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The map label for this gene is clpB [H]

Identifier: 134301181

GI number: 134301181

Start: 12455

End: 15034

Strand: Direct

Name: clpB [H]

Synonym: FTW_0017

Alternate gene names: 134301181

Gene position: 12455-15034 (Clockwise)

Preceding gene: 134301179

Following gene: 134301182

Centisome position: 0.66

GC content: 35.85

Gene sequence:

>2580_bases
ATGGATATAAATAAATTTACAATAAAACTACAAGAAGCTCTAGCTGAGGCTCAATCTTATGCTTTTCAACAAAAAGCAAC
TGAGTTTACATCAGCACATATACTAAAAGCTCTTTTGGAGCAAAATGATAGTGTTGCTATATCTATATTAAGCGTTTGTG
GTGTTAATATACAAAACTTTATAAAAGCTGTAAATGATATGGTTGATAGTGTTGCGGTATTATCTGGAGAAGGTAACCCT
CAAGTAACACCATCTAGAGATTTAATAGCTACATTACATAAAATGCAAGGGCTTGCTAATAAAAATGGTGATGAGTTTAT
CTCGAGTGAGGTTTTCTTATTAGCCTCTTTAGAAGACAAAAGTTTAACTGGACTGTATAACAAATTTGGTATTACAAAAG
AAAAATTAACAAAAGCAGTCAATGATTATCGCGGAGGGGAGAAAGTGAGTAGTCAAAATCAAGAAGATATGAAAGGTGCA
TTAGATAAATACACGGTAGATCTAACTGATCTAGCGAGAAAAGGAAAAATTGATCCAATAATCGGTAGAGATAGTGAGAT
CCGTAGAACTATTCAAGTATTACAAAGAAGAACTAAGAACAACCCTGTGCTTATAGGTGAGCCTGGTGTTGGTAAAACTG
CTATTGTTGAGGGCTTAGCTCAACGAATAGTTAATGATGAAGTACCAGAAGGTGTCAAAGGTAAAAAAGTACTATCATTA
GATATGGGTGCACTGCTAGCTGGTGCTAAATTTAGAGGAGATTTTGAAGAGCGTCTAAAATCTGTATTAAAAGAGCTATC
AAAACAAGAAGGTAATGTAATTCTCTTTATAGATGAATTACATACTATGGTAGGTGCTGGTAAAGCAGAAGGATCTATGG
ATGCTGGTAACATGCTTAAACCTGCTCTAGCTAGAGGAGAGCTAAAGTGTGTTGGTGCAACAACTTTAGATGAGTATCGT
GAGTATGTTGAAAAAGATCCGGCACTTGAGCGAAGATTCCAGAAAGTGCTAGTTGATGAACCTACTGTAGAAGATACTAT
CGCTATACTTAGAGGCCTAAAAGAAAGATATGAGCTACATCATGGTGTAAATATCACAGATTCAGCTATTGTAAGTGCAG
CAACTTTGTCACATAGGTATATCACAGATAGACAGCTACCTGATAAAGCTATAGATCTAGTAGATGAAGCAGCAAGCCAA
ATTCGTATGGAAATAGACTCTAAACCTGAAAAAATGGAAAGCTTATATCGTAGAATCATCCAGCTGAAAATGCAACGCGA
ACAGCTAAAGAAAGAGAAAGATGATGCTACTAAAAAACGTTTAGAGATACTTGAGCAAGAAATAAAAGGGCTAGATTCCG
AGTATAAAGGACTAGAAGAGCTTTGGAAAGCTGAAAAGCTTAAGATGCAAGGTACAAGTAAACTAAAAGAAGAGCTTGAG
AAAGCCAAGTTTGAACTTGAAAAGTACCAAAGAGTGGGTGATTTGAGCAAAATGGCAGAATTACAATACGGTAAAATACC
TGAGCTAGAAGCACAAATTAAACAAATAGAAGAAACTGAAGCAGAACCTTCTGAAAACAAATTAGTAAGAACATCTGTTA
CAGAAAATGAGATTGCTGATGTAGTTTCAAAAGCTACTGGAATACCTGTGTCTAAGATGATGGAAGGCGAAAAAGACAAG
CTTCTAAATATGGAAAGTTTCTTACATAAAAGAGTAATCGGACAAGATCAAGCTATAAAAGCAGTATCAAATGCTGTAAG
AAGATCTCGTTCTGGATTATCAGATCCAAATAGACCTATAGGCTCATTCATGTTCTTAGGTCCAACTGGTGTCGGTAAAA
CTGAGCTTACAAAAGCTTTAGCAGAGTTTTTGTTTGATGATGAAGATGCCATGCTTAGAGTAGATATGTCTGAGTTTATG
GAGAAACATTCTGTAGCTAGACTAATAGGCGCTCCTCCTGGATACGTAGGTTATGAACAAGGCGGCTATCTAACTGAACA
TGTTAGAAGAAAACCTTATTCTGTAATCTTACTTGATGAGATTGAAAAAGCTCATGCTGATATATTTAACATCTTACTAC
AAGTGCTTGACGATGGTCGCCTAACAGATGGGCAAGGCAGAACAGTAGACTTTAAAAATACTGTAATAGTTATGACTTCT
AACCTTGGTTCACATCGAATCCAAGAAATGCAAGGTCAGGATTATGAAACAGTAAAATCTGCTGTAATGGAAATGGTACT
TAGCCACTTTAGACCTGAATTTGTAAATAGAGTTGATGATGCAATTGTCTTTGAACCTCTAAACAAAGAGATGATAACTG
AAATAGCTAAAATACAAATCAAACGCTTAGAAAAACGTCTAGCAGATCTAAGTATAGGATTAGAAGTCACAACTGAAGCT
ATGGATAAACTAGCTGATGCTGGCTTTGATCCTGTGTTTGGTGCTAGACCGCTTAAGCGCGCTATTCAAAACAACTTAGA
AAACCCTCTGGCTCTAAAACTTCTAGATGGTGAGTTTAAAGCTGAAGATAAAATAGTTGTCGATATTGACGCTAATAACA
ATATTACATTCTCTAAATAA

Upstream 100 bases:

>100_bases
ACTTATACATATTTTTTTTCTAATAAGCATAATTTTATTACTTGAAAAACAGCAAAGTATCCTTAAGTATATAACAGATG
CTATTTCTTAGGGGAAAATA

Downstream 100 bases:

>100_bases
AATCGGTTTAATCAATTATCTAAATTATAAAATTGTTAAGAATGTTGCTTTAATAGCTTAAGAGCCTCGAGTATTTAGAT
AAGCTCAGTCAAATTATTCT

Product: AAA ATPase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 859; Mature: 859

Protein sequence:

>859_residues
MDINKFTIKLQEALAEAQSYAFQQKATEFTSAHILKALLEQNDSVAISILSVCGVNIQNFIKAVNDMVDSVAVLSGEGNP
QVTPSRDLIATLHKMQGLANKNGDEFISSEVFLLASLEDKSLTGLYNKFGITKEKLTKAVNDYRGGEKVSSQNQEDMKGA
LDKYTVDLTDLARKGKIDPIIGRDSEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNDEVPEGVKGKKVLSL
DMGALLAGAKFRGDFEERLKSVLKELSKQEGNVILFIDELHTMVGAGKAEGSMDAGNMLKPALARGELKCVGATTLDEYR
EYVEKDPALERRFQKVLVDEPTVEDTIAILRGLKERYELHHGVNITDSAIVSAATLSHRYITDRQLPDKAIDLVDEAASQ
IRMEIDSKPEKMESLYRRIIQLKMQREQLKKEKDDATKKRLEILEQEIKGLDSEYKGLEELWKAEKLKMQGTSKLKEELE
KAKFELEKYQRVGDLSKMAELQYGKIPELEAQIKQIEETEAEPSENKLVRTSVTENEIADVVSKATGIPVSKMMEGEKDK
LLNMESFLHKRVIGQDQAIKAVSNAVRRSRSGLSDPNRPIGSFMFLGPTGVGKTELTKALAEFLFDDEDAMLRVDMSEFM
EKHSVARLIGAPPGYVGYEQGGYLTEHVRRKPYSVILLDEIEKAHADIFNILLQVLDDGRLTDGQGRTVDFKNTVIVMTS
NLGSHRIQEMQGQDYETVKSAVMEMVLSHFRPEFVNRVDDAIVFEPLNKEMITEIAKIQIKRLEKRLADLSIGLEVTTEA
MDKLADAGFDPVFGARPLKRAIQNNLENPLALKLLDGEFKAEDKIVVDIDANNNITFSK

Sequences:

>Translated_859_residues
MDINKFTIKLQEALAEAQSYAFQQKATEFTSAHILKALLEQNDSVAISILSVCGVNIQNFIKAVNDMVDSVAVLSGEGNP
QVTPSRDLIATLHKMQGLANKNGDEFISSEVFLLASLEDKSLTGLYNKFGITKEKLTKAVNDYRGGEKVSSQNQEDMKGA
LDKYTVDLTDLARKGKIDPIIGRDSEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNDEVPEGVKGKKVLSL
DMGALLAGAKFRGDFEERLKSVLKELSKQEGNVILFIDELHTMVGAGKAEGSMDAGNMLKPALARGELKCVGATTLDEYR
EYVEKDPALERRFQKVLVDEPTVEDTIAILRGLKERYELHHGVNITDSAIVSAATLSHRYITDRQLPDKAIDLVDEAASQ
IRMEIDSKPEKMESLYRRIIQLKMQREQLKKEKDDATKKRLEILEQEIKGLDSEYKGLEELWKAEKLKMQGTSKLKEELE
KAKFELEKYQRVGDLSKMAELQYGKIPELEAQIKQIEETEAEPSENKLVRTSVTENEIADVVSKATGIPVSKMMEGEKDK
LLNMESFLHKRVIGQDQAIKAVSNAVRRSRSGLSDPNRPIGSFMFLGPTGVGKTELTKALAEFLFDDEDAMLRVDMSEFM
EKHSVARLIGAPPGYVGYEQGGYLTEHVRRKPYSVILLDEIEKAHADIFNILLQVLDDGRLTDGQGRTVDFKNTVIVMTS
NLGSHRIQEMQGQDYETVKSAVMEMVLSHFRPEFVNRVDDAIVFEPLNKEMITEIAKIQIKRLEKRLADLSIGLEVTTEA
MDKLADAGFDPVFGARPLKRAIQNNLENPLALKLLDGEFKAEDKIVVDIDANNNITFSK
>Mature_859_residues
MDINKFTIKLQEALAEAQSYAFQQKATEFTSAHILKALLEQNDSVAISILSVCGVNIQNFIKAVNDMVDSVAVLSGEGNP
QVTPSRDLIATLHKMQGLANKNGDEFISSEVFLLASLEDKSLTGLYNKFGITKEKLTKAVNDYRGGEKVSSQNQEDMKGA
LDKYTVDLTDLARKGKIDPIIGRDSEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNDEVPEGVKGKKVLSL
DMGALLAGAKFRGDFEERLKSVLKELSKQEGNVILFIDELHTMVGAGKAEGSMDAGNMLKPALARGELKCVGATTLDEYR
EYVEKDPALERRFQKVLVDEPTVEDTIAILRGLKERYELHHGVNITDSAIVSAATLSHRYITDRQLPDKAIDLVDEAASQ
IRMEIDSKPEKMESLYRRIIQLKMQREQLKKEKDDATKKRLEILEQEIKGLDSEYKGLEELWKAEKLKMQGTSKLKEELE
KAKFELEKYQRVGDLSKMAELQYGKIPELEAQIKQIEETEAEPSENKLVRTSVTENEIADVVSKATGIPVSKMMEGEKDK
LLNMESFLHKRVIGQDQAIKAVSNAVRRSRSGLSDPNRPIGSFMFLGPTGVGKTELTKALAEFLFDDEDAMLRVDMSEFM
EKHSVARLIGAPPGYVGYEQGGYLTEHVRRKPYSVILLDEIEKAHADIFNILLQVLDDGRLTDGQGRTVDFKNTVIVMTS
NLGSHRIQEMQGQDYETVKSAVMEMVLSHFRPEFVNRVDDAIVFEPLNKEMITEIAKIQIKRLEKRLADLSIGLEVTTEA
MDKLADAGFDPVFGARPLKRAIQNNLENPLALKLLDGEFKAEDKIVVDIDANNNITFSK

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=299, Percent_Identity=36.4548494983278, Blast_Score=195, Evalue=2e-49,
Organism=Escherichia coli, GI1788943, Length=841, Percent_Identity=63.4958382877527, Blast_Score=1095, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=382, Percent_Identity=42.4083769633508, Blast_Score=282, Evalue=8e-77,
Organism=Saccharomyces cerevisiae, GI6320464, Length=693, Percent_Identity=54.2568542568543, Blast_Score=761, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=862, Percent_Identity=42.92343387471, Blast_Score=682, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 96004; Mature: 96004

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINKFTIKLQEALAEAQSYAFQQKATEFTSAHILKALLEQNDSVAISILSVCGVNIQNF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHH
IKAVNDMVDSVAVLSGEGNPQVTPSRDLIATLHKMQGLANKNGDEFISSEVFLLASLEDK
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCEEEEEECCCC
SLTGLYNKFGITKEKLTKAVNDYRGGEKVSSQNQEDMKGALDKYTVDLTDLARKGKIDPI
HHHHHHHHHCCCHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHEECHHHHHHCCCCCCC
IGRDSEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNDEVPEGVKGKKVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
DMGALLAGAKFRGDFEERLKSVLKELSKQEGNVILFIDELHTMVGAGKAEGSMDAGNMLK
CHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCCHHH
PALARGELKCVGATTLDEYREYVEKDPALERRFQKVLVDEPTVEDTIAILRGLKERYELH
HHHHCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HGVNITDSAIVSAATLSHRYITDRQLPDKAIDLVDEAASQIRMEIDSKPEKMESLYRRII
CCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QLKMQREQLKKEKDDATKKRLEILEQEIKGLDSEYKGLEELWKAEKLKMQGTSKLKEELE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KAKFELEKYQRVGDLSKMAELQYGKIPELEAQIKQIEETEAEPSENKLVRTSVTENEIAD
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHH
VVSKATGIPVSKMMEGEKDKLLNMESFLHKRVIGQDQAIKAVSNAVRRSRSGLSDPNRPI
HHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCC
GSFMFLGPTGVGKTELTKALAEFLFDDEDAMLRVDMSEFMEKHSVARLIGAPPGYVGYEQ
CCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCC
GGYLTEHVRRKPYSVILLDEIEKAHADIFNILLQVLDDGRLTDGQGRTVDFKNTVIVMTS
CCHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEEC
NLGSHRIQEMQGQDYETVKSAVMEMVLSHFRPEFVNRVDDAIVFEPLNKEMITEIAKIQI
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHEECCCCHHHHHHHHHHHH
KRLEKRLADLSIGLEVTTEAMDKLADAGFDPVFGARPLKRAIQNNLENPLALKLLDGEFK
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCC
AEDKIVVDIDANNNITFSK
CCCCEEEEEECCCCEECCC
>Mature Secondary Structure
MDINKFTIKLQEALAEAQSYAFQQKATEFTSAHILKALLEQNDSVAISILSVCGVNIQNF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHH
IKAVNDMVDSVAVLSGEGNPQVTPSRDLIATLHKMQGLANKNGDEFISSEVFLLASLEDK
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCEEEEEECCCC
SLTGLYNKFGITKEKLTKAVNDYRGGEKVSSQNQEDMKGALDKYTVDLTDLARKGKIDPI
HHHHHHHHHCCCHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHHHEECHHHHHHCCCCCCC
IGRDSEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNDEVPEGVKGKKVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
DMGALLAGAKFRGDFEERLKSVLKELSKQEGNVILFIDELHTMVGAGKAEGSMDAGNMLK
CHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCCHHH
PALARGELKCVGATTLDEYREYVEKDPALERRFQKVLVDEPTVEDTIAILRGLKERYELH
HHHHCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HGVNITDSAIVSAATLSHRYITDRQLPDKAIDLVDEAASQIRMEIDSKPEKMESLYRRII
CCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QLKMQREQLKKEKDDATKKRLEILEQEIKGLDSEYKGLEELWKAEKLKMQGTSKLKEELE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KAKFELEKYQRVGDLSKMAELQYGKIPELEAQIKQIEETEAEPSENKLVRTSVTENEIAD
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHH
VVSKATGIPVSKMMEGEKDKLLNMESFLHKRVIGQDQAIKAVSNAVRRSRSGLSDPNRPI
HHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCC
GSFMFLGPTGVGKTELTKALAEFLFDDEDAMLRVDMSEFMEKHSVARLIGAPPGYVGYEQ
CCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCC
GGYLTEHVRRKPYSVILLDEIEKAHADIFNILLQVLDDGRLTDGQGRTVDFKNTVIVMTS
CCHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEEC
NLGSHRIQEMQGQDYETVKSAVMEMVLSHFRPEFVNRVDDAIVFEPLNKEMITEIAKIQI
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHEECCCCHHHHHHHHHHHH
KRLEKRLADLSIGLEVTTEAMDKLADAGFDPVFGARPLKRAIQNNLENPLALKLLDGEFK
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCC
AEDKIVVDIDANNNITFSK
CCCCEEEEEECCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]