| Definition | Desulfotomaculum reducens MI-1 chromosome, complete genome. |
|---|---|
| Accession | NC_009253 |
| Length | 3,608,104 |
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The map label for this gene is comEC [H]
Identifier: 134300349
GI number: 134300349
Start: 2729426
End: 2731810
Strand: Reverse
Name: comEC [H]
Synonym: Dred_2510
Alternate gene names: 134300349
Gene position: 2731810-2729426 (Counterclockwise)
Preceding gene: 134300350
Following gene: 134300346
Centisome position: 75.71
GC content: 44.86
Gene sequence:
>2385_bases ATGCAGCGCCCCCTGGTTTTTATGATACTGGCCTTTATGCTGGGTATTATGGTAACCTCTGTCCTTAAAGTTAATATACT CGTTGCGATGGGAGCAGCGGTTTTCACCTGCATAGTTGCAGGAATCGGCATCATCAGGACCTGGCGTTATAACACTTGGG TCCTTTTTTGTGCTTGTATCTGTCTTGGAATGGCCCTAACAACTATCAAGCTGTCCGTGGTGGCCACACCGCTGATGGAT TTTAAGGGAACTAATATTCAAGCAACCGGAATTGTTATTGATCAACCGGACCGCAGACCCGAAGCAACTTTCTACAAATT AAAAGTTCAGCAGGCTAAGTATGGGGGCAAGATAAAAAAGGTTTCAGGGATTCTGCGGGTCAAGGTGCCGGAAAAAACCA AGAGATATCAATACGGAGATATTCTGAGGTTAACAGGCTATGTGGTGGTGCCGGAACCTCCAGGTAACCCTGGGGCCTTC GATTACCGAACTTGGCTAAATCGACAGGGTATTGCTGCCAACATGGTTGTAAAGAAATCCGAAGATATCAAAGTCCTCCG CAGGGGTGAGGGCAGCTTTATTTTTCGTATTGCCTTTGCTTTACGAAATCACCTGGAAAGTATTTATGATAAAACCCTGT CTAAAGAGAAAGCTGTCATACTAAAGGGCTTGCTCTTTGGTACCCGTGGGGAAATACCCCAGGATGTACAATTAGCCTTT AACCAGACTGGGCTGGTACACATTCTCAGTGTCTCAGGTTATCATGTTGGCTTGGTGGCTGCTATGCTGTTGCAAGTGCT ACGTTTGTTAAAAGTACCTGCTCGCTTTACCGCCCCGGTGACCATTCCTTTACTAATTTTTTACGCCATAATGACAGGGC TGGGACCCGCGGTTTTACGTGCCACCCTGATGGCGGTTTTACTTTTACTGGCCCGCCACCTGGGACGACAGAATGATTGG CCTACAACGCTGGCTACGGCTGCCGGAATCATTTTGGCCATTAATCCACTGGATTTATATGATATTGGATTTCAACTCTC CTTTGTGGCAACCTGGGGTCTGCTTTATCTAACCCCTGTTTTAAACAACCTTTTTCATCAAATACCTAAATCCATTGTTT TATTAATCACAGTGCCACTGGCGGCTCAACTGGCAACCCTTCCTCTGGTGACCCTGTACTTTAACCTTGTTTCACAGGTT TCCATCCTGGCCAATTTGCTGACAGTTCACCTGGTGGGTCTGATTATGTTATTTGGTGGACTGGATTTACTTATCGGTAC GATCTACTTACCTCTGACCTCTCTTTTTAACAGTGGTATTAGTTCACTCATTGATTTATTTATTGGATTAGTACAATTTT GCAACTCTTTGCCCAGTGCCTCCTTTTATATTCCTACCCCACCCCTCTGGCTGGTTTTCCTATACTACGTTTTACTGATA TTCACTTTTTATTTATTCCAGTTTCCTGAAAAAAGAGAAAAAGTAGTAGGTTCTCATCAGCAGATTGAGAAATACAAAAC CCTTGTTCTGGTAGCACTTTTAATAATGACCCTTTGGCTGGTAAAACCTACCCATGGTTTGTTGGAAGTTCATTTTATAG ATGTAGGTCAGGGGGACAGTACCTTAATCATTACCCCCGAAAAACGAATTGTGCTGGTTGACACAGGGGGCTGGCAGAAT GAACTTCTTTCTGGCAGGGGAGCCGGAGAGTATGTAATCGTACCCTACTTACATAGATTAGGCATCAATCAAGTGGATGT GTTAGTGTTAACACACCCCCATGCAGATCATGTTGGCGGTGCTAGAACCCTTATCCAGACCATGTCAGTGGGAATGGTGA TGGTTTCGCCCTACGGGCTGCAGCCGGCAGATCATATCGATGAAGGCTATACTGAATTACTGCAAGAGATTGGAAAACTG GGGATACCCCTTTGTTCCGCCAGAGCAGGGGATGAGCTAAGGTTGGACTCTGAGTTGTTAATGTCATGTCTAGGCCCGGA AGATAAATTTATTGGCACCCGCTCCGATGCCAATAACAATAGTTTAATATTTTTACTGAAATACCATGGGCGTACGGTTT TACTAACCGGAGATATAGAGGCCGAGGCGGAAAAGAACCTGGTGGAGAACATCGAGATAACCAATATAGAAATATTGAAA GTTCCGCACCATGGCAGTGGTTTTTTTGACCCTGATTTCTTTCAGAGGGTGAGTCCTAAAGCTGCGATTATTTCGGTGGG CAAGGGCAATCGCTTTCATCACCCGTCTGTTAAAACCCTGGAGGCATTAGAAGAAGTAAATAGCAAAATCTACCGCACAG ATCGACAAGGGGCCATTATCTTAAGCACCGATGGATCAAAATGGCTGGTTCAAACGGGGAAATAA
Upstream 100 bases:
>100_bases GGCTGTTGAACGTTATGGAGGGATACCTCCCTATGAGGAAACTACTCGATATATACAGAAAGTAATTCGTTACCAGCAAA AGTATACTGGGGTTTAATAT
Downstream 100 bases:
>100_bases AATTAATACCGACCAAAGATGGCTTTCATGACATCATCAAAGGGCATAGTGCCTACCTGTTCCATTATTTTCTCCAATTC TGTTTTTCTTTTTAAGGAAC
Product: DNA internalization-related competence protein ComEC/Rec2
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 794; Mature: 794
Protein sequence:
>794_residues MQRPLVFMILAFMLGIMVTSVLKVNILVAMGAAVFTCIVAGIGIIRTWRYNTWVLFCACICLGMALTTIKLSVVATPLMD FKGTNIQATGIVIDQPDRRPEATFYKLKVQQAKYGGKIKKVSGILRVKVPEKTKRYQYGDILRLTGYVVVPEPPGNPGAF DYRTWLNRQGIAANMVVKKSEDIKVLRRGEGSFIFRIAFALRNHLESIYDKTLSKEKAVILKGLLFGTRGEIPQDVQLAF NQTGLVHILSVSGYHVGLVAAMLLQVLRLLKVPARFTAPVTIPLLIFYAIMTGLGPAVLRATLMAVLLLLARHLGRQNDW PTTLATAAGIILAINPLDLYDIGFQLSFVATWGLLYLTPVLNNLFHQIPKSIVLLITVPLAAQLATLPLVTLYFNLVSQV SILANLLTVHLVGLIMLFGGLDLLIGTIYLPLTSLFNSGISSLIDLFIGLVQFCNSLPSASFYIPTPPLWLVFLYYVLLI FTFYLFQFPEKREKVVGSHQQIEKYKTLVLVALLIMTLWLVKPTHGLLEVHFIDVGQGDSTLIITPEKRIVLVDTGGWQN ELLSGRGAGEYVIVPYLHRLGINQVDVLVLTHPHADHVGGARTLIQTMSVGMVMVSPYGLQPADHIDEGYTELLQEIGKL GIPLCSARAGDELRLDSELLMSCLGPEDKFIGTRSDANNNSLIFLLKYHGRTVLLTGDIEAEAEKNLVENIEITNIEILK VPHHGSGFFDPDFFQRVSPKAAIISVGKGNRFHHPSVKTLEALEEVNSKIYRTDRQGAIILSTDGSKWLVQTGK
Sequences:
>Translated_794_residues MQRPLVFMILAFMLGIMVTSVLKVNILVAMGAAVFTCIVAGIGIIRTWRYNTWVLFCACICLGMALTTIKLSVVATPLMD FKGTNIQATGIVIDQPDRRPEATFYKLKVQQAKYGGKIKKVSGILRVKVPEKTKRYQYGDILRLTGYVVVPEPPGNPGAF DYRTWLNRQGIAANMVVKKSEDIKVLRRGEGSFIFRIAFALRNHLESIYDKTLSKEKAVILKGLLFGTRGEIPQDVQLAF NQTGLVHILSVSGYHVGLVAAMLLQVLRLLKVPARFTAPVTIPLLIFYAIMTGLGPAVLRATLMAVLLLLARHLGRQNDW PTTLATAAGIILAINPLDLYDIGFQLSFVATWGLLYLTPVLNNLFHQIPKSIVLLITVPLAAQLATLPLVTLYFNLVSQV SILANLLTVHLVGLIMLFGGLDLLIGTIYLPLTSLFNSGISSLIDLFIGLVQFCNSLPSASFYIPTPPLWLVFLYYVLLI FTFYLFQFPEKREKVVGSHQQIEKYKTLVLVALLIMTLWLVKPTHGLLEVHFIDVGQGDSTLIITPEKRIVLVDTGGWQN ELLSGRGAGEYVIVPYLHRLGINQVDVLVLTHPHADHVGGARTLIQTMSVGMVMVSPYGLQPADHIDEGYTELLQEIGKL GIPLCSARAGDELRLDSELLMSCLGPEDKFIGTRSDANNNSLIFLLKYHGRTVLLTGDIEAEAEKNLVENIEITNIEILK VPHHGSGFFDPDFFQRVSPKAAIISVGKGNRFHHPSVKTLEALEEVNSKIYRTDRQGAIILSTDGSKWLVQTGK >Mature_794_residues MQRPLVFMILAFMLGIMVTSVLKVNILVAMGAAVFTCIVAGIGIIRTWRYNTWVLFCACICLGMALTTIKLSVVATPLMD FKGTNIQATGIVIDQPDRRPEATFYKLKVQQAKYGGKIKKVSGILRVKVPEKTKRYQYGDILRLTGYVVVPEPPGNPGAF DYRTWLNRQGIAANMVVKKSEDIKVLRRGEGSFIFRIAFALRNHLESIYDKTLSKEKAVILKGLLFGTRGEIPQDVQLAF NQTGLVHILSVSGYHVGLVAAMLLQVLRLLKVPARFTAPVTIPLLIFYAIMTGLGPAVLRATLMAVLLLLARHLGRQNDW PTTLATAAGIILAINPLDLYDIGFQLSFVATWGLLYLTPVLNNLFHQIPKSIVLLITVPLAAQLATLPLVTLYFNLVSQV SILANLLTVHLVGLIMLFGGLDLLIGTIYLPLTSLFNSGISSLIDLFIGLVQFCNSLPSASFYIPTPPLWLVFLYYVLLI FTFYLFQFPEKREKVVGSHQQIEKYKTLVLVALLIMTLWLVKPTHGLLEVHFIDVGQGDSTLIITPEKRIVLVDTGGWQN ELLSGRGAGEYVIVPYLHRLGINQVDVLVLTHPHADHVGGARTLIQTMSVGMVMVSPYGLQPADHIDEGYTELLQEIGKL GIPLCSARAGDELRLDSELLMSCLGPEDKFIGTRSDANNNSLIFLLKYHGRTVLLTGDIEAEAEKNLVENIEITNIEILK VPHHGSGFFDPDFFQRVSPKAAIISVGKGNRFHHPSVKTLEALEEVNSKIYRTDRQGAIILSTDGSKWLVQTGK
Specific function: The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding [H]
COG id: COG0658
COG function: function code R; Predicted membrane metal-binding protein
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: To H.influenzae REC2, N.gonorrhoeae ComA and E.coli YcaI [H]
Homologues:
Organism=Escherichia coli, GI87081801, Length=601, Percent_Identity=25.4575707154742, Blast_Score=132, Evalue=7e-32,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001279 - InterPro: IPR004477 - InterPro: IPR004797 [H]
Pfam domain/function: PF03772 Competence; PF00753 Lactamase_B [H]
EC number: NA
Molecular weight: Translated: 87768; Mature: 87768
Theoretical pI: Translated: 9.35; Mature: 9.35
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQRPLVFMILAFMLGIMVTSVLKVNILVAMGAAVFTCIVAGIGIIRTWRYNTWVLFCACI CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHH CLGMALTTIKLSVVATPLMDFKGTNIQATGIVIDQPDRRPEATFYKLKVQQAKYGGKIKK HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCEEEEEEEEHHHCCCCEEE VSGILRVKVPEKTKRYQYGDILRLTGYVVVPEPPGNPGAFDYRTWLNRQGIAANMVVKKS ECCEEEEECCCHHCCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHCCCCCEEEEEEECC EDIKVLRRGEGSFIFRIAFALRNHLESIYDKTLSKEKAVILKGLLFGTRGEIPQDVQLAF CCHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHC NQTGLVHILSVSGYHVGLVAAMLLQVLRLLKVPARFTAPVTIPLLIFYAIMTGLGPAVLR CCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH ATLMAVLLLLARHLGRQNDWPTTLATAAGIILAINPLDLYDIGFQLSFVATWGLLYLTPV HHHHHHHHHHHHHCCCCCCCCHHHHHHCCEEEEECCCCEECCCEEEHHHHHHHHHHHHHH LNNLFHQIPKSIVLLITVPLAAQLATLPLVTLYFNLVSQVSILANLLTVHLVGLIMLFGG HHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC LDLLIGTIYLPLTSLFNSGISSLIDLFIGLVQFCNSLPSASFYIPTPPLWLVFLYYVLLI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHH FTFYLFQFPEKREKVVGSHQQIEKYKTLVLVALLIMTLWLVKPTHGLLEVHFIDVGQGDS HHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCC TLIITPEKRIVLVDTGGWQNELLSGRGAGEYVIVPYLHRLGINQVDVLVLTHPHADHVGG EEEECCCCEEEEEECCCCHHHHHCCCCCCCEEEHHHHHHCCCCCEEEEEEECCCCCCCCH ARTLIQTMSVGMVMVSPYGLQPADHIDEGYTELLQEIGKLGIPLCSARAGDELRLDSELL HHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCHHHH MSCLGPEDKFIGTRSDANNNSLIFLLKYHGRTVLLTGDIEAEAEKNLVENIEITNIEILK HHHHCCCHHEEECCCCCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHHCCEEEEEEEEE VPHHGSGFFDPDFFQRVSPKAAIISVGKGNRFHHPSVKTLEALEEVNSKIYRTDRQGAII ECCCCCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHEECCCCCEEE LSTDGSKWLVQTGK EECCCCEEEEECCC >Mature Secondary Structure MQRPLVFMILAFMLGIMVTSVLKVNILVAMGAAVFTCIVAGIGIIRTWRYNTWVLFCACI CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHH CLGMALTTIKLSVVATPLMDFKGTNIQATGIVIDQPDRRPEATFYKLKVQQAKYGGKIKK HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCEEEEEEEEHHHCCCCEEE VSGILRVKVPEKTKRYQYGDILRLTGYVVVPEPPGNPGAFDYRTWLNRQGIAANMVVKKS ECCEEEEECCCHHCCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHCCCCCEEEEEEECC EDIKVLRRGEGSFIFRIAFALRNHLESIYDKTLSKEKAVILKGLLFGTRGEIPQDVQLAF CCHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHC NQTGLVHILSVSGYHVGLVAAMLLQVLRLLKVPARFTAPVTIPLLIFYAIMTGLGPAVLR CCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH ATLMAVLLLLARHLGRQNDWPTTLATAAGIILAINPLDLYDIGFQLSFVATWGLLYLTPV HHHHHHHHHHHHHCCCCCCCCHHHHHHCCEEEEECCCCEECCCEEEHHHHHHHHHHHHHH LNNLFHQIPKSIVLLITVPLAAQLATLPLVTLYFNLVSQVSILANLLTVHLVGLIMLFGG HHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC LDLLIGTIYLPLTSLFNSGISSLIDLFIGLVQFCNSLPSASFYIPTPPLWLVFLYYVLLI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHH FTFYLFQFPEKREKVVGSHQQIEKYKTLVLVALLIMTLWLVKPTHGLLEVHFIDVGQGDS HHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCC TLIITPEKRIVLVDTGGWQNELLSGRGAGEYVIVPYLHRLGINQVDVLVLTHPHADHVGG EEEECCCCEEEEEECCCCHHHHHCCCCCCCEEEHHHHHHCCCCCEEEEEEECCCCCCCCH ARTLIQTMSVGMVMVSPYGLQPADHIDEGYTELLQEIGKLGIPLCSARAGDELRLDSELL HHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCHHHH MSCLGPEDKFIGTRSDANNNSLIFLLKYHGRTVLLTGDIEAEAEKNLVENIEITNIEILK HHHHCCCHHEEECCCCCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHHCCEEEEEEEEE VPHHGSGFFDPDFFQRVSPKAAIISVGKGNRFHHPSVKTLEALEEVNSKIYRTDRQGAII ECCCCCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHEECCCCCEEE LSTDGSKWLVQTGK EECCCCEEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7968523; 8969508; 9384377 [H]