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The map label for this gene is pepQ [H]

Identifier: 134300059

GI number: 134300059

Start: 2425427

End: 2426620

Strand: Reverse

Name: pepQ [H]

Synonym: Dred_2216

Alternate gene names: 134300059

Gene position: 2426620-2425427 (Counterclockwise)

Preceding gene: 134300060

Following gene: 134300058

Centisome position: 67.25

GC content: 42.13

Gene sequence:

>1194_bases
TTGAAGAATAGGGTACCTTTCGCTGAATTGAAAATAAGAATGAAAAGATTTCGGGATAAAATGAAAGCTACAAATCCTGA
TTGGCAAATGGTAGTTATTTTTAGCAAAGTGAATATTTTTTACTTTACTGGCACTAGACAAGATGGTATGTTGTTGATTC
CCCGGGAGGATGAAGCAATCTATTGGGTGCGTCGCAGTTACGAACGTGCAATGGATGAATCATTTTTTCCTCATATTCAA
CCAATGAACACGTTCCGAGATGCGGCAACTTCCATTAAGCACTTTCCCAGTGTTGTTTACATGGAAACCGAGGTCGTTCC
CCTGGCTTTATATCAACGATTCAATAAAAATTTTCCCTTTAACGAGGTTAGATCAGTTGATGCACAGCTGGCTGCTATTA
GAGGGATAAAAAGCCCCTATGAACTATCTCTAATGGAACAGTCCGGTCATATTCATCAACTGGTGCTGGAGGAGTATGTA
CCTAAAATGCTGAAAGAAGGTATGAGCGAAGCAAAACTAGCCTCTGAGTTGTTTGCGGTGATGGTTGAAGAAGGTCACCA
AGGGGTAACACGTGTGAGATCTACTGATACCGAGATGGTATTAGGACATATCGCCTTTGGTGAAAGTTCCATCTACCCTT
CCTATTTTTATGGTCCCGGGGGGAGCTATGGGATGAGTCCCGCCGTACCCTTGTTAGGCAGTCGTGATCGGAAACTTAAA
AAGGGTGACCTGGTATTTATAGATATAGGCTGCGGGGTAGGTGGCTATCATACTGATAAAACCATGACCTATATGTTTGG
CGAATCCTTGCCAAAGGAAGTTATCTCTATCCACAACAAATGCGTTGATATACAGCACAGGACAGCAGAAATGCTGAAAC
CAGGTGCAATTCCATCCGAAATATATCGTTCTATAATGGGTAGTCTTGACAACGGGTTTCGAAAAAACTTTATGGGATTT
GGTAATGGTGTACTACCATTTTTAGGTCATGGAATTGGTTTAGAGATAGATGAATTGCCTATCATTGCTGAGGGCTTTAC
TGAACCATTGCAGGAAGGAATGGTTTTTGCTGTTGAACCAAAGAAAGGGATTGAAAACATCGGCATGGTGGGGGTAGAAA
ACACCTTTGTGGTTACCCCCCAGGGTGGTCGGTGTATTACCGGAGATCATCCAGGATTAATTCCAATATATTAG

Upstream 100 bases:

>100_bases
CACATAATGGTATGTAGGTTTTAAAAAAATAAAAAAAGCAGTGTATAATGAGTTAAATTACTAGAATTTCCTAAGAAAAG
TAAACAAAGGGGAATATCCA

Downstream 100 bases:

>100_bases
TAAGAAAACATTAGCAAAGCATCTGCAGAGAAGGCAGGTGCTTTTTGATTTAAATAAAAGCATATTATCTCATTTACATA
GGATAAGTTTTTTAAAAAAG

Product: peptidase M24

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MKNRVPFAELKIRMKRFRDKMKATNPDWQMVVIFSKVNIFYFTGTRQDGMLLIPREDEAIYWVRRSYERAMDESFFPHIQ
PMNTFRDAATSIKHFPSVVYMETEVVPLALYQRFNKNFPFNEVRSVDAQLAAIRGIKSPYELSLMEQSGHIHQLVLEEYV
PKMLKEGMSEAKLASELFAVMVEEGHQGVTRVRSTDTEMVLGHIAFGESSIYPSYFYGPGGSYGMSPAVPLLGSRDRKLK
KGDLVFIDIGCGVGGYHTDKTMTYMFGESLPKEVISIHNKCVDIQHRTAEMLKPGAIPSEIYRSIMGSLDNGFRKNFMGF
GNGVLPFLGHGIGLEIDELPIIAEGFTEPLQEGMVFAVEPKKGIENIGMVGVENTFVVTPQGGRCITGDHPGLIPIY

Sequences:

>Translated_397_residues
MKNRVPFAELKIRMKRFRDKMKATNPDWQMVVIFSKVNIFYFTGTRQDGMLLIPREDEAIYWVRRSYERAMDESFFPHIQ
PMNTFRDAATSIKHFPSVVYMETEVVPLALYQRFNKNFPFNEVRSVDAQLAAIRGIKSPYELSLMEQSGHIHQLVLEEYV
PKMLKEGMSEAKLASELFAVMVEEGHQGVTRVRSTDTEMVLGHIAFGESSIYPSYFYGPGGSYGMSPAVPLLGSRDRKLK
KGDLVFIDIGCGVGGYHTDKTMTYMFGESLPKEVISIHNKCVDIQHRTAEMLKPGAIPSEIYRSIMGSLDNGFRKNFMGF
GNGVLPFLGHGIGLEIDELPIIAEGFTEPLQEGMVFAVEPKKGIENIGMVGVENTFVVTPQGGRCITGDHPGLIPIY
>Mature_397_residues
MKNRVPFAELKIRMKRFRDKMKATNPDWQMVVIFSKVNIFYFTGTRQDGMLLIPREDEAIYWVRRSYERAMDESFFPHIQ
PMNTFRDAATSIKHFPSVVYMETEVVPLALYQRFNKNFPFNEVRSVDAQLAAIRGIKSPYELSLMEQSGHIHQLVLEEYV
PKMLKEGMSEAKLASELFAVMVEEGHQGVTRVRSTDTEMVLGHIAFGESSIYPSYFYGPGGSYGMSPAVPLLGSRDRKLK
KGDLVFIDIGCGVGGYHTDKTMTYMFGESLPKEVISIHNKCVDIQHRTAEMLKPGAIPSEIYRSIMGSLDNGFRKNFMGF
GNGVLPFLGHGIGLEIDELPIIAEGFTEPLQEGMVFAVEPKKGIENIGMVGVENTFVVTPQGGRCITGDHPGLIPIY

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 44662; Mature: 44662

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRVPFAELKIRMKRFRDKMKATNPDWQMVVIFSKVNIFYFTGTRQDGMLLIPREDEAI
CCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEECCCCCCEEEEECCCCEE
YWVRRSYERAMDESFFPHIQPMNTFRDAATSIKHFPSVVYMETEVVPLALYQRFNKNFPF
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCH
NEVRSVDAQLAAIRGIKSPYELSLMEQSGHIHQLVLEEYVPKMLKEGMSEAKLASELFAV
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
MVEEGHQGVTRVRSTDTEMVLGHIAFGESSIYPSYFYGPGGSYGMSPAVPLLGSRDRKLK
HHHCCCCCHHHHHCCCHHEEEEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCC
KGDLVFIDIGCGVGGYHTDKTMTYMFGESLPKEVISIHNKCVDIQHRTAEMLKPGAIPSE
CCCEEEEECCCCCCCCCCCCEEEEHHHCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHH
IYRSIMGSLDNGFRKNFMGFGNGVLPFLGHGIGLEIDELPIIAEGFTEPLQEGMVFAVEP
HHHHHHHHHCHHHHHHHHCCCCCCHHHHCCCCCCEECCCCEEHHHHHHHHHCCCEEEECC
KKGIENIGMVGVENTFVVTPQGGRCITGDHPGLIPIY
CCCCCCCCEEEECCEEEECCCCCEEECCCCCCEEECC
>Mature Secondary Structure
MKNRVPFAELKIRMKRFRDKMKATNPDWQMVVIFSKVNIFYFTGTRQDGMLLIPREDEAI
CCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEEEECCCCCCEEEEECCCCEE
YWVRRSYERAMDESFFPHIQPMNTFRDAATSIKHFPSVVYMETEVVPLALYQRFNKNFPF
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCH
NEVRSVDAQLAAIRGIKSPYELSLMEQSGHIHQLVLEEYVPKMLKEGMSEAKLASELFAV
HHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
MVEEGHQGVTRVRSTDTEMVLGHIAFGESSIYPSYFYGPGGSYGMSPAVPLLGSRDRKLK
HHHCCCCCHHHHHCCCHHEEEEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCC
KGDLVFIDIGCGVGGYHTDKTMTYMFGESLPKEVISIHNKCVDIQHRTAEMLKPGAIPSE
CCCEEEEECCCCCCCCCCCCEEEEHHHCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHH
IYRSIMGSLDNGFRKNFMGFGNGVLPFLGHGIGLEIDELPIIAEGFTEPLQEGMVFAVEP
HHHHHHHHHCHHHHHHHHCCCCCCHHHHCCCCCCEECCCCEEHHHHHHHHHCCCEEEECC
KKGIENIGMVGVENTFVVTPQGGRCITGDHPGLIPIY
CCCCCCCCEEEECCEEEECCCCCEEECCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]