc:   FTUL393115:FTF0112-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27985; Mature: 27985

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 133-133 BINDING 185-185

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLVMDMGNSHIHIGVFDGDRIVSQIRYATSSVDSTSDQMGVFLRQALRENSVDLGKIDG
CEEEEECCCCEEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
CGISSVVPHLNYSLGSAVIKYFNIKPFFISMDTTDLDMSAVEAHQVGADRIASCISAIAD
CCHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHC
HPNKDLLIIDLGTATTFDLVTKDKKYLSGSIMPGVKLSLNALCQGASQLSSVTIVKPEVA
CCCCCEEEEECCCCCEEHHHHCCHHHHCCCCCCCCCEEHHHHHCCHHHHCEEEEECCCEE
IGYDTKTNIRSGLYYGHLGALKELKRRSVEEFGSPVYTIATGGFAGLFKEEDIFNEISPD
ECCCCCCCHHCCEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHCCCCHHHHHHCCHH
LILRGIRIAFLENNKKGV
HHHHCEEEEEEECCCCCC
>Mature Secondary Structure
MLLVMDMGNSHIHIGVFDGDRIVSQIRYATSSVDSTSDQMGVFLRQALRENSVDLGKIDG
CEEEEECCCCEEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
CGISSVVPHLNYSLGSAVIKYFNIKPFFISMDTTDLDMSAVEAHQVGADRIASCISAIAD
CCHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHC
HPNKDLLIIDLGTATTFDLVTKDKKYLSGSIMPGVKLSLNALCQGASQLSSVTIVKPEVA
CCCCCEEEEECCCCCEEHHHHCCHHHHCCCCCCCCCEEHHHHHCCHHHHCEEEEECCCEE
IGYDTKTNIRSGLYYGHLGALKELKRRSVEEFGSPVYTIATGGFAGLFKEEDIFNEISPD
ECCCCCCCHHCCEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHCCCCHHHHHHCCHH
LILRGIRIAFLENNKKGV
HHHHCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA