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The map label for this gene is nuoC [H]

Identifier: 134301248

GI number: 134301248

Start: 116922

End: 117566

Strand: Direct

Name: nuoC [H]

Synonym: FTW_0108

Alternate gene names: 134301248

Gene position: 116922-117566 (Clockwise)

Preceding gene: 134301247

Following gene: 134301249

Centisome position: 6.16

GC content: 36.43

Gene sequence:

>645_bases
GTGAGTACTAAATTACAAGATCATTTTGATAAAATAACAAAGATTTTGAGTGGCTTTGGCGTTGAGGGCTGTATATCTTA
TGGCGAGATAACTTTTTCTATCAGGGATCAGCGTGATATTCATTTAATTTTAAAAAAACTTAAAAAAGAGTATCTTTTTG
AGCAGCTTACAGACGTAACAGCTGTTGATTATTTGACCTATGGTCAGTCAGACTGGCAGGTTGGTAAGGTTGTTTCACAA
ACAGGTTTTTCTAGAGGGCGTCAGCAAGATTTCAAAACCGCTGCTGTGGATAATAGATTTGAAATTATTTATCAGCTACT
AAGTATGGCAAATAATGTCAGAATTAGAGTTAAGTGTAAACTAAAAGATGCGCAGATCATTTTGGTTGATTCTGTCAGTG
ATTTATGGCCATCAGCTAACTGGACTGAGAGAGAAGTCTACGATATGTTTGGAATTTACTTTAATAATCATCCTGATTTA
AGAAGAGTGCTTACTGATTATGGTTTCGTTGGACACCCTTTGAGAAAAGATTTCCCGCAAACAGGCTATGTTGAGATGCG
TTATGATGAAAACCTTGGTCGAGTTGTGTATGAGCCGGTAGAGATTGATGATAGGGTTAATACACCAAGAGTGATTCGTA
ACTAA

Upstream 100 bases:

>100_bases
ATGTGCCAGGTTGTCCTCCTACTGCTGAGGCTTTAGTTTACGGCATTATACAACTGCAGAATAAAATTATTAGAAAAGAT
ACTATAGCGAGGAAGTGATC

Downstream 100 bases:

>100_bases
ATATAACTATGGGTTTATATAATGGCAGAGTATAAAAACTATACACTAAATTTTGGACCAGTTCATCCTGCAGCGCATGG
TGTTCTTAGGCTTATTTTAG

Product: NADH dehydrogenase I subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MSTKLQDHFDKITKILSGFGVEGCISYGEITFSIRDQRDIHLILKKLKKEYLFEQLTDVTAVDYLTYGQSDWQVGKVVSQ
TGFSRGRQQDFKTAAVDNRFEIIYQLLSMANNVRIRVKCKLKDAQIILVDSVSDLWPSANWTEREVYDMFGIYFNNHPDL
RRVLTDYGFVGHPLRKDFPQTGYVEMRYDENLGRVVYEPVEIDDRVNTPRVIRN

Sequences:

>Translated_214_residues
MSTKLQDHFDKITKILSGFGVEGCISYGEITFSIRDQRDIHLILKKLKKEYLFEQLTDVTAVDYLTYGQSDWQVGKVVSQ
TGFSRGRQQDFKTAAVDNRFEIIYQLLSMANNVRIRVKCKLKDAQIILVDSVSDLWPSANWTEREVYDMFGIYFNNHPDL
RRVLTDYGFVGHPLRKDFPQTGYVEMRYDENLGRVVYEPVEIDDRVNTPRVIRN
>Mature_213_residues
STKLQDHFDKITKILSGFGVEGCISYGEITFSIRDQRDIHLILKKLKKEYLFEQLTDVTAVDYLTYGQSDWQVGKVVSQT
GFSRGRQQDFKTAAVDNRFEIIYQLLSMANNVRIRVKCKLKDAQIILVDSVSDLWPSANWTEREVYDMFGIYFNNHPDLR
RVLTDYGFVGHPLRKDFPQTGYVEMRYDENLGRVVYEPVEIDDRVNTPRVIRN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=105, Percent_Identity=59.0476190476191, Blast_Score=137, Evalue=6e-33,
Organism=Escherichia coli, GI145693162, Length=80, Percent_Identity=43.75, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32563621, Length=117, Percent_Identity=53.8461538461538, Blast_Score=134, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71990788, Length=117, Percent_Identity=53.8461538461538, Blast_Score=133, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24656494, Length=105, Percent_Identity=56.1904761904762, Blast_Score=132, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 25005; Mature: 24874

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKLQDHFDKITKILSGFGVEGCISYGEITFSIRDQRDIHLILKKLKKEYLFEQLTDVT
CCCCHHHHHHHHHHHHHCCCHHHEEEECEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
AVDYLTYGQSDWQVGKVVSQTGFSRGRQQDFKTAAVDNRFEIIYQLLSMANNVRIRVKCK
HHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHCCCEEEEEEEE
LKDAQIILVDSVSDLWPSANWTEREVYDMFGIYFNNHPDLRRVLTDYGFVGHPLRKDFPQ
ECCCEEEEEECCHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHCCCC
TGYVEMRYDENLGRVVYEPVEIDDRVNTPRVIRN
CCEEEEEECCCCCCEEECCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
STKLQDHFDKITKILSGFGVEGCISYGEITFSIRDQRDIHLILKKLKKEYLFEQLTDVT
CCCHHHHHHHHHHHHHCCCHHHEEEECEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
AVDYLTYGQSDWQVGKVVSQTGFSRGRQQDFKTAAVDNRFEIIYQLLSMANNVRIRVKCK
HHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHCCCEEEEEEEE
LKDAQIILVDSVSDLWPSANWTEREVYDMFGIYFNNHPDLRRVLTDYGFVGHPLRKDFPQ
ECCCEEEEEECCHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHCCCC
TGYVEMRYDENLGRVVYEPVEIDDRVNTPRVIRN
CCEEEEEECCCCCCEEECCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA