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The map label for this gene is fliY [H]

Identifier: 134300219

GI number: 134300219

Start: 2603947

End: 2605182

Strand: Reverse

Name: fliY [H]

Synonym: Dred_2380

Alternate gene names: 134300219

Gene position: 2605182-2603947 (Counterclockwise)

Preceding gene: 134300220

Following gene: 134300216

Centisome position: 72.2

GC content: 44.34

Gene sequence:

>1236_bases
ATGTCTAAACTATTAAGCCAGGAAGAAATTGACGCTTTAATGAAAGGGCAAGACCTGGGAAATGAACCGGATCCTCTGGG
GAATCAGTCAGAAATGTCTGATACAGTAATTGAACCGGAAAATACGCAGCCTAACTTGGCTAAACCAGAAGCATTGGCAG
AGGAAGCGAATTATTGTAGTCTAATGACCTTGGAAGAAATGGATGCCCTGGGGGAGATTGGCAATATCTCAATGGGCTCG
GCCTCCACAACTCTGTCAGAACTTTTAAGCCAGAAGGTAAATATCACCAGCCCAAGGGTTAAGATACAAACAAAACAGCA
ATTATTCGATTCCTTTAATATTCCTTATCTCGTCATCAAGGTTGACTTTAATGAAGGATTAAACGGTTATAATGTATTGG
TGATTAAGCTTAATGATGCTGCCACTATGGCCAGCTTAATGATGGGGGGAGATGGTACCCCCATGTCCGAAGAAATCTCG
GAATTAGAAATTAGTGCAGCATCCGAAGCCATGAATATGATGATTGGAACTGCGGCAACATCCCTGTCTCAAATGTTCCA
ACGGACCATTAATATATCACCGCCCCAAACAAATTTGTTAAGATCAAAGGGAGATCCACTGGCTCAACCACCCCAGGATA
TCGAAGATGTTATTGTTGTGGTTTCCTTTGATATGAAAATTGGAGATCTGGTGGACACAGAGATTATGCAGATTATGTCG
GTGGAGACTGCCAAAGAAGAAGCCCATCTTTTGCTGAAGGACATTATGGGAGGCACAGAAGAGCAGGTGGAAGCTCCCAT
GGTGCCAACAGAAGCAGCTACGTCAGCCACCAGCATACCTGGATCTGACGATAGGGAATCGGATGAATTGGCTGGCATAA
TGATGCAGGAAACAGCACCTCCTCCGACTCCTGCCATGCCGCCGCAAGCAGCACCGATTAAACAGACGTCCTTGGCTTCC
CTGGAACAAAGAAACTTGGATTTAATCTTAGATATTCCGCTAAAGGTAAGTGTTATTCTGGGCAGAACCAAGCGTCCCAT
TAAAGATGTGTTGAAAATTGCTCCGGGATCAGTGGTGGAGCTGGATTCTCTGGCTGATGAACCAGTGGATATTCTGGTAA
ACGGAACCCTGGTGGCTACTGGAGAAGTGGTGGTGGTTAACGAAAATTTTGGTATTCGTATCACCAATATCATTAGTCCC
ATGGAACGGGTTAAACGGTTAAGTAAATATAATTAG

Upstream 100 bases:

>100_bases
ATGTATGTGGATGAAGAACTTAAGTACAAAGTGCAAGTGGGAACGGTCGGCCAGAGCTTGGCGGTTCAGGTGACCTCACT
GGCCGAGGAGGCGTGGGAAA

Downstream 100 bases:

>100_bases
CCGTTAGCCCTGAGTCTTAGTCCTTAGCTAACAGATAATATGTCCTTTAAGGCACCAATAATAGAATGAAAATAAGCATT
TTAAAGGCCAATGGCAATAT

Product: flagellar motor switch protein

Products: NA

Alternate protein names: CheY-P phosphatase FliY [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MSKLLSQEEIDALMKGQDLGNEPDPLGNQSEMSDTVIEPENTQPNLAKPEALAEEANYCSLMTLEEMDALGEIGNISMGS
ASTTLSELLSQKVNITSPRVKIQTKQQLFDSFNIPYLVIKVDFNEGLNGYNVLVIKLNDAATMASLMMGGDGTPMSEEIS
ELEISAASEAMNMMIGTAATSLSQMFQRTINISPPQTNLLRSKGDPLAQPPQDIEDVIVVVSFDMKIGDLVDTEIMQIMS
VETAKEEAHLLLKDIMGGTEEQVEAPMVPTEAATSATSIPGSDDRESDELAGIMMQETAPPPTPAMPPQAAPIKQTSLAS
LEQRNLDLILDIPLKVSVILGRTKRPIKDVLKIAPGSVVELDSLADEPVDILVNGTLVATGEVVVVNENFGIRITNIISP
MERVKRLSKYN

Sequences:

>Translated_411_residues
MSKLLSQEEIDALMKGQDLGNEPDPLGNQSEMSDTVIEPENTQPNLAKPEALAEEANYCSLMTLEEMDALGEIGNISMGS
ASTTLSELLSQKVNITSPRVKIQTKQQLFDSFNIPYLVIKVDFNEGLNGYNVLVIKLNDAATMASLMMGGDGTPMSEEIS
ELEISAASEAMNMMIGTAATSLSQMFQRTINISPPQTNLLRSKGDPLAQPPQDIEDVIVVVSFDMKIGDLVDTEIMQIMS
VETAKEEAHLLLKDIMGGTEEQVEAPMVPTEAATSATSIPGSDDRESDELAGIMMQETAPPPTPAMPPQAAPIKQTSLAS
LEQRNLDLILDIPLKVSVILGRTKRPIKDVLKIAPGSVVELDSLADEPVDILVNGTLVATGEVVVVNENFGIRITNIISP
MERVKRLSKYN
>Mature_410_residues
SKLLSQEEIDALMKGQDLGNEPDPLGNQSEMSDTVIEPENTQPNLAKPEALAEEANYCSLMTLEEMDALGEIGNISMGSA
STTLSELLSQKVNITSPRVKIQTKQQLFDSFNIPYLVIKVDFNEGLNGYNVLVIKLNDAATMASLMMGGDGTPMSEEISE
LEISAASEAMNMMIGTAATSLSQMFQRTINISPPQTNLLRSKGDPLAQPPQDIEDVIVVVSFDMKIGDLVDTEIMQIMSV
ETAKEEAHLLLKDIMGGTEEQVEAPMVPTEAATSATSIPGSDDRESDELAGIMMQETAPPPTPAMPPQAAPIKQTSLASL
EQRNLDLILDIPLKVSVILGRTKRPIKDVLKIAPGSVVELDSLADEPVDILVNGTLVATGEVVVVNENFGIRITNIISPM
ERVKRLSKYN

Specific function: Component of the flagellar switch. Binds CheY-P and increases its hydrolysis rate in vitro. May function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P whereas CheC may function after addition of an attr

COG id: COG1776

COG function: function code NT; Chemotaxis protein CheC, inhibitor of MCP methylation

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=The switch is localized at the base of the flagellar motor, in or near the C-ring, attached to the MS-ring (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FliN/MopA/SpaO family [H]

Homologues:

Organism=Escherichia coli, GI1788256, Length=86, Percent_Identity=58.1395348837209, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007597
- InterPro:   IPR012826
- InterPro:   IPR001172
- InterPro:   IPR001543 [H]

Pfam domain/function: PF04509 CheC; PF01052 SpoA [H]

EC number: NA

Molecular weight: Translated: 44381; Mature: 44250

Theoretical pI: Translated: 4.00; Mature: 4.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLLSQEEIDALMKGQDLGNEPDPLGNQSEMSDTVIEPENTQPNLAKPEALAEEANYCS
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHCCCCEECCCCCCCCCCCCHHHHHCCCCEE
LMTLEEMDALGEIGNISMGSASTTLSELLSQKVNITSPRVKIQTKQQLFDSFNIPYLVIK
EEEHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHCCCCCEEEEE
VDFNEGLNGYNVLVIKLNDAATMASLMMGGDGTPMSEEISELEISAASEAMNMMIGTAAT
EECCCCCCCEEEEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLSQMFQRTINISPPQTNLLRSKGDPLAQPPQDIEDVIVVVSFDMKIGDLVDTEIMQIMS
HHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
VETAKEEAHLLLKDIMGGTEEQVEAPMVPTEAATSATSIPGSDDRESDELAGIMMQETAP
HHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHCCCCCCCCCCCCCCCHHHHCCCEECCCC
PPTPAMPPQAAPIKQTSLASLEQRNLDLILDIPLKVSVILGRTKRPIKDVLKIAPGSVVE
CCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCHHHHHHHCCCCEEE
LDSLADEPVDILVNGTLVATGEVVVVNENFGIRITNIISPMERVKRLSKYN
HHHHCCCCEEEEEECEEEEECEEEEEECCCCEEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKLLSQEEIDALMKGQDLGNEPDPLGNQSEMSDTVIEPENTQPNLAKPEALAEEANYCS
CCCCCHHHHHHHHCCCCCCCCCCCCCCCHHCCCCEECCCCCCCCCCCCHHHHHCCCCEE
LMTLEEMDALGEIGNISMGSASTTLSELLSQKVNITSPRVKIQTKQQLFDSFNIPYLVIK
EEEHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHCCCCCEEEEE
VDFNEGLNGYNVLVIKLNDAATMASLMMGGDGTPMSEEISELEISAASEAMNMMIGTAAT
EECCCCCCCEEEEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLSQMFQRTINISPPQTNLLRSKGDPLAQPPQDIEDVIVVVSFDMKIGDLVDTEIMQIMS
HHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
VETAKEEAHLLLKDIMGGTEEQVEAPMVPTEAATSATSIPGSDDRESDELAGIMMQETAP
HHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHCCCCCCCCCCCCCCCHHHHCCCEECCCC
PPTPAMPPQAAPIKQTSLASLEQRNLDLILDIPLKVSVILGRTKRPIKDVLKIAPGSVVE
CCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCEEEEEECCCCCCHHHHHHHCCCCEEE
LDSLADEPVDILVNGTLVATGEVVVVNENFGIRITNIISPMERVKRLSKYN
HHHHCCCCEEEEEECEEEEECEEEEEECCCCEEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1447979; 9384377; 1898932 [H]