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The map label for this gene is cheB [H]

Identifier: 134300278

GI number: 134300278

Start: 2654850

End: 2655959

Strand: Reverse

Name: cheB [H]

Synonym: Dred_2439

Alternate gene names: 134300278

Gene position: 2655959-2654850 (Counterclockwise)

Preceding gene: 134300279

Following gene: 134300277

Centisome position: 73.61

GC content: 56.31

Gene sequence:

>1110_bases
ATGCTGCCGGTTAAAGTCCTGGTGGTGGACGATTCCTCCCTGATGAGGCGGCTGATTAGCCGCCTATTGGAGGAAGACAA
AGGAATAAAAGTCATTGGCACCGCTGCGGATGGACTGGAGGCCCTACAACAAATTAAGGCCCTGCGGCCCGATGTGGTAA
CCATGGATGTGGAGATGCCCAGGTTGGACGGTATTGCCACCCTGCGCCGCTTGATGGTGGATTTTCCTACACCAGCGGTG
ATGCTCAGTGCCCATACCCATGAGGGTGCCCGGGCCACCATGGATGCCCTGTCCGCCGGGGCAGTAGATTTTGTGGCAAA
ACCCACTTCCTCCGCTGAATTACCAAGGATGGTGGAGGATCTCAAGACCAAAGTAAAGGTAGCGGCCAGGGTTTCCCTGC
GCAGGGTGCGAACCACCCTAACACCGCCGCCGGCACCGCTGGCTCGGCCTAAGCCAGCCACAACAGCCGCCCCTGGGTCA
GCTAAAGCGAAGCCCCAGACCCAGGTTCGAAGGCAGCCCTATTGCGGCAAAATTGATCTAGTGGTCATTGGCTGCTCCAC
CGGTGGCCCCGCAGCCCTGCAGCAAATCATTCCCTACCTGCCTGCCAATTTACCCGCCGGGGTTGTGGTGGTTCAACATA
TTCCAGTGGGTTTTTCCAAATCCATGGCAGAGCATTTGGATAAGAAAAGTGCCATCTCGGTACGTCATGCCGCAGAGGGT
GATGCAATAAAAGCAGGCCAGGTACTGGTTGCCCCGGCGGGCTACGACTTAAACTTTAAGGCCAAAGGCAACGGCTCCAC
CGTTGCCCTGAGTAATCAAGGGGCTCCTTTGGCTCCCGGGGGTTTCCGCCCTTCGGTGGATTGGGTGATGAAATCTGCCG
CCGAAGTCTATGGTTGCCGAACCCTAGCCGTACTATTAACTGGGATGGGACGAGACGGTGCCAGAGGGATGCTGGCCATC
AAAGAACAGGGTGGCCCTACCATCGCTGAGCACGAAAGTACCTGTGTGGTTTATGGCATGCCCAAGGCAGCCTACGATAT
TGGGGCTGCGGGTAAAATGGTACCCTTACCACAGATTGCCCAGGAAATCCAAGCTTTTTTTGATGTTTAA

Upstream 100 bases:

>100_bases
CAGGGTCTCTCCGGTGCCTGCATCCTAGGTGATGGCAAAGTGGCCCTCATTGTGGATGTGAGAGGTCTGGTAAAGGATCT
CGGGGCTGAGGAGGTAGCCT

Downstream 100 bases:

>100_bases
TATAAAGTTAAGGTCTTGAACTGCCGAATACAAAAGTAGAAGAGAGAAGAACAGGGTGATCGCTATGAAAATTAACGGCT
ACAAACCAACCGGTGAAGTA

Product: response regulator receiver modulated CheB methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MLPVKVLVVDDSSLMRRLISRLLEEDKGIKVIGTAADGLEALQQIKALRPDVVTMDVEMPRLDGIATLRRLMVDFPTPAV
MLSAHTHEGARATMDALSAGAVDFVAKPTSSAELPRMVEDLKTKVKVAARVSLRRVRTTLTPPPAPLARPKPATTAAPGS
AKAKPQTQVRRQPYCGKIDLVVIGCSTGGPAALQQIIPYLPANLPAGVVVVQHIPVGFSKSMAEHLDKKSAISVRHAAEG
DAIKAGQVLVAPAGYDLNFKAKGNGSTVALSNQGAPLAPGGFRPSVDWVMKSAAEVYGCRTLAVLLTGMGRDGARGMLAI
KEQGGPTIAEHESTCVVYGMPKAAYDIGAAGKMVPLPQIAQEIQAFFDV

Sequences:

>Translated_369_residues
MLPVKVLVVDDSSLMRRLISRLLEEDKGIKVIGTAADGLEALQQIKALRPDVVTMDVEMPRLDGIATLRRLMVDFPTPAV
MLSAHTHEGARATMDALSAGAVDFVAKPTSSAELPRMVEDLKTKVKVAARVSLRRVRTTLTPPPAPLARPKPATTAAPGS
AKAKPQTQVRRQPYCGKIDLVVIGCSTGGPAALQQIIPYLPANLPAGVVVVQHIPVGFSKSMAEHLDKKSAISVRHAAEG
DAIKAGQVLVAPAGYDLNFKAKGNGSTVALSNQGAPLAPGGFRPSVDWVMKSAAEVYGCRTLAVLLTGMGRDGARGMLAI
KEQGGPTIAEHESTCVVYGMPKAAYDIGAAGKMVPLPQIAQEIQAFFDV
>Mature_369_residues
MLPVKVLVVDDSSLMRRLISRLLEEDKGIKVIGTAADGLEALQQIKALRPDVVTMDVEMPRLDGIATLRRLMVDFPTPAV
MLSAHTHEGARATMDALSAGAVDFVAKPTSSAELPRMVEDLKTKVKVAARVSLRRVRTTLTPPPAPLARPKPATTAAPGS
AKAKPQTQVRRQPYCGKIDLVVIGCSTGGPAALQQIIPYLPANLPAGVVVVQHIPVGFSKSMAEHLDKKSAISVRHAAEG
DAIKAGQVLVAPAGYDLNFKAKGNGSTVALSNQGAPLAPGGFRPSVDWVMKSAAEVYGCRTLAVLLTGMGRDGARGMLAI
KEQGGPTIAEHESTCVVYGMPKAAYDIGAAGKMVPLPQIAQEIQAFFDV

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=367, Percent_Identity=36.5122615803815, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI87082052, Length=121, Percent_Identity=28.9256198347107, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 38843; Mature: 38843

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPVKVLVVDDSSLMRRLISRLLEEDKGIKVIGTAADGLEALQQIKALRPDVVTMDVEMP
CCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCEEEEECCCC
RLDGIATLRRLMVDFPTPAVMLSAHTHEGARATMDALSAGAVDFVAKPTSSAELPRMVED
CCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHH
LKTKVKVAARVSLRRVRTTLTPPPAPLARPKPATTAAPGSAKAKPQTQVRRQPYCGKIDL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEE
VVIGCSTGGPAALQQIIPYLPANLPAGVVVVQHIPVGFSKSMAEHLDKKSAISVRHAAEG
EEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHCCHHHHEEEEECCCC
DAIKAGQVLVAPAGYDLNFKAKGNGSTVALSNQGAPLAPGGFRPSVDWVMKSAAEVYGCR
CCEECCCEEEEECCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
TLAVLLTGMGRDGARGMLAIKEQGGPTIAEHESTCVVYGMPKAAYDIGAAGKMVPLPQIA
HHHHHHHCCCCCCCCCEEEEECCCCCEEECCCCEEEEEECCHHHHHCCCCCCCCCCHHHH
QEIQAFFDV
HHHHHHHCC
>Mature Secondary Structure
MLPVKVLVVDDSSLMRRLISRLLEEDKGIKVIGTAADGLEALQQIKALRPDVVTMDVEMP
CCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCEEEEECCCC
RLDGIATLRRLMVDFPTPAVMLSAHTHEGARATMDALSAGAVDFVAKPTSSAELPRMVED
CCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHH
LKTKVKVAARVSLRRVRTTLTPPPAPLARPKPATTAAPGSAKAKPQTQVRRQPYCGKIDL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEE
VVIGCSTGGPAALQQIIPYLPANLPAGVVVVQHIPVGFSKSMAEHLDKKSAISVRHAAEG
EEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHCCHHHHEEEEECCCC
DAIKAGQVLVAPAGYDLNFKAKGNGSTVALSNQGAPLAPGGFRPSVDWVMKSAAEVYGCR
CCEECCCEEEEECCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
TLAVLLTGMGRDGARGMLAIKEQGGPTIAEHESTCVVYGMPKAAYDIGAAGKMVPLPQIA
HHHHHHHCCCCCCCCCEEEEECCCCCEEECCCCEEEEEECCHHHHHCCCCCCCCCCHHHH
QEIQAFFDV
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA