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The map label for this gene is obgE [H]

Identifier: 134301217

GI number: 134301217

Start: 73754

End: 74758

Strand: Direct

Name: obgE [H]

Synonym: FTW_0066

Alternate gene names: 134301217

Gene position: 73754-74758 (Clockwise)

Preceding gene: 134301216

Following gene: 134301218

Centisome position: 3.88

GC content: 37.21

Gene sequence:

>1005_bases
ATGAGATTTGTAGATGAAGTAGTGATTAAGCTTCAAGCAGGAAAAGGTGGTAATGGTTGTGTGAGTTTCCGCCGTGAGAA
ATATGTTCCACGTGGAGGTCCTGATGGCGGTGATGGTGGTAATGGCGGTAGTATCTACCTAAAAGCAGATGAAAATGTAA
ACACCTTGATTGATTACCGTTATAAAAGAGAATACTATGCTGAGAATGGTCGCCCTGGAGAGGGGCGTAATTGTTATGGT
AAAGCTGGAGAAGATTTATATCTAGTTGTACCGGTTGGTACTAGTGTTTTTAATATTGATACAAATAAAAAAATTGGCGA
AGTACTACAGCATGGACAAACCTTTAAGCTAGTATCAGGTGGTAAAAGAGGTATTGGTAATACACACTTCAAAAGTAGTA
CAAATCAAGCACCGAGGAAGTTTACCTTAGGTGAAGAAGGTGAGTACAAAGAAGTTAGACTAGAACTTAATCTGTTAGCT
GATGTTGCTTTATTGGGCTTGCCTAATGCTGGTAAATCAACTCTTATTCGCTCAGTATCTGAAGCAACGCCTAAAGTTGC
TGATTATCCATTTACGACAATGTATCCTCACTTAGGGGTTGTCAAAGTCGGTGTAGATAGTTTTGTAATGGCAGATATTC
CAGGAGTTATTGAGGGTGCTGCTGAAGGTGCTGGTCTTGGACTTAGATTCTTAAAGCATCTAACTCGAGCTAGGTGTGTA
TTGCATGTTGTTGATATTTGTCCTTTTAATGAGTCAGATCCTGTTGAGAACTATTTTGCTGTAGAAAAAGAACTTGAGAA
ATATAGTCAAGAATTATTTGATAAACCAAGATTTTTAGTTATTAACAAAATTGATCTACTAGCTGATAAAGTTGAGCAAA
AATGTCAAGAGTTCGTTGAGCAAATAGGTTATCAAGGCAATTACTACACAATATCAGCAGCTATGAAAAAAGGAACAGAT
GAGTTGGCTAAAAAACTTAATGAGTTTTTACAAAAGCAACAGTAA

Upstream 100 bases:

>100_bases
TATTAATCCTTTTAGTGGCTTTTAAATAGTCGATGATAATTTGAGCTAGAACATATATAATGTATGATTAGCATTTTTGT
AAGTATAAGATTTTGATATT

Downstream 100 bases:

>100_bases
GTATAGATGAAGATAAAAAACCTGATATTTGGTTCACCAATTCCTAATGCAAAACAGCAAGAACAAAAAATAGGTTTATT
TGCCGGTTTTGCGATACTTT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MRFVDEVVIKLQAGKGGNGCVSFRREKYVPRGGPDGGDGGNGGSIYLKADENVNTLIDYRYKREYYAENGRPGEGRNCYG
KAGEDLYLVVPVGTSVFNIDTNKKIGEVLQHGQTFKLVSGGKRGIGNTHFKSSTNQAPRKFTLGEEGEYKEVRLELNLLA
DVALLGLPNAGKSTLIRSVSEATPKVADYPFTTMYPHLGVVKVGVDSFVMADIPGVIEGAAEGAGLGLRFLKHLTRARCV
LHVVDICPFNESDPVENYFAVEKELEKYSQELFDKPRFLVINKIDLLADKVEQKCQEFVEQIGYQGNYYTISAAMKKGTD
ELAKKLNEFLQKQQ

Sequences:

>Translated_334_residues
MRFVDEVVIKLQAGKGGNGCVSFRREKYVPRGGPDGGDGGNGGSIYLKADENVNTLIDYRYKREYYAENGRPGEGRNCYG
KAGEDLYLVVPVGTSVFNIDTNKKIGEVLQHGQTFKLVSGGKRGIGNTHFKSSTNQAPRKFTLGEEGEYKEVRLELNLLA
DVALLGLPNAGKSTLIRSVSEATPKVADYPFTTMYPHLGVVKVGVDSFVMADIPGVIEGAAEGAGLGLRFLKHLTRARCV
LHVVDICPFNESDPVENYFAVEKELEKYSQELFDKPRFLVINKIDLLADKVEQKCQEFVEQIGYQGNYYTISAAMKKGTD
ELAKKLNEFLQKQQ
>Mature_334_residues
MRFVDEVVIKLQAGKGGNGCVSFRREKYVPRGGPDGGDGGNGGSIYLKADENVNTLIDYRYKREYYAENGRPGEGRNCYG
KAGEDLYLVVPVGTSVFNIDTNKKIGEVLQHGQTFKLVSGGKRGIGNTHFKSSTNQAPRKFTLGEEGEYKEVRLELNLLA
DVALLGLPNAGKSTLIRSVSEATPKVADYPFTTMYPHLGVVKVGVDSFVMADIPGVIEGAAEGAGLGLRFLKHLTRARCV
LHVVDICPFNESDPVENYFAVEKELEKYSQELFDKPRFLVINKIDLLADKVEQKCQEFVEQIGYQGNYYTISAAMKKGTD
ELAKKLNEFLQKQQ

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=285, Percent_Identity=40, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI111955139, Length=251, Percent_Identity=38.2470119521912, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI111955063, Length=143, Percent_Identity=43.3566433566434, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1789574, Length=333, Percent_Identity=57.3573573573574, Blast_Score=345, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI17508313, Length=327, Percent_Identity=37.6146788990826, Blast_Score=157, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17552324, Length=335, Percent_Identity=31.3432835820896, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17509631, Length=158, Percent_Identity=32.2784810126582, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71981008, Length=117, Percent_Identity=34.1880341880342, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=168, Percent_Identity=37.5, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24585318, Length=270, Percent_Identity=37.7777777777778, Blast_Score=154, Evalue=7e-38,
Organism=Drosophila melanogaster, GI20129375, Length=315, Percent_Identity=37.1428571428571, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 36923; Mature: 36923

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVDEVVIKLQAGKGGNGCVSFRREKYVPRGGPDGGDGGNGGSIYLKADENVNTLIDYR
CCCHHEEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHH
YKREYYAENGRPGEGRNCYGKAGEDLYLVVPVGTSVFNIDTNKKIGEVLQHGQTFKLVSG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCCHHHHHHHHCCCEEEEECC
GKRGIGNTHFKSSTNQAPRKFTLGEEGEYKEVRLELNLLADVALLGLPNAGKSTLIRSVS
CCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHH
EATPKVADYPFTTMYPHLGVVKVGVDSFVMADIPGVIEGAAEGAGLGLRFLKHLTRARCV
HCCCCCCCCCCHHHCCCCCEEEECCCHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHH
LHVVDICPFNESDPVENYFAVEKELEKYSQELFDKPRFLVINKIDLLADKVEQKCQEFVE
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHH
QIGYQGNYYTISAAMKKGTDELAKKLNEFLQKQQ
HHCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRFVDEVVIKLQAGKGGNGCVSFRREKYVPRGGPDGGDGGNGGSIYLKADENVNTLIDYR
CCCHHEEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHH
YKREYYAENGRPGEGRNCYGKAGEDLYLVVPVGTSVFNIDTNKKIGEVLQHGQTFKLVSG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCCHHHHHHHHCCCEEEEECC
GKRGIGNTHFKSSTNQAPRKFTLGEEGEYKEVRLELNLLADVALLGLPNAGKSTLIRSVS
CCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEHHHHHHHHHHCCCCCCHHHHHHHHH
EATPKVADYPFTTMYPHLGVVKVGVDSFVMADIPGVIEGAAEGAGLGLRFLKHLTRARCV
HCCCCCCCCCCHHHCCCCCEEEECCCHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHH
LHVVDICPFNESDPVENYFAVEKELEKYSQELFDKPRFLVINKIDLLADKVEQKCQEFVE
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHH
QIGYQGNYYTISAAMKKGTDELAKKLNEFLQKQQ
HHCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA