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The map label for this gene is moeZ [H]

Identifier: 134300104

GI number: 134300104

Start: 2477753

End: 2478529

Strand: Reverse

Name: moeZ [H]

Synonym: Dred_2264

Alternate gene names: 134300104

Gene position: 2478529-2477753 (Counterclockwise)

Preceding gene: 134300105

Following gene: 134300103

Centisome position: 68.69

GC content: 46.46

Gene sequence:

>777_bases
TTGTCCATTGAGCAGAAGAAACGCTATCACCGAAATATTATGTTGTCTGGTGTAGGAGAAGAAGGCCAGCTTAAACTACT
TCATTCGTCGGTATTAGTGGTGGGAACCGGCGGCTTAGGATCTCCGGTGGCCTATTATCTGGCAGCTGCCGGTATTGGAC
GACTGGGTTTGATCGATGCAGATGTGGTGGATTGCTCCAACCTACAAAGACAAATTGTACACGGCACGCCAGATATAGGT
CGTTTCAAGGTAGAATCCGCCCGTGAGAAATTACTGCAAATTAATCCGGACATTGATATTAGAACCTACCCCCATCGTAT
GACGGAGGATAATGCAGAAGAACTGGTGGAGCAATACCATATCGTAGTGGATGCTACCGACAACTTGGAAAGTCGCTATA
TCCTGAATAAAGCCTGCATCAATCAAAAGAAGCCATTTATCTATGGAGGTGTTCTTTCTATGGTTGGTCAGGTTATGACC
ATTGTTCCTGGAAAGGGACCTTGTTTCCGCTGTATTTTTAGGGAGTTACCCGGTAAACGAAGGCCAAAGGGCACAGATGA
AGTGGGGATTCTGGGATCGGTGGCCGGAACAATTGGTTCCATCCAGGCCACGGAGGTCATTAAATATCTACTTGGTCAAG
GGGAGCTTTTAATCGGACGCCTGCTAACCATGGATGCACGATCCATGTCCTTTGCAGATGTGGAAGTGAAAAAGGATGCC
CAATGCCCAGATTGTGGCCATCTAAAAAGGGATTATGGTGAGAAACCCATATGTTAA

Upstream 100 bases:

>100_bases
AGTGGGGATACCGCTATTTGATCTGAATGATATTGTTGGTGTGGCCAACCTCATCGAGAACTGTTTTCTGCAACCTAGTG
AAAAGTCAGCACCGAAGACT

Downstream 100 bases:

>100_bases
ACCTGGATAATATGCCAGGTTTTTTATTTAAAGGAATTTCGTGGAGGAAAATGAGTTAATTTGTCGAAATACAGCATTAA
AATACATTGGAGCTAATTAT

Product: UBA/THIF-type NAD/FAD binding protein

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSIEQKKRYHRNIMLSGVGEEGQLKLLHSSVLVVGTGGLGSPVAYYLAAAGIGRLGLIDADVVDCSNLQRQIVHGTPDIG
RFKVESAREKLLQINPDIDIRTYPHRMTEDNAEELVEQYHIVVDATDNLESRYILNKACINQKKPFIYGGVLSMVGQVMT
IVPGKGPCFRCIFRELPGKRRPKGTDEVGILGSVAGTIGSIQATEVIKYLLGQGELLIGRLLTMDARSMSFADVEVKKDA
QCPDCGHLKRDYGEKPIC

Sequences:

>Translated_258_residues
MSIEQKKRYHRNIMLSGVGEEGQLKLLHSSVLVVGTGGLGSPVAYYLAAAGIGRLGLIDADVVDCSNLQRQIVHGTPDIG
RFKVESAREKLLQINPDIDIRTYPHRMTEDNAEELVEQYHIVVDATDNLESRYILNKACINQKKPFIYGGVLSMVGQVMT
IVPGKGPCFRCIFRELPGKRRPKGTDEVGILGSVAGTIGSIQATEVIKYLLGQGELLIGRLLTMDARSMSFADVEVKKDA
QCPDCGHLKRDYGEKPIC
>Mature_257_residues
SIEQKKRYHRNIMLSGVGEEGQLKLLHSSVLVVGTGGLGSPVAYYLAAAGIGRLGLIDADVVDCSNLQRQIVHGTPDIGR
FKVESAREKLLQINPDIDIRTYPHRMTEDNAEELVEQYHIVVDATDNLESRYILNKACINQKKPFIYGGVLSMVGQVMTI
VPGKGPCFRCIFRELPGKRRPKGTDEVGILGSVAGTIGSIQATEVIKYLLGQGELLIGRLLTMDARSMSFADVEVKKDAQ
CPDCGHLKRDYGEKPIC

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=226, Percent_Identity=41.1504424778761, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI4885649, Length=153, Percent_Identity=35.9477124183007, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI38045944, Length=170, Percent_Identity=31.1764705882353, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI38045942, Length=170, Percent_Identity=31.1764705882353, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI38327032, Length=234, Percent_Identity=25.2136752136752, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI23510338, Length=170, Percent_Identity=24.7058823529412, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI23510340, Length=170, Percent_Identity=24.7058823529412, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI13376212, Length=234, Percent_Identity=25.2136752136752, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1787048, Length=248, Percent_Identity=38.3064516129032, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI87082356, Length=246, Percent_Identity=38.2113821138211, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1789177, Length=201, Percent_Identity=29.3532338308458, Blast_Score=71, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17540406, Length=248, Percent_Identity=35.0806451612903, Blast_Score=163, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI193203301, Length=154, Percent_Identity=31.8181818181818, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17508819, Length=233, Percent_Identity=27.8969957081545, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71984476, Length=172, Percent_Identity=27.906976744186, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321903, Length=214, Percent_Identity=36.4485981308411, Blast_Score=155, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6320598, Length=173, Percent_Identity=30.635838150289, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322639, Length=195, Percent_Identity=26.1538461538462, Blast_Score=72, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6325323, Length=163, Percent_Identity=24.5398773006135, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6325438, Length=115, Percent_Identity=26.9565217391304, Blast_Score=65, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6321790, Length=119, Percent_Identity=31.0924369747899, Blast_Score=62, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24582879, Length=238, Percent_Identity=44.1176470588235, Blast_Score=203, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24660640, Length=155, Percent_Identity=35.4838709677419, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI20129973, Length=201, Percent_Identity=28.8557213930348, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28573937, Length=164, Percent_Identity=26.8292682926829, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24641311, Length=258, Percent_Identity=28.2945736434109, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 28327; Mature: 28196

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIEQKKRYHRNIMLSGVGEEGQLKLLHSSVLVVGTGGLGSPVAYYLAAAGIGRLGLIDA
CCCHHHHHHHHCEEEECCCCCCCEEEEECEEEEEECCCCCHHHHHHHHHHCCCCCCCCCC
DVVDCSNLQRQIVHGTPDIGRFKVESAREKLLQINPDIDIRTYPHRMTEDNAEELVEQYH
CHHCHHHHHHHHHCCCCCCCCEEHHHHHHHHEECCCCCCEEECCCCCCCCCHHHHHHHHE
IVVDATDNLESRYILNKACINQKKPFIYGGVLSMVGQVMTIVPGKGPCFRCIFRELPGKR
EEEECCCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHEECCCCCHHHHHHHHHCCCCC
RPKGTDEVGILGSVAGTIGSIQATEVIKYLLGQGELLIGRLLTMDARSMSFADVEVKKDA
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCEEEHHHHHHCCCCCEEEEEEECCCC
QCPDCGHLKRDYGEKPIC
CCCCCCCHHHHCCCCCCC
>Mature Secondary Structure 
SIEQKKRYHRNIMLSGVGEEGQLKLLHSSVLVVGTGGLGSPVAYYLAAAGIGRLGLIDA
CCHHHHHHHHCEEEECCCCCCCEEEEECEEEEEECCCCCHHHHHHHHHHCCCCCCCCCC
DVVDCSNLQRQIVHGTPDIGRFKVESAREKLLQINPDIDIRTYPHRMTEDNAEELVEQYH
CHHCHHHHHHHHHCCCCCCCCEEHHHHHHHHEECCCCCCEEECCCCCCCCCHHHHHHHHE
IVVDATDNLESRYILNKACINQKKPFIYGGVLSMVGQVMTIVPGKGPCFRCIFRELPGKR
EEEECCCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHEECCCCCHHHHHHHHHCCCCC
RPKGTDEVGILGSVAGTIGSIQATEVIKYLLGQGELLIGRLLTMDARSMSFADVEVKKDA
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCEEEHHHHHHCCCCCEEEEEEECCCC
QCPDCGHLKRDYGEKPIC
CCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]