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The map label for this gene is atoS [H]

Identifier: 134300132

GI number: 134300132

Start: 2506525

End: 2508873

Strand: Reverse

Name: atoS [H]

Synonym: Dred_2293

Alternate gene names: 134300132

Gene position: 2508873-2506525 (Counterclockwise)

Preceding gene: 134300133

Following gene: 134300131

Centisome position: 69.53

GC content: 39.04

Gene sequence:

>2349_bases
TTGTATCGAAAGCTAAGGGATAGGTTATTTCCATTACAAATAACGAAACGCTTTTATCTTGGTATGGCTTTTTTGATCAT
TGTACCCATTTTAGTTATGGAAATTCTCGATCAAATTAGCTTTATGGAAGAAAGAAAAATAATCAAAGAGAAGGAGCTTT
TTGCCGTTGTTTGTCATTTAAACCGCTCTTTGCAAGGTTCTTATGATGATATACTTAAACAATACAATATAGAACCTTCT
CCCCAAGCAAAGTTGTTAATTCTCAACTCTGTTTTACAGCCAATAATTAATCAAATTGCCTTCTGTCACACGAATCTTAT
AATAGGTTATTATTCCAGCGAATTGGATAGTATTGTGGCCTCAAATCTAGATTACCCCACCGGCAAGCTTTATCCACTAC
CCCACACGCTACCCTATTTTGATATTTATAAAACTGGCAACCCGCAATACTTCTATGATCAAGATTTTTTTCATAAAAAC
AGCCATGAAACCCTTAGCCTGGTCTATCCCCTTCATCGGCAAGGCAAGCTGATTGGTCATGTGTGGGCCAGTCGAGATAT
GGATAGTTTCTATCAAGAAGCCTTAGCCAGAAGGAAAAACACTCTTCTGGCCGGTTTTATCATGCTTTTTGGCAGCATAT
TCTTATCCTGGATATTTTTTACTAGATTCAAAAGAGATTTAAACCATTTTGCCAATGCCATCGGCACAAATAACTTGAGG
ATTTCCAGTGATTCTTTACCGGAATTAAACCCCCTGGTGGAACTAATTTATAAAAGAGAAAATGAACTAAAAAGAGAACT
GGAAATCAGTTCTTCCATTGCAGAGTTATCCAGTAAGGTTATTTCAACGGCTTCCTTCAATGAAGTCACAGAACATATAT
TAGACCAGGCCAGGAAATTTACCGACAGCAAACTGGGCTATGTAGGGTGCCTTGACCCTATGACAGGGTGTTTAACTATC
TCATGTCTGCCTAAAGGAATAGGCGGGGACATACATAGTGGAAAAGAGGTATTTATAAAATATAAAGGTCTATGGGGATG
GGTGCTAAAGAATAAAAAATCTCTCCTTTCAAATAATCCGGAACAAGATTACAGAGCCCAGGTTACTCTTCCAGGTCATG
TTAAAATAACCAGATTTATTGCTGTACCTGCCATTATTGACGATCAATTAGTTGGTCAAATTGCTTTAGCTAATGCCAAA
AGGGATTATACCCCGGGGGATCTGGTGTTGGTAGAAAGATTTGCACGTCTTTTAGTTATTTTAATTCATCGGGAGCACAG
GGAAGAAGCTTTACGTATGTCGGAGGACCGCTTTGCCAAAGCATTTAACACCAATCCCTGCATGGTATCTATCACCACCC
TTGATGAAGGTCGTTTTATTGATGTCAACAAAAGTTTTTTACAAACCCTGGGCTACGAACGTGAGGATGTCATTGGACAT
ACGTCCCAGGAAATTGATATTGGTATAAAGTCAAAAAGAAAGGAAGTTATTAATAGCATTAAACAAGGAAAACCCGTGCA
CAATCTTGAGGTAACTTTTTATGGAAGAGAAGGGAACAGGATGGTTGGGTTATATTCTGCCGAATTAATTAAATTGTCTG
GGGAGTCTTGCCTTCTTTCGGTGGTGAATGATATTACCAAACGTAAACAGTTAGAAAAAGAAATGATACGACTGGATCGC
TTGAATATGGTAGGCGAGATGGCTGCAGGCATTGCCCACGAGGTAAGGAATCCCTTAACTACGGTAAGGGGCTTCCTGCA
AATGCTCGGGAAGAAAAATGACAATGGTAAGCTTCAAGAATATTATGCATTAATGATTGAGGAGCTTGACCGGGCAAACA
CAATTATCTCAGAGTTTTTATCCACTGCCCGAAACAAACCGGATAAGCTGGAGCTAGAAGACCTTAACACAATTATTGAC
ACCTTGTTCCCCTTAATCGCAGCTGACGCCATGAATTCTGATTGCAATGTGGTGAGGGAGTTGACAAATATTTCTCCAAT
TTTACTGAACCAAAAGGAAATACGACAGCTTATTTTAAATCTTGCCCACAACAGTTTAGAGGCCATGACACCTGGTGGAA
CCCTTACAATCAAGACTTTTATGGTTGGAGAGGAGATTATTTTGTCAATGGCCGATACGGGTAAAGGAATTGAAACCGAA
ATATTGGATAAATTGGGAACACCGTTCTTTACAACCAAAGAGAATGGCACTGGTTTAGGGCTGGCAGTTTGCTATGGAAT
TGTTAGGCGACATCATGCATCCATAGAAATTGATACAAGTCCCAAGGGAACAACATTCTATATTAAATTTAAACAGTTTA
AAGGTGTTGACAATGAATATGCTGTTTGA

Upstream 100 bases:

>100_bases
AAAATAAATTGCGACAAAAAATATTAAATTTTACCAAGGTGATTTAATAAAAGTCATCGAAATAATCATGAAAATTCTGA
CTATCGGATGGTGTAGGGAA

Downstream 100 bases:

>100_bases
CTTTAAAGAAGGGGGCAATGCCTCCTTTTTAGTGTTTTGGGAAAGCTTGCCTAAGGTATTGAGAAAAAGTAATCTTAAAT
TTGTAAATGGTTAACTCCTT

Product: nitrogen-specific signal transduction histidine kinase NtrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 782; Mature: 782

Protein sequence:

>782_residues
MYRKLRDRLFPLQITKRFYLGMAFLIIVPILVMEILDQISFMEERKIIKEKELFAVVCHLNRSLQGSYDDILKQYNIEPS
PQAKLLILNSVLQPIINQIAFCHTNLIIGYYSSELDSIVASNLDYPTGKLYPLPHTLPYFDIYKTGNPQYFYDQDFFHKN
SHETLSLVYPLHRQGKLIGHVWASRDMDSFYQEALARRKNTLLAGFIMLFGSIFLSWIFFTRFKRDLNHFANAIGTNNLR
ISSDSLPELNPLVELIYKRENELKRELEISSSIAELSSKVISTASFNEVTEHILDQARKFTDSKLGYVGCLDPMTGCLTI
SCLPKGIGGDIHSGKEVFIKYKGLWGWVLKNKKSLLSNNPEQDYRAQVTLPGHVKITRFIAVPAIIDDQLVGQIALANAK
RDYTPGDLVLVERFARLLVILIHREHREEALRMSEDRFAKAFNTNPCMVSITTLDEGRFIDVNKSFLQTLGYEREDVIGH
TSQEIDIGIKSKRKEVINSIKQGKPVHNLEVTFYGREGNRMVGLYSAELIKLSGESCLLSVVNDITKRKQLEKEMIRLDR
LNMVGEMAAGIAHEVRNPLTTVRGFLQMLGKKNDNGKLQEYYALMIEELDRANTIISEFLSTARNKPDKLELEDLNTIID
TLFPLIAADAMNSDCNVVRELTNISPILLNQKEIRQLILNLAHNSLEAMTPGGTLTIKTFMVGEEIILSMADTGKGIETE
ILDKLGTPFFTTKENGTGLGLAVCYGIVRRHHASIEIDTSPKGTTFYIKFKQFKGVDNEYAV

Sequences:

>Translated_782_residues
MYRKLRDRLFPLQITKRFYLGMAFLIIVPILVMEILDQISFMEERKIIKEKELFAVVCHLNRSLQGSYDDILKQYNIEPS
PQAKLLILNSVLQPIINQIAFCHTNLIIGYYSSELDSIVASNLDYPTGKLYPLPHTLPYFDIYKTGNPQYFYDQDFFHKN
SHETLSLVYPLHRQGKLIGHVWASRDMDSFYQEALARRKNTLLAGFIMLFGSIFLSWIFFTRFKRDLNHFANAIGTNNLR
ISSDSLPELNPLVELIYKRENELKRELEISSSIAELSSKVISTASFNEVTEHILDQARKFTDSKLGYVGCLDPMTGCLTI
SCLPKGIGGDIHSGKEVFIKYKGLWGWVLKNKKSLLSNNPEQDYRAQVTLPGHVKITRFIAVPAIIDDQLVGQIALANAK
RDYTPGDLVLVERFARLLVILIHREHREEALRMSEDRFAKAFNTNPCMVSITTLDEGRFIDVNKSFLQTLGYEREDVIGH
TSQEIDIGIKSKRKEVINSIKQGKPVHNLEVTFYGREGNRMVGLYSAELIKLSGESCLLSVVNDITKRKQLEKEMIRLDR
LNMVGEMAAGIAHEVRNPLTTVRGFLQMLGKKNDNGKLQEYYALMIEELDRANTIISEFLSTARNKPDKLELEDLNTIID
TLFPLIAADAMNSDCNVVRELTNISPILLNQKEIRQLILNLAHNSLEAMTPGGTLTIKTFMVGEEIILSMADTGKGIETE
ILDKLGTPFFTTKENGTGLGLAVCYGIVRRHHASIEIDTSPKGTTFYIKFKQFKGVDNEYAV
>Mature_782_residues
MYRKLRDRLFPLQITKRFYLGMAFLIIVPILVMEILDQISFMEERKIIKEKELFAVVCHLNRSLQGSYDDILKQYNIEPS
PQAKLLILNSVLQPIINQIAFCHTNLIIGYYSSELDSIVASNLDYPTGKLYPLPHTLPYFDIYKTGNPQYFYDQDFFHKN
SHETLSLVYPLHRQGKLIGHVWASRDMDSFYQEALARRKNTLLAGFIMLFGSIFLSWIFFTRFKRDLNHFANAIGTNNLR
ISSDSLPELNPLVELIYKRENELKRELEISSSIAELSSKVISTASFNEVTEHILDQARKFTDSKLGYVGCLDPMTGCLTI
SCLPKGIGGDIHSGKEVFIKYKGLWGWVLKNKKSLLSNNPEQDYRAQVTLPGHVKITRFIAVPAIIDDQLVGQIALANAK
RDYTPGDLVLVERFARLLVILIHREHREEALRMSEDRFAKAFNTNPCMVSITTLDEGRFIDVNKSFLQTLGYEREDVIGH
TSQEIDIGIKSKRKEVINSIKQGKPVHNLEVTFYGREGNRMVGLYSAELIKLSGESCLLSVVNDITKRKQLEKEMIRLDR
LNMVGEMAAGIAHEVRNPLTTVRGFLQMLGKKNDNGKLQEYYALMIEELDRANTIISEFLSTARNKPDKLELEDLNTIID
TLFPLIAADAMNSDCNVVRELTNISPILLNQKEIRQLILNLAHNSLEAMTPGGTLTIKTFMVGEEIILSMADTGKGIETE
ILDKLGTPFFTTKENGTGLGLAVCYGIVRRHHASIEIDTSPKGTTFYIKFKQFKGVDNEYAV

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=317, Percent_Identity=29.3375394321767, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1790436, Length=266, Percent_Identity=31.9548872180451, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1790300, Length=236, Percent_Identity=26.271186440678, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1786600, Length=240, Percent_Identity=25.4166666666667, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI145693157, Length=275, Percent_Identity=24.7272727272727, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1789808, Length=207, Percent_Identity=26.5700483091787, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88848; Mature: 88848

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRKLRDRLFPLQITKRFYLGMAFLIIVPILVMEILDQISFMEERKIIKEKELFAVVCHL
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRSLQGSYDDILKQYNIEPSPQAKLLILNSVLQPIINQIAFCHTNLIIGYYSSELDSIVA
CCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHH
SNLDYPTGKLYPLPHTLPYFDIYKTGNPQYFYDQDFFHKNSHETLSLVYPLHRQGKLIGH
CCCCCCCCCEECCCCCCCCEEEEECCCCCEEECCHHHCCCCCCEEEEEECCCCCCCEEEH
VWASRDMDSFYQEALARRKNTLLAGFIMLFGSIFLSWIFFTRFKRDLNHFANAIGTNNLR
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
ISSDSLPELNPLVELIYKRENELKRELEISSSIAELSSKVISTASFNEVTEHILDQARKF
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDSKLGYVGCLDPMTGCLTISCLPKGIGGDIHSGKEVFIKYKGLWGWVLKNKKSLLSNNP
CCCCCCEEEECCCHHHHEEEEECCCCCCCCCCCCCEEEEEEECEEEHHHHCCHHHHCCCC
EQDYRAQVTLPGHVKITRFIAVPAIIDDQLVGQIALANAKRDYTPGDLVLVERFARLLVI
CCCCEEEEEECCCEEEEEEEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LIHREHREEALRMSEDRFAKAFNTNPCMVSITTLDEGRFIDVNKSFLQTLGYEREDVIGH
HHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEEEECCCCEEECCHHHHHHCCCCCHHHCCC
TSQEIDIGIKSKRKEVINSIKQGKPVHNLEVTFYGREGNRMVGLYSAELIKLSGESCLLS
CCCCEECCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEEEEEEEECCCHHHHH
VVNDITKRKQLEKEMIRLDRLNMVGEMAAGIAHEVRNPLTTVRGFLQMLGKKNDNGKLQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
YYALMIEELDRANTIISEFLSTARNKPDKLELEDLNTIIDTLFPLIAADAMNSDCNVVRE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LTNISPILLNQKEIRQLILNLAHNSLEAMTPGGTLTIKTFMVGEEIILSMADTGKGIETE
HHCCCHHEECHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECHHHHHHHHCCCCCCHHH
ILDKLGTPFFTTKENGTGLGLAVCYGIVRRHHASIEIDTSPKGTTFYIKFKQFKGVDNEY
HHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEHHHCCCCCCC
AV
CC
>Mature Secondary Structure
MYRKLRDRLFPLQITKRFYLGMAFLIIVPILVMEILDQISFMEERKIIKEKELFAVVCHL
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NRSLQGSYDDILKQYNIEPSPQAKLLILNSVLQPIINQIAFCHTNLIIGYYSSELDSIVA
CCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHH
SNLDYPTGKLYPLPHTLPYFDIYKTGNPQYFYDQDFFHKNSHETLSLVYPLHRQGKLIGH
CCCCCCCCCEECCCCCCCCEEEEECCCCCEEECCHHHCCCCCCEEEEEECCCCCCCEEEH
VWASRDMDSFYQEALARRKNTLLAGFIMLFGSIFLSWIFFTRFKRDLNHFANAIGTNNLR
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
ISSDSLPELNPLVELIYKRENELKRELEISSSIAELSSKVISTASFNEVTEHILDQARKF
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDSKLGYVGCLDPMTGCLTISCLPKGIGGDIHSGKEVFIKYKGLWGWVLKNKKSLLSNNP
CCCCCCEEEECCCHHHHEEEEECCCCCCCCCCCCCEEEEEEECEEEHHHHCCHHHHCCCC
EQDYRAQVTLPGHVKITRFIAVPAIIDDQLVGQIALANAKRDYTPGDLVLVERFARLLVI
CCCCEEEEEECCCEEEEEEEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
LIHREHREEALRMSEDRFAKAFNTNPCMVSITTLDEGRFIDVNKSFLQTLGYEREDVIGH
HHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEEEECCCCEEECCHHHHHHCCCCCHHHCCC
TSQEIDIGIKSKRKEVINSIKQGKPVHNLEVTFYGREGNRMVGLYSAELIKLSGESCLLS
CCCCEECCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEEEEEEEECCCHHHHH
VVNDITKRKQLEKEMIRLDRLNMVGEMAAGIAHEVRNPLTTVRGFLQMLGKKNDNGKLQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
YYALMIEELDRANTIISEFLSTARNKPDKLELEDLNTIIDTLFPLIAADAMNSDCNVVRE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LTNISPILLNQKEIRQLILNLAHNSLEAMTPGGTLTIKTFMVGEEIILSMADTGKGIETE
HHCCCHHEECHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECHHHHHHHHCCCCCCHHH
ILDKLGTPFFTTKENGTGLGLAVCYGIVRRHHASIEIDTSPKGTTFYIKFKQFKGVDNEY
HHHHHCCCCEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEEHHHCCCCCCC
AV
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]